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Issue Archive

Volume 90, Issue 10
November 15 1997
Blood Cover Image for Volume 90, Issue 10

Table of Contents

EDITORIAL

IgG Biosynthesis: No “Immunoregulatory Feedback”
R.P. Junghans
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REVIEW ARTICLES

Contact System: A Vascular Biology Modulator With Anticoagulant, Profibrinolytic, Antiadhesive, and Proinflammatory Attributes
Robert W. Colman,Alvin H. Schmaier
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CLINICAL INTERVENTION AND THERAPEUTIC TRIALS

Results of High-Dose Therapy and Autologous Bone Marrow/Stem Cell Transplantation During Remission in Poor-Risk Intermediate- and High-Grade Lymphoma: International Index High and High-Intermediate Risk Group
Auayporn Nademanee,Arturo Molina,Margaret R. O'Donnell,Andrew Dagis,David S. Snyder,Pablo Parker,Anthony Stein,Eileen Smith,Ina Planás,Ashwin Kashyap,Ricardo Spielberger,Henry Fung,K.K. Wong,George Somlo,Kim Margolin,Warren Chow,Irena Sniecinski,Nayana Vora,Karl G. Blume,Joyce Niland,Stephen J. Forman
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Autologous Bone Marrow Transplantation for Patients With Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia Following MDS
Theo De Witte,Anja Van Biezen,Jo Hermans,Myriam Labopin,Volker Runde,Reuven Or,Giovanna Meloni,Salut Brunet Mauri,Angelo Carella,Jane Apperley,Alois Gratwohl,Jean-Pierre Laporte,for the Chronic and Acute Leukemia Working Parties of the European Group for Blood and Marrow Transplantation
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Hepatic Lesions of Chronic Disseminated Candidiasis May Become Invisible During Neutropenia
Bernhard C. Pestalozzi,Gabriel P. Krestin,Urs Schanz,Emanuel Jacky,Jürg Gmür
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Predictors of Long-Term Response to High-Dose Interferon Therapy in Type II Cryoglobulinemia Associated With Hepatitis C Virus Infection
Milvia Casato,Vincent Agnello,Leopoldo P. Pucillo,Glenn B. Knight,Marco Leoni,Savino Del Vecchio,Cristina Mazzilli,Guido Antonelli,Lorenzo Bonomo
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HEMATOPOIESIS

Increased Growth Promoting But Not Mast Cell Degranulation Potential of a Covalent Dimer of c-Kit Ligand
Karl H. Nocka,Beth A. Levine,Jone-Lone Ko,Peter M. Burch,Bryan E. Landgraf,Rita Segal,Robert Lobell
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Development of a Novel Selective Amplifier Gene for Controllable Expansion of Transduced Hematopoietic Cells
Keiko Ito,Yasuji Ueda,Masaki Kokubun,Masashi Urabe,Toshiya Inaba,Hiroyuki Mano,Hirofumi Hamada,Toshio Kitamura,Hideaki Mizoguchi,Tsuneaki Sakata,Mamoru Hasegawa,Keiya Ozawa
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Recombinant Human Interleukin-11 Directly Promotes Megakaryocytopoiesis In Vitro
Nadine S. Weich,Anlai Wang,Michael Fitzgerald,Tamlyn Yee Neben,Debra Donaldson,JoAnn Giannotti,Joanne Yetz-Aldape,Robert M. Leven,Katherine J. Turner
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Flt3 Ligand Enhances the Yield of Primitive Cells After Ex Vivo Cultivation of CD34+ CD38dim Cells and CD34+ CD38dim CD33dim HLA-DR+ Cells
Douglas C. Dooley,Mang Xiao,Barbara K. Oppenlander,J. Michael Plunkett,Stewart D. Lyman
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Mitogenic Responses Mediated Through the Proteinase-Activated Receptor-2 Are Induced by Expressed Forms of Mast Cell α- or β-Tryptases
Humayun Mirza,Valentina A. Schmidt,Claudia K. Derian,Jolyon Jesty,Wadie F. Bahou
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Development of Natural Killer Cells, B Lymphocytes, Macrophages, and Mast Cells From Single Hematopoietic Progenitors in Culture of Murine Fetal Liver Cells
Yuichi Aiba,Makio Ogawa
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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Enhanced Lipid Peroxidation in Patients Positive for Antiphospholipid Antibodies
Luigi Iuliano,Domenico Praticò,Domenico Ferro,Valerio Pittoni,Guido Valesini,John Lawson,Garret A. FitzGerald,Francesco Violi
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Regulation of Myosin Phosphatase Through Phosphorylation of the Myosin-Binding Subunit in Platelet Activation
Keiji Nakai,Yoshinori Suzuki,Hisakazu Kihira,Hideo Wada,Masanori Fujioka,Masaaki Ito,Takeshi Nakano,Kozo Kaibuchi,Hiroshi Shiku,Masakatsu Nishikawa
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Interacting Regions in the A1 and A2 Subunits of Factor VIIIa Identified by Zero-Length Cross-Linking
Lynn M. O'Brien,Christine F. Huggins,Philip J. Fay
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The Human Integrin β3 Gene Is 63 kb and Contains a 5′-UTR Sequence Regulating Expression
Calvin C. Wilhide,Ying Jin,Qingbin Guo,Lu Li,Su-Xia Li,Edwin Rubin,Paul F. Bray
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A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B
Hui-Feng Lin,Nobuyo Maeda,Oliver Smithies,David L. Straight,Darrel W. Stafford
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Mutations in the Human Factor XII Gene
Manfred Schloesser,Sacha Zeerleder,Gerd Lutze,Walter-Michael Halbmayer,Sigrun Hofferbert,Bernd Hinney,Heinz Koestering,Bernhard Lämmle,Gerhard Pindur,Karsten Thies,Michael Köhler,Wolfgang Engel
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IMMUNOBIOLOGY

A Recombinant Human scFv Anti-Rh(D) Antibody With Multiple Valences Using a C-Terminal Fragment of C4-Binding Protein
M. Tonye Libyh,D. Goossens,S. Oudin,N. Gupta,X. Dervillez,G. Juszczak,P. Cornillet,F. Bougy,B. Reveil,F. Philbert,T. Tabary,D. Klatzmann,P. Rouger,J.H.M. Cohen
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PU.1/Pip and Basic Helix Loop Helix Zipper Transcription Factors Interact With Binding Sites in the CD20 Promoter to Help Confer Lineage- and Stage-Specific Expression of CD20 in B Lymphocytes
Andreas Himmelmann,Agostino Riva,Gaye Lynn Wilson,Brian P. Lucas,Claire Thevenin,John H. Kehrl
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Structural and Functional Basis for JAK3-Deficient Severe Combined Immunodeficiency
Fabio Candotti,Scott A. Oakes,James A. Johnston,Silvia Giliani,Richard F. Schumacher,Patrizia Mella,Maurilia Fiorini,Alberto G. Ugazio,Raffaele Badolato,Luigi D. Notarangelo,Fabio Bozzi,Paolo Macchi,Dario Strina,Paolo Vezzoni,R. Michael Blaese,John J. O'Shea,Anna Villa
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Pooled Normal Human Polyspecific IgM Contains Neutralizing Anti-Idiotypes to IgG Autoantibodies of Autoimmune Patients and Protects From Experimental Autoimmune Disease
Vincent Hurez,Michel D. Kazatchkine,Tchavdar Vassilev,Sheela Ramanathan,Anastas Pashov,Bertrand Basuyaux,Yvonne de Kozak,Blanche Bellon,Srini V. Kaveri
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Early Onset of Immunoglobulin Heavy Chain Gene Rearrangements in Normal Human Bone Marrow CD34+ Cells
Frédéric Davi,Ahmad Faili,Catherine Gritti,Catherine Blanc,Caroline Laurent,Laurent Sutton,Christian Schmitt,Hélène Merle-Béral
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NEOPLASIA

Evidence for Copurification of HERV-K–Related Transcripts and a Reverse Transcriptase Activity in Human Platelets From Patients With Essential Thrombocythemia
Mark T. Boyd,Brian Foley,Isadore Brodsky
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Markedly Reduced Expression of Platelet c-mpl Receptor in Essential Thrombocythemia
Yoko Horikawa,Itaru Matsumura,Koji Hashimoto,Masamichi Shiraga,Satoru Kosugi,Seiji Tadokoro,Takashi Kato,Hiroshi Miyazaki,Yoshiaki Tomiyama,Yoshiyuki Kurata,Yuji Matsuzawa,Yuzuru Kanakura
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Elevated Serum CD44 Level Is Associated With Unfavorable Outcome in Non-Hodgkin's Lymphoma
Raija Ristamäki,Heikki Joensuu,Kimmo Lappalainen,Lasse Teerenhovi,Sirpa Jalkanen
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Immunocytochemical Diagnosis of Acute Promyelocytic Leukemia (M3) With the Monoclonal Antibody PG-M3 (Anti-PML)
Brunangelo Falini,Leonardo Flenghi,Marta Fagioli,Francesco Lo Coco,Iole Cordone,Daniela Diverio,Laura Pasqualucci,Andrea Biondi,Daniela Riganelli,Annette Orleth,Arcangelo Liso,Massimo F. Martelli,Pier-Giuseppe Pelicci,Stefano Pileri
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Folate Deficiency Delays the Onset But Increases the Incidence of Leukemia in Friend Virus-Infected Mice
Mark J. Koury,Don J. Park,Danko Martincic,Donald W. Horne,Vladimir Kravtsov,James A. Whitlock,Maria del Pilar Aguinaga,Prapaporn Kopsombut
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A Novel Chromosomal Translocation t(4; 14)(p16.3; q32) in Multiple Myeloma Involves the Fibroblast Growth-Factor Receptor 3 Gene
Raffaella Richelda,Domenica Ronchetti,Luca Baldini,Lilla Cro,Luigi Viggiano,Rosalia Marzella,Mariano Rocchi,Takemi Otsuki,Luigia Lombardi,Anna Teresa Maiolo,Antonino Neri
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Preferential Dissemination of B-Cell Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma to the Splenic Marginal Zone
Ming-Qing Du,Huai-Zheng Peng,Ahmet Dogan,Tim C. Diss,Haiqun Liu,Lang-Xing Pan,Robin P. Moseley,Michael J. Briskin,John K.C. Chan,Peter G. Isaacson
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Correlation Between Mutation in P53, p53 Expression, Cytogenetics, Histologic Type, and Survival in Patients With B-Cell Non-Hodgkin's Lymphoma
Prasad R.K. Koduru,Karthik Raju,Veena Vadmal,Geetha Menezes,Shefali Shah,Myron Susin,Jonathan Kolitz,John D. Broome
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The Plasmacytoma Resistance Gene, Pctr2, Delays the Onset of Tumorigenesis and Resides in the Telomeric Region of Chromosome 4
Beverly A. Mock,Janet Hartley,Paul Le Tissier,Judith S. Wax,Michael Potter
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The Role of Mig, the Monokine Induced by Interferon-γ, and IP-10, the Interferon-γ–Inducible Protein-10, in Tissue Necrosis and Vascular Damage Associated With Epstein-Barr Virus-Positive Lymphoproliferative Disease
Julie Teruya-Feldstein,Elaine S. Jaffe,Parris R. Burd,Hirokazu Kanegane,Douglas W. Kingma,Wyndham H. Wilson,Dan L. Longo,Giovanna Tosato
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p16INK4A Promotes Differentiation and Inhibits Apoptosis of JKB Acute Lymphoblastic Leukemia Cells
Mitsuyoshi Urashima,James A. DeCaprio,Dharminder Chauhan,Gerrard Teoh,Atsushi Ogata,Steven P. Treon,Yasutaka Hoshi,Kenneth C. Anderson
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HOXC4, HOXC5, and HOXC6 Expression in Non-Hodgkin's Lymphoma: Preferential Expression of the HOXC5 Gene in Primary Cutaneous Anaplastic T-Cell and Oro-Gastrointestinal Tract Mucosa-Associated B-Cell Lymphomas
Janet J. Bijl,Johan W. van Oostveen,Jan M.M. Walboomers,Anja Horstman,Adriaan J.C. van den Brule,Rein Willemze,Chris J.L.M. Meijer
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PHAGOCYTES

Biochemical and Molecular Characterization of Hereditary Myeloperoxidase Deficiency
Maurizio Romano,Pietro Dri,Liviana Dadalt,Pierluigi Patriarca,Francisco E. Baralle
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Murine Macrophage Mannose Receptor Promoter Is Regulated by the Transcription Factors PU.1 and SP1
Quentin Eichbaum,David Heney,David Raveh,Michael Chung,Mark Davidson,Judith Epstein,R. Alan B. Ezekowitz
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Tumor Necrosis Factor α-Induced Eosinophil Accumulation in Rat Skin Is Dependent on α4 Integrin/Vascular Cell Adhesion Molecule-1 Adhesion Pathways
Maria-Jesus Sanz,Adele Hartnell,Patricia Chisholm,Cindy Williams,Dawn Davies,Vivian B. Weg,Marc Feldmann,Mark A. Bolanowski,Roy R. Lobb,Sussan Nourshargh
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Intracellular Pool of Vascular Endothelial Growth Factor in Human Neutrophils
Murielle Gaudry,Olivier Brégerie,Valérie Andrieu,Jamel El Benna,Marie-Anne Pocidalo,Jacques Hakim
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Interleukin-10 Upregulates Tumor Necrosis Factor Receptor Type-II (p75) Gene Expression in Endotoxin-Stimulated Human Monocytes
Harold L. Dickensheets,Sherry L. Freeman,Michael F. Smith, Jr,Raymond P. Donnelly
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RED CELLS

Band 3 Peptides Block the Adherence of Sickle Cells to Endothelial Cells In Vitro
Bernard J.-M. Thevenin,Ian Crandall,Samir K. Ballas,Irwin W. Sherman,Stephen B. Shohet
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IRC011, a New Synthetic Chelator With Selective Interaction With Catabolic Red Blood Cell Iron: Evaluation in Hypertransfused Rats With Hepatocellular and Reticuloendothelial Radioiron Probes and in Iron-Loaded Rat Heart Cells in Culture
Gurion Rivkin,Gabriela Link,Elliot Simhon,Rosa L. Cyjon,Joseph Y. Klein,Chaim Hershko
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The Exon 46-Encoded Sequence Is Essential for Stability of Human Erythroid α-Spectrin and Heterodimer Formation
Rick Wilmotte,Sandra L. Harper,Jeanine A. Ursitti,Joëlle Maréchal,Jean Delaunay,David W. Speicher
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Exclusion of Three Candidate Genes as Determinants of Congenital Dyserythropoietic Anemia Type II (CDA-II)
Achille Iolascon,Emanuele Miraglia del Giudice,Silverio Perrotta,Matteo Granatiero,Leopoldo Zelante,Paolo Gasparini
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TRANSPLANTATION

Allogeneic Versus Autologous Bone Marrow Transplantation for Refractory and Recurrent Low-Grade Non-Hodgkin's Lymphoma
Leo F. Verdonck,Adriaan W. Dekker,Henk M. Lokhorst,Eefke J. Petersen,H. Karel Nieuwenhuis
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Donor Leukocyte Infusions Are Effective in Relapsed Multiple Myeloma After Allogeneic Bone Marrow Transplantation
H.M. Lokhorst,A. Schattenberg,J.J. Cornelissen,L.L.M. Thomas,L.F. Verdonck
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Failure of Immunologic Purging in Mantle Cell Lymphoma Assessed by Polymerase Chain Reaction Detection of Minimal Residual Disease
Niels S. Andersen,John W. Donovan,Joseph S. Borus,Christina M. Poor,Donna Neuberg,Jon C. Aster,Lee M. Nadler,Arnold S. Freedman,John G. Gribben
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Altered Tyrosine Phosphorylation Via the Very Late Antigen (VLA)/β1 Integrin Stimulation Is Associated With Impaired T-Cell Signaling Through VLA-4 After Allogeneic Bone Marrow Transplantation
Toshiya Sato,Yoshiyuki Ohashi,Kouichi Tachibana,Robert J. Soiffer,Jerome Ritz,Chikao Morimoto
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CORRESPONDENCE

Wilms Tumor Gene (wt1) mRNA Is Equally Expressed in Blast Cells From Acute Myeloid Leukemia and Normal CD34+ Progenitors
Ulrich Maurer,Eckhart Weidmann,Tunca Karakas,Dieter Hoelzer,Lothar Bergmann
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International Prognostic Scoring System and Other Prognostic Systems for Myelodysplastic Syndromes
Carlo L. Balduini,Roberta Guarnone,Alessandro Pecci,Esther Centenara,Edoardo Ascari
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A Cheaper and More Rapid Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method for the Detection of the HLA-H Gene Mutations Occurring in Hereditary Hemochromatosis
Caroline Lynas
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Neonatal Screening for the Hemochromatosis Defect
Lara M. Cullen,Lesa Summerville,Tina V. Glassick,Darrell H.G. Crawford,Lawrie W. Powell,Elizabeth C. Jazwinska
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A Prospective Study of Radiation Therapy-Associated Thrombocytopenia
Susan J. Knox,Anna Varghese,Waqqar Khan,Eric Chen,Michael MacManus,Gordon Ray,Karen Lee,Kathleen R. Lamborn
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ERRATA

ERRATUM
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