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Journal Articles

IGF1R signaling in perinatal mesenchymal stem cells determines definitive hematopoiesis in bone marrow

Qi Lou, Kaizheng Jiang, Xiaoqi Wang, Yuan Pan, Guo Qiu, Binghuo Wu, Lisha Yuan, Siyu Xie, Jian Chen, Quanhui Xu, Meng Zhao, Linjia Jiang

Blood (2024) 144 (26): 2773–2787.

https://doi.org/10.1182/blood.2024024258

Published: 2024

Includes: Supplemental data

Journal Articles

Expansion of GATA1 -Mutant Clones in Blood Samples of Patients with Transient Abnormal Myelopoiesis (TAM) during Clinical Follow up Heralds Transformation to Myeloid Leukemia Associated with Down Syndrome (ML-DS)

Jian Chen, Ryan Ripsman, Rose Vernier, Astra Schwertschkow, Adam Shlien, Johann K. Hitzler

Blood (2024) 144 (Supplement 1): 6137.

https://doi.org/10.1182/blood-2024-204116

Published: 2024

Journal Articles

The Challenge of Treating Relapsed Myeloid Leukemia in Children with Down Syndrome - a Targeted Analysis Using Patient-Derived Xenograft Models

Jian Chen, Mohamed M. Abdelhaleem, Johann K. Hitzler

Blood (2023) 142 (Supplement 1): 5743.

https://doi.org/10.1182/blood-2023-187455

Published: 2023

Journal Articles

The RIG-I–NRF2 axis regulates the mesenchymal stromal niche for bone marrow transplantation

Qi Lou, Kaizheng Jiang, Quanhui Xu, Lisha Yuan, Siyu Xie, Yuan Pan, Jian Chen, Jun Wu, Jiang Zhu, Linjia Jiang, Meng Zhao

Blood (2022) 139 (21): 3204–3221.

https://doi.org/10.1182/blood.2021013048

Published: 2022

Includes: Supplemental data

Journal Articles

Postnatally Acquired Mutations Underlie the Progression of Transient Leukemia to Myeloid Leukemia of Down Syndrome

Jian Chen, PhD, Yue Li, MD MSC, Fouad Yousif, Sagi Abelson, PhD, Sanaz Manteghi, PhD, John D. McPherson, PhD, Johann K. Hitzler, MD

Blood (2018) 132 (Supplement 1): 442.

https://doi.org/10.1182/blood-2018-99-117198

Published: 2018

Journal Articles

Clinical Efficacy of Therapies for Transfusion-Dependent Non-Severe Aplastic Anemia: A Retrospective Cohort Study in Multiple Hospitals

Shengyun Lin, Prof.Dr., Yan Yang, Hua Yin, Chang Huang, Jian Chen, Liqiang Wu, Jianping Shen, Baodong Ye, Zhiping Hu, Yiping Shen, Zhiyin Zheng, Wenyi Shen, MD, Xingyu Lu, Xuemei Wu, Guangsheng He, Jianyong Li, MD PhD

Blood (2018) 132 (Supplement 1): 5111.

https://doi.org/10.1182/blood-2018-99-118727

Published: 2018

Journal Articles

Prediction of Relapse Based on Remission ADAMTS13 Activity in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura

Camila Masias Castanon, MD, Clare Stevens, BS/CCRP, Lauren Jay, Haiwa Wu, Michael McGookey, Jian Chen, MD, James N. George, MD, Shangbin Yang, PhD, Spero R Cataland, MD

Blood (2017) 130 (Supplement 1): 4843.

https://doi.org/10.1182/blood.V130.Suppl_1.4843.4843

Published: 2017

Journal Articles

Evaluation of the Pharmacokinetics of AG-221, a Potent Mutant IDH2 Inhibitor, in Patients with IDH2-Mutation Positive Advanced Hematologic Malignancies in a Phase 1/2 Trial

Yue Gao, PhD, Bin Fan, PhD, Kha Le, PhD, Erika Manyak, BASc, Hua Yang, PhD, Katherine Yen, PhD, Sam Agresta, MD, Eyal C. Attar, MD, Jian Chen, PhD, Qiang Xu, PhD, Alessandra Tosolini, BS, Jay M. Mei, MD PhD, Anjan Thakurta, Robert D. Knight, MD, Yan Li, PhD

Blood (2015) 126 (23): 2509.

https://doi.org/10.1182/blood.V126.23.2509.2509

Published: 2015

Journal Articles

Time-Dependent Activation of Complement system during Storage of Platelet Product

Jian Chen, MD PhD, Shangbin Yang, PhD, Spero R Cataland, MD, Haifeng M Wu, MD

Blood (2014) 124 (21): 4287.

https://doi.org/10.1182/blood.V124.21.4287.4287

Published: 2014

Journal Articles

Differences of Somatic Mutations and Gene Expression in Blasts of Transient Leukemia and Acute Myeloid Leukemia of Down Syndrome

Jian Chen, PhD, Fouad Yousif, Timothy Beck, John D McPherson, PhD, Johann K. Hitzler, MD

Blood (2014) 124 (21): 2364.

https://doi.org/10.1182/blood.V124.21.2364.2364

Published: 2014

Journal Articles

High IDH1 Expression Is Associated with a Poor Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

Qiu-Ling Ma, Jing-Han Wang, Yun-gui Wang, Chao Hu, Qi-Tian Mu, Meng-Xia Yu, Lei Wang, Dong-Mei Wang, Min Yang, Xiu-Feng Yin, Fei-Fei Chen, Sha-Sha Lu, Jian Chen, Zhi-Juan Zhu, Sai-Juan Chen, PhD, MD, Jie Jin, MD

Blood (2014) 124 (21): 5314.

https://doi.org/10.1182/blood.V124.21.5314.5314

Published: 2014

Journal Articles

Niche Requirements of Transient Leukemia Cells in Down Syndrome

Agnieszka A. Wendorff, PhD, Jian Chen, PhD, Yue Li, MD, Johann K. Hitzler, MD

Blood (2012) 120 (21): 1753.

https://doi.org/10.1182/blood.V120.21.1753.1753

Published: 2012

Journal Articles

GATA1 mutations Outside the Blast Cell Population in Transient Leukemia of Down Syndrome

Jian Chen, PhD, Agnieszka Wendorff, PhD, Yue Li, MD, Johann K. Hitzler, MD

Blood (2011) 118 (21): 2562.

https://doi.org/10.1182/blood.V118.21.2562.2562

Published: 2011

Journal Articles

PTEN regulates collagen-induced platelet activation

Zhen Weng, Ding Li, Lin Zhang, Jian Chen, Changgeng Ruan, Guoqiang Chen, T. Kent Gartner, Junling Liu

Blood (2010) 116 (14): 2579–2581.

https://doi.org/10.1182/blood-2010-03-277236

Published: 2010

Includes: Supplemental data

Journal Articles

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

Freda H. Passam, Soheila Rahgozar, Miao Qi, Mark J. Raftery, Jason W. H. Wong, Kumiko Tanaka, Yiannis Ioannou, Jing Yun Zhang, Rosalie Gemmell, Jian Chen Qi, Bill Giannakopoulos, Will E. Hughes, Philip J. Hogg, Steven A. Krilis

Blood (2010) 116 (11): 1995–1997.

https://doi.org/10.1182/blood-2010-02-271494

Published: 2010

Journal Articles

Nucleophosmin Is Required for Macrophage Function and Maturation.

Paolo Sportoletti, MD, John G Clohessy, Luisa Riccardi, MD, Arati Khanna-Gupta, PhD, Jian Chen, Nancy Berliner, MD, Pier Paolo Pandolfi, MD, PhD

Blood (2009) 114 (22): 238.

https://doi.org/10.1182/blood.V114.22.238.238

Published: 2009

Journal Articles

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

Arati Khanna-Gupta, PhD, Jian Chen, Matthew Silver, BS, Hong Sun, Nirmalee Abayasekara, MS, Stephanie Halene, MD, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner, MD

Blood (2009) 114 (22): 2768.

https://doi.org/10.1182/blood.V114.22.2768.2768

Published: 2009

Journal Articles

Research of Gene Expression in Patients with Myelodysplastic Syndromes.

Bao-An Chen, Bo Zhang, Chong Gao, Guo-Hua Xia, Ze-ye Shao, Jia-Hua Ding, Jian Chen, Jun Wang, Hui-Hui Song, Wen Bao, Yue-Jiao Zhong, Xiao-Ping Pei, Fei Wang, Ning-Na Chen

Blood (2009) 114 (22): 4433.

https://doi.org/10.1182/blood.V114.22.4433.4433

Published: 2009

Journal Articles

Generation of a Factor Dependent Myeloid Cell Line from Nucleophosmin-1 Heterozygous (NPM-1+/−) Mouse Bone Marrow as a Model for 5q- MDS

Arati Khanna-Gupta, PhD, Hong Sun, Jian Chen, Stephanie Halene, MD, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner

Blood (2008) 112 (11): 852.

https://doi.org/10.1182/blood.V112.11.852.852

Published: 2008

Journal Articles

Synergistic Effect of Magnetic Nanopartical Fe 3 0 4 , Au and Daunomycin on K562/A02.

Bao-An Chen, MD, PhD, Yong-Yuan Dai, MD, Xue Mei Wang, PhD, Ren-Yun Zhang, MD, Feng Gao, MD, Jian Chen, MD, Chong Gao, MD, Yun-Yu Sun, MD, Jun Wang, MD, Gang Zhao, MD, Jia-Hua Ding, MD, Ning-Na Chen, MD, Xiao-Ping Pei, MD

Blood (2007) 110 (11): 4171.

https://doi.org/10.1182/blood.V110.11.4171.4171

Published: 2007

NARROW

IGF1R signaling in perinatal mesenchymal stem cells determines definitive hematopoiesis in bone marrow

Expansion of GATA1 -Mutant Clones in Blood Samples of Patients with Transient Abnormal Myelopoiesis (TAM) during Clinical Follow up Heralds Transformation to Myeloid Leukemia Associated with Down Syndrome (ML-DS)

The Challenge of Treating Relapsed Myeloid Leukemia in Children with Down Syndrome - a Targeted Analysis Using Patient-Derived Xenograft Models

The RIG-I–NRF2 axis regulates the mesenchymal stromal niche for bone marrow transplantation

Postnatally Acquired Mutations Underlie the Progression of Transient Leukemia to Myeloid Leukemia of Down Syndrome

Clinical Efficacy of Therapies for Transfusion-Dependent Non-Severe Aplastic Anemia: A Retrospective Cohort Study in Multiple Hospitals

Prediction of Relapse Based on Remission ADAMTS13 Activity in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura

Evaluation of the Pharmacokinetics of AG-221, a Potent Mutant IDH2 Inhibitor, in Patients with IDH2-Mutation Positive Advanced Hematologic Malignancies in a Phase 1/2 Trial

Time-Dependent Activation of Complement system during Storage of Platelet Product

Differences of Somatic Mutations and Gene Expression in Blasts of Transient Leukemia and Acute Myeloid Leukemia of Down Syndrome

High IDH1 Expression Is Associated with a Poor Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

Niche Requirements of Transient Leukemia Cells in Down Syndrome

GATA1 mutations Outside the Blast Cell Population in Transient Leukemia of Down Syndrome

PTEN regulates collagen-induced platelet activation

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

Nucleophosmin Is Required for Macrophage Function and Maturation.

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

Research of Gene Expression in Patients with Myelodysplastic Syndromes.

Generation of a Factor Dependent Myeloid Cell Line from Nucleophosmin-1 Heterozygous (NPM-1+/−) Mouse Bone Marrow as a Model for 5q- MDS

Synergistic Effect of Magnetic Nanopartical Fe 3 0 4 , Au and Daunomycin on K562/A02.

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American Society of Hematology

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American Society of Hematology

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