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Volume 104, Issue 4

August 15 2004

In this Issue

INSIDE BLOOD
PERSPECTIVES
REVIEW ARTICLES
RETRACTIONS
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

NEOPLASIA

Population dynamics and clonal dominance in tumors?

Eva A. Turley,James B. McCarthy

View Articletitled, Population dynamics and clonal dominance in tumors?

GENE THERAPY

Liver gene transfer keeps immune system in check

Thierry VandenDriessche

View Articletitled, Liver gene transfer keeps immune system in check

CHEMOKINES

CCR2: holding B cells back

Dan Jones, M. D.

View Articletitled, CCR2: holding B cells back

CLINICAL OBSERVATIONS, INTERVENTIONS, & THERAPEUTIC TRIALS

ITP: the bad actors

Alan Lichtin

View Articletitled, ITP: the bad actors

HEMOSTASIS, THROMBOSIS, & VASCULAR BIOLOGY

Platelets feel your pain

Robert Flaumenhaft

View Articletitled, Platelets feel your pain

IMMUNOBIOLOGY

Signal strength and persistence control DC fate

Christophe Caux

View Articletitled, Signal strength and persistence control DC fate

IMMUNOBIOLOGY

Imatinib mesylate: a novel immune suppressive agent?

Richard T. Maziarz

View Articletitled, Imatinib mesylate: a novel immune suppressive agent?

NEOPLASIA

FLT3 target practice

Richard M. Stone

View Articletitled, FLT3 target practice

TRANSPLANTATION

MR-based cellular imaging: ready for prime time?

Terence P. F. Gade,Jason A. Koutcher

View Articletitled, MR-based cellular imaging: ready for prime time?

PERSPECTIVES

Dimerization: a versatile switch for oncogenesis

Chi Wai So,Michael L. Cleary

View Articletitled, Dimerization: a versatile switch for oncogenesis

REVIEW ARTICLES

Genomic approaches to hematologic malignancies

Benjamin L. Ebert,Todd R. Golub

View Articletitled, Genomic approaches to hematologic malignancies

RETRACTIONS

Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells

Irene M. Pedersen,Juan M. Zapata,Temesgen Samuel,Fiona L. Scott,Guy S. Salvesen,Tadashi Honda,Gordon W. Gribble,Nanjoo Suh,Michael B. Sporn,Thomas J. Kipps,John C. Reed

View Articletitled, Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells

CHEMOKINES

Expression of the chemokine receptor CCR2 on immature B cells negatively regulates their cytoskeletal rearrangement and migration

Liat Flaishon,Shirly Becker-Herman,Gili Hart,Yoram Levo,William A. Kuziel,Idit Shachar

View Articletitled, Expression of the chemokine receptor CCR2 on immature B cells negatively regulates their cytoskeletal rearrangement and migration

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Immune activation set point during early HIV infection predicts subsequent CD4⁺ T-cell changes independent of viral load
Clinical Trials & Observations

Steven G. Deeks,Christina M. R. Kitchen,Lea Liu,Hua Guo,Ron Gascon,Amy B. Narváez,Peter Hunt,Jeffrey N. Martin,James O. Kahn,Jay Levy,Michael S. McGrath,Frederick M. Hecht

View Articletitled, Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration
Clinical Trials & Observations

Geoff Hale,Peppy Rebello,Lee R. Brettman,Chris Fegan,Ben Kennedy,Eva Kimby,Mike Leach,Jeanette Lundin,Håkan Mellstedt,Paul Moreton,Andy C. Rawstron,Herman Waldmann,Anders Osterborg,Peter Hillmen

View Articletitled, Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration

Long-term outcomes in adults with chronic ITP after splenectomy failure
Clinical Trials & Observations

Robert McMillan,Carol Durette

View Articletitled, Long-term outcomes in adults with chronic ITP after splenectomy failure

Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities
Clinical Trials & Observations

Mohamed L. Sorror,Michael B. Maris,Barry Storer,Brenda M. Sandmaier,Razvan Diaconescu,Christopher Flowers,David G. Maloney,Rainer Storb

View Articletitled, Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities

GENE THERAPY

Induction of antigen-specific CD4⁺ T-cell anergy and deletion by in vivo viral gene transfer

Eric Dobrzynski,Federico Mingozzi,Yi-Lin Liu,Elisabeth Bendo,Ou Cao,Lixin Wang,Roland W. Herzog

View Articletitled, Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer

HEMATOPOIESIS

Inhibition of angiotensin I–converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells

Sabine Charrier,Annie Michaud,Sabrina Badaoui,Sébastien Giroux,Eric Ezan,Françoise Sainteny,Pierre Corvol,William Vainchenker

View Articletitled, Inhibition of angiotensin I–converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells

Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation

Yutaka Sasaki,Christina T. Jensen,Stefan Karlsson,Sten Eirik W. Jacobsen

View Articletitled, Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation

The integrin αMβ2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization

Andrés Hidalgo,Anna J. Peired,Linnea A. Weiss,Yoshio Katayama,Paul S. Frenette

View Articletitled, The integrin αMβ2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID–ß₂m^–/– repopulating cells.

Masayoshi Kobune,Yoshinori Ito,Yutaka Kawano,Katsunori Sasaki,Hiroaki Uchida,Kiminori Nakamura,Hironari Dehari,Hiroki Chiba,Rishu Takimoto,Takuya Matsunaga,Takeshi Terui,Junji Kato,Yoshiro Niitsu,Hirofumi Hamada

View Articletitled, Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID–ß2m–/– repopulating cells.

PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors

Christina I. Baumann,Alexis S. Bailey,Weiming Li,Michael J. Ferkowicz,Mervin C. Yoder,William H. Fleming

View Articletitled, PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors

Megakaryocytes express functional Aurora-B kinase in endomitosis

Amy E. Geddis,Kenneth Kaushansky

View Articletitled, Megakaryocytes express functional Aurora-B kinase in endomitosis

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Syndecan-1 up-regulated by ephrinB2/EphB4 plays dual roles in inflammatory angiogenesis

Kuo Yuan,Tse-Ming Hong,Jeremy J. W. Chen,Wan Hua Tsai,Ming T. Lin

View Articletitled, Syndecan-1 up-regulated by ephrinB2/EphB4 plays dual roles in inflammatory angiogenesis

Fibrin-incorporated vitronectin is involved in platelet adhesion and thrombus formation through homotypic interactions with platelet-associated vitronectin

Ya-Ping Wu,Haiko J. Bloemendal,Emile E. Voest,Ton Logtenberg,Philip G. de Groot,Martijn F. B. G. Gebbink,Hetty C. de Boer

View Articletitled, Fibrin-incorporated vitronectin is involved in platelet adhesion and thrombus formation through homotypic interactions with platelet-associated vitronectin

A TREM family member, TLT-1, is found exclusively in the α-granules of megakaryocytes and platelets

A. Valance Washington,Rebecca L. Schubert,Laura Quigley,Theresa Disipio,Robert Feltz,Edward H. Cho,Daniel W. McVicar

View Articletitled, A TREM family member, TLT-1, is found exclusively in the α-granules of megakaryocytes and platelets

Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia

Rainer Kunstfeld,Satoshi Hirakawa,Young-Kwon Hong,Vivien Schacht,Bernhard Lange-Asschenfeldt,Paula Velasco,Charles Lin,Edda Fiebiger,Xunbin Wei,Yan Wu,Daniel Hicklin,Peter Bohlen,Michael Detmar

View Articletitled, Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia

Tachykinins regulate the function of platelets

Gwenda J. Graham,Joanne M. Stevens,Nigel M. Page,Andrew D. Grant,Susan D. Brain,Philip J. Lowry,Jonathan M. Gibbins

View Articletitled, Tachykinins regulate the function of platelets

IMMUNOBIOLOGY

Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells

Thomas Luft,Eugene Maraskovsky,Max Schnurr,Katja Knebel,Michael Kirsch,Martin Görner,Radek Skoda,Anthony D. Ho,Peter Nawroth,Angelika Bierhaus

View Articletitled, Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8⁺ cytotoxic T-cell response in natural infection

Thomas J. Manley,Lisa Luy,Thomas Jones,Michael Boeckh,Helen Mutimer,Stanley R. Riddell

View Articletitled, Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection

LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56⁺CD8⁺ natural killer cells

Omar D. Perez,Dennis Mitchell,Gina C. Jager,Garry P. Nolan

View Articletitled, LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells

Supplemental data

Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo

Allan B. Dietz,Lina Souan,Gaylord J. Knutson,Peggy A. Bulur,Mark R. Litzow,Stanimir Vuk-Pavlović

View Articletitled, Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo

Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity

Sandip Bhattacharyya,Pradip Sen,Mark Wallet,Brian Long,Albert S. Baldwin, Jr,Roland Tisch

View Articletitled, Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity

Supplemental data

Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function

Yu-Waye Chu,Sarfraz A. Memon,Susan O. Sharrow,Frances T. Hakim,Michael Eckhaus,Philip J. Lucas,Ronald E. Gress

View Articletitled, Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function

NEOPLASIA

Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels

Katja Specht,Eugenia Haralambieva,Karin Bink,Marcus Kremer,Sonja Mandl-Weber,Ina Koch,Raju Tomer,Heinz Hofler,Ed Schuuring,Philip M. Kluin,Falko Fend,Leticia Quintanilla-Martinez

View Articletitled, Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels

NUP98-Topoisomerase I acute myeloid leukemia-associated fusion gene has potent leukemogenic activities independent of an engineered catalytic site mutation

Rhonna M. Gurevich,Peter D. Aplan,R. Keith Humphries

View Articletitled, NUP98-Topoisomerase I acute myeloid leukemia-associated fusion gene has potent leukemogenic activities independent of an engineered catalytic site mutation

Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody

Yiwen Li,Hongli Li,Mei-Nai Wang,Dan Lu,Rajiv Bassi,Yan Wu,Haifan Zhang,Paul Balderes,Dale L. Ludwig,Bronislaw Pytowski,Paul Kussie,Obdulio Piloto,Donald Small,Peter Bohlen,Larry Witte,Zhenping Zhu,Daniel J. Hicklin

View Articletitled, Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody

Supplemental data

In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects

Mark Levis,Rosalyn Pham,B. Douglas Smith,Donald Small

View Articletitled, In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma
Clinical Trials & Observations

Christopher A. Maxwell,Erik Rasmussen,Fenghuang Zhan,Jonathan J. Keats,Sophia Adamia,Erin Strachan,Mary Crainie,Ronald Walker,Andrew R. Belch,Linda M. Pilarski,Bart Barlogie,John Shaughnessy, Jr,Tony Reiman

View Articletitled, RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma

Bone marrow angiogenic ability and expression of angiogenic cytokines in myeloma: evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression

Shaji Kumar,Thomas E. Witzig,Michael Timm,Jessica Haug,Linda Wellik,Teresa K. Kimlinger,Philip R. Greipp,S. Vincent Rajkumar

View Articletitled, Bone marrow angiogenic ability and expression of angiogenic cytokines in myeloma: evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression

Rituximab antiproliferative effect in B-lymphoma cells is associated with acid-sphingomyelinase activation in raft microdomains

Christine Bezombes,Solène Grazide,Céline Garret,Claire Fabre,Anne Quillet-Mary,Sabina Müller,Jean-Pierre Jaffrézou,Guy Laurent

View Articletitled, Rituximab antiproliferative effect in B-lymphoma cells is associated with acid-sphingomyelinase activation in raft microdomains

PHAGOCYTES

Regulation of monocyte migration by amphoterin (HMGB1)

Ari Rouhiainen,Juha Kuja-Panula,Erika Wilkman,Jukka Pakkanen,Jan Stenfors,Raimo K. Tuominen,Mauri Lepäntalo,Olli Carpén,Jaakko Parkkinen,Heikki Rauvala

View Articletitled, Regulation of monocyte migration by amphoterin (HMGB1)

CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells

Adriana R. Mantegazza,María Marcela Barrio,Sandrine Moutel,Laura Bover,Markus Weck,Peter Brossart,Jean-Luc Teillaud,José Mordoh

View Articletitled, CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells

Supplemental data

Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses

Anita Mangla,Anupriya Khare,Varanasi Vineeth,Nagesh Narayan Panday,Asok Mukhopadhyay,Balachandran Ravindran,Vineeta Bal,Anna George,Satyajit Rath

View Articletitled, Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses

RED CELLS

The etiology of severe anemia in a village and a periurban area in Mali
Clinical Trials & Observations Brief Report

Alassane Dicko,Amy D. Klion,Mahamadou A. Théra,Issaka Sagara,Daniel Yalcouyé,Mohamed B. Niambele,Moussa Sogoba,Guimogo Dolo,Adama Dao,Dapa A. Diallo,Ogobara K. Doumbo,Louis H. Miller

View Articletitled, The etiology of severe anemia in a village and a periurban area in Mali

TRANSPLANTATION

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years
Clinical Trials & Observations

Pietro Sodani,David Gaziev,Paola Polchi,Buket Erer,Claudio Giardini,Emanuele Angelucci,Donatella Baronciani,Marco Andreani,Marisa Manna,Sonia Nesci,Barbarella Lucarelli,Reginald A. Clift,Guido Lucarelli

View Articletitled, New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years

Continuous in vivo infusion of interferon-gamma (IFN-γ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc^-/- mice

Xiaxin Li,Yanzhu Yang,Jin Yuan,Ping Hong,Brian Freie,Attilio Orazi,Laura S. Haneline,D. Wade Clapp

View Articletitled, Continuous in vivo infusion of interferon-gamma (IFN-γ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8⁺ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets

Matthias Stelljes,Robert Strothotte,Hans-Gerd Pauels,Christopher Poremba,Michaela Milse,Christiane Specht,Jörn Albring,Guido Bisping,Christian Scheffold,Thomas Kammertoens,Elisabeth Oelmann,Gerda Silling,Wolfgang E. Berdel,Joachim Kienast

View Articletitled, Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets

Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI

Ali S. Arbab,Gene T. Yocum,Heather Kalish,Elaine K. Jordan,Stasia A. Anderson,Aarif Y. Khakoo,Elizabeth J. Read,Joseph A. Frank

View Articletitled, Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI

Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Brief Report

Vincent T. Ho,David Zahrieh,Ephraim Hochberg,Eileen Micale,Jesse Levin,Carol Reynolds,Steve Steckel,Corey Cutler,David C. Fisher,Stephanie J. Lee,Edwin P. Alyea,Jerome Ritz,Robert J. Soiffer,Joseph H. Antin

View Articletitled, Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

CORRESPONDENCE

Role of splenectomy in inherited thrombocytopenias

Carlo L. Balduini

View Articletitled, Role of splenectomy in inherited thrombocytopenias

Association of HCV-related mixed cryoglobulinemia with specific mutational pattern of the HCV E2 protein and CD81 expression on peripheral B lymphocytes

Wolf Peter Hofmann,Eva Herrmann,Bernd Kronenberger,Christian Merkwirth,Christoph Welsch,Thomas Lengauer,Stefan Zeuzem,Christoph Sarrazin

View Articletitled, Association of HCV-related mixed cryoglobulinemia with specific mutational pattern of the HCV E2 protein and CD81 expression on peripheral B lymphocytes

Induction of imatinib metabolism by hypericum perforatum

Patrick F. Smith,Julie M. Bullock,Brent M. Booker,Curtis E. Haas,Charles S. Berenson,William J. Jusko

View Articletitled, Induction of imatinib metabolism by hypericum perforatum

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Issue Archive

Table of Contents

INSIDE BLOOD

PERSPECTIVES

REVIEW ARTICLES

RETRACTIONS

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load Clinical Trials & Observations

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration Clinical Trials & Observations

Long-term outcomes in adults with chronic ITP after splenectomy failure Clinical Trials & Observations

Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

NEOPLASIA

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma Clinical Trials & Observations

PHAGOCYTES

RED CELLS

The etiology of severe anemia in a village and a periurban area in Mali Clinical Trials & Observations Brief Report

TRANSPLANTATION

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years Clinical Trials & Observations

Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation Brief Report

CORRESPONDENCE

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American Society of Hematology

This Feature Is Available To Subscribers Only

Immune activation set point during early HIV infection predicts subsequent CD4⁺ T-cell changes independent of viral load
Clinical Trials & Observations

Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration
Clinical Trials & Observations

Long-term outcomes in adults with chronic ITP after splenectomy failure
Clinical Trials & Observations

Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities
Clinical Trials & Observations

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma
Clinical Trials & Observations

The etiology of severe anemia in a village and a periurban area in Mali
Clinical Trials & Observations Brief Report

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years
Clinical Trials & Observations

Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Brief Report