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Salvage chemotherapy and autologous stem cell transplantation for transformed indolent lymphoma: a subset analysis of NCIC CTG LY12
Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia
Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib
Issue Archive
Table of Contents
INSIDE BLOOD COMMENTARIES
PLENARY PAPER
Red Cells, Iron, and Erythropoiesis
Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease
PLENARY PAPER
Red Cells, Iron, and Erythropoiesis
Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea
Camila Bononi Almeida,Lucas Eduardo Botelho Souza,Flavia Costa Leonardo,Fabio Trindade Maranhão Costa,Claudio C. Werneck,Dimas Tadeu Covas,Fernando Ferreira Costa,Nicola Conran
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Salvage chemotherapy and autologous stem cell transplantation for transformed indolent lymphoma: a subset analysis of NCIC CTG LY12
Clinical Trials & Observations
John Kuruvilla,David A. MacDonald,C. Tom Kouroukis,Matthew Cheung,Harold J. Olney,A. Robert Turner,Peter Anglin,Matthew Seftel,Walid Sabry Ismail,Stefano Luminari,Stephen Couban,Tara Baetz,Ralph M. Meyer,Annette E. Hay,Lois Shepherd,Marina S. Djurfeldt,Sameer Alamoudi,Bingshu E. Chen,Michael Crump
Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results
Clinical Trials & Observations
Michael L. Wang,Kristie A. Blum,Peter Martin,Andre Goy,Rebecca Auer,Brad S. Kahl,Wojciech Jurczak,Ranjana H. Advani,Jorge E. Romaguera,Michael E. Williams,Jacqueline C. Barrientos,Ewa Chmielowska,John Radford,Stephan Stilgenbauer,Martin Dreyling,Wieslaw Wiktor Jedrzejczak,Peter Johnson,Stephen E. Spurgeon,Liang Zhang,Linda Baher,Mei Cheng,Dana Lee,Darrin M. Beaupre,Simon Rule
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia
Clinical Trials & Observations
Dae-Young Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Young-Don Joo,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Sung-Nam Lim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Sung-Doo Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jung-Hee Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Je-Hwan Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Dong Hwan (Dennis) Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Kihyun Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Chul Won Jung,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Inho Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Sung-Soo Yoon,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Seonyang Park,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jae-Sook Ahn,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Deok-Hwan Yang,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Je-Jung Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Ho-Sup Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Yang Soo Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Yeung-Chul Mun,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Hawk Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jae Hoo Park,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Joon Ho Moon,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Sang Kyun Sohn,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Sang Min Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Won Sik Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Kyoung Ha Kim,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jong-Ho Won,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Myung Soo Hyun,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jinny Park,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Jae Hoon Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Ho-Jin Shin,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Joo-Seop Chung,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Hyewon Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Hyeon-Seok Eom,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Gyeong Won Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Young-Uk Cho,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Seongsoo Jang,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Chan-Jeoung Park,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Hyun-Sook Chi,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology,Kyoo-Hyung Lee,for the Adult Acute Lymphoblastic Leukemia Working Party of the Korean Society of Hematology
IMMUNOBIOLOGY
A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy
Amélie Bonaud,Sébastien Bender,Guy Touchard,Corinne Lacombe,Nivine Srour,Laurent Delpy,Christelle Oblet,Anne Druilhe,Nathalie Quellard,Vincent Javaugue,Michel Cogné,Frank Bridoux,Christophe Sirac
LYMPHOID NEOPLASIA
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
Patrick R. Hagner,Hon-Wah Man,Celia Fontanillo,Maria Wang,Suzana Couto,Mike Breider,Chad Bjorklund,Courtney G. Havens,Gang Lu,Emily Rychak,Heather Raymon,Rama Krishna Narla,Leo Barnes,Gody Khambatta,Hsiling Chiu,Jolanta Kosek,Jian Kang,Michael D. Amantangelo,Michelle Waldman,Antonia Lopez-Girona,Ti Cai,Michael Pourdehnad,Matthew Trotter,Thomas O. Daniel,Peter H. Schafer,Anke Klippel,Anjan Thakurta,Rajesh Chopra,Anita K. Gandhi
MYELOID NEOPLASIA
Correlation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib
Clinical Trials & Observations
Keyur P. Patel,Kate J. Newberry,Rajyalakshmi Luthra,Elias Jabbour,Sherry Pierce,Jorge Cortes,Rajesh Singh,Meenakshi Mehrotra,Mark J. Routbort,Madan Luthra,Taghi Manshouri,Fabio P. Santos,Hagop Kantarjian,Srdan Verstovsek
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
BLOOD WORK
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Cover Image
Cover Image
Platelet-forming cells of the mouse embryo appear in 2 waves, first as a primitive diploid population in the yolk sac, followed by polyploid megakaryocytes in the fetal liver. To investigate their emergence and dispersal throughout development, the whole embryonic day 10.5 embryo was stained and chemically cleared to reveal platelet-forming cells within the vasculature. See the article by Potts et al on page 807.
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