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Issue Archive

Volume 124, Issue 8
August 21 2014
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Envelope, please. And the award goes to…
Donald B. Kohn,Roger P. Hollis
View Articletitled, Envelope, please. And the award goes to…
INSIDE BLOOD COMMENTARY
Hematopoietic ontogeny in the axolotl
David L. Stachura,David Traver
View Articletitled, Hematopoietic ontogeny in the axolotl
INSIDE BLOOD COMMENTARY
Asparaginase allergies: it’s all in the genes
Clinical Trials & Observations
Meir Wetzler
View Articletitled, Asparaginase allergies: it’s all in the genes
INSIDE BLOOD COMMENTARY
How to treat old MCL patients: one size fits it all?
Martin Dreyling,on behalf of the European Mantle Cell Lymphoma Network,Simone Ferrero,on behalf of the European Mantle Cell Lymphoma Network
View Articletitled, How to treat old MCL patients: one size fits it all?
INSIDE BLOOD COMMENTARY
Solitary bone plasmacytomas need to flow
Meletios A. Dimopoulos,Evangelos Terpos
View Articletitled, Solitary bone plasmacytomas need to flow
INSIDE BLOOD COMMENTARY
fHLH: becoming a blended family
Carl E. Allen,Kenneth L. McClain
View Articletitled, fHLH: becoming a blended family
INSIDE BLOOD COMMENTARY
How mutant HFE causes hereditary hemochromatosis
Martina U. Muckenthaler
View Articletitled, How mutant HFE causes hereditary hemochromatosis
INSIDE BLOOD COMMENTARY
Factor XIII and adipocyte biology
Deane F. Mosher
View Articletitled, Factor XIII and adipocyte biology
INSIDE BLOOD COMMENTARY
VKORC1 ER mislocalization causes rare disease
Wade D. Van Horn
View Articletitled, VKORC1 ER mislocalization causes rare disease
INSIDE BLOOD COMMENTARY
FFS: an end(point) to our problems in chronic GVHD trials?
David A. Jacobsohn
View Articletitled, FFS: an end(point) to our problems in chronic GVHD trials?

BLOOD WORK

A plasma cell ribbon
Armin Rashidi,Stephen I. Fisher
View Articletitled, A plasma cell ribbon
Schistosomal eggs identified on bone marrow biopsy
Catherine Jones,Temekka V. Leday
View Articletitled, Schistosomal eggs identified on bone marrow biopsy

PLENARY PAPER

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs
Anais Girard-Gagnepain,Fouzia Amirache,Caroline Costa,Camille Lévy,Cecilia Frecha,Floriane Fusil,Didier Nègre,Dimitri Lavillette,François-Loïc Cosset,Els Verhoeyen
View Articletitled, Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs
Supplemental data

PLENARY PAPER

Mapping hematopoiesis in a fully regenerative vertebrate: the axolotl
David Lopez,Li Lin,James R. Monaghan,Christopher R. Cogle,Frank J. Bova,Malcolm Maden,Edward W. Scott
View Articletitled, Mapping hematopoiesis in a fully regenerative vertebrate: the axolotl
Supplemental data

REVIEW ARTICLE

Genetic polymorphisms of vein wall remodeling in chronic venous disease: a narrative and systematic review
Vighnesh Bharath,Susan R. Kahn,Alejandro Lazo-Langner
View Articletitled, Genetic polymorphisms of vein wall remodeling in chronic venous disease: a narrative and systematic review

HOW I TREAT

How we evaluate and treat neutropenia in adults
CME Clinical Trials & Observations
Christopher Gibson,Nancy Berliner
View Articletitled, How we evaluate and treat neutropenia in adults

CLINICAL TRIALS AND OBSERVATIONS

Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma
Clinical Trials & Observations
Paul M. Barr,Thomas P. Miller,Jonathan W. Friedberg,Derick R. Peterson,Andrea M. Baran,Megan Herr,Catherine M. Spier,Haiyan Cui,Denise J. Roe,Daniel O. Persky,Carla Casulo,Jamie Littleton,Mark Schwartz,Soham Puvvada,Terry H. Landowski,Lisa M. Rimsza,Robert T. Dorr,Richard I. Fisher,Steven H. Bernstein,Margaret M. Briehl
View Articletitled, Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma
HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies
Clinical Trials & Observations
Christian A. Fernandez,Colton Smith,Wenjian Yang,Mihir Daté,Donald Bashford,Eric Larsen,W. Paul Bowman,Chengcheng Liu,Laura B. Ramsey,Tamara Chang,Victoria Turner,Mignon L. Loh,Elizabeth A. Raetz,Naomi J. Winick,Stephen P. Hunger,William L. Carroll,Suna Onengut-Gumuscu,Wei-Min Chen,Patrick Concannon,Stephen S. Rich,Paul Scheet,Sima Jeha,Ching-Hon Pui,William E. Evans,Meenakshi Devidas,Mary V. Relling
View Articletitled, <em>HLA-DRB1</em>*07:01 is associated with a higher risk of asparaginase allergies
Supplemental data

IMMUNOBIOLOGY

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy
Brian Philip,Evangelia Kokalaki,Leila Mekkaoui,Simon Thomas,Karin Straathof,Barry Flutter,Virna Marin,Teresa Marafioti,Ronjon Chakraverty,David Linch,Sergio A. Quezada,Karl S. Peggs,Martin Pule
View Articletitled, A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy
Supplemental data

LYMPHOID NEOPLASIA

Real world data on primary treatment for mantle cell lymphoma: a Nordic Lymphoma Group observational study
Clinical Trials & Observations
Anna Abrahamsson,Alexandra Albertsson-Lindblad,Peter N. Brown,Stefanie Baumgartner-Wennerholm,Lars M. Pedersen,Francesco D’Amore,Herman Nilsson-Ehle,Paw Jensen,Michael Pedersen,Christian H. Geisler,Mats Jerkeman
View Articletitled, Real world data on primary treatment for mantle cell lymphoma: a Nordic Lymphoma Group observational study
Supplemental data
Outcome prediction in plasmacytoma of bone: a risk model utilizing bone marrow flow cytometry and light-chain analysis
Clinical Trials & Observations Brief Report
Quentin A. Hill,Andy C. Rawstron,Ruth M. de Tute,Roger G. Owen
View Articletitled, Outcome prediction in plasmacytoma of bone: a risk model utilizing bone marrow flow cytometry and light-chain analysis
Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma
Clinical Trials & Observations Brief Report
Bruno Paiva,Mauricio Chandia,Maria-Belen Vidriales,Enrique Colado,Teresa Caballero-Velázquez,Fernando Escalante,Alfonso Garcia de Coca,Maria-Carmen Montes,Ramon Garcia-Sanz,Enrique M. Ocio,Maria-Victoria Mateos,Jesus F. San Miguel
View Articletitled, Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma
Supplemental data

MYELOID NEOPLASIA

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis
Tobias Herold,Klaus H. Metzeler,Sebastian Vosberg,Luise Hartmann,Christoph Röllig,Friedrich Stölzel,Stephanie Schneider,Max Hubmann,Evelyn Zellmeier,Bianka Ksienzyk,Vindi Jurinovic,Zlatana Pasalic,Purvi M. Kakadia,Annika Dufour,Alexander Graf,Stefan Krebs,Helmut Blum,Maria Cristina Sauerland,Thomas Büchner,Wolfgang E. Berdel,Bernhard J. Woermann,Martin Bornhäuser,Gerhard Ehninger,Ulrich Mansmann,Wolfgang Hiddemann,Stefan K. Bohlander,Karsten Spiekermann,Philipp A. Greif
View Articletitled, Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis
Supplemental data
Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup
Clinical Trials & Observations
Marie-Anne Hospital,Thomas Prebet,Sarah Bertoli,Xavier Thomas,Emmanuelle Tavernier,Thorsten Braun,Cécile Pautas,Aurore Perrot,Bruno Lioure,Philippe Rousselot,Jérôme Tamburini,Thomas Cluzeau,Johanna Konopacki,Edouard Randriamalala,Céline Berthon,Marie-Pierre Gourin,Christian Recher,Jean-Yves Cahn,Norbert Ifrah,Hervé Dombret,Nicolas Boissel
View Articletitled, Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

miR-142-3p acts as an essential modulator of neutrophil development in zebrafish
Hong-Bo Fan,Yi-Jie Liu,Lei Wang,Ting-Ting Du,Mei Dong,Li Gao,Zhao-Zheng Meng,Yi Jin,Yi Chen,Min Deng,Huang-Tian Yang,Qing Jing,Ai-Hua Gu,Ting-Xi Liu,Yong Zhou
View Articletitled, miR-142-3p acts as an essential modulator of neutrophil development in zebrafish
Supplemental data
Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis
Clinical Trials & Observations Brief Report
Kejian Zhang,Shanmuganathan Chandrakasan,Heather Chapman,C. Alexander Valencia,Ammar Husami,Diane Kissell,Judith A. Johnson,Alexandra H. Filipovich
View Articletitled, Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

RED CELLS, IRON, AND ERYTHROPOIESIS

HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
Xing-gang Wu,Yang Wang,Qian Wu,Wai-Hang Cheng,Wenjing Liu,Yueshui Zhao,Claire Mayeur,Paul J. Schmidt,Paul B. Yu,Fudi Wang,Yin Xia
View Articletitled, HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
Supplemental data

THROMBOSIS AND HEMOSTASIS

Factor XIII-A transglutaminase acts as a switch between preadipocyte proliferation and differentiation
Vamsee D. Myneni,Kiyotaka Hitomi,Mari T. Kaartinen
View Articletitled, Factor XIII-A transglutaminase acts as a switch between preadipocyte proliferation and differentiation
Supplemental data
The Arg98Trp mutation in human VKORC1 causing VKCFD2 disrupts a di-arginine–based ER retention motif
Katrin J. Czogalla,Arijit Biswas,Simone Rost,Matthias Watzka,Johannes Oldenburg
View Articletitled, The Arg98Trp mutation in human VKORC1 causing VKCFD2 disrupts a di-arginine–based ER retention motif
Supplemental data

TRANSPLANTATION

Failure-free survival after initial systemic treatment of chronic graft-versus-host disease
Yoshihiro Inamoto,Mary E. D. Flowers,Brenda M. Sandmaier,Sahika Z. Aki,Paul A. Carpenter,Stephanie J. Lee,Barry E. Storer,Paul J. Martin
View Articletitled, Failure-free survival after initial systemic treatment of chronic graft-versus-host disease
Supplemental data
Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT
Clinical Trials & Observations
Corey Cutler,Brent Logan,Ryotaro Nakamura,Laura Johnston,Sung Choi,David Porter,William J. Hogan,Marcelo Pasquini,Margaret L. MacMillan,Jack W. Hsu,Edmund K. Waller,Stephan Grupp,Philip McCarthy,Juan Wu,Zhen-Huan Hu,Shelly L. Carter,Mary M. Horowitz,Joseph H. Antin
View Articletitled, Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Neutropenia in adults
CME
View Articletitled, Neutropenia in adults
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