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Journal Articles

Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease

Pichika Chantrathammachart, Nigel Mackman, Erica Sparkenbaugh, Jian-Guo Wang, Leslie V. Parise, Daniel Kirchhofer, Nigel S. Key, Rafal Pawlinski
Journal: Blood
Blood (2012) 120 (3): 636–646.
https://doi.org/10.1182/blood-2012-04-424143
Published: 2012
Journal Articles

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

Jian-Guo Wang, Julia E. Geddings, Maria M. Aleman, Jessica C. Cardenas, Pichika Chantrathammachart, Julie C. Williams, Daniel Kirchhofer, Vladimir Y. Bogdanov, Ronald R. Bach, Janusz Rak, Frank C. Church, Alisa S. Wolberg, Rafal Pawlinski, Nigel S. Key, Jen Jen Yeh, Nigel Mackman
Journal: Blood
Blood (2012) 119 (23): 5543–5552.
https://doi.org/10.1182/blood-2012-01-402156
Published: 2012
Journal Articles

Monocytic microparticles activate endothelial cells in an IL-1β–dependent manner

Jian-Guo Wang, Julie C. Williams, Beckley K. Davis, Ken Jacobson, Claire M. Doerschuk, Jenny P.-Y. Ting, Nigel Mackman
Journal: Blood
Blood (2011) 118 (8): 2366–2374.
https://doi.org/10.1182/blood-2011-01-330878
Published: 2011
Journal Articles

Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

Rafal Pawlinski, Jian-Guo Wang, A. Phillip Owens, III, Julie Williams, Silvio Antoniak, Michael Tencati, Thomas Luther, Jesse W. Rowley, Elizabeth N. Low, Andrew S. Weyrich, Nigel Mackman
Journal: Blood
Blood (2010) 116 (5): 806–814.
https://doi.org/10.1182/blood-2009-12-259267
Published: 2010
Includes: Supplemental data
Journal Articles

The Major Phagocyte Peroxidase-Derived Oxidant, HOSCN (Hypothiocyanous Acid), Induces Proinflammatory and Cytoprotective Gene Expression in Endothelium: A Mechanism for Microlocalized Regulation of Inflammation.

Shawn A. Mahmud, BA, Jian-Guo Wang, Ph.D., Peng Wei, M.S., Molly S. Thomas, Ph.D., John D. Belcher, Ph.D., Gregory M. Vercellotti, M.D., Arne Slungaard, M.D.
Journal: Blood
Blood (2007) 110 (11): 3295.
https://doi.org/10.1182/blood.V110.11.3295.3295
Published: 2007
Journal Articles

Regulation of Tissue Factor by NF-kB Transcription Factor p50 Is Essential for the Pathogeneses of Deep Vein Thrombosis and Arterial Restenosis.

Jian-Guo Geng, MD, PhD, Jian-Guo Wang, Ph.D., Nigel Mackman, Ph.D., Arne Slungaard, M.D., Yuqing Huo, M.D., Ph.D., Nigel S. Key, M.D.
Journal: Blood
Blood (2006) 108 (11): 1458.
https://doi.org/10.1182/blood.V108.11.1458.1458
Published: 2006
Journal Articles

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states

Jian-Guo Wang, Shawn A. Mahmud, Jacob A. Thompson, Jian-Guo Geng, Nigel S. Key, Arne Slungaard
Journal: Blood
Blood (2006) 107 (2): 558–565.
https://doi.org/10.1182/blood-2005-05-2152
Published: 2006