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Journal Articles

Delayed Neutrophil Engraftment in Autologous Transplant Patients with Very High CD34+ Cell Collections in a Single Apheresis

Megan Melody, Madelyn Burkart, Marcelo Villa, Fenlu Zhu, Jane N. Winter, Reem Karmali, Adam Yuh Lin, Leo I. Gordon, Kehinde Adekola, Jonathan Moreira, Seema Singhal, Jayesh Mehta
Journal: Blood
Blood (2022) 140 (Supplement 1): 4703–4704.
https://doi.org/10.1182/blood-2022-167872
Published: 2022
Journal Articles

Outcomes in Patients with Hematologic Malignancies Infected with Sars-Cov-2: The Northwestern University Experience

Carlos Galvez, MD, Imran Nizamuddin, MD, Emily Tuchman, MD, Peter Doukas, MD, Neha Reddy, MD, Jessica K. Altman, MD, Jane N. Winter, MD, Leo I. Gordon, MD, Dylan Barth, PharmD, BCPS, Nicole Hodgins, Barbara Pro, MD, Shuo Ma, MD PhD, Shira Dinner, MD, Olga Frankfurt, MD, Jayesh Mehta, MD, Seema Singhal, MD, Kehinde Adekola, MBBS,MS, Jonathan Moreira, MD, Sajal D Tanna, MD MPH, Firas Wehbe, MD PhD, Reem Karmali, MDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–16.
https://doi.org/10.1182/blood-2020-139495
Published: 2020
Journal Articles

Comprehensive Investigation of White Blood Cell and Gene Expression Profiles As Risk Factors for Multiple Myeloma in African Americans

Linda Kachuri, PhD MPH, Zhaohui Du, M.S., Niels Weinhold, PhD, Gregory Song, Kristin Alyse Rand, PhD MPH, David Van Den Berg, PhD, Amie Hwang, PhD MPH, Xin Sheng, MS, Victor Hom, M.S., Sikander Ailawadhi, MD, Ajay K Nooka, MDMPH, Seema Singhal, MD, Edward S. Peters, DMD, SM, SM, ScD, Cathryn Bock, PhD, Ann Mohrbacher, MD, Alexander Stram, M.S., Sonja I Berndt, PhD, William J. Blot, PhD, Esther M. John, Leslie Bernstein, PhD, M.S., Antoinette Stroup, PhD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Andrew Olshan, Wei Zheng, MD PhD, Sue Ann Ingles, PhD, Michael Press, PhDMD, John David Carpten, PhD, Stephen J Chanock, MD, Jayesh Mehta, MD, Graham A Colditz, MD DrPH, Jeffrey Wolf, Thomas G. Martin, III, MD, Mark A. Fiala, BS, Howard R. Terebelo, DO, Nalini Janakiraman, MD, Laurence Kolonel, MD, PhD, Kenneth C. Anderson, MD, Loic Le Marchand, MD, PhD, Daniel Auclair, Brian C.-H. Chiu, PhD, Daniel Stram, PhD, Ravi Vij, MBBS, Leon Bernal-Mizrachi, MD, Gareth Morgan, MD PhD, Jeffrey A. Zonder, Carol Ann Huff, MD, Sagar Lonial, Robert Z. Orlowski, MD, PhD, David Conti, PhD, Christopher A. Haiman, PhD, Elad Ziv, MD, John S Witte, PhD, Wendy Cozen, DO,MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4379.
https://doi.org/10.1182/blood-2019-129298
Published: 2019
Journal Articles

A Meta-Analysis of Genome-Wide Association Studies of Multiple Myeloma in Persons of African Ancestry [African-American Multiple Myeloma Study (AAMMS)] Identifies Suggestive Risk Variants

Zhaohui Du, M.S., Niels Weinhold, PhD, David Van Den Berg, PhD, Amie Hwang, PhD MPH, Xin Sheng, M.S., Victor Hom, M.S., Sikander Ailawadhi, Ajay K. Nooka, MDMPH, Seema Singhal, MD, Karen Pawlish, Sc.D, M.P.H, Edward S. Peters, DMD, SM, SM, ScD, Cathryn Bock, PhD, Ann Mohrbacher, MD, Alexander Stram, M.S., Donglei Hu, M.S., John Graff, PhD, M.S., Sonja I Berndt, PhD, William J. Blot, PhD, John David Carpten, PhD, Graham Casey, PhD, Victoria L. Stevens, PhD, Rick Kittles, PhD, Goodman Phyllis, M.S., Anselm Hennis, MB;BS, MSc., PhD DLSHTM, FRCP, FACP, Eric A. Klein, MD, Barbara Nemesure, Benjamin A. Rybicki, Janet Stanford, John Witte, PhD, Christine B. Ambrosone, Esther M. John, Leslie Bernstein, PhD, M.S., Antoinette Stroup, PhD, Andrew Olshan, Wei Zheng, MD PhD, Jennifer J. Hu, Regina Ziegler, PhD, M.P.H., Sarah J. Nyante, Elisa Bandera, Sue Ann Ingles, PhD, Jayesh Mehta, MD, Graham A Colditz, MD DrPH, Michael Tomasson, MD, Mark A. Fiala, BS, Howard Terebelo, DO, Nalini Janakiraman, MD, Laurence Kolonel, MD, PhD, Loic Le Marchand, MD, PhD, Kenneth C Anderson, MD, Elad Ziv, MD, Brian C.-H. Chiu, PhD, David Conti, PhD, Daniel Stram, PhD, Ravi Vij, MDMBA, Leon Bernal-Mizrachi, MD, Jeffrey A Zonder, MD, Gareth J. Morgan, MD PhD, Carol Ann Huff, MD, Robert Z. Orlowski, MD PhD, Sagar Lonial, MD, Christopher A. Haiman, PhD, Wendy Cozen, DO,MPH
Journal: Blood
Blood (2017) 130 (Supplement 1): 3058.
https://doi.org/10.1182/blood.V130.Suppl_1.3058.3058
Published: 2017
Journal Articles

HLA Haplotypes Are Associated with Multiple Myeloma Risk in the African American Multiple Myeloma Study (AAMMS)

Loren Gragert, PhD, Amie Hwang, PhD MPH, Leon Bernal-Mizrachi, MD, Sikander Ailawadhi, MD, Seema Singhal, MD, David J. Vandenberg, PhD, Xin Sheng, MS, Alexander Stram, M.S., David V. Conti, PhD, Kristin A. Rand, PhD, M.P.H., Chi Song, PhD, M.S., John J. Graff, PhD, M.S., Nalini Janakiraman, MD, Jayesh Mehta, MD, Daniel O. Stram, PhD, Cathryn Bock, PhD, Laurence Kolonel, MD, PhD, Graham A. Colditz, MD, DrPH, Ann Mohrbacher, MD, Edward S. Peters, D.D.S., PhD, Howard Terebelo, D.O., Ajay K Nooka, MD MPH, Ravi Vij, MD, African Ancestry Breast and Prostate Consortium, P N Hari, MD, Meral Beksac, MD, Brian C.-H. Chiu, PhD, Michael H. Tomasson, MD, Jeffrey Zonder, MD, Carol Ann Huff, MD, Robert Z. Orlowski, PhD, MD, Sagar Lonial, MD FACP, Christopher A. Haiman, ScD, Wendy Cozen, DO, MPH
Journal: Blood
Blood (2016) 128 (22): 3250.
https://doi.org/10.1182/blood.V128.22.3250.3250
Published: 2016
Journal Articles

Phase 2 Study of Carfilzomib (CFZ) with or without Filanesib (FIL) in Patients with Advanced Multiple Myeloma (MM)

Jeffrey A Zonder, MD, Saad Usmani, Emma C. Scott, MD, Craig C. Hofmeister, MD, Nikoletta Lendvai, MDPhD, Jesus G. Berdeja, MD, Larry D. Anderson, Jr., MD PhD, Parameswaran Hari, MBBS, MD MRCP, Seema Singhal, MD, Gregory Orloff, MD, Michael Craig, MD, Jason Valent, MD, Wes Lee, Lowell Hart, J Hrom, Stephano Tarantolo, Edward Faber, DO, Gary J Schiller, MD, Jennifer Schreiber, BS, Colleen Oliver, MSc, Selena A Rush, BS, Brian Tunquist, Mieke Ptaszynski, Noopur S. Raje, MD
Journal: Blood
Blood (2015) 126 (23): 728.
https://doi.org/10.1182/blood.V126.23.728.728
Published: 2015
Journal Articles

Genetic Susceptibility Markers of Multiple Myeloma in African-Americans

Kristin A Rand, PhD, M.P.H., Chi Song, M.S., Amie E. Hwang, PhD, M.P.H., Carol A. Huff, MD, Leon Bernal-Mizrachi, MD, Michael H Tomasson, MD, Sikander Ailawadhi, MD, David J. Van Den Berg, PhD, Xin Sheng, PhD, John J. Graff, PhD, M.S., David V. Conti, PhD, Todd Zimmerman, MD, Edward Peters, D.MD S.M, Sc.D., Seema Singhal, MD, Cathryn H. Bock, PhD, Karen Pawlish, M.P.H., Graham A Colditz, MD, Dr.PH., Xin Sheng, PhD, Alexander Stram, M.S., Sara S. Strom, PhD, Benjamin Rybicki, PhD, Rick Kittles, PhD, Howard Terebelo, DO, Janet Stanford, PhD, MPH, Phyllis J. Goodman, PhD, Sonja I Berndt, PhD, John Carpten, PhD, Anselm JM Hennis, MSc,PhD MRCP, FRCP, Lisa Chu, PhD, M.P.H., Graham Casey, PhD, W R Driver, MSPH, Eric A. Klein, MD, M. Christina Leske, MD MPH, Esther John, PhD, Adam Bryant Murphy, MD, Christine Neslund-Dudas, PhD, Victoria L. Stevens, PhD, Curtis Pettaway, MD, Wei Zheng, MD PhD MPH, Suh-Yuh Wu, M.A., John Witte, PhD, Siqun Lilly Zheng, MD, Jianfeng Xu, MD,Dr.PH, Nikhil C. Munshi, MD, Ann Hsing, PhD, Sue Ingles, PhD, Jayesh Mehta, MD, Lisa B. Signorello, PhD, Stephen Jacob Chanock, MD, Barbara Nemesure, PhD, Ann M Mohrbacher, MD, Nalini Janakiraman, MD, William J Blot, MD, Brian E. Henderson, MD, Laurence N. Kolonel, MD PhD, Kenneth C. Anderson, MD, Brian C-H Chiu, PhD, Jeffrey Zonder, MD, Robert Z. Orlowski, PhD MD, Sagar Lonial, MD, Daniel O. Stram, PhD, Christopher Haiman, Sc.D., Wendy Cozen, DO, MPH
Journal: Blood
Blood (2014) 124 (21): 2030.
https://doi.org/10.1182/blood.V124.21.2030.2030
Published: 2014
Journal Articles

Obesity In Young Adulthood Is Associated With Early Onset Multiple Myeloma In African Americans

Amie E. Hwang, Ph.D., M.P.H., Sikander Ailawadhi, M.D., Leon Bernal-Mizrachi, M.D., Todd M Zimmerman, MD, Christopher Haiman, Sc.D., David J. Van Den Berg, Ph.D., Karen Pawlish, M.P.H., Ann M. Mohrbacher, MD, Howard Terebelo, DO, Brenda M. Birmann, ScD, Daniel O. Stram, Ph.D., David V. Conti, Ph.D., Nalini Janakiraman, MD, Brian E. Henderson, M.D., Laurence N Kolonel, MD, PhD, Jayesh Mehta, MD, Graham A Colditz, M.D., Dr.PH., John J. Graff, Ph.D., M.S., Cathryn H. Bock, Ph.D., Edward Peters, D.M.D, S.M, S.M, Sc.D., Brian C-H Chiu, Ph.D., Michael H. Tomasson, MD, Seema Singhal, M.D., Carol Ann Huff, M.D., Jeffrey A. Zonder, MD, Robert Z. Orlowski, M.D., Ph.D., Sagar Lonial, M.D., Wendy Cozen, D.O., M.P.H.
Journal: Blood
Blood (2013) 122 (21): 1872.
https://doi.org/10.1182/blood.V122.21.1872.1872
Published: 2013
Journal Articles

Total Lymphoid Irradiation and High-Dose Chemotherapy with Autologous Blood Stem-Cell Transplantation for Relapsed and Refractory Hodgkin Lymphoma: Excellent Disease Control and Long-Term Survival Rates

Ryan D. Gentzler, MD, MS, Andrew M. Evens, DO, MSc, Alfred W. Rademaker, PhD, Bharat B Mittal, M.D., Adam M. Petrich, MD, Jessica K. Altman, MD, Olga Frankfurt, MD, Daina Variakojis, MD, Seema Singhal, M.D., Jayesh Mehta, MD, Joel R Green, MD, Stephanie Williams, MD, Lynne Kaminer, MD, Leo I. Gordon, MD, Jane N. Winter, MD
Journal: Blood
Blood (2012) 120 (21): 2024.
https://doi.org/10.1182/blood.V120.21.2024.2024
Published: 2012
Journal Articles

Explaining the Excess Risk of Multiple Myeloma in African-Americans

Wendy Cozen, D., O., M.P.H., Amie E. Hwang, Ph.D., M.P.H., Sikander Ailawadhi, MD, Seema Singhal, M.D., Carol Ann Huff, M.D., Leon Bernal-Mizrachi, M.D., Brian C-H Chiu, Ph.D., Elizabeth E Brown, Ph.D., Edward Peters, D.M.D, S.M, S.M, Sc.D., Karen Pawlish, M.P.H., Mohrbacher Ann, M.D., Cathryn H. Bock, Ph.D., Christopher Haiman, Sc.D., Daniel O. Stram, Ph.D., Kristin A Rand, M.P.H., Michael H. Tomasson, MD, Nidhi Jain, MD, David J. Van Den Berg, Ph.D., John J. Graff, Ph.D., M.S., Graham A Colditz, M.D., Dr.PH., Todd M Zimmerman, MD, Jeffrey Zonder, M.D., Robert Z. Orlowski, M.D., Ph.D., Sagar Lonial, MD
Journal: Blood
Blood (2012) 120 (21): 4002.
https://doi.org/10.1182/blood.V120.21.4002.4002
Published: 2012
Journal Articles

A Phase I Study of the Safety and Pharmacokinetics of Escalating Doses of MFGR1877S, a Fibroblast Growth Factor Receptor 3 (FGFR3) Antibody, in Patients with Relapsed or Refractory t(4;14)-Positive Multiple Myeloma

Suzanne Trudel, MD, P. Leif Bergsagel, MD, Seema Singhal, M.D., Ruben Niesvizky, MD, Raymond L. Comenzo, MD, William I. Bensinger, MD, Daniel Lebovic, MD, YounJeong Choi, Dan Lu, Dorothy French, Elicia Penuel, William Ho, MD, PhD, Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 4029.
https://doi.org/10.1182/blood.V120.21.4029.4029
Published: 2012
Journal Articles

A phase 1, multicenter, open-label, dose escalation study of elotuzumab in patients with advanced multiple myeloma

Clinical Trials & Observations
Jeffrey A. Zonder, Ann F. Mohrbacher, Seema Singhal, Frits van Rhee, William I. Bensinger, Han Ding, John Fry, Daniel E. H. Afar, Anil K. Singhal
Journal: Blood
Blood (2012) 120 (3): 552–559.
https://doi.org/10.1182/blood-2011-06-360552
Published: 2012
Journal Articles

Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy

Samuel K. McBrayer, Javelin C. Cheng, Seema Singhal, Nancy L. Krett, Steven T. Rosen, Mala Shanmugam
Journal: Blood
Blood (2012) 119 (20): 4686–4697.
https://doi.org/10.1182/blood-2011-09-377846
Published: 2012
Includes: Supplemental data
Journal Articles

Busulfan, Cyclophosphamide, and Etoposide (Bu/Cy/VP-16) Is An Effective Conditioning Regimen Prior to Allogeneic or Autologous Stem Cell Transplantation for Primary Refractory or Relapsed Non-Hodgkin’s Lymphoma

Neelima Vidula, MD, Borko Jovanovic, PhD, Jane N. Winter, MD, Jayesh Mehta, MD, Seema Singhal, MD, Stephanie F. Williams, MD, Olga Frankfurt, MD, Jessica K. Altman, MD, Joanne Monreal, AAS, Andrew M. Evens, DO, MSc, Leo I. Gordon, MD, FACP
Journal: Blood
Blood (2011) 118 (21): 4499.
https://doi.org/10.1182/blood.V118.21.4499.4499
Published: 2011
Journal Articles

A Phase 1b/2 Study of Prolonged Infusion Carfilzomib in Patients with Relapsed and/or Refractory (R/R) Multiple Myeloma: Updated Efficacy and Tolerability From the Completed 20/56mg/m 2 Expansion Cohort of PX-171-007

Kyriakos P Papadopoulos, MD, Peter Lee, MD, PhD, Seema Singhal, MD, Joseph R. Holahan, MD, David H. Vesole, MD, PhD, Steven T. Rosen, MD, FRCPA, Lori Kunkel, MD, Alison L. Hannah, MD, David S. Siegel, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2930.
https://doi.org/10.1182/blood.V118.21.2930.2930
Published: 2011
Journal Articles

Unfavorable Cytogenetic Characteristics Do Not Adversely Impact Response Rates in Patients with Relapsed and/or Refractory Multiple Myeloma Treated with Single-Agent Carfilzomib on the 003 (A1) Study

Andrzej J Jakubowiak, MD, PhD, David S. Siegel, MD, PhD, Seema Singhal, MD, Thomas Martin, MD, Sagar Lonial, MD, Vishal Kukreti, MD, FRCPC, Nizar Bahlis, MD, Asher Alban Chanan-Khan, Melissa Alsina, MD, George Somlo, MD, Francis K Buadi, M.D., Frederic J. Reu, MD, Kevin W. Song, MD, Lori Kunkel, MD, Sandra M. Wear, RN, Alvin F. Wong, PharmD, Robert Z. Orlowski, MD, PhD, A. Keith Stewart, MBA, MB, CHB, Sundar Jagannath, MD, Luhua Wang, MD
Journal: Blood
Blood (2011) 118 (21): 1875.
https://doi.org/10.1182/blood.V118.21.1875.1875
Published: 2011
Journal Articles

Integrated Safety From Phase 2 Studies of Monotherapy Carfilzomib in Patients with Relapsed and Refractory Multiple Myeloma (MM): An Updated Analysis

Seema Singhal, MD, David S. Siegel, MD, PhD, Thomas Martin, MD, Ravi Vij, MD, Luhua Wang, MD, Andrzej J Jakubowiak, MD, Sagar Lonial, MD, Vishal Kukreti, MD, FRCPC, Jeffrey A. Zonder, MD, Alvin F. Wong, PharmD, Leanne McCulloch, PharmD, Ashraf Z. Badros, MD, Ruben Niesvizky, MD, Robert Z. Orlowski, MD, PhD, A. Keith Stewart, MBA, MB, CHB, Debbi Kotlovker, MS, Sundar Jagannath, MD
Journal: Blood
Blood (2011) 118 (21): 1876.
https://doi.org/10.1182/blood.V118.21.1876.1876
Published: 2011
Journal Articles

Preliminary Results of a Phase 2 Study of PD 0332991 in Combination with Bortezomib and Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma

Ruben Niesvizky, MD, Luciano J Costa, MD, PhD, Nisreen A. Haideri, MD, Georg Hess, Seema Singhal, MD, Ivan Spicka, MD, PhD, Edward A. Stadtmauer, MD, Ashraf Z. Badros, MD, Marc S Raab, John L Jakubczak, PhD, Sindy T. Kim, BS, Sophia Randolph, MD, PhD, Scott A Ely, M.D., Selina Chen-Kiang, PhD
Journal: Blood
Blood (2011) 118 (21): 2940.
https://doi.org/10.1182/blood.V118.21.2940.2940
Published: 2011
Journal Articles

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

Clinical Trials & Observations
Meletios Dimopoulos, Robert Kyle, Jean-Paul Fermand, S. Vincent Rajkumar, Jesus San Miguel, Asher Chanan-Khan, Heinz Ludwig, Douglas Joshua, Jayesh Mehta, Morie Gertz, Hervé Avet-Loiseau, Meral Beksaç, Kenneth C. Anderson, Philippe Moreau, Seema Singhal, Hartmut Goldschmidt, Mario Boccadoro, Shaji Kumar, Sergio Giralt, Nikhil C. Munshi, Sundar Jagannath, on behalf of the International Myeloma Workshop Consensus Panel 3
Journal: Blood
Blood (2011) 117 (18): 4701–4705.
https://doi.org/10.1182/blood-2010-10-299529
Published: 2011
Journal Articles

How I treat elderly patients with myeloma

Jayesh Mehta, Michele Cavo, Seema Singhal
Journal: Blood
Blood (2010) 116 (13): 2215–2223.
https://doi.org/10.1182/blood-2009-10-163329
Published: 2010
Includes: Supplemental data