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Journal Articles

Efficacy and Safety of Bemcentinib in Patients with Myelodysplastic Syndromes or Acute Myeloid Leukemia Failing Hypomethylating Agents

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-140240

Published: 2020

Journal Articles

Development and Exploitation of a Fully Human and Modular Organotypic Bone Marrow Niche Model to Study the Role of Stroma-Produced Factors in Human MDS

Alexander Schaeffer, Ewelina Czlonka, Irene Tirado-González, Thomas Böse, Jennifer Beauvarlet, Ivan Kur, Aline Bözec, Halvard Bönig, Christian H. Brandts, MD, Uwe Platzbecker, Katharina S. Götze, Hind Medyouf

Blood (2020) 136 (Supplement 1): 23.

https://doi.org/10.1182/blood-2020-142782

Published: 2020

Journal Articles

The microenvironment in human myeloid malignancies: emerging concepts and therapeutic implications

Hind Medyouf

Blood (2017) 129 (12): 1617–1626.

https://doi.org/10.1182/blood-2016-11-696070

Published: 2017

Journal Articles

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Blood (2016) 128 (9): 1246–1259.

https://doi.org/10.1182/blood-2015-11-679167

Published: 2016

Includes: Supplemental data

Journal Articles

Development of a DNA-Based Targeted Assay Suitable for Accurate Quantification of Chromosomal Deletions in Myelodysplastic Syndromes with Deletion (5q) and Other Clonal Diseases

Johann-Christoph Jann, Daniel Nowak, Florian Nolte, Stephanie Fey, Verena Nowak, Julia Obländer, Jovita Pressler, Alice Fabarius, PhD, Claudia Haferlach, MD, Hind Medyouf, PhD, Wolf-Karsten Hofmann, Maximilian Mossner

Blood (2014) 124 (21): 1925.

https://doi.org/10.1182/blood.V124.21.1925.1925

Published: 2014

Journal Articles

Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression

Blood (2014) 124 (21): 4604.

https://doi.org/10.1182/blood.V124.21.4604.4604

Published: 2014

Journal Articles

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

Armin Ehninger, Tobias Boch, Hind Medyouf, Katja Müdder, Gertraud Orend, Andreas Trumpp

Blood (2014) 123 (26): 4054–4063.

https://doi.org/10.1182/blood-2013-10-533711

Published: 2014

Includes: Supplemental data

Journal Articles

Next Generation Sequencing-Based Molecular Dissection Of Lineage-Specific Mutational Hierarchies In Oligoclonal Primary and Xenografted Myelodysplasia

Johann-Christoph Jann, Daniel Nowak, MD, Florian Nolte, MD, Claudia Haferlach, MD, Marita Staller, Verena Nowak, Bettina Zens, Katja Müdder, Corinna Klein, Julia Obländer, Stephanie Fey, Jovita Vogler, Alice Fabarius, PhD, Alexander Kohlmann, PhD, Wolf-Karsten Hofmann, MD, Andreas Trumpp, PhD, Hind Medyouf, PhD, Maximilian Mossner

Blood (2013) 122 (21): 519.

https://doi.org/10.1182/blood.V122.21.519.519

Published: 2013

Journal Articles

Significant Engraftment of Immature Hematopoietic Cells From Patients with Low Risk Myelodysplastic Syndromes (MDS) in Immunodeficient Mice

Hind Medyouf, PhD, Florian Nolte, MD, Maximilian Mossner, Verena Nowak, Bettina Zens, Katja Müdder, Julia Obländer, Stephanie Fey, Marion Klaumuenzer, Alice Fabarius, PhD, Eva Riedl, MD, Alexander Marx, MD, Henning Roehl, MD, Nadine Mueller, MD, Georgia Metzgeroth, MD, Gero Huetter, MD, Wolf-Karsten Hofmann, Andreas Trumpp, PhD, Daniel Nowak, MD

Blood (2012) 120 (21): 1694.

https://doi.org/10.1182/blood.V120.21.1694.1694

Published: 2012

Journal Articles

Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Vincenzo Giambra, PhD, Oksana Nemirovsky, Sonya Lam, Christopher Jenkins, Carol Wai, Hind Medyouf, PhD, R. Keith Humphries, PhD, Connie J. Eaves, PhD, Andrew P Weng, MD, PhD

Blood (2010) 116 (21): 12.

https://doi.org/10.1182/blood.V116.21.12.12

Published: 2010

Journal Articles

High-Level IGF1R Expression Is Required for Leukemia Stem Cell Activity In T-ALL and Is Supported by Notch Signaling.

Hind Medyouf, PhD, Samuel Gusscott, Carol Wai, Oksana Nemirovsky, Vincenzo Giambra, PhD, Joan M Carboni, PhD, Marco Gottardis, PhD, Francoise Pflumio, PhD, Michael Pollak, MD, Martin Holzenberger, MD, PhD, Andrew P Weng, MD, PhD

Blood (2010) 116 (21): 3649.

https://doi.org/10.1182/blood.V116.21.3649.3649

Published: 2010

Journal Articles

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss

Hind Medyouf, Xiuhua Gao, Florence Armstrong, Samuel Gusscott, Qing Liu, Amanda Larson Gedman, Larry H. Matherly, Kirk R. Schultz, Francoise Pflumio, Mingjian James You, Andrew P. Weng

Blood (2010) 115 (6): 1175–1184.

https://doi.org/10.1182/blood-2009-04-214718

Published: 2010

Includes: Supplemental data

Journal Articles

Acute T-Cell Leukemias Remain Dependent On Notch Signaling Despite PTEN and INK4A/ARF Loss.

Hind Medyouf, Xiuhua Gao, Florence Armstrong, Samuel Gusscott, Qing Liu, BS, Amanda Larson Gedman, Larry Matherly, PhD, Kirk R. Schultz, MD, Francoise Pflumio, PhD, M. James You, MD, PhD, Andrew P. Weng, MD, PhD

Blood (2009) 114 (22): 8.

https://doi.org/10.1182/blood.V114.22.8.8

Published: 2009

Journal Articles

Polycomb Group Ring Finger 5 (PCGF5) Is a Notch Transcriptional Target and Regulates Cell Size and Cell Cycle in Hematopoietic Progenitors.

Chris L Cochrane, Hind Medyouf, PhD, Andrew P. Weng, MD, PhD

Blood (2008) 112 (11): 1325.

https://doi.org/10.1182/blood.V112.11.1325.1325

Published: 2008

Journal Articles

IGF Signaling Is Critical for Growth and Survival of T-Cell Acute Lymphoblastic Leukemia Cells and Is Potentiated by Notch Upregulation of IGF1R

Hind Medyouf, PhD, Samuel Gusscott, Carol Wai, Marcus Leung, Florence Armstrong, PhD, Francoise Pflumio, PhD, Michael Pollak, MD, Andrew P. Weng, MD, PhD

Blood (2008) 112 (11): 3811.

https://doi.org/10.1182/blood.V112.11.3811.3811

Published: 2008

Journal Articles

Calcineurin/NFAT Pathway Is a Novel Target of Therapeutic Interest in Lymphoid Malignancies.

Hind Medyouf, PhD, Helene Alcade, Caroline Berthier, Anne Janin, MD, Hugues de Thé, MD, Jacques Ghysdael

Blood (2006) 108 (11): 1827.

https://doi.org/10.1182/blood.V108.11.1827.1827

Published: 2006

NARROW

Efficacy and Safety of Bemcentinib in Patients with Myelodysplastic Syndromes or Acute Myeloid Leukemia Failing Hypomethylating Agents

Development and Exploitation of a Fully Human and Modular Organotypic Bone Marrow Niche Model to Study the Role of Stroma-Produced Factors in Human MDS

The microenvironment in human myeloid malignancies: emerging concepts and therapeutic implications

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Development of a DNA-Based Targeted Assay Suitable for Accurate Quantification of Chromosomal Deletions in Myelodysplastic Syndromes with Deletion (5q) and Other Clonal Diseases

Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

Next Generation Sequencing-Based Molecular Dissection Of Lineage-Specific Mutational Hierarchies In Oligoclonal Primary and Xenografted Myelodysplasia

Significant Engraftment of Immature Hematopoietic Cells From Patients with Low Risk Myelodysplastic Syndromes (MDS) in Immunodeficient Mice

Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

High-Level IGF1R Expression Is Required for Leukemia Stem Cell Activity In T-ALL and Is Supported by Notch Signaling.

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss

Acute T-Cell Leukemias Remain Dependent On Notch Signaling Despite PTEN and INK4A/ARF Loss.

Polycomb Group Ring Finger 5 (PCGF5) Is a Notch Transcriptional Target and Regulates Cell Size and Cell Cycle in Hematopoietic Progenitors.

IGF Signaling Is Critical for Growth and Survival of T-Cell Acute Lymphoblastic Leukemia Cells and Is Potentiated by Notch Upregulation of IGF1R

Calcineurin/NFAT Pathway Is a Novel Target of Therapeutic Interest in Lymphoid Malignancies.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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