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Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogeneic stem cell transplantation
Disease characteristics and clinical outcome in young adults with essential thrombocythemia versus early/prefibrotic primary myelofibrosis
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma
Issue Archive
July 19 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
Perspectives
Review Article
How I Treat
Clinical Trials and Observations
Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogeneic stem cell transplantation
Clinical Trials & Observations
Ajay K. Gopal,Radhakrishnan Ramchandren,Owen A. O'Connor,Robert B. Berryman,Ranjana H. Advani,Robert Chen,Scott E. Smith,Maureen Cooper,Achim Rothe,Jeffrey V. Matous,Laurie E. Grove,Jasmine Zain
Disease characteristics and clinical outcome in young adults with essential thrombocythemia versus early/prefibrotic primary myelofibrosis
Brief Report
Tiziano Barbui,Jürgen Thiele,Alessandra Carobbio,Francesco Passamonti,Elisa Rumi,Maria Luigia Randi,Irene Bertozzi,Alessandro M. Vannucchi,Heinz Gisslinger,Bettina Gisslinger,Guido Finazzi,Marco Ruggeri,Francesco Rodeghiero,Alessandro Rambaldi,Naseema Gangat,Ayalew Tefferi
Immunobiology
Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells
Sandra Martin-Latil,Nina F. Gnädig,Adeline Mallet,Marion Desdouits,Florence Guivel-Benhassine,Patricia Jeannin,Marie-Christine Prevost,Olivier Schwartz,Antoine Gessain,Simona Ozden,Pierre-Emmanuel Ceccaldi
Impaired natural killer cell self-education and “missing-self” responses in Ly49-deficient mice
Simon Bélanger,Megan M. Tu,Mir Munir Ahmed Rahim,Ahmad B. Mahmoud,Rajen Patel,Lee-Hwa Tai,Angela D. Troke,Brian T. Wilhelm,Josette-Renée Landry,Qinzhang Zhu,Kenneth S. Tung,David H. Raulet,Andrew P. Makrigiannis
Lymphoid Neoplasia
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma
e-blood
Richard W. J. Groen,Willy A. Noort,Reinier A. Raymakers,Henk-Jan Prins,Linda Aalders,Frans M. Hofhuis,Petra Moerer,Jeroen F. van Velzen,Andries C. Bloem,Berris van Kessel,Henk Rozemuller,Ellen van Binsbergen,Arjan Buijs,Huipin Yuan,Joost D. de Bruijn,Michel de Weers,Paul W. H. I. Parren,Jan Jacob Schuringa,Henk M. Lokhorst,Tuna Mutis,Anton C. M. Martens
Myeloid Neoplasia
Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability
Liran I. Shlush,Noa Chapal-Ilani,Rivka Adar,Neta Pery,Yosef Maruvka,Adam Spiro,Roni Shouval,Jacob M. Rowe,Maty Tzukerman,Dani Bercovich,Shai Izraeli,Guido Marcucci,Clara D. Bloomfield,Tsila Zuckerman,Karl Skorecki,Ehud Shapiro
Phagocytes, Granulocytes, and Myelopoiesis
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Transplantation
Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells
Rachelle G. Veenstra,Patricia A. Taylor,Qing Zhou,Angela Panoskaltsis-Mortari,Mitsuomi Hirashima,Ryan Flynn,Derek Liu,Ana C. Anderson,Terry B. Strom,Vijay K. Kuchroo,Bruce R. Blazar
Correspondence
Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia
Sara Ali,Ruhena Sergeant,Stephen G. O'Brien,Letizia Foroni,Corinne Hedgley,Gareth Gerrard,Dragana Milojkovic,Kate Stringaris,Ahmad Khoder,Abdullah Alsuliman,Maria Gilleece,Ian H. Gabriel,Nichola Cooper,John M. Goldman,Jane F. Apperley,Richard E. Clark,David Marin,Katayoun Rezvani
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Cover Image
Cover Image
![issue cover]()
In Hodgkin lymphoma, malignant CD30+ Hodgkin Reed-Sternberg (HRS) cells typically represent a small fraction (0.1% to 10%) of the nodal infiltrate. The cover image shows the distribution of HRS cells (red) among CD4+ T cells (green) in Hodgkin lymphoma tissue, with counterstained nuclei (blue). HRS cells and CD4+ T cells are detected with murine anti-CD30 and anti-CD4 antibodies, respectively; nuclei are counterstained with hematoxylin. The image was acquired with a Zeiss Axiovert 200M microscope (×40 objective). Immunohistochemical staining was enhanced using the Multispectral Nuance CRI Camera System to apply artificial fluorescent colors. Tissue from National Disease Research Interchange (NDRI), image by Dr M. Jonas, Seattle Genetics Inc. See the article by Gopal et al on page 560.
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