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Journal Articles

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Blood (2018) 131 (22): 2454–2465.

https://doi.org/10.1182/blood-2017-11-814913

Published: 2018

Includes: Supplemental data

Journal Articles

Arsenic trioxide and all- trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1 -mutated AML cells

Maria Paola Martelli, Ilaria Gionfriddo, Federica Mezzasoma, Francesca Milano, Sara Pierangeli, Floriana Mulas, Roberta Pacini, Alessia Tabarrini, Valentina Pettirossi, Roberta Rossi, Calogero Vetro, Lorenzo Brunetti, Paolo Sportoletti, Enrico Tiacci, Francesco Di Raimondo, Brunangelo Falini

Blood (2015) 125 (22): 3455–3465.

https://doi.org/10.1182/blood-2014-11-611459

Published: 2015

Includes: Supplemental data

Journal Articles

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity

Valentina Pettirossi, Alessia Santi, Elisa Imperi, Guido Russo, Alessandra Pucciarini, Barbara Bigerna, Gianluca Schiavoni, Elisabetta Fortini, Ariele Spanhol-Rosseto, Paolo Sportoletti, Roberta Mannucci, Maria Paola Martelli, Ludger Klein-Hitpass, Brunangelo Falini, Enrico Tiacci

Blood (2015) 125 (8): 1207–1216.

https://doi.org/10.1182/blood-2014-10-603100

Published: 2015

Includes: Supplemental data

Journal Articles

Targeting The BRAF-MEK-ERK Pathway In Hairy Cell Leukemia

Valentina Pettirossi, Alessia Santi, Guido Russo, Alessandra Pucciarini, Barbara Bigerna, Elisabetta Fortini, Elisa Imperi, Roberta Mannucci, Ildo Nicoletti, Maria Paola Martelli, Enrico Tiacci, Brunangelo Falini

Blood (2013) 122 (21): 3064.

https://doi.org/10.1182/blood.V122.21.3064.3064

Published: 2013

Journal Articles

Constant Activation of the RAF-MEK-ERK Pathway As a Diagnostic and Therapeutic Target in Hairy Cell Leukemia.

Enrico Tiacci, Gianluca Schiavoni, Maria Paola Martelli, Emanuela Boveri, Roberta Pacini, Alessia Tabarrini, Silvia Zibellini, Alessia Santi, Valentina Pettirossi, Elisabetta Fortini, Stefano Ascani, Luca Arcaini, Giorgio Inghirami, Marco Paulli, Brunangelo Falini

Blood (2012) 120 (21): 2657.

https://doi.org/10.1182/blood.V120.21.2657.2657

Published: 2012

Journal Articles

Absence of BRAF -V600E in the human cell lines BONNA-12, ESKOL, HAIR-M, and HC-1 questions their origin from hairy cell leukemia

Enrico Tiacci, Alessandra Pucciarini, Barbara Bigerna, Valentina Pettirossi, Francesca Strozzini, Maria Paola Martelli, Alessia Tabarrini, Hans G. Drexler, Brunangelo Falini

Blood (2012) 119 (22): 5332–5333.

https://doi.org/10.1182/blood-2011-12-400374

Published: 2012

Journal Articles

Histone Deacetylase Inhibitors Induce Cell Growth Inhibition and Apoptosis in NPM1 -Mutated AML Cells: A Possible Role for Epigenetic Therapies in AML Carrying NPM1 Gene Mutations

Ilaria Gionfriddo, Federica Mezzasoma, Federica Cecchetti, Roberta Rossi, Francesca Strozzini, Francesco Di Raimondo, MD, Valentina Pettirossi, PhD, Brunangelo Falini, MD, Maria Paola Martelli, MD

Blood (2011) 118 (21): 2621.

https://doi.org/10.1182/blood.V118.21.2621.2621

Published: 2011

Journal Articles

CD34 + cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

Blood (2010) 116 (19): 3907–3922.

https://doi.org/10.1182/blood-2009-08-238899

Published: 2010

Includes: Supplemental data

Journal Articles

Dissecting the Hierarchical Level of Hematopoietic Progenitors' Involvement in AML with NPM1 Gene Mutation and Their Engraftment Potential in Immunocompromised Mice.

Blood (2009) 114 (22): 480.

https://doi.org/10.1182/blood.V114.22.480.480

Published: 2009

Journal Articles

Acute Myeloid Leukemia with Mutated NPM1 Presenting with Life-Threatening, Either Arterial or Venous, Thromboembolism: a Report of 4 Cases.

Maria Paola Martelli, Lorenzo Brunetti, Luca De Carolis, Elisabetta Agliani, Laura Berchicci, Elisabetta Bonifacio, Valentina Pettirossi, Ilaria Gionfriddo, Debora Cecchini, Alessia Tabarrini, Roberta Rossi, Stelvio Ballanti, Massimo F Martelli, Brunangelo Falini

Blood (2009) 114 (22): 4135.

https://doi.org/10.1182/blood.V114.22.4135.4135

Published: 2009

Journal Articles

Evidence for CD34+ Hematopoietic Progenitor Cell Involvement in Acute Myeloid Leukemia with NPM1 Gene Mutation: Implications for the Cell of Origin

Maria Paola Martelli, Valentina Pettirossi, Elisabetta Bonifacio, Federica Mezzasoma, Nicla Manes, Debora Cecchini, Maruska Capanni, Ilaria Gionfriddo, Arcangelo Liso, Roberta Pacini, Manola Carini, Giorgina Specchia, Massimo F Martelli, Brunangelo Falini

Blood (2008) 112 (11): 307.

https://doi.org/10.1182/blood.V112.11.307.307

Published: 2008

Journal Articles

Reciprocal Interaction between NPM Leukemic Mutants and Arf: Structural Basis and Functional Consequences.

Niccolo’ Bolli, Maria Paola Martelli, Barbara Bigerna, Alessandra Pucciarini, Barbara Verducci, Teresa Pallotta, Felicetta de Marco, Valentina Pettirossi, Roberta Mannucci, Elisabetta Bonifacio, Antonio Tabilio, Ildo Nicoletti, Brunangelo Falini

Blood (2006) 108 (11): 1939.

https://doi.org/10.1182/blood.V108.11.1939.1939

Published: 2006

Journal Articles

Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca 2+ -dependent association with annexin VI

Blood (2005) 105 (7): 2812–2820.

https://doi.org/10.1182/blood-2004-07-2630

Published: 2005

Journal Articles

Tumor Protein D52 (TPD52): A Novel B Cell/Plasma Cell Molecule Identified through a Proteomic Approach and Characterized by Unique Expression Pattern and Ca 2+ -Dependent Association with Annexin VI.

Enrico Tiacci, Pier-Luigi Orvietani, Barbara Bigerna, Alessandra Pucciarini, Roberta Pacini, Garry Corthals, Valentina Pettirossi, Maria Paola Martelli, Arcangelo Liso, Niccolo Bolli, Alessia Tabarrini, Federica Frenguelli, Roberta Benedetti, Stefano Pileri, Jennyfer A. Byrne, Brunangelo Falini

Blood (2004) 104 (11): 3652.

https://doi.org/10.1182/blood.V104.11.3652.3652

Published: 2004

NARROW

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Arsenic trioxide and all- trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1 -mutated AML cells

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity

Targeting The BRAF-MEK-ERK Pathway In Hairy Cell Leukemia

Constant Activation of the RAF-MEK-ERK Pathway As a Diagnostic and Therapeutic Target in Hairy Cell Leukemia.

Absence of BRAF -V600E in the human cell lines BONNA-12, ESKOL, HAIR-M, and HC-1 questions their origin from hairy cell leukemia

Histone Deacetylase Inhibitors Induce Cell Growth Inhibition and Apoptosis in NPM1 -Mutated AML Cells: A Possible Role for Epigenetic Therapies in AML Carrying NPM1 Gene Mutations

CD34 + cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

Dissecting the Hierarchical Level of Hematopoietic Progenitors' Involvement in AML with NPM1 Gene Mutation and Their Engraftment Potential in Immunocompromised Mice.

Acute Myeloid Leukemia with Mutated NPM1 Presenting with Life-Threatening, Either Arterial or Venous, Thromboembolism: a Report of 4 Cases.

Evidence for CD34+ Hematopoietic Progenitor Cell Involvement in Acute Myeloid Leukemia with NPM1 Gene Mutation: Implications for the Cell of Origin

Reciprocal Interaction between NPM Leukemic Mutants and Arf: Structural Basis and Functional Consequences.

Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca 2+ -dependent association with annexin VI

Tumor Protein D52 (TPD52): A Novel B Cell/Plasma Cell Molecule Identified through a Proteomic Approach and Characterized by Unique Expression Pattern and Ca 2+ -Dependent Association with Annexin VI.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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