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Bleeding manifestations and management of children with persistent and chronic immune thrombocytopenia: data from the Intercontinental Cooperative ITP Study Group (ICIS)
Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia
Issue Archive
May 30 2013
Table of Contents
Inside Blood
Blood Work
Blood Forum
Blood Spotlight
Review Article
Clinical Trials and Observations
Bleeding manifestations and management of children with persistent and chronic immune thrombocytopenia: data from the Intercontinental Cooperative ITP Study Group (ICIS)
Clinical Trials & Observations
Cindy E. Neunert,George R. Buchanan,Paul Imbach,Paula H. B. Bolton-Maggs,Carolyn M. Bennett,Ellis Neufeld,Sara K. Vesely,Leah Adix,Victor S. Blanchette,Thomas Kühne,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants,for the Intercontinental Cooperative ITP Study Group Registry II Participants
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6
Mathias Witzens-Harig,Dirk Hose,Simone Jünger,Christina Pfirschke,Nisit Khandelwal,Ludmila Umansky,Anja Seckinger,Heinke Conrad,Bettina Brackertz,Thierry Rème,Brigitte Gueckel,Tobias Meißner,Michael Hundemer,Anthony D. Ho,Jean-Francois Rossi,Kai Neben,Helga Bernhard,Hartmut Goldschmidt,Bernard Klein,Philipp Beckhove
MYD88 L265P mutation in Waldenstrom macroglobulinemia
Stéphanie Poulain,Christophe Roumier,Audrey Decambron,Aline Renneville,Charles Herbaux,Elisabeth Bertrand,Sabine Tricot,Agnès Daudignon,Sylvie Galiègue-Zouitina,Valerie Soenen,Olivier Theisen,Nathalie Grardel,Olivier Nibourel,Catherine Roche-Lestienne,Bruno Quesnel,Patrick Duthilleul,Claude Preudhomme,Xavier Leleu
EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity
Junli Yan,Siok-Bian Ng,Jim Liang-Seah Tay,Baohong Lin,Tze Loong Koh,Joy Tan,Viknesvaran Selvarajan,Shaw-Cheng Liu,Chonglei Bi,Shi Wang,Shoa-Nian Choo,Norio Shimizu,Gaofeng Huang,Qiang Yu,Wee-Joo Chng
Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL
Anna Vardi,Antonis Dagklis,Lydia Scarfò,Diane Jelinek,Darren Newton,Fiona Bennett,Julia Almeida,Arancha Rodriguez-Caballero,Sallie Allgood,Mark Lanasa,Agostino Cortelezzi,Ester Orlandi,Silvio Veronese,Marco Montillo,Andy Rawstron,Tait Shanafelt,Alberto Orfao,Kostas Stamatopoulos,Paolo Ghia
Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program
Yong Li,Michael W. Gordon,Zijun Y. Xu-Monette,Carlo Visco,Alexander Tzankov,Dehui Zou,Lugui Qiu,Santiago Montes-Moreno,Karen Dybkaer,Attilio Orazi,Youli Zu,Govind Bhagat,Kristy L. Richards,Eric D. Hsi,William W. L. Choi,J. Han van Krieken,Qin Huang,Weiyun Ai,Maurilio Ponzoni,Andrés J. M. Ferreri,Jane N. Winter,Ronald S. Go,Miguel A. Piris,Michael B. Møller,Lin Wu,Michael Wang,Kenneth S. Ramos,L. Jeffrey Medeiros,Ken H. Young
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
Hanna L. M. Rajala,Samuli Eldfors,Heikki Kuusanmäki,Arjan J. van Adrichem,Thomas Olson,Sonja Lagström,Emma I. Andersson,Andres Jerez,Michael J. Clemente,Yiyi Yan,Dan Zhang,Andy Awwad,Pekka Ellonen,Olli Kallioniemi,Krister Wennerberg,Kimmo Porkka,Jaroslaw P. Maciejewski,Thomas P. Loughran, Jr,Caroline Heckman,Satu Mustjoki
Platelets and Thrombopoiesis
The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi
Mehran Ghasemzadeh,Zane S. Kaplan,Imala Alwis,Simone M. Schoenwaelder,Katrina J. Ashworth,Erik Westein,Ehteramolsadat Hosseini,Hatem H. Salem,Robyn Slattery,Shaun R. McColl,Michael J. Hickey,Zaverio M. Ruggeri,Yuping Yuan,Shaun P. Jackson
Red Cells, Iron, and Erythropoiesis
Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia
e-blood
Settara C. Chandrasekharappa,Francis P. Lach,Danielle C. Kimble,Aparna Kamat,Jamie K. Teer,Frank X. Donovan,Elizabeth Flynn,Shurjo K. Sen,Supawat Thongthip,Erica Sanborn,Agata Smogorzewska,Arleen D. Auerbach,Elaine A. Ostrander,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5,and NISC Comparative Sequencing Program5
Thrombosis and Hemostasis
Transplantation
Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation
Marcelo A. Fernández-Viña,John P. Klein,Michael Haagenson,Stephen R. Spellman,Claudio Anasetti,Harriet Noreen,Lee Ann Baxter-Lowe,Pedro Cano,Neal Flomenberg,Dennis L. Confer,Mary M. Horowitz,Machteld Oudshoorn,Effie W. Petersdorf,Michelle Setterholm,Richard Champlin,Stephanie J. Lee,Marcos de Lima
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Cover Image
Cover Image
The foreground image (from PDB structure 4E9G) shows the thymine in a T:G mismatch everted and poised for cleavage by the glycosylase domain of human MBD4. Base excision is postulated to be a crucial step leading to chromosomal breakage in B cell lymphoma translocations, following DNA deamination by AID. The background image shows a “double-hit” B cell lymphoma with both BCL2 and MYC translocations. See the article by Lu et al on page 4551.
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