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Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients
Iron chelation therapy with deferasirox in patients with aplastic anemia: a subgroup analysis of 116 patients from the EPIC trial
Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial
Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells
Issue Archive
October 7 2010
In this Issue
Table of Contents
Inside blood
Blood Work
Plenary paper
TRANSPLANTATION
Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
Clinical Trials & Observations
Sarah Cooley,Daniel J. Weisdorf,Lisbeth A. Guethlein,John P. Klein,Tao Wang,Chap T. Le,Steven G. E. Marsh,Daniel Geraghty,Stephen Spellman,Michael D. Haagenson,Martha Ladner,Elizabeth Trachtenberg,Peter Parham,Jeffrey S. Miller
Perspectives
Review Article
Clinical Trials and Observations
Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients
Clinical Trials & Observations
Annemiek Broyl,Dirk Hose,Henk Lokhorst,Yvonne de Knegt,Justine Peeters,Anna Jauch,Uta Bertsch,Arjan Buijs,Marian Stevens-Kroef,H. Berna Beverloo,Edo Vellenga,Sonja Zweegman,Marie-Josée Kersten,Bronno van der Holt,Laila el Jarari,George Mulligan,Hartmut Goldschmidt,Mark van Duin,Pieter Sonneveld
Hematopoiesis and Stem Cells
Iron chelation therapy with deferasirox in patients with aplastic anemia: a subgroup analysis of 116 patients from the EPIC trial
Clinical Trials & Observations
Jong Wook Lee,Sung-Soo Yoon,Zhi Xiang Shen,Arnold Ganser,Hui-Chi Hsu,Dany Habr,Gabor Domokos,Bernard Roubert,John B. Porter,on behalf of the EPIC study investigators
Immunobiology
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia
Qing Zhou,Meghan E. Munger,Steven L. Highfill,Jakub Tolar,Brenda J. Weigel,Megan Riddle,Arlene H. Sharpe,Daniel A. Vallera,Miyuki Azuma,Bruce L. Levine,Carl H. June,William J. Murphy,David H. Munn,Bruce R. Blazar
Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
e-blood
Joao B. Oliveira,Jack J. Bleesing,Umberto Dianzani,Thomas A. Fleisher,Elaine S. Jaffe,Michael J. Lenardo,Frederic Rieux-Laucat,Richard M. Siegel,Helen C. Su,David T. Teachey,V. Koneti Rao
Lymphoid Neoplasia
Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial
Clinical Trials & Observations
Peter Dreger,Hartmut Döhner,Matthias Ritgen,Sebastian Böttcher,Raymonde Busch,Sascha Dietrich,Donald Bunjes,Sandra Cohen,Jörg Schubert,Ute Hegenbart,Dietrich Beelen,Matthias Zeis,Michael Stadler,Justin Hasenkamp,Lutz Uharek,Christof Scheid,Andreas Humpe,Thorsten Zenz,Dirk Winkler,Michael Hallek,Michael Kneba,Norbert Schmitz,Stephan Stilgenbauer,for the German CLL Study Group
Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
Clinical Trials & Observations
Arnt V. Kristen,Evangelos Giannitsis,Stephanie Lehrke,Ute Hegenbart,Matthias Konstandin,David Lindenmaier,Corina Merkle,Stefan Hardt,Philipp A. Schnabel,Christoph Röcken,Stefan O. Schonland,Anthony D. Ho,Thomas J. Dengler,Hugo A. Katus
Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia
Medhat Shehata,Susanne Schnabl,Dita Demirtas,Martin Hilgarth,Rainer Hubmann,Elena Ponath,Sigrun Badrnya,Claudia Lehner,Andrea Hoelbl,Markus Duechler,Alexander Gaiger,Christoph Zielinski,Josef D. Schwarzmeier,Ulrich Jaeger
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma
Jose A. Richter-Larrea,Eloy F. Robles,Vicente Fresquet,Elena Beltran,Antonio J. Rullan,Xabier Agirre,Maria José Calasanz,Carlos Panizo,Jose A. Richter,Jesus M. Hernandez,Jose Roman-Gomez,Felipe Prosper,Jose A. Martinez-Climent
Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells
Brief Report
Erin Hertlein,Georgia Triantafillou,Ellen J. Sass,Joshua D. Hessler,Xiaoli Zhang,David Jarjoura,David M. Lucas,Natarajan Muthusamy,David M. Goldenberg,Robert J. Lee,John C. Byrd
Phagocytes, Granulocytes, and Myelopoiesis
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Correspondence
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Cover Image
Cover Image
![issue cover]()
The cover image illustrates the enhanced phosphorylation of Akt1 (in green fluorescence) in purified CLL cells upon incubation with primary human bone marrow stromal cells demonstrated by fibronectin staining (in red). This marrow microenvironment model provides direct evidence that CLL cells adhere to and migrate through the marrow stromal cells and their matrix products and consequently acquire antiapoptotic and proliferation signals through the activation of the PI3-K/Akt pathway. See the article by Shehata et al on page 2513.
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