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Frans M. Hofhuis
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Journal Articles

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Refractory Patient-Derived Multiple Myeloma Cells, Growing in a Novel Humanized Mouse MM Model

Willy A Noort, PhD, Richard W.J. Groen, PhD, Reinier Raymakers, MD, PhD, Linda Aalders, Frans M Hofhuis, Berris Van Kessel, Jeroen F Van Velzen, Joost de Bruijn, PhD, Huipin Yuan, PhD, Jeroen Lammerts van Bueren, PhD, Andries C Bloem, PhD, Paul W.H.I. Parren, PhD, Henk Lokhorst, MD, Tuna Mutis, MD PhD, Anton C.M. Martens, PhD
Journal: Blood
Blood (2012) 120 (21): 940.
https://doi.org/10.1182/blood.V120.21.940.940
Published: 2012
Journal Articles

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

e-blood
Richard W. J. Groen, Willy A. Noort, Reinier A. Raymakers, Henk-Jan Prins, Linda Aalders, Frans M. Hofhuis, Petra Moerer, Jeroen F. van Velzen, Andries C. Bloem, Berris van Kessel, Henk Rozemuller, Ellen van Binsbergen, Arjan Buijs, Huipin Yuan, Joost D. de Bruijn, Michel de Weers, Paul W. H. I. Parren, Jan Jacob Schuringa, Henk M. Lokhorst, Tuna Mutis, Anton C. M. Martens
Journal: Blood
Blood (2012) 120 (3): e9–e16.
https://doi.org/10.1182/blood-2012-03-414920
Published: 2012
Includes: Supplemental data
Journal Articles

Reconstructing the Human Hematopoietic Niche: Opportunities for Studying Normal and Malignant Hematopoiesis,

Richard W Groen, PhD, Willy A Noort, PhD, Reinier Raymakers, MD, PhD, Henk-Jan Prins, Msc, Linda Aalders, Frans M Hofhuis, Berris van Kessel, Petra Moerer, Henk Rozemuller, PhD, Jan J. Schuringa, PhD, Joost de Bruijn, PhD, Michel de Weers, PhD, Paul W.H.I. Parren, PhD, Henk M. Lokhorst, MD, Tuna Mutis, MD PhD, Anton CM Martens, PhD
Journal: Blood
Blood (2011) 118 (21): 3412.
https://doi.org/10.1182/blood.V118.21.3412.3412
Published: 2011
Journal Articles

A Unique New Humanized Mouse Model for Multiple Myeloma (MM): Opportunities for Studying MM In Its Natural Environment and for Preclinical Testing

Richard W Groen, Frans M Hofhuis, Linda Aalders, Berris van Kessel, Michel de Weers, PhD, Tuna Mutis, MD, PhD, Henk Lokhorst, MD, PhD, Anton C Martens, PhD
Journal: Blood
Blood (2010) 116 (21): 981.
https://doi.org/10.1182/blood.V116.21.981.981
Published: 2010
Journal Articles

In Vitro and In Vivo Efficacy of CD38 Directed Therapy with Daratumumab In the Treatment of Multiple Myeloma

Richard W Groen, Michael van der Veer, Frans M Hofhuis, Berris van Kessel, Michel de Weers, PhD, Paul W.H.I. Parren, PhD, Henk M Lokhorst, MD, PhD, Tuna Mutis, MD, PhD, Anton Martens, PhD
Journal: Blood
Blood (2010) 116 (21): 3058.
https://doi.org/10.1182/blood.V116.21.3058.3058
Published: 2010
Journal Articles

Protein kinase B (PKB/c-akt) regulates homing of hematopoietic progenitors through modulation of their adhesive and migratory properties

Miranda Buitenhuis, Edwin van der Linden, Laurien H. Ulfman, Frans M. Hofhuis, Marc B. Bierings, Paul J. Coffer
Journal: Blood
Blood (2010) 116 (13): 2373–2384.
https://doi.org/10.1182/blood-2009-10-250258
Published: 2010
Includes: Supplemental data
Journal Articles

The Humanized Multiple Myeloma Mouse Model: Opportunities for Studying the Pathogenesis of MM in Its Natural Environment.

Richard W.J. Groen, Frans M. Hofhuis, Henk-Jan Prins, Henk Rozemuller, PhD, Berris van Kessel, Michel de Weers, PhD, Henk Lokhorst, MD, PhD, Anton C.M. Martens, PhD
Journal: Blood
Blood (2009) 114 (22): 1847.
https://doi.org/10.1182/blood.V114.22.1847.1847
Published: 2009