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Richard W. J. Groen
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Journal Articles

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Zhihong Ren, Jeong Hyun Ahn, Hequn Liu, Yi-Hsuan Tsai, Natarajan V. Bhanu, Brian Koss, David F. Allison, Anqi Ma, Aaron J. Storey, Ping Wang, Samuel G. Mackintosh, Ricky D. Edmondson, Richard W. J. Groen, Anton C. Martens, Benjamin A. Garcia, Alan J. Tackett, Jian Jin, Ling Cai, Deyou Zheng, Gang Greg Wang
Journal: Blood
Blood (2019) 134 (14): 1176–1189.
https://doi.org/10.1182/blood.2019000578
Published: 2019
Includes: Supplemental data
Journal Articles

Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches

Antonella Antonelli, Willy A. Noort, Jenny Jaques, Bauke de Boer, Regina de Jong-Korlaar, Annet Z. Brouwers-Vos, Linda Lubbers-Aalders, Jeroen F. van Velzen, Andries C. Bloem, Huipin Yuan, Joost D. de Bruijn, Gert J. Ossenkoppele, Anton C. M. Martens, Edo Vellenga, Richard W. J. Groen, Jan Jacob Schuringa
Journal: Blood
Blood (2016) 128 (25): 2949–2959.
https://doi.org/10.1182/blood-2016-05-719021
Published: 2016
Includes: Supplemental data
Journal Articles

CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma

Clinical Trials & Observations
Inger S. Nijhof, Tineke Casneuf, Jeroen van Velzen, Berris van Kessel, Amy E. Axel, Khaja Syed, Richard W. J. Groen, Mark van Duin, Pieter Sonneveld, Monique C. Minnema, Sonja Zweegman, Christopher Chiu, Andries C. Bloem, Tuna Mutis, Henk M. Lokhorst, A. Kate Sasser, Niels W. C. J. van de Donk
Journal: Blood
Blood (2016) 128 (7): 959–970.
https://doi.org/10.1182/blood-2016-03-703439
Published: 2016
Includes: Supplemental data
Journal Articles

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

e-blood
Richard W. J. Groen, Willy A. Noort, Reinier A. Raymakers, Henk-Jan Prins, Linda Aalders, Frans M. Hofhuis, Petra Moerer, Jeroen F. van Velzen, Andries C. Bloem, Berris van Kessel, Henk Rozemuller, Ellen van Binsbergen, Arjan Buijs, Huipin Yuan, Joost D. de Bruijn, Michel de Weers, Paul W. H. I. Parren, Jan Jacob Schuringa, Henk M. Lokhorst, Tuna Mutis, Anton C. M. Martens
Journal: Blood
Blood (2012) 120 (3): e9–e16.
https://doi.org/10.1182/blood-2012-03-414920
Published: 2012
Includes: Supplemental data
Journal Articles

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

Rogier M. Reijmers, Richard W. J. Groen, Annemieke Kuil, Kees Weijer, Fiona C. Kimberley, Jan Paul Medema, Toin H. van Kuppevelt, Jin-Ping Li, Marcel Spaargaren, Steven T. Pals
Journal: Blood
Blood (2011) 117 (23): 6162–6171.
https://doi.org/10.1182/blood-2010-12-325522
Published: 2011
Journal Articles

Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma

Brief Report
Rogier M. Reijmers, Richard W. J. Groen, Henk Rozemuller, Annemieke Kuil, Anneke de Haan-Kramer, Tamás Csikós, Anton C. M. Martens, Marcel Spaargaren, Steven T. Pals
Journal: Blood
Blood (2010) 115 (3): 601–604.
https://doi.org/10.1182/blood-2009-02-204396
Published: 2010
Includes: Supplemental data
Journal Articles

Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma

Esther P. M. Tjin, Richard W. J. Groen, Irma Vogelzang, Patrick W. B. Derksen, Melanie D. Klok, Helen P. Meijer, Susanne van Eeden, Steven T. Pals, Marcel Spaargaren
Journal: Blood
Blood (2006) 107 (2): 760–768.
https://doi.org/10.1182/blood-2005-05-1929
Published: 2006