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Journal Articles

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Zhihong Ren, Jeong Hyun Ahn, Hequn Liu, Yi-Hsuan Tsai, Natarajan V. Bhanu, Brian Koss, David F. Allison, Anqi Ma, Aaron J. Storey, Ping Wang, Samuel G. Mackintosh, Ricky D. Edmondson, Richard W. J. Groen, Anton C. Martens, Benjamin A. Garcia, Alan J. Tackett, Jian Jin, Ling Cai, Deyou Zheng, Gang Greg Wang
Journal: Blood
Blood (2019) 134 (14): 1176–1189.
https://doi.org/10.1182/blood.2019000578
Published: 2019
Includes: Supplemental data
Journal Articles

Establishing Human Niche Xenograft Models for Myeloid and Lymphoid Leukemia Driven By MLL-AF9

Marco Carretta, MSc, Jennifer Jaques, Bauke de Boer, MSc, Huipin Yuan, PhD, Anton C. Martens, PhD, Edo Vellenga, MDPhD, Richard W.J. Groen, PhD, Jan Jacob Schuringa, PhD
Journal: Blood
Blood (2014) 124 (21): 4781.
https://doi.org/10.1182/blood.V124.21.4781.4781
Published: 2014
Journal Articles

Excessively High-Affinity Single-Chain Fragment Variable Region in a Chimeric Antigen Receptor Can Counteract T-Cell Proliferation

Keisuke Watanabe, MD, Seitaro Terakura, MD PhD, Susumu Uchiyama, PhD, Anton C. Martens, PhD, Tom van Meerten, PhD, Hitoshi Kiyoi, MD PhD, Tetsuya Nishida, MD PhD, Tomoki Naoe, MDPhD, Makoto Murata, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4799.
https://doi.org/10.1182/blood.V124.21.4799.4799
Published: 2014
Journal Articles

CD38 Chimeric Antigen Receptor Engineered T Cells As Therapeutic Tools for Multiple Myeloma

Esther Drent, Richard Groen, PhD, Willy A. Noort, PhD, Jeroen Lammerts van Bueren, PhD, Paul W.H.I. Parren, PhD, Jurgen H Kuball, MDPhD, Zsolt Sebestyen, PhD, Niels W.C.J. van de Donk, MDPhD, Anton C. Martens, PhD, Henk M. Lokhorst, MDPhD, Tuna Mutis, MDPhD
Journal: Blood
Blood (2014) 124 (21): 4759.
https://doi.org/10.1182/blood.V124.21.4759.4759
Published: 2014
Journal Articles

Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis

Pallavi Suhas Sontakke, MSC, Richard W.J. Groen, PhD, Katarzyna Koczula, MSC, Jennifer Jaques, Huipin Yuan, PhD, Ulrich Günther, PhD, Anton C. Martens, PhD, Edo Vellenga, MD PhD, Jan J. Schuringa, PhD
Journal: Blood
Blood (2014) 124 (21): 515.
https://doi.org/10.1182/blood.V124.21.515.515
Published: 2014
Journal Articles

Modulation of CD38 Expression Levels on Multiple Myeloma Tumor Cells By All- Trans Retinoic Acid Improves the Efficacy of the Anti-CD38 Monoclonal Antibody Daratumumab

Inger S. Nijhof, MD, Henk M. Lokhorst, MDPhD, Berris van Kessel, Richard W.J. Groen, PhD, Anton C. Martens, PhD, Parul Doshi, PhD, Saskia K. Klein, MDPhD, Tuna Mutis, MDPhD, Kate Sasser, Niels W.C.J. van de Donk, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2096.
https://doi.org/10.1182/blood.V124.21.2096.2096
Published: 2014
Journal Articles

A Unique New Humanized Mouse Model for Multiple Myeloma (MM): Opportunities for Studying MM In Its Natural Environment and for Preclinical Testing

Richard W Groen, Frans M Hofhuis, Linda Aalders, Berris van Kessel, Michel de Weers, PhD, Tuna Mutis, MD, PhD, Henk Lokhorst, MD, PhD, Anton C Martens, PhD
Journal: Blood
Blood (2010) 116 (21): 981.
https://doi.org/10.1182/blood.V116.21.981.981
Published: 2010
Journal Articles

Induction of Potent Anti-Tumor Effects by Original and TCR-Redirected CD4 + Cytotoxic T Cells.

Robbert M Spaapen, Kelly van den Oudenalder, Maureen van Elk, Tineke Aarts, Teun Guichelaar, Richard WJ Groen, Andries C Bloem, Gert Storm, Anton C Martens, Henk M Lokhorst, MD, PhD, Tuna Mutis, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1333.
https://doi.org/10.1182/blood.V114.22.1333.1333
Published: 2009
Journal Articles

A Novel In Vivo Animal Model for Human Multiple Myeloma Based on Bioluminescence Imaging of Tumor Cell Growth.

Anton C. Martens, PhD, Henk Rozemuller, PhD, Ellen van der Spek, MD, Lijnie Bogers-Boer, Niels van de Donk, MD, PhD, Andries Bloem, PhD, Henk M. Lokhorst, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3452.
https://doi.org/10.1182/blood.V106.11.3452.3452
Published: 2005