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Journal Articles

Towards the Next Generation CAR T Cells with TEGs: In Vivo Efficacy — Toxicity Profile in Xenografts of Primary Human AML Disease and Healthy Bone Marrow

Trudy Straetemans, PhD, Inez Johanna Gan, MSc, Sabine Heijhuurs, MSc, Guido Kierkels, MSc, Koen Jansen, BSc, Ruud Doorn, BSc, Tineke Aarts, BSc, Haakan Norrel, PhD, Zsolt Sebestyen, PhD, Jurgen Kuball, MD

Blood (2017) 130 (Supplement 1): 3336.

https://doi.org/10.1182/blood.V130.Suppl_1.3336.3336

Published: 2017

Journal Articles

The Survivin Suppressant YM155 Overcomes Microenvironment-Mediated Immune Resistance In a Humanized Multiple Myeloma Mouse Model

Sanne J. de Haart, MD, Monique C. Minnema, MD PhD, Julie H. Huang, PhD, Tineke Aarts-Riemens, Henk Lokhorst, Anton Martens, PhD, Constantine S. Mitsiades, MD, PhD, Tuna Mutis, MD, PhD

Blood (2013) 122 (21): 3250.

https://doi.org/10.1182/blood.V122.21.3250.3250

Published: 2013

Journal Articles

Microenvironment Shields Myeloma From Adoptive Immunotherapy by Cell Adhesion Mediated Immune Resistance (CAM-IR),

Sanne J de Haart, MD, Monique C. Minnema, MD PhD, Tineke Aarts-Riemens, Niels Bovenschen, PhD, Henk M. Lokhorst, MD, Tuna Mutis, MD PhD

Blood (2011) 118 (21): 4039.

https://doi.org/10.1182/blood.V118.21.4039.4039

Published: 2011

Journal Articles

Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing

Niels W.C.J. van de Donk, MD, PhD, Henk M. Lokhorst, MD, Maarten Emmelot, Tineke Aarts-Riemens, Douglas W. McMillin, PhD, Gullu Gorgun, PhD, Steffen Klippel, PhD, Eugen Dhimolea, PhD, Jana Jakubikova, PhD, Catriona A. Hayes, MD, Panisinee Lawasut, MD, Jake E Delmore, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Constantine S. Mitsiades, MD, PhD, Tuna Mutis, MD PhD

Blood (2011) 118 (21): 1838.

https://doi.org/10.1182/blood.V118.21.1838.1838

Published: 2011

Journal Articles

Host Dendritic Cell Vaccinations Combined with Donor Lymphocyte Infusions Induce Host and KLH Specific Immunity in Multiple Myeloma Patients.

Evelien Kneppers, Monique C. Minnema, MD, PhD, Tineke Aarts, Maarten E. Emmelot, Ineke Slaper-Cortenbach, PhD, Kasper Westinga, Tuna Mutis, MD, PhD, Henk M. Lokhorst, MD, PhD

Blood (2009) 114 (22): 2875.

https://doi.org/10.1182/blood.V114.22.2875.2875

Published: 2009

Journal Articles

Induction of Potent Anti-Tumor Effects by Original and TCR-Redirected CD4 + Cytotoxic T Cells.

Robbert M Spaapen, Kelly van den Oudenalder, Maureen van Elk, Tineke Aarts, Teun Guichelaar, Richard WJ Groen, Andries C Bloem, Gert Storm, Anton C Martens, Henk M Lokhorst, MD, PhD, Tuna Mutis, MD, PhD

Blood (2009) 114 (22): 1333.

https://doi.org/10.1182/blood.V114.22.1333.1333

Published: 2009

Journal Articles

Lenalidomide Is Highly Effective in Patients with Relapsed Multiple Myeloma Following Allogeneic Stem Cell Transplantation and Increases the Frequency of CD4 + FOXP3 + T Cells.

Monique C. Minnema, MD, Michael van der Veer, Tineke Aarts, Maarten Emmelot, Tuna Mutis, PhD, Henk M. Lokhorst, MD

Blood (2007) 110 (11): 2722.

https://doi.org/10.1182/blood.V110.11.2722.2722

Published: 2007

Journal Articles

The In Vivo Impact of Human Regulatory T Cells on the Graft Versus Tumor Effect.

Tuna Mutis, MD, PhD, Henk Rozemuller, PhD, Maarten E. Emmelot, Tineke Aarts-Riemens, Vivienne Verweij, Saskia Ebeling, PhD, Leo F. Verdonck, MD, PhD, Henk Lockhorst, MD, PhD, Anton Martens, PhD

Blood (2007) 110 (11): 349.

https://doi.org/10.1182/blood.V110.11.349.349

Published: 2007

Journal Articles

Generation of CD4 + Regulatory T Cells by Retroviral Transduction of CD4 + CD25 − T Cells Either with the Full-Length or with a Common Exon-2 Negative Variant of Human Foxp3.

Tuna Mutis, MD, PhD, Leo F. Verdonck, MD, PhD, Tineke Aarts-Riemens, Maarten Emmelot

Blood (2005) 106 (11): 3315.

https://doi.org/10.1182/blood.V106.11.3315.3315

Published: 2005

Journal Articles

Human CD4 + CD25 + Regulatory T Cells Effectively Control Xenogeneic-GvHD Induced by Autologous T Cells in Rag2 −/− γc −/− Immune-Deficient Mice.

Tuna Mutis, MD, PhD, Rozemarijn S. van Rijn, MD, Elles R. Simonetti, Tineke Aarts, Maarten Emmelot, Saskia B. Ebeling, PhD

Blood (2004) 104 (11): 301.

https://doi.org/10.1182/blood.V104.11.301.301

Published: 2004

Journal Articles

Generation of Graft-Versus-Leukemia (GVL)-Effector T Cells through Targeting of Leukemia-Associated HY Antigens Via TCR Transfer.

Roman Ivanov, MD, Samantha Hol, Tineke Aarts, Anton Hagenbeek, Saskia Ebeling

Blood (2004) 104 (11): 2117.

https://doi.org/10.1182/blood.V104.11.2117.2117

Published: 2004

NARROW

Towards the Next Generation CAR T Cells with TEGs: In Vivo Efficacy — Toxicity Profile in Xenografts of Primary Human AML Disease and Healthy Bone Marrow

The Survivin Suppressant YM155 Overcomes Microenvironment-Mediated Immune Resistance In a Humanized Multiple Myeloma Mouse Model

Microenvironment Shields Myeloma From Adoptive Immunotherapy by Cell Adhesion Mediated Immune Resistance (CAM-IR),

Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing

Host Dendritic Cell Vaccinations Combined with Donor Lymphocyte Infusions Induce Host and KLH Specific Immunity in Multiple Myeloma Patients.

Induction of Potent Anti-Tumor Effects by Original and TCR-Redirected CD4 + Cytotoxic T Cells.

Lenalidomide Is Highly Effective in Patients with Relapsed Multiple Myeloma Following Allogeneic Stem Cell Transplantation and Increases the Frequency of CD4 + FOXP3 + T Cells.

The In Vivo Impact of Human Regulatory T Cells on the Graft Versus Tumor Effect.

Generation of CD4 + Regulatory T Cells by Retroviral Transduction of CD4 + CD25 − T Cells Either with the Full-Length or with a Common Exon-2 Negative Variant of Human Foxp3.

Human CD4 + CD25 + Regulatory T Cells Effectively Control Xenogeneic-GvHD Induced by Autologous T Cells in Rag2 −/− γc −/− Immune-Deficient Mice.

Generation of Graft-Versus-Leukemia (GVL)-Effector T Cells through Targeting of Leukemia-Associated HY Antigens Via TCR Transfer.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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