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Journal Articles

Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature

Sayantanee Dutta, Paul Kerbs, Maja Rothenberg-Thurley, Bianka Ksienzyk, Stefan Krebs, Helmut Blum, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold, Sebastian Vosberg, Philipp A. Greif

Blood (2022) 140 (Supplement 1): 8912–8913.

https://doi.org/10.1182/blood-2022-168939

Published: 2022

Journal Articles

ARID1A Controls a Novel Transcriptional Network Regulating FAS in Follicular Lymphoma

Martina Antoniolli, Maria Solovey, Deepak Bararia, Carolin Dorothea Strobl, William David Keay, Johannes Adrian Hildebrand, Michael Heide, Verena Passerini, Lucas Wange, Wolfgang Enard, Susanne Thieme, Helmut Blum, Martina Rudelius, Sebastian Bultmann, Heinrich Leonhardt, Marion Subklewe, Michael von Bergwelt, Maria Colomé-Tatché, Oliver Weigert

Blood (2021) 138 (Supplement 1): 3492.

https://doi.org/10.1182/blood-2021-148862

Published: 2021

Journal Articles

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, MD, Sebastian Vosberg, Bianka Ksienzyk, Sebastian Tschuri, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, Dr., Stephanie Schneider, PhD, Martin Neumann, Claudia D. Baldus, MD, Christian Thiede, MD, Jan Moritz Middeke, MD, Friedrich Stoelzel, Stefan K. Bohlander, MD, Karsten Spiekermann, MD, Wolfgang Hiddemann, PhD, Klaus H. Metzeler, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2018-99-115881

Published: 2018

Journal Articles

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells

Laura Bernhardine Kuhn, MSc, Stefanie Zapf, Dr., Djermanovic Kristina, Dr., Daniel C. Strobl, BSc., Falk Weih, Dr., Helmut Blum, Dr., Oliver Weigert, MD, Lothar J. Strobl, Dr., Zimber-Strobl Ursula, Dr.

Blood (2018) 132 (Supplement 1): 1340.

https://doi.org/10.1182/blood-2018-99-113793

Published: 2018

Journal Articles

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 2713.

https://doi.org/10.1182/blood.V130.Suppl_1.2713.2713

Published: 2017

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

PS29MRC - a Novel Predictive Score for Response to Therapy in Acute Myeloid Leukemia

Blood (2016) 128 (22): 1209.

https://doi.org/10.1182/blood.V128.22.1209.1209

Published: 2016

Journal Articles

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Blood (2016) 128 (22): 288.

https://doi.org/10.1182/blood.V128.22.288.288

Published: 2016

Journal Articles

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Blood (2016) 128 (9): 1246–1259.

https://doi.org/10.1182/blood-2015-11-679167

Published: 2016

Includes: Supplemental data

Journal Articles

Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL

Lorenz Bastian, Martin Neumann, MD, Nicola Gökbuget, MD, Cornelia Schlee, Jutta Ortiz Tanchez, Sebastian Vosberg, Alva Rani James, Michael P Schroeder, Stefan Schwartz, MD, Dieter Hoelzer, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Jochen Hecht, Monika Brüggemann, Philipp A. Greif, Claudia D. Baldus, MD PhD

Blood (2015) 126 (23): 2625.

https://doi.org/10.1182/blood.V126.23.2625.2625

Published: 2015

Journal Articles

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Sebastian Vosberg, Luise Hartmann, MSc, Stephanie Schneider, PhD, Klaus H. Metzeler, MD, Bianka Ksienzyk, Kathrin Bräundl, Martin Neumann, MD, Claudia D Baldus, MD, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Karsten Spiekermann, MD, Stefan K. Bohlander, MD, Ulrich Mansmann, PhD, Philipp A. Greif, MD

Blood (2015) 126 (23): 3859.

https://doi.org/10.1182/blood.V126.23.3859.3859

Published: 2015

Journal Articles

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

Martin Neumann, MD, Sebastian Vosberg, Eva Kristin Von Der Heide, BSc, Cornelia Schlee, Jutta Ortiz Tanchez, Konstandina Isaakidis, Liliana H. Mochmann, BS,MSc, Lars R. Fransecky, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Philipp A. Greif, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 3843.

https://doi.org/10.1182/blood.V126.23.3843.3843

Published: 2015

Journal Articles

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Luise Hartmann, MSc, Sebastian Vosberg, Klaus H. Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, PhD, Stephanie Schneider, PhD, Stefan Krebs, PhD, Alexander Graf, PhD, Helmut Blum, PhD, Martin Neumann, MD, Claudia D Baldus, MD, Stefan K. Bohlander, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2015) 126 (23): 690.

https://doi.org/10.1182/blood.V126.23.690.690

Published: 2015

Journal Articles

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

Patricia Silva, Martin Neumann, MD, Sebastian Vosberg, Cornelia Schlee, Konstandina Isaakidis, Michael P Schroeder, Jutta Ortiz-Tánchez, Lars R. Fransecky, Teresa Hartung, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Gerhard Ehninger, Hubert Serve, MD, Wolfgang E Berdel, MD, Philipp A. Greif, Christoph Röllig, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 804.

https://doi.org/10.1182/blood.V126.23.804.804

Published: 2015

Journal Articles

Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression

Blood (2014) 124 (21): 4604.

https://doi.org/10.1182/blood.V124.21.4604.4604

Published: 2014

Journal Articles

The Mutatome of CBFB / MYH11- rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, Klaus H Metzeler, MD, Tobias Herold, MD, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Nikola P Konstandin, Christine Wang, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Stephanie Schneider, PhD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Philipp A Greif, MD

Blood (2014) 124 (21): 14.

https://doi.org/10.1182/blood.V124.21.14.14

Published: 2014

Journal Articles

Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model

Sayantanee Dutta, Alexandre Krause, Sebastian Vosberg, Tobias Herold, MD, Bianca Ksienzyk, Leticia Quintanilla-Fend, Belay Tizazu, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Philipp A Greif, MD, Marlon Schneider, Maik Dahlhof, Karsten Spiekermann, MD, Ursula Zimber-Strobl, Eckhard Wolf, Stefan K Bohlander, MD

Blood (2014) 124 (21): 126.

https://doi.org/10.1182/blood.V124.21.126.126

Published: 2014

Journal Articles

Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion

Sebastian Vosberg, Tobias Herold, MD, Klaus H Metzeler, MD, Stephanie Schneider, PhD, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Ulrich Mansmann, PhD, Philipp A Greif, MD

Blood (2014) 124 (21): 1058.

https://doi.org/10.1182/blood.V124.21.1058.1058

Published: 2014

Journal Articles

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases

Blood (2014) 124 (21): 17.

https://doi.org/10.1182/blood.V124.21.17.17

Published: 2014

Journal Articles

Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients

Eva von der Heide, Sebastian Vosberg, Martin Neumann, MD, Liliana H. Mochmann, MS, Alva Rani James, Jutta Ortiz Tanchez, Cornelia Schlee, MS, Konstandina Isaakidis, Marlene Luther, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Wolf-Karsten Hofmann, Philipp A Greif, MD, Claudia D Baldus, MD

Blood (2014) 124 (21): 699.

https://doi.org/10.1182/blood.V124.21.699.699

Published: 2014

NARROW

Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature

ARID1A Controls a Novel Transcriptional Network Regulating FAS in Follicular Lymphoma

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

PS29MRC - a Novel Predictive Score for Response to Therapy in Acute Myeloid Leukemia

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression

The Mutatome of CBFB / MYH11- rearranged Acute Myeloid Leukemia (AML)

Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model

Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases

Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients

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American Society of Hematology

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American Society of Hematology

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