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Energy balance and fitness in adult survivors of childhood acute lymphoblastic leukemia
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
IgH-V(D)J NGS-MRD measurement pre- and early post-allotransplant defines very low- and very high-risk ALL patients
Issue Archive
Table of Contents
INSIDE BLOOD COMMENTARIES
PLENARY PAPER
THROMBOSIS AND HEMOSTASIS
Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor
Yaozu Xiang,Jijun Cheng,Dandan Wang,Xiaoyue Hu,Yi Xie,Jeremiah Stitham,Gourg Atteya,Jing Du,Wai Ho Tang,Seung Hee Lee,Kristen Leslie,Geralyn Spollett,Zejian Liu,Erica Herzog,Raimund I. Herzog,Jun Lu,Kathleen A. Martin,John Hwa
BLOOD SPOTLIGHT
REVIEW ARTICLE
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Energy balance and fitness in adult survivors of childhood acute lymphoblastic leukemia
Clinical Trials & Observations
Kirsten K. Ness,James P. DeLany,Sue C. Kaste,Daniel A. Mulrooney,Ching-Hon Pui,Wassim Chemaitilly,Robyn E. Karlage,Jennifer Q. Lanctot,Carrie R. Howell,Lu Lu,Deo Kumar Srivastava,Leslie L. Robison,Melissa M. Hudson
LYMPHOID NEOPLASIA
Central nervous system acute lymphoblastic leukemia: role of natural killer cells
Liron Frishman-Levy,Avishai Shemesh,Allan Bar-Sinai,Chao Ma,Zhenya Ni,Shahar Frenkel,Vera Muench,Hilke Bruckmueller,Christian Vokuhl,Klaus-Michael Debatin,Cornelia Eckert,Martin Stanulla,Martin Schrappe,Kerry S. Campbell,Ron Loewenthal,Denis M. Schewe,Jacob Hochman,Lueder H. Meyer,Dan Kaufman,Gunnar Cario,Angel Porgador,Shai Izraeli
MYELOID NEOPLASIA
Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2
Takeshi Ueda,Akiko Nagamachi,Keiyo Takubo,Norimasa Yamasaki,Hirotaka Matsui,Akinori Kanai,Yuichiro Nakata,Kenichiro Ikeda,Takaaki Konuma,Hideaki Oda,Linda Wolff,Zen-ichiro Honda,Xudong Wu,Kristian Helin,Atsushi Iwama,Toshio Suda,Toshiya Inaba,Hiroaki Honda
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
Clinical Trials & Observations
Hiba El Hajj,Zeina Dassouki,Caroline Berthier,Emmanuel Raffoux,Lionel Ades,Olivier Legrand,Rita Hleihel,Umut Sahin,Nadim Tawil,Ala Salameh,Kazem Zibara,Nadine Darwiche,Mohamad Mohty,Hervé Dombret,Pierre Fenaux,Hugues de Thé,Ali Bazarbachi
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
Maria Paola Martelli,Ilaria Gionfriddo,Federica Mezzasoma,Francesca Milano,Sara Pierangeli,Floriana Mulas,Roberta Pacini,Alessia Tabarrini,Valentina Pettirossi,Roberta Rossi,Calogero Vetro,Lorenzo Brunetti,Paolo Sportoletti,Enrico Tiacci,Francesco Di Raimondo,Brunangelo Falini
THROMBOSIS AND HEMOSTASIS
Structural and functional characterization of a specific antidote for ticagrelor
Andrew Buchanan,Philip Newton,Susanne Pehrsson,Tord Inghardt,Thomas Antonsson,Peder Svensson,Tove Sjögren,Linda Öster,Annika Janefeldt,Ann-Sofie Sandinge,Feenagh Keyes,Mark Austin,Jennifer Spooner,Peter Gennemark,Mark Penney,Garnet Howells,Tristan Vaughan,Sven Nylander
TRANSPLANTATION
IgH-V(D)J NGS-MRD measurement pre- and early post-allotransplant defines very low- and very high-risk ALL patients
Clinical Trials & Observations
Michael A. Pulsipher,Chris Carlson,Bryan Langholz,Donna A. Wall,Kirk R. Schultz,Nancy Bunin,Ilan Kirsch,Julie M. Gastier-Foster,Michael Borowitz,Cindy Desmarais,David Williamson,Michael Kalos,Stephan A. Grupp
VASCULAR BIOLOGY
BLOOD WORK
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Cover Image
Cover Image
![issue cover]()
A three-dimensional rendering of a forming Weibel-Palade body (green) that is connected to the Golgi apparatus (yellow) via various connections. Weibel-Palade bodies are formed by vascular endothelial cells and are filled with large quantities of von Willebrand factor. The multiple connections between forming Weibel-Palade bodies and the Golgi apparatus were discovered by performing correlative light and electron microscopy and electron tomography on green fluorescent protein–labeled Weibel-Palade bodies. The connections seem to facilitate content delivery to newly forming Weibel-Palade bodies. See the article by Mourik et al on page 3509.
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