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Jane A. Little
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Journal Articles

Association of Health-Related Quality of Life and Work Productivity with Clinical Characteristics in Adults with Sickle Cell Disease

Julie Kanter, Sophie Lanzkron, Sana Saif Ur Rehman, Jane A. Little, Megan M. Ullman, Randall Curtis, Nicole Crook, Jonathan C. Roberts, Derek Robertson, Joanne Wu, Michael B. Nichol
Journal: Blood
Blood (2023) 142 (Supplement 1): 2377.
https://doi.org/10.1182/blood-2023-187822
Published: 2023
Journal Articles

Grndad and Disease Modifying Therapy (DMT): Shifts in Dmt Are Seen at the Adolescent/Young Adult Transition in Sickle Cell Disease in a Multi-Site Prospective Registry

Sophie Lanzkron, Deepa Manwani, Julie Kanter, Arpan A Sinha, Robin E. Miller, Robert Cronin, Seethal A Jacob, James Harper, Alan Randall Anderson, Marsha Treadwell, Amma T. Owusu-Ansah, Beng R. Fuh, Molly Mandernach, Jahnavi Gollamudi, Suzanne L Saccente, Stephanie A. Fritch Lilla, Melissa McNaull, Dana Marie LeBlanc, Kay Linn Saving, Stephanie H. Guarino, Marisol Betensky, Alice J. Cohen, Ashok B. Raj, Farzana A Sayani, Sanjay J. Shah, Shalu Narang, Bindu Kanathezhath Sathi, John J Strouse, Trisha E. Wong, Ofelia A. Alvarez, Srila Gopal, Jessica Liang, Daniel Semakula, Matthew Chang, Kenneth Rivlin, Sana Saif Ur Rehman, Lisa M Shook, Melissa Frei-Jones, Jane A. Little
Journal: Blood
Blood (2023) 142 (Supplement 1): 798.
https://doi.org/10.1182/blood-2023-174930
Published: 2023
Journal Articles

High-Altitude Hypoxia Is Common in Adults with Sickle Cell Disease

Mofiyinfoluwa Obadina, Sherri Morris, Tara Alin, Barbara LeVarge, Jane A. Little
Journal: Blood
Blood (2023) 142 (Supplement 1): 3894.
https://doi.org/10.1182/blood-2023-182439
Published: 2023
Journal Articles

Cluster Analysis Reveals Distinct Subgroups with Severe Pain in Sickle Cell Disease: A Cross-Sectional Study Using the Grndad Multi-Center Registry

Martha O Kenney, Samuel Wilson, Morgan Rosser, Sophie Lanzkron, Julie Kanter, Amma T. Owusu-Ansah, Alice J. Cohen, Deepa Manwani, Jane A. Little
Journal: Blood
Blood (2023) 142 (Supplement 1): 930.
https://doi.org/10.1182/blood-2023-189214
Published: 2023
Journal Articles

Steady-State Hemoglobin Is Associated with Self-Reported Ability to Perform Challenging Physical Function Activities, but Not Global Physical Function in Individuals with Sickle Cell Anemia

Elizabeth Linton, Jennifer Schrack, Julie Kanter, Deepa Manwani, Jane A. Little, Sophie Lanzkron
Journal: Blood
Blood (2023) 142 (Supplement 1): 3882.
https://doi.org/10.1182/blood-2023-188159
Published: 2023
Journal Articles

Voxelotor and Red Blood Cell Pyruvate Kinase Activator Affect Clot Strength in Sickle Cell Disease

Zoe Sekyonda, Calvin Abonga, Christopher A. Delianides, Solomon Oshabaheebwa, Jane A. Little, Michael A. Suster, Pedram Mohseni, Umut A. Gurkan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1114.
https://doi.org/10.1182/blood-2023-187577
Published: 2023
Journal Articles

RBC, heal thyself: PK activators in SCD

Jane A. Little
Journal: Blood
Blood (2022) 140 (19): 2005–2006.
https://doi.org/10.1182/blood.2022016930
Published: 2022
Journal Articles

Targeted Proteomics of Pulmonary Hypertension in Sickle Cell Disease

Varshini Babu, Jane A. Little, Claudia R. Morris, Roberto Machado, J Simon R Gibbs, Gregory J. Kato, Victor R. Gordeuk, Mark T. Gladwin, Yingze Zhang, Seyed Mehdi Nouraie
Journal: Blood
Blood (2021) 138 (Supplement 1): 981.
https://doi.org/10.1182/blood-2021-145645
Published: 2021
Journal Articles

Hypoxia Impact on Red Blood Cell-Mediated Microvascular Occlusion and Adhesion in Sickle Cell Disease and Sickle Cell Trait

Yuncheng Man, Zoe Sekyonda, Karamoja Monchamp, Ran An, Erdem Kucukal, Chiara Federici, Lalitha V Nayak, Jane A. Little, Umut A. Gurkan
Journal: Blood
Blood (2021) 138 (Supplement 1): 966.
https://doi.org/10.1182/blood-2021-149121
Published: 2021
Journal Articles

Early Evaluation of the Use of Crizanlizumab in Sickle Cell Disease: A National Alliance of Sickle Cell Centers Study

Julie Kanter, Gerhard Hellemann, Alice J. Cohen, Deepa Manwani, Modupe Idowu, Stephanie Guarino, Sana Saif Ur Rehman, Marsha Treadwell, E. Leila Jerome Clay, Amma Owusu-Ansah, Jane A. Little, Payal Desai, Mohan Madisetti, Sophie M. Lanzkron
Journal: Blood
Blood (2021) 138 (Supplement 1): 3113.
https://doi.org/10.1182/blood-2021-153136
Published: 2021
Journal Articles

Assessment of Red Blood Cell-Mediated Microvascular Occlusion in Sickle Cell Disease By a Novel Electrical Impedance-Based Microfluidic Device

Yuncheng Man, Debnath Maji, PhD, Ran An, PhD, Sanjay P Ahuja, MD, Jane A. Little, MD, Pedram Mohseni, PhD, Michael A Suster, PhD, Umut A. Gurkan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-138876
Published: 2020
Journal Articles

Contribution of Red Blood Cell Derived Extracellular Vesicles to Sickle Red Blood Cell Adhesion Discerned Using an Endothelialized Microfluidic Assay

Ran An, PhD, Yuncheng Man, Erdem Kucukal, PhD, Kevin Cheng, William Wulftange, Jane A. Little, MD, Umut A. Gurkan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-142176
Published: 2020
Journal Articles

The Grndad Registry: Contemporary Natural History Data and an Analysis of Real-World Patterns of Use and Limitations of Disease Modifying Therapy in Adults with SCD

Alexandra Boye-Doe, Elizabeth Brown, Charu Puri-Sharma, MS, Anjulika Chawla, MD, Joshua J Field, Lynne D. Neumayr, MD, Susan Padrino, MD, Payal Desai, MD, Deepa Manwani, MD, Sophie M. Lanzkron, MD MHS, Jane A. Little, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–36.
https://doi.org/10.1182/blood-2020-138895
Published: 2020
Journal Articles

Thrombin-Induced Endothelial Cell Damage Is Mitigated By Human Anti-Thrombin III in a Microfluidic Device

William Wulftange, Erdem Kucukal, PhD, Yuncheng Man, Ran An, PhD, Karamoja Monchamp, Olabimpe Olayiwola, MS, Jane A. Little, MD, Nigel S. Key, MD, Umut A. Gurkan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-141583
Published: 2020
Journal Articles

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Solomon Johnson, MS, Victor R. Gordeuk, MD, Roberto Machado, MD, J Simon R Gibbs, Mariana Hildesheim, MS, Jane A. Little, MD, Gregory J Kato, MD, Mark T Gladwin, MD, Seyed Mehdi Nouraie, PhD MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 59–60.
https://doi.org/10.1182/blood-2020-136393
Published: 2020
Journal Articles

Computer Vision and Deep Learning Assisted Microchip Electrophoresis for Integrated Anemia and Sickle Cell Disease Screening

Ran An, PhD, Yuncheng Man, Shamreen Iram, Erdem Kucukal, PhD, Muhammad Noman Hasan, PhD, Ambar Solis-Fuentes, Allison Bode, Ailis Hill, Kevin Cheng, Yuning Huang, Sanjay Ahuja, MD, Jane A. Little, MD, Michael Hinczewski, PhD, Umut A. Gurkan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-142548
Published: 2020
Journal Articles

Venous Thromboembolism (VTE) in Sickle Cell Disease (SCD) Is Associated with Neutrophilia

Jahnavi Gollamudi, MD, Shashank Sarvepalli, MD, Tara Alin, APRN-CNP, Animesh Vadaparti, M.Binf, Jane A. Little, MD, Lalitha V. Nayak, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 791.
https://doi.org/10.1182/blood-2019-128855
Published: 2019
Journal Articles

Chronic Kidney Disease Is Under-Screened in SCD and Mild Albuminuria Is Associated with a Drop in Hemoglobin: A Report from the Grndad Sickle Cell Registry

Elizabeth Williams, BA, Elizabeth Brown, Deepa Manwani, MD, Payal Desai, MD, Joshua J. Field, MD, Lynne D. Neumayr, Susan Padrino, MD, E. Leila Jerome Clay, MD MCTS, FAAP, Ze Cong, PhD, Irene Agodoa, MD, Carolyn Hoppe, MD, Sophie M. Lanzkron, MD, Jane A. Little, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2284.
https://doi.org/10.1182/blood-2019-124933
Published: 2019
Journal Articles

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia

Santosh L. Saraf, MD, Vimal K. Derebail, MD, Xu Zhang, PhD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Jane A. Little, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2268.
https://doi.org/10.1182/blood-2019-124737
Published: 2019
Journal Articles

International Multi-Site Clinical Validation of Point-of-Care Microchip Electrophoresis Test for Hemoglobin Variant Identification

Arwa Fraiwan, PhD, Muhammad Noman Hasan, MS, Ran An, PhD, Julia Z. Xu, MD MSc, Amy J. Rezac, Nicholas J. Kocmich, Tolulope Oginni, BS, Grace Mfon Olanipekun, Fatimah Hassan-Hanga, MD, Binta W. Jibir, MBBS MPH, Safiya Gambo, MBBS, Anil K. Verma, Praveen K. Bharti, Suchada Riolueang, MSc, Takdanai Ngimhung, Thidarat Suksangpleng, PhD, Priyaleela Thota, MD, Rajasubramaniam Shanmugam, PhD, Aparup Das, PhD, Vip Viprakasit, MD DPhil, Connie M. Piccone, MD, Jane A. Little, MD, Stephen K. Obaro, MD PhD, Umut A. Gurkan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3373.
https://doi.org/10.1182/blood-2019-129336
Published: 2019