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Impact of early transcranial Doppler screening and intensive therapy on cerebral vasculopathy outcome in a newborn sickle cell anemia cohort
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results
Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia
Issue Archive
January 27 2011
In this Issue
Table of Contents
Inside blood
Perspectives
Review Article
Clinical Trials and Observations
Impact of early transcranial Doppler screening and intensive therapy on cerebral vasculopathy outcome in a newborn sickle cell anemia cohort
CME
Françoise Bernaudin,Suzanne Verlhac,Cécile Arnaud,Annie Kamdem,Sylvie Chevret,Isabelle Hau,Lena Coïc,Emmanuella Leveillé,Elisabeth Lemarchand,Emmanuelle Lesprit,Isabelle Abadie,Nadia Medejel,Fouad Madhi,Sophie Lemerle,Sandra Biscardi,Josiane Bardakdjian,Frédéric Galactéros,Martine Torres,Mathieu Kuentz,Christelle Ferry,Gérard Socié,Philippe Reinert,Christophe Delacourt
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results
Clinical Trials & Observations
Hagop M. Kantarjian,Francis J. Giles,Kapil N. Bhalla,Javier Pinilla-Ibarz,Richard A. Larson,Norbert Gattermann,Oliver G. Ottmann,Andreas Hochhaus,Jerald P. Radich,Giuseppe Saglio,Timothy P. Hughes,Giovanni Martinelli,Dong-Wook Kim,Yaping Shou,Neil J. Gallagher,Rick Blakesley,Michele Baccarani,Jorge Cortes,Philipp D. le Coutre
Gene Therapy
CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells
Jennifer D. Bassett,Teng Chih Yang,Dannie Bernard,James B. Millar,Stephanie L. Swift,A. J. Robert McGray,Heather VanSeggelen,Jeanette E. Boudreau,Jonathan D. Finn,Robin Parsons,Carole Evelegh,Daniela Damjanovic,Natalie Grinshtein,Maziar Divangahi,Liang Zhang,Zhou Xing,Yonghong Wan,Jonathan L. Bramson
Hematopoiesis and Stem Cells
Immunobiology
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
Thierry Roger,Jérôme Lugrin,Didier Le Roy,Geneviève Goy,Matteo Mombelli,Thibaud Koessler,Xavier C. Ding,Anne-Laure Chanson,Marlies Knaup Reymond,Isabelle Miconnet,Jacques Schrenzel,Patrice François,Thierry Calandra
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
Shuling Zhang,Julie A. Readinger,Wendy DuBois,Mirkka Janka-Junttila,Richard Robinson,Margaret Pruitt,Val Bliskovsky,Julie Z. Wu,Kaori Sakakibara,Jyoti Patel,Carole A. Parent,Lino Tessarollo,Pamela L. Schwartzberg,Beverly A. Mock
Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters
e-blood
Bence György,Károly Módos,Éva Pállinger,Krisztina Pálóczi,Mária Pásztói,Petra Misják,Mária A. Deli,Áron Sipos,Anikó Szalai,István Voszka,Anna Polgár,Kálmán Tóth,Mária Csete,György Nagy,Steffen Gay,András Falus,Ágnes Kittel,Edit I. Buzás
Lymphoid Neoplasia
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78
Gaël Roué,Patricia Pérez-Galán,Ana Mozos,Mónica López-Guerra,Sílvia Xargay-Torrent,Laia Rosich,Ifigènia Saborit-Villarroya,Emmanuel Normant,Elias Campo,Dolors Colomer
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
Brief Report
Ioanna Papandreou,Nicholas C. Denko,Michael Olson,Heleen Van Melckebeke,Sofie Lust,Arvin Tam,David E. Solow-Cordero,Donna M. Bouley,Fritz Offner,Maho Niwa,Albert C. Koong
Phagocytes, Granulocytes, and Myelopoiesis
Myeloperoxidase attracts neutrophils by physical forces
Anna Klinke,Claudia Nussbaum,Lukas Kubala,Kai Friedrichs,Tanja K. Rudolph,Volker Rudolph,Hans-Joachim Paust,Christine Schröder,Daniel Benten,Denise Lau,Katalin Szocs,Paul G. Furtmüller,Peter Heeringa,Karsten Sydow,Hans-Jürgen Duchstein,Heimo Ehmke,Udo Schumacher,Thomas Meinertz,Markus Sperandio,Stephan Baldus
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia
Brief Report
Julie Makani,Stephan Menzel,Siana Nkya,Sharon E. Cox,Emma Drasar,Deogratius Soka,Albert N. Komba,Josephine Mgaya,Helen Rooks,Nisha Vasavda,Gregory Fegan,Charles R. Newton,Martin Farrall,Swee Lay Thein
Thrombosis and Hemostasis
Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
Zurina Romay-Penabad,Renan Aguilar-Valenzuela,Rolf T. Urbanus,Ronald H. W. M. Derksen,Maarten T. T. Pennings,Elizabeth Papalardo,Tuya Shilagard,Gracie Vargas,Yong Hwang,Philip G. de Groot,Silvia S. Pierangeli
Transplantation
Vascular Biology
Other Departments
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Cover Image
Cover Image
Tracks of neutrophils (green) and macrophages (red) in the period 6 to 9 hours after wounding of a zebrafish embryo tail. Macrophages dwell at the wound margin (right), whereas neutrophils resume a peripatetic behavior throughout the tail. The image is a maximum-intensity projection of transgenically marked leukocytes imaged in vivo in a compound Tg(mpx:EGFP/mpeg1:Gal4-VP16/UAS:Kaede) zebrafish embryo, extracted from the primary source file for supplemental Video 3 of Ellett et al on page e49.
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