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Journal Articles

Bortezomib Induction and Maintenance in Patients with Newly Diagnosed Multiple Myeloma: Long-Term Follow-up of the HOVON-65/GMMG-HD4 Trial

Pieter Sonneveld, MD PhD, Hans-Juergen Salwender, MD, Bronno Van Der Holt, PhD, Laila el Jarari, Uta Bertsch, MD, Igor W. Blau, MD, Sonja Zweegman, Katja C. Weisel, Edo Vellenga, MDPhD, Michael Pfreundschuh, Annemiek Broijl, MD PhD, Christof Scheid, MDPhD, Shulamiet Wittebol, MD, Gerard M.J. Bos, MD PhD, Marjan Stevens-Kroef, Anna Jauch, Anna Potamianou, MD PhD, Dirk Hose, MD, Reinier Raymakers, MD PhD, Marinus Schaafsme, Marie Jose Kersten, MD PhD, Marinus van Marwijk Kooy, Ulrich Duehrsen, Prof. Dr. MD, Hans Walter Lindemann, MD, Peter Brossart, MD, Pierre Wijermans, Henk M. Lokhorst, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2015) 126 (23): 27.
https://doi.org/10.1182/blood.V126.23.27.27
Published: 2015
Journal Articles

Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System

Clinical Trials & Observations
Rowan Kuiper, Mark van Duin, Martin H. van Vliet, Annemiek Broijl, Bronno van der Holt, Laila el Jarari, Erik H. van Beers, George Mulligan, Hervé Avet-Loiseau, Walter M. Gregory, Gareth Morgan, Hartmut Goldschmidt, Henk M. Lokhorst, Pieter Sonneveld
Journal: Blood
Blood (2015) 126 (17): 1996–2004.
https://doi.org/10.1182/blood-2015-05-644039
Published: 2015
Includes: Supplemental data
Journal Articles

Comparison Of Conventional, FISH and GEP Prognostic Factors In Multiple Myeloma: Introducing a Novel Risk Stratification

Rowan Kuiper, Martin van Vliet, Annemiek Broyl, Yvonne de Knegt, Bronno van der Holt, Laila el Jarari, George Mulligan, Walter Gregory, PhD, Gareth J Morgan, MD PhD, Hartmut Goldschmidt, MD, Uta Bertsch, MD, Henk Lokhorst, Mark van Duin, Erik van Beers, Pieter Sonneveld, MD, Ph.D
Journal: Blood
Blood (2013) 122 (21): 3092.
https://doi.org/10.1182/blood.V122.21.3092.3092
Published: 2013
Journal Articles

Bortezomib Induction and Maintenance Treatment Improves Survival In Patients With Newly Diagnosed Multiple Myeloma:Extended Follow-Up Of The HOVON-65/GMMG-HD4 Trial

Pieter Sonneveld, MD, Ph.D, Christof Scheid, MD, Bronno van der Holt, Laila el Jarari, Uta Bertsch, MD, Hans Salwender, MD, Sonja Zweegman, MD PhD, Edo Vellenga, Annemiek Broyl, Igor Wolfgang Blau, MD, PhD, Katja Weisel, MD, Shulamit Wittebol, Gerard M.J. Bos, Prof MD PhD, Marjan Stevens, Ingo GH Schmidt-Wolf, MD, Michael Pfreundschuh, MD, Dirk Hose, Dr. med. dipl.-phys., Anna Jauch, PhD, Helgi van de Velde, Reinier Raymakers, MD, PhD, Martyn Ronald Schaafsma, Marie Jose Kersten, MD, PhD, Marinus van Marwijk Kooy, MD, PhD, Ulrich Duehrsen, MD, Hans Walter Lindemann, MD, Pierre W. Wijermans, MD, PhD, Henk Lokhorst, H. Goldschmidt
Journal: Blood
Blood (2013) 122 (21): 404.
https://doi.org/10.1182/blood.V122.21.404.404
Published: 2013
Journal Articles

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance

Brief Report
Annemiek Broyl, Rowan Kuiper, Mark van Duin, Bronno van der Holt, Laila el Jarari, Uta Bertsch, Sonja Zweegman, Arjan Buijs, Dirk Hose, Henk M. Lokhorst, Hartmut Goldschmidt, Pieter Sonneveld
Journal: Blood
Blood (2013) 121 (4): 624–627.
https://doi.org/10.1182/blood-2012-06-438101
Published: 2013
Includes: Supplemental data
Journal Articles

Relation Between Cereblon Expression and Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Thalidomide

Annemiek Broyl, MD, Rowan Kuiper, BSc, Mark van Duin, PhD, Bronno van der Holt, PhD, Laila el Jarari, MSc, Uta Bertsch, MD, Sonja Zweegman, MD, PhD, Arjan Buijs, PhD, Dirk Hose, MD, PhD, Henk Lokhorst, MD, PhD, Hartmut Goldschmidt, MD, PhD, Pieter Sonneveld, MD
Journal: Blood
Blood (2012) 120 (21): 3973.
https://doi.org/10.1182/blood.V120.21.3973.3973
Published: 2012
Journal Articles

Combining Information Regarding Chromosomal Aberrations t(4;14), Del(17p13) and the Copy Number of 1q21 with the International Staging System Classification Allows Stratification of Myeloma Patients Undergoing Autologous Stem Cell Transplantation: Results From the HOVON-65/GMMG HD4 Trial

Kai Neben, MD, Henk M. Lokhorst, MD, Anna Jauch, PhD, Uta Bertsch, MD, Thomas Hielscher, Christiane Heiss, Bronno van der Holt, PhD, Stefan Schmitt, Laila el Jarari, MSc, Hans J. Salwender, MD, Igor W. Blau, Michael Pfreundschuh, MD, Katja Weisel, MD, Ulrich Duehrsen, MD, Walter Lindemann, Christian Teschendorf, Hans Martin, Christof Scheid, Mathias Haenel, MD, Hans Guenter Derigs, Ullrich Graeven, Ingo GH Schmidt-Wolf, Norma Peter, Mohammed Wattad, MD, Steffen P Luntz, Annemiek Broyl, MD, Joerg Schubert, MD, Martin Hoffmann, Martin Goerner, MD, Jochen Tischler, Martin Kaufmann, MD, Marc S Raab, Anthony D. Ho, MD, Helgi van de Velde, MD, PhD, Dirk Hose, MD, Pieter Sonneveld, MD, PhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2011) 118 (21): 332.
https://doi.org/10.1182/blood.V118.21.332.332
Published: 2011
Journal Articles

A High-Risk Survival Classifier for Multiple Myeloma

Rowan Kuiper, BSc, Annemiek Broyl, MD, Yvonne de Knegt, BSc, Martin H. van Vliet, PhD, Erik H. van Beers, PhD, Bronno van der Holt, PhD, Laila el Jarari, MSc, George Mulligan, PhD, Gareth Morgan, MD, Walter M Gregory, PhD, Hartmut Goldschmidt, MD, Henk M. Lokhorst, MD, Mark van Duin, PhD, Pieter Sonneveld, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1800.
https://doi.org/10.1182/blood.V118.21.1800.1800
Published: 2011
Journal Articles

Development of Bortezomib Induced Peripheral Neuropathy (BiPN) In Multiple Myeloma: Incidence and Molecular Characterization In Newly Diagnosed Patients Treated with Bortezomib

Annemiek Broyl, MD, Sophie Corthals, Joost L.M. Jongen, MD, PhD, Bronno van der Holt, PhD, Rowan Kuiper, Yvonne de Knegt, Laila el Jarari, Uta Bertsch, MD, PhD, Henk Lokhorst, MD, PhD, Brian GM Durie, MD, PhD, Hartmut Goldschmidt, MD, PhD, Pieter Sonneveld, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 304.
https://doi.org/10.1182/blood.V116.21.304.304
Published: 2010
Journal Articles

Bortezomib-Based Induction Therapy Followed by Autologous Stem Cell Transplantation and Maintenance Therapy with Bortezomib Improves Outcome In Myeloma Patients with Gain 1q21 and t(4;14) - a Subgroup Analysis of the HOVON-65/GMMG-HD4 Trial

Hartmut Goldschmidt, Kai Neben, Uta Bertsch, Thomas Hielscher, Bronno van der Holt, Dirk Hose, Laila el Jarari, Hans Salwender, Igor Wolfgang Blau, Michael Pfreundschuh, Ulrich Duehrsen, Katja Weisel, Hans Martin, Walter Lindemann, Christian Teschendorf, Mathias Haenel, Christof Scheid, Helgi van de Velde, Hans Guenter Derigs, Martin Hoffmann, Norma Peter, Martin Kaufmann, Ingo Schmidt-Wolf, Anna Jauch, Henk M Lokhorst, Pieter Sonneveld
Journal: Blood
Blood (2010) 116 (21): 305.
https://doi.org/10.1182/blood.V116.21.305.305
Published: 2010
Journal Articles

HOVON-65/GMMG-HD4 Randomized Phase III Trial Comparing Bortezomib, Doxorubicin, Dexamethasone (PAD) Vs VAD Followed by High-Dose Melphalan (HDM) and Maintenance with Bortezomib or Thalidomide In Patients with Newly Diagnosed Multiple Myeloma (MM)

Pieter Sonneveld, Ingo Schmidt-Wolf, Bronno van der Holt, Laila el Jarari, Uta Bertsch, Hans Salwender, Sonja Zweegman, Edo Vellenga, Joerg Schubert, Igor Wolfgang Blau, Asiong Jie, Berna Beverloo, Dirk Hose, Anna Jauch, Helgi van de Velde, Martijn Schaafsma, Walter Lindemann, Marie Jose Kersten, Ulrich Duehrsen, MD, Michel Delforge, Katja Weisel, Sandra Croockewit, Hans Martin, Shulamit Wittebol, Christof Scheid, Gerard Bos, Marinus van Marwijk-Kooy, Pierre Wijermans, Henk Lokhorst, Hartmut Goldschmidt
Journal: Blood
Blood (2010) 116 (21): 40.
https://doi.org/10.1182/blood.V116.21.40.40
Published: 2010
Journal Articles

Prognostic Impact of Genetic Subgroups and Development of Gene Classifiers for Response, PFS and OS In Multiple Myeloma Patients Treated with Bortezomib or Conventional Agents In HOVON65/GMMG-HD4 Trial

Annemiek Broyl, MD, Rowan Kuiper, Martin H. van Vliet, PhD, Erik H. van Beers, PhD, Yvonne de Knegt, Bronno van der Holt, PhD, Laila el Jarari, Berna Beverloo, PhD, H. Lokhorst, Sonja Zweegman, George Mulligan, PhD, Hartmut Goldschmidt, Mark van Duin, PhD, Pieter Sonneveld
Journal: Blood
Blood (2010) 116 (21): 445.
https://doi.org/10.1182/blood.V116.21.445.445
Published: 2010
Journal Articles

Influence of Renal Function on Outcome of VAD or Bortezomib, Doxorubicin, Dexamethasone (PAD) Induction Treatment Followed by High-Dose Melphalan (HDM): A Subgroup Analysis From the HOVON-65/GMMG-HD4 Randomized Phase III Trial for Newly Diagnosed Multiple Myeloma

Christof Scheid, Pieter Sonneveld, Ingo Schmidt-Wolf, Bronno van der Holt, Thomas Hielscher, Laila el Jarari, Uta Bertsch, Hans Salwender, Sonja Zweegman, Mathias Hänel, Edo Vellenga, Joerg Schubert, Igor Wolfgang Blau, Asiong Jie, Helgi Van de elde, Norma Peter, Martijn Schaafsma, Walter Lindemann, Marie Jose Kersten, Ulrich Duehrsen, Michel Delforge, Katja Weisel, Sandra Croockewit, Hans Martin, Shulamit Wittebol, Harry Schouten, Marinus van Marwijk-Kooy, Pierre Wijermans, Henk M Lokhorst, Hartmut Goldschmidt
Journal: Blood
Blood (2010) 116 (21): 2396.
https://doi.org/10.1182/blood.V116.21.2396.2396
Published: 2010
Journal Articles

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

Clinical Trials & Observations
Annemiek Broyl, Dirk Hose, Henk Lokhorst, Yvonne de Knegt, Justine Peeters, Anna Jauch, Uta Bertsch, Arjan Buijs, Marian Stevens-Kroef, H. Berna Beverloo, Edo Vellenga, Sonja Zweegman, Marie-Josée Kersten, Bronno van der Holt, Laila el Jarari, George Mulligan, Hartmut Goldschmidt, Mark van Duin, Pieter Sonneveld
Journal: Blood
Blood (2010) 116 (14): 2543–2553.
https://doi.org/10.1182/blood-2009-12-261032
Published: 2010
Includes: Supplemental data
Journal Articles

Successful Harvesting of Peripheral Hematopoietic Stem Cells after Induction Treatment with Bortezomib, Adriamycin, Dexamethasone (PAD) in Patients with Newly Diagnosed Multiple Myeloma (MM)

Hartmut Goldschmidt, Henk M. Lokhorst, Uta Bertsch, Bronno van der Holt, Laila el Jarari, Hans-Jürgen Salwender, Sonja Zweegman, Edo Vellenga, Jörg Schubert, Igor W. Blau, Asiong Jie, Berna Beverloo, Dirk Hose, Helgi van de Velde, Martyn Ronald Schaafsma, Marie Jose Kersten, Michel Delforge, Okke de Weerdt, Rene Van der Griend, Pierre Wijermans, Hans Martin, Christof Scheid, Mathias Hänel, Ingo G.H. Schmidt-Wolf, Pieter Sonneveld for the HOVON GMMG group
Journal: Blood
Blood (2008) 112 (11): 3470.
https://doi.org/10.1182/blood.V112.11.3470.3470
Published: 2008