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Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Tetraspanin CD81 Supports Cancer Stem Cell Function and Represents a Therapeutic Vulnerability in Acute Myeloid Leukemia

Fanny Gonzales, Pauline Peyrouze, Thomas Boyer, Soizic Guihard, Francois Sevrin, Djohana Laurent, Adriana Plesa, Adeline Barthelemy, Antonino Bongiovanni, Claude Preudhomme, Nicolas Duployez, Celine Berthon, Christophe Roumier, Meyling H Cheok
Journal: Blood
Blood (2023) 142 (Supplement 1): 168.
https://doi.org/10.1182/blood-2023-186957
Published: 2023
Journal Articles

Impact of Arsenic Trioxide in the Treatment of Higher Risk Acute Promyelocytic Leukemia

Audrey Da Rocha, Bruno Cassinat, Mael Heiblig, Christian Recher, Sarah Bertoli, Caroline Bonmati, Gabrielle Roth-Guepin, Anne Zilliox, Marie Laloi, Mathilde Hunault, Céline Berthon, Nicolas Duployez, Christophe Willekens, Maria Pilar Gallego Hernanz, Marlene Ochmann, Thomas Cluzeau, Fatiha Chermat, Alexis Caulier, Emmanuel Raffoux, Pierre Fenaux, Jean Pierre Marolleau, Lionel Ades, Delphine Lebon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1471.
https://doi.org/10.1182/blood-2023-174446
Published: 2023
Journal Articles

Clonal Dynamics of FLT3 -ITD Positive Acute Myeloid Leukemia Patients with Relapsed/Refractory Disease Following Intensive Chemotherapy +/- Midostaurin

Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Herve Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Lamya Haddaoui, Raphael Itzykson, Christian Recher, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 976.
https://doi.org/10.1182/blood-2023-182018
Published: 2023
Journal Articles

Impact of Residence in an Agricultural Zone on AML Characteristics

Vincent Marmouset, Berengere Gruson, Veronique Harrivel, Céline Berthon, Nicolas Duployez, Claude Preudhomme, Jean Pierre Marolleau, Pierre Morel, Carine Hauspie, Stéphane Morisset, Delphine Lebon
Journal: Blood
Blood (2023) 142 (Supplement 1): 2842.
https://doi.org/10.1182/blood-2023-173171
Published: 2023
Journal Articles

Oncogenetic-Driven Targeted Therapy for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia : A French ALL-Target Observatory Report

Aurelie Cabannes-Hamy, Lucien Courtois, Marie Balsat, Mathieu Simonin, Françoise Huguet, Martine Escoffre-Barbe, Florence Pasquier, Caroline Bonmati, Pascal Turlure, Thomas Cluzeau, Delphine Lebon, Eve Gehlkopf, Eolia Brissot, Justine Decroocq, Patrice Chevallier, Sylvain Chantepie, Victoria Cacheux, Sebastien Maury, Safia Chebrek, Thibaut Leguay, Melody Fort, Natacha Mauz, Mathlide Lamarque, Hunault-Berger Mathilde, Stefan Wickenhauser, Jamilé Frayfer, Anne Banos, Emmanuelle Tavernier, Denis Caillot, Anne Marie Ronchetti, Celine Berthon, Etienne Lengline, Véronique Lhéritier, Hervé Dombret, Ambroise Marçais, Antoine Pinton, Guillaume P Andrieu, Nicolas Boissel, Ludovic Lhermitte, Vahid Asnafi, Philippe Rousselot
Journal: Blood
Blood (2023) 142 (Supplement 1): 518.
https://doi.org/10.1182/blood-2023-179192
Published: 2023
Journal Articles

Mutational Profile and Dynamics of PPM1D -Mutant Clones in the Spectrum of Myeloid Disorders

Jean Pegliasco, David Fandrei, Florence Pasquier, Nathalie Ibrahim, Maria Kfoury, Guillemette Imbert-De-Tremiolles, Nourhan Lizziek, Céline Berthon, Mael Heiblig, Delphine Lebon, Ambroise Marcais, Mathieu Meunier, Ahmad Aljijakli, Emilie Lemasle, Sylvain Chantepie, Cécile Pautas, Pierre-Yves Dumas, Stephanie Haiat, Cyril Quivoron, Ileana antony-Debre, Sophie Cotteret, Raphael Itzykson, Hervé Dombret, Nicolas Duployez, Nathalie Droin, Christophe Marzac, Elsa Bernard, Jean-Baptiste Micol
Journal: Blood
Blood (2023) 142 (Supplement 1): 4064.
https://doi.org/10.1182/blood-2023-189428
Published: 2023
Journal Articles

Therapy Related Myeloid Neoplasms Following PARP Inhibitors : Real-Life Experience

Vincent Marmouset, Justine Decroocq, Sylvain Garciaz, Gabriel Etienne, Amine Belhabri, Sarah Bertoli, Lauris Gastaud, Celestine Simand, Sylvain Chantepie, Madalina Uzunov, Alexis Genthon, Celine Berthon, Edmond Chiche, Pierre-Yves Dumas, Jacques Vargaftig, Géraldine Salmeron, Emilie Lemasle, Emmanuelle Tavernier, Jeremy Delage, Marion Loirat, Nadine Morineau, Felix Blanc-Durand, Patricia Pautier, Veronique Vergé, Nathalie Auger, Myrtille Thomas, Laetitia Stefani, Marion Lepelley, Thomas Boyer, Sylvain Thepot, Marie-Pierre Gourin, Pascal Bourquard, Matthieu Duchmann, Pierre Morice, Mauricette Michallet, Lionel Ades, Pierre Fenaux, Christian Recher, Hervé Dombret, Arnaud Pages, Christophe Marzac, Alexandra Leary, Jean-Baptiste Micol
Journal: Blood
Blood (2022) 140 (Supplement 1): 12335–12338.
https://doi.org/10.1182/blood-2022-163478
Published: 2022
Journal Articles

Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Sébastien Maury, Anne Thiebaut-Bertrand, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre-Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Ioana Vaida, Laurence Sanhes, Magda Alexis, Cedric Pastoret, Mathlide Lamarque, Laure Farnault, Nathalie Grardel, Celine Berthon, Eric Delabesse, Veronique Lheritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 507–509.
https://doi.org/10.1182/blood-2022-159397
Published: 2022
Journal Articles

Safety and Pharmacokinetics of Subcutaneous Blinatumomab (SC blinatumomab) for the Treatment of Adults with Relapsed or Refractory B Cell Precursor Acute Lymphoblastic Leukemia (R/R B-ALL); Results from a Phase 1b Study

Pilar Martínez Sánchez, Gerhard Zugmaier, Paul Gordon, Elias Jabbour, José J. Rifón Roca, Stefan Schwartz, Erika Borlenghi, Francoise Huguet, Jesús María Hernández-Rivas, Federico Lussana, Céline Berthon, Priti Kadu, Hansen Wong, Ana Markovic, Yuliya Katlinskaya, Alessandro Rambaldi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6122–6124.
https://doi.org/10.1182/blood-2022-157117
Published: 2022
Journal Articles

Standard Risk-Assessment of AML Doesn't Predict the Outcome in Older AML Patients Undergoing Non-Intensive Chemotherapy

Laura Simon, Alexis Caulier, Celine Berthon, Thomas Boyer, Véronique Harrivel, Magalie Joris, Amandine Charbonnier, Etienne Paubelle, Isabelle Leduc, Nicolas Duployez, Christophe Roumier, Claude Preudhomme, Stéphane Morisset, Jean-Pierre Marolleau, Delphine Lebon
Journal: Blood
Blood (2022) 140 (Supplement 1): 3225–3226.
https://doi.org/10.1182/blood-2022-164840
Published: 2022
Journal Articles

LSC17 Score Is Complementary with Minimal Residual Disease to Stratify NPM1 -Mutated Acute Myeloid Leukemia: An ALFA Study

Loïc Vasseur, Laurène Fenwarth, Xavier Thomas, Jérôme Lambert, Stéphane de Botton, Martin Figeac, Céline Villenet, Pierre-Yves Dumas, Christian Recher, Céline Berthon, Emilie Lemasle, Delphine Lebon, Juliette Lambert, Christine Terré, Karine Celli-Lebras, Hervé Dombret, Claude Preudhomme, Meyling Cheok, Raphael Itzykson, Nicolas Duployez
Journal: Blood
Blood (2022) 140 (Supplement 1): 6303–6305.
https://doi.org/10.1182/blood-2022-163348
Published: 2022
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

The Omission of High-Dose Cytarabine during Consolidation Therapy of Ph-Positive ALL Patients Treated with Nilotinib and Low-Intensity Chemotherapy Results in an Increased Risk of Relapses Despite Non-Inferior Levels of Late BCR-ABL1 MRD Response. First Results of the Randomized Graaph-2014 Study

Philippe Rousselot, Yves Chalandon, Sylvie Chevret, Jean-Michel Cayuela, Francoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Celine Berthon, Norbert Vey, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Jean Pierre Marolleau, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Olivier Spertini, Veronique Lheritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 512.
https://doi.org/10.1182/blood-2021-148843
Published: 2021
Journal Articles

Frequency and Outcome of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with BCR-ABL1 Clonal Hematopoiesis after Blast Clearance: Results from the Graaph-2014 Trial

Rathana KIM, Philippe Rousselot, Jean-Michel Cayuela, Yves Chalandon, Marie Passet, Xavier Thomas, Nicole Straetmans, Patrice Chevallier, Francoise Huguet, Celine Berthon, Georg Stüssi, Sébastien Maury, Sylvain Chantepie, Jean-Baptiste Micol, Isabelle Plantier, Sylvie Chevret, Jean Soulier, Norbert Ifrah, Veronique Lheritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2021) 138 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2021-150126
Published: 2021
Journal Articles

Long Term Follow-up and Combined Phase 2 Results of Eprenetapopt (APR-246) and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A. Sallman, Rami S. Komrokji, Amy E. DeZern, Marie Sebert, Guillermo Garcia-Manero, Ramy Rahmé, David P. Steensma, Jacqueline Lehmann che, Gail J. Roboz, Isabelle Madelaine, Mikkael A. Sekeres, Pierre Peterlin, Kendra Sweet, Odile Beyne Rauzy, Andrew T. Kuykendall, Christian Recher, Amy F McLemore, Aspasia Stamatoullas, Ling Zhang, Lise Willems, Qianxing Mo, Emmanuel Raffoux, Lisa Nardelli, Celine Berthon, Najla Al Ali, Bruno Quesnel, Eric Padron, Greg Korbel, Eyal C. Attar, Hagop Kantarjian, Alan F. List, Lionel Ades, Jeffrey E. Lancet, Pierre Fenaux, Thomas Cluzeau
Journal: Blood
Blood (2021) 138 (Supplement 1): 246.
https://doi.org/10.1182/blood-2021-153286
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Margaux Sevin, Franck Debeurme, Lucie Laplane, Séverine Badel, Margot Morabito, Hanna L. Newman, Miguel Torres-Martin, Qin Yang, Bouchra Badaoui, Orianne Wagner-Ballon, Véronique Saada, Dorothée Sélimoglu-Buet, Laurence Kraus-Berthier, Sébastien Banquet, Alix Derreal, Pierre Fenaux, Raphael Itzykson, Thorsten Braun, Gabriel Etienne, Celine Berthon, Sylvain Thépot, Oliver Kepp, Guido Kroemer, Eric Padron, Maria E. Figueroa, Nathalie Droin, Eric Solary
Journal: Blood
Blood (2021) 137 (24): 3390–3402.
https://doi.org/10.1182/blood.2020008729
Published: 2021
Includes: Supplemental data