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Journal Articles

Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape modulation

Guoyou Liu, Juhyun Kim, Nicole Nguyen, Lecong Zhou, Ann Dean

Blood (2024) 143 (22): 2300–2313.

https://doi.org/10.1182/blood.2023021287

Published: 2024

Includes: Supplemental data

Journal Articles

Connecting the dots from let-7 to HIC2 to HBG

Ann Dean

Blood (2024) 143 (19): 1886–1887.

https://doi.org/10.1182/blood.2024024191

Published: 2024

Journal Articles

Help on the way to unsilence HbF

Ann Dean

Blood (2023) 141 (22): 2670–2672.

https://doi.org/10.1182/blood.2023020345

Published: 2023

Journal Articles

Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis

Xiang Guo, Yangu Zhao, Juhyun Kim, Ann Dean

Blood (2022) 139 (24): 3532–3545.

https://doi.org/10.1182/blood.2021014308

Published: 2022

Includes: Supplemental data

Journal Articles

PU.1 chromosomal dynamics are linked to LDB1

Ann Dean

Blood (2018) 132 (25): 2615–2616.

https://doi.org/10.1182/blood-2018-10-880781

Published: 2018

Journal Articles

Fetal γ-globin genes are regulated by the BGLT3 long noncoding RNA locus

Maria Soledad Ivaldi, Luis Francisco Diaz, Lyubomira Chakalova, Jongjoo Lee, Ivan Krivega, Ann Dean

Blood (2018) 132 (18): 1963–1973.

https://doi.org/10.1182/blood-2018-07-862003

Published: 2018

Includes: Supplemental data

Journal Articles

New Concepts in Genome Regulation

Ann Dean, PhD, Jongjoo Lee, Ryan Dale, Ivan Krivega, PhD

Blood (2016) 128 (22): SCI-47.

https://doi.org/10.1182/blood.V128.22.SCI-47.SCI-47

Published: 2016

Journal Articles

Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

Ivan Krivega, Colleen Byrnes, Jaira F. de Vasconcellos, Y. Terry Lee, Megha Kaushal, Ann Dean, Jeffery L. Miller

Blood (2015) 126 (5): 665–672.

https://doi.org/10.1182/blood-2015-02-629972

Published: 2015

Includes: Supplemental data

Journal Articles

Inhibition of G9a Methyltransferase in Adult Human Erythroblasts Stimulates Fetal Hemoglobin Production By Facilitating Looping Between LCR and γ-Globin Gene

Ivan Krivega, Colleen Byrnes, Jaira F. de Vasconcellos, Y. Terry Lee, Megha Kaushal, Ann Dean, Jeffery L. Miller

Blood (2014) 124 (21): 332.

https://doi.org/10.1182/blood.V124.21.332.332

Published: 2014

Journal Articles

Using Forced Chromatin Looping To Overcome Developmental Silencing Of Embryonic and Fetal β-Type Globin Genes In Adult Erythroid Cells

Jeremy W Rupon, MD, PHD, Wulan Deng, PhD, Hongxin Wang, Philip D Gregory, PhD, Andreas Reik, PhD, Ann Dean, PhD, Gerd A. Blobel, MD, PhD

Blood (2013) 122 (21): 433.

https://doi.org/10.1182/blood.V122.21.433.433

Published: 2013

Journal Articles

Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation

LiQi Li, Johannes Freudenberg, Kairong Cui, Ryan Dale, Sang-Hyun Song, Ann Dean, Keji Zhao, Raja Jothi, Paul E. Love

Blood (2013) 121 (22): 4575–4585.

https://doi.org/10.1182/blood-2013-01-479451

Published: 2013

Includes: Supplemental data

Journal Articles

The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation

M. A. Bender, Tobias Ragoczy, Jongjoo Lee, Rachel Byron, Agnes Telling, Ann Dean, Mark Groudine

Blood (2012) 119 (16): 3820–3827.

https://doi.org/10.1182/blood-2011-09-380485

Published: 2012

Includes: Supplemental data

Journal Articles

Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells

Christine M. Kiefer, Jongjoo Lee, Chunhui Hou, Ryan K. Dale, Y. Terry Lee, Emily R. Meier, Jeffrey L. Miller, Ann Dean

Blood (2011) 118 (23): 6200–6208.

https://doi.org/10.1182/blood-2011-06-363101

Published: 2011

Includes: Supplemental data

Journal Articles

Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation

Sang-Hyun Song, AeRi Kim, Tobias Ragoczy, M. A. Bender, Mark Groudine, Ann Dean

Blood (2010) 116 (13): 2356–2364.

https://doi.org/10.1182/blood-2010-03-272252

Published: 2010

Includes: Supplemental data

Journal Articles

During Terminal Differentiation, HbF-Inducing Cytokines Cause Decreased Expression and Reduced Globin Locus Occupancy of BCL11A in Human Erythroblasts.

Orapan Sripichai, PhD, Christine M. Kiefer, PhD, Y. Terry Lee, MS, Emily Riehm Meier, MD, Colleen Byrnes, MS, Ann Dean, PhD, Jeffery L. Miller, MD

Blood (2009) 114 (22): 457.

https://doi.org/10.1182/blood.V114.22.457.457

Published: 2009

Journal Articles

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Orapan Sripichai, Christine M. Kiefer, Natarajan V. Bhanu, Toshihiko Tanno, Seung-Jae Noh, Sung-Ho Goh, J. Eric Russell, Cheryl L. Rognerud, Ching-Nan Ou, Patricia A. Oneal, Emily R. Meier, Nicole M. Gantt, Colleen Byrnes, Y. Terry Lee, Ann Dean, Jeffery L. Miller

Blood (2009) 114 (11): 2299–2306.

https://doi.org/10.1182/blood-2009-05-219386

Published: 2009

Includes: Supplemental data

Journal Articles

Short-chain fatty acid–mediated effects on erythropoiesis in primary definitive erythroid cells

Himanshu Bhatia, Jennifer L. Hallock, Amrita Dutta, Shay Karkashon, Lauren S. Sterner, Toru Miyazaki, Ann Dean, Jane A. Little

Blood (2009) 113 (25): 6440–6448.

https://doi.org/10.1182/blood-2008-09-171728

Published: 2009

Journal Articles

A Novel Model of Short Chain Fatty Acid (SCFA)- Mediated up-Regulation of Embryonic/Fetal Globin Genes during Definitive Erythropoiesis.

Himanshu Bhatia, MS, MD, Jennifer L. Hallock, BS, Lauren E. Sterner, BA, Shay Karkashon, BTech, Amrita Dutta, PhD, Toru Miyazaki, MD, PhD, Ann Dean, PhD, Jane Little, MD

Blood (2008) 112 (11): 1878.

https://doi.org/10.1182/blood.V112.11.1878.1878

Published: 2008

Journal Articles

Endogenous Elevations of Short Chain Fatty Acids (SCFAs) Can Up-Regulate Embryonic Globin Gene Expression.

Himanshu Bhatia, MD, Jennifer Hallock, BS, Lauren Sterner, BA, Toru Miyazaki, MD, PhD, Ann Dean, PhD, Jane Little, MD

Blood (2007) 110 (11): 1770.

https://doi.org/10.1182/blood.V110.11.1770.1770

Published: 2007

Journal Articles

Endogenous Elevations of Short Chain Fatty Acids Up-Regulate Embryonic Globin Gene Expression during Primitive Erythropoiesis.

Lauren Sterner, BA, Toru Miyazaki, MD, PhD, Larry Swift, PhD, Ann Dean, PhD, Jane Little, MD

Blood (2004) 104 (11): 1210.

https://doi.org/10.1182/blood.V104.11.1210.1210

Published: 2004

NARROW

Long noncoding RNA GATA2AS influences human erythropoiesis by transcription factor and chromatin landscape modulation

Connecting the dots from let-7 to HIC2 to HBG

Help on the way to unsilence HbF

Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis

PU.1 chromosomal dynamics are linked to LDB1

Fetal γ-globin genes are regulated by the BGLT3 long noncoding RNA locus

New Concepts in Genome Regulation

Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

Inhibition of G9a Methyltransferase in Adult Human Erythroblasts Stimulates Fetal Hemoglobin Production By Facilitating Looping Between LCR and γ-Globin Gene

Using Forced Chromatin Looping To Overcome Developmental Silencing Of Embryonic and Fetal β-Type Globin Genes In Adult Erythroid Cells

Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation

The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation

Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells

Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation

During Terminal Differentiation, HbF-Inducing Cytokines Cause Decreased Expression and Reduced Globin Locus Occupancy of BCL11A in Human Erythroblasts.

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Short-chain fatty acid–mediated effects on erythropoiesis in primary definitive erythroid cells

A Novel Model of Short Chain Fatty Acid (SCFA)- Mediated up-Regulation of Embryonic/Fetal Globin Genes during Definitive Erythropoiesis.

Endogenous Elevations of Short Chain Fatty Acids (SCFAs) Can Up-Regulate Embryonic Globin Gene Expression.

Endogenous Elevations of Short Chain Fatty Acids Up-Regulate Embryonic Globin Gene Expression during Primitive Erythropoiesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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