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Issue Archive

Volume 128, Issue 2
July 14 2016
Issue Cover

Table of Contents

BLOOD FLASHBACK

Mathé G, Amiel JL, Schwarzenberg L, et al. Successful allogenic bone marrow transplantation in man: chimerism, induced specific tolerance, and possible anti-leukemic effects. Blood. 1965;25(2):179-196.
View Articletitled, Mathé G, Amiel JL, Schwarzenberg L, et al. Successful allogenic bone marrow transplantation in man: chimerism, induced specific tolerance, and possible anti-leukemic effects. <em>Blood</em>. 1965;25(2):<span class="related-article">179-196</span>.

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Precision monitoring takes the stage
Clinical Trials & Observations
Mark Roschewski
View Articletitled, Precision monitoring takes the stage
INSIDE BLOOD COMMENTARY
A role for IFN during embryonic hematopoiesis
Marieke A. G. Essers
View Articletitled, A role for IFN during embryonic hematopoiesis
INSIDE BLOOD COMMENTARY
ALPS DNT cells: active senior living with mTOR
Carl E. Allen
View Articletitled, ALPS DNT cells: active senior living with mTOR
INSIDE BLOOD COMMENTARY
Pocket-sized iron regulators: one size fits all?
V. Nathan Subramaniam
View Articletitled, Pocket-sized iron regulators: one size fits all?
INSIDE BLOOD COMMENTARY
Up or out: polarity of VWF release
Ruben Bierings,Jan Voorberg
View Articletitled, Up or out: polarity of VWF release
INSIDE BLOOD COMMENTARY
Fill 'er up? Fill what up?
Pete Lollar
View Articletitled, Fill 'er up? Fill what up?

PERSPECTIVES

What is new in diagnosis and management of light chain amyloidosis?
Clinical Trials & Observations
Giovanni Palladini,Giampaolo Merlini
View Articletitled, What is new in diagnosis and management of light chain amyloidosis?

REVIEW ARTICLE

Protease-activated receptors in hemostasis
Marvin T. Nieman
View Articletitled, Protease-activated receptors in hemostasis

HOW I TREAT

How I treat patients with inherited bleeding disorders who need anticoagulant therapy
Clinical Trials & Observations
Karlyn Martin,Nigel S. Key
View Articletitled, How I treat patients with inherited bleeding disorders who need anticoagulant therapy

CLINICAL TRIALS AND OBSERVATIONS

Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma
Clinical Trials & Observations
Sarit E. Assouline,Torsten Holm Nielsen,Stephen Yu,Miguel Alcaide,Lauren Chong,David MacDonald,Axel Tosikyan,Vishal Kukreti,Abbas Kezouh,Tina Petrogiannis-Haliotis,Marco Albuquerque,Daniel Fornika,Sepideh Alamouti,Remi Froment,Celia M. T. Greenwood,Kathleen Klein Oros,Errol Camglioglu,Ayushi Sharma,Rosa Christodoulopoulos,Caroline Rousseau,Nathalie Johnson,Michael Crump,Ryan D. Morin,Koren K. Mann
View Articletitled, Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma
Supplemental data
Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity
Clinical Trials & Observations
Benjamin L. Lampson,Siddha N. Kasar,Tiago R. Matos,Elizabeth A. Morgan,Laura Rassenti,Matthew S. Davids,David C. Fisher,Arnold S. Freedman,Caron A. Jacobson,Philippe Armand,Jeremy S. Abramson,Jon E. Arnason,Thomas J. Kipps,Joshua Fein,Stacey Fernandes,John Hanna,Jerome Ritz,Haesook T. Kim,Jennifer R. Brown
View Articletitled, Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Interferon-α signaling promotes embryonic HSC maturation
Peter Geon Kim,Matthew C. Canver,Catherine Rhee,Samantha J. Ross,June V. Harriss,Ho-Chou Tu,Stuart H. Orkin,Haley O. Tucker,George Q. Daley
View Articletitled, Interferon-α signaling promotes embryonic HSC maturation
Supplemental data
Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice
Alya Zriwil,Charlotta Böiers,Lilian Wittmann,Joanna C. A. Green,Petter S. Woll,Sten Eirik W. Jacobsen,Ewa Sitnicka
View Articletitled, Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice
Supplemental data

IMMUNOBIOLOGY

Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome
Simon Völkl,Anne Rensing-Ehl,Andrea Allgäuer,Elisabeth Schreiner,Myriam Ricarda Lorenz,Jan Rohr,Christian Klemann,Ilka Fuchs,Volker Schuster,André O. von Bueren,Nora Naumann-Bartsch,Eleonora Gambineri,Kathrin Siepermann,Robin Kobbe,Michaela Nathrath,Peter D. Arkwright,Maurizio Miano,Klaus-Daniel Stachel,Markus Metzler,Klaus Schwarz,Anita N. Kremer,Carsten Speckmann,Stephan Ehl,Andreas Mackensen
View Articletitled, Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome
Supplemental data

LYMPHOID NEOPLASIA

Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma
Julie Marie Matthews,Shruti Bhatt,Matthew P. Patricelli,Tyzoon K. Nomanbhoy,Xiaoyu Jiang,Yasodha Natkunam,Andrew J. Gentles,Ezequiel Martinez,Daxing Zhu,Jennifer Rose Chapman,Elena Cortizas,Ragini Shyam,Shideh Chinichian,Ranjana Advani,Li Tan,Jianming Zhang,Hwan Geun Choi,Robert Tibshirani,Sara J. Buhrlage,Dita Gratzinger,Ramiro Verdun,Nathanael S. Gray,Izidore S. Lossos
View Articletitled, Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma
Supplemental data
A clinically relevant in vivo zebrafish model of human multiple myeloma to study preclinical therapeutic efficacy
Brief Report
Jianhong Lin,Weihong Zhang,Jian-Jun Zhao,Ariel H. Kwart,Chun Yang,Dongdong Ma,Xiubao Ren,Yu-Tzu Tai,Kenneth C. Anderson,Robert I. Handin,Nikhil C. Munshi
View Articletitled, A clinically relevant in vivo zebrafish model of human multiple myeloma to study preclinical therapeutic efficacy

MYELOID NEOPLASIA

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy
Ruxanda Moschoi,Véronique Imbert,Marielle Nebout,Johanna Chiche,Didier Mary,Thomas Prebet,Estelle Saland,Rémy Castellano,Laurent Pouyet,Yves Collette,Norbert Vey,Christian Chabannon,Christian Recher,Jean-Emmanuel Sarry,Damien Alcor,Jean-François Peyron,Emmanuel Griessinger
View Articletitled, Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera
Carla Casu,Paraskevi Rea Oikonomidou,Huiyong Chen,Vijay Nandi,Yelena Ginzburg,Princy Prasad,Robert E. Fleming,Yatrik M. Shah,Erika V. Valore,Elizabeta Nemeth,Tomas Ganz,Brian MacDonald,Stefano Rivella
View Articletitled, Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera
Supplemental data

THROMBOSIS AND HEMOSTASIS

von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells
Mafalda Lopes da Silva,Daniel F. Cutler
View Articletitled, von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells
Supplemental data
Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice
Brian Cooley,William Funkhouser,Dougald Monroe,Ashley Ezzell,David M. Mann,Feng-Chang Lin,Paul E. Monahan,Darrel W. Stafford
View Articletitled, Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice
FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors
Brief Report
Christoph J. Hofbauer,Sylvia Kepa,Michael Schemper,Peter Quehenberger,Sylvia Reitter-Pfoertner,Christine Mannhalter,Birgit M. Reipert,Ingrid Pabinger
View Articletitled, FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors
Supplemental data

TRANSPLANTATION

Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation
Takuya Sekine,David Marin,Kai Cao,Li Li,Pramod Mehta,Hila Shaim,Catherine Sobieski,Roy Jones,Betul Oran,Chitra Hosing,Gabriela Rondon,Abdullah Alsuliman,Silke Paust,Borje Andersson,Uday Popat,Partow Kebriaei,Muharrem Muftuoglu,Rafet Basar,Kayo Kondo,Yago Nieto,Nina Shah,Amanda Olson,Amin Alousi,Enli Liu,Anushruti Sarvaria,Simrit Parmar,Darius Armstrong-James,Nobuhiko Imahashi,Jeffrey Molldrem,Richard Champlin,Elizabeth J. Shpall,Katayoun Rezvani
View Articletitled, Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation
Supplemental data

BLOOD WORK

Amelanotic melanoma in the bone marrow
Shireen Kassam,Chirag Shah
View Articletitled, Amelanotic melanoma in the bone marrow
Acute myeloid leukemia with erythrophagocytosis indicative of KAT6A rearrangement
Audrey Montewis,Marion Eveillard
View Articletitled, Acute myeloid leukemia with erythrophagocytosis indicative of <em>KAT6A</em> rearrangement
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