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Journal Articles

Chemotherapy for Acute Myeloid Leukemia Can Compensate Other Adverse Prognostic Factors in Elderly: A Retrospective Longitudinal Cohort Study in a Local Community, Japan

Osamu Imataki, MD, Hiroaki Ohnishi, MD, Yasunori Kawachi, M.D., Makoto Ide, M.D., Ph.D., Makiko Uemura, M.D., Kimihiro Kawakami, M.D., Ph.D., Akihito Matsuoka, M.D., Ph.D., Masato Waki, M.D., Ph.D., Hidetaka Takimoto, MD, Yasuo Hoshijima, M.D., Ph.D., Tetsuya Fukumoto, M.D., Ph.D., Kensuke Matsumoto, M.D., Ph.D., Fusako Waki, MD, Teruhisa Taoka, M.D., Ph.D., Takuya Matsunaga, MD, PhD

Blood (2012) 120 (21): 3582.

https://doi.org/10.1182/blood.V120.21.3582.3582

Published: 2012

Journal Articles

R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm

Blood (2011) 117 (25): 6866–6875.

https://doi.org/10.1182/blood-2010-01-262535

Published: 2011

Includes: Supplemental data

Journal Articles

NS-018, a Potent Novel JAK2 Inhibitor, Effectively Treats Murine MPN Induced by the Janus Kinase 2 (JAK2) V617F Mutant

Kotaro Shide, Yohei Nakaya, Takuro Kameda, Haruko Shimoda, Tomonori Hidaka, Yoko Kubuki, Keiko Katayose, Takuya Matsunaga, Junko Homan, Takashi Kotera, Hiroshi Shibayama, Haruna Naito, Kazuya Shimoda

Blood (2010) 116 (21): 4106.

https://doi.org/10.1182/blood.V116.21.4106.4106

Published: 2010

Journal Articles

Potentiated Activation of VLA-4 and VLA-5 Accelerates Proplatelet-Like Formation In Megakaryocytes.

Takuya Matsunaga, MD, PhD, Fumio Fukai, PhD, Takuro Kameda, MD, Kotaro Shide, MD, PhD, Haruko Shimoda, MD, PhD, Eri Torii, Yasuhiro Taniguchi, Tomonori Hidaka, Keiko Katayose, Yoko Kubuki, Kazuya Shimoda, MD, PhD

Blood (2010) 116 (21): 2585.

https://doi.org/10.1182/blood.V116.21.2585.2585

Published: 2010

Journal Articles

Efficacy of R723, a Potent and Selective JAK2 Inhibitor, in JAK2 V617F-Induced Murine MPD Model.

Kotaro Shide, Takuro Kameda, Vadim Markovtsov, Takuya Matsunaga, Haruko Shimoda, Tomonori Hidaka, Keiko Katayose, Yoko Kubuki, Somasekhar Bhamidipati, Gary Park, Allan Torneros, Matt Duan, Yasumichi Hitoshi, Kazuya Shimoda

Blood (2009) 114 (22): 3897.

https://doi.org/10.1182/blood.V114.22.3897.3897

Published: 2009

Journal Articles

Absence of Somatically Acquired JAK1 Mutations in Adult T-Cell Leukemia/Lymphoma.

Takuro Kameda, MD, Kotaro Shide, MD, PhD, Haruko Shimoda, MD, PhD, Tomonori Hidaka, MD, PhD, Keiko Katayose, MD, Yasuhiro Taniguchi, MD, Kohich Maeda, MD, Yoko Kubuki, MD, PhD, Takuya Matsunaga, MD, PhD, Kazuya Shimoda, MD, PhD

Blood (2009) 114 (22): 1921.

https://doi.org/10.1182/blood.V114.22.1921.1921

Published: 2009

Journal Articles

Wnt3 / RhoA / ROCK Signaling Pathway Is Involved in VLA6-Dependent Adhesion-Mediated Drug Resistance of Multiple Myeloma.

Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Junji Kato, MD, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2007) 110 (11): 2518.

https://doi.org/10.1182/blood.V110.11.2518.2518

Published: 2007

Journal Articles

Treatment of Idiopathic Myelofibrosis Employing siRNA for Heat Shock Protein 47 (siRNA/HSP47) Encapsulated in Liposomes.

Junichi Watanabe, MD, Takuya Matsunaga, MD, PhD, Kazuyuki Murase, MD, PhD, Yasushi Sato, MD, PhD, Taiko Nagaya, Hirotoshi Ishiwatari, MD, Sho Takahashi, MD, PhD, Koichi Takada, MD, PhD, Masayoshi Kobune, MD, PhD, Kazuya Shimoda, MD, PhD, Mine Harada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2007) 110 (11): 4646.

https://doi.org/10.1182/blood.V110.11.4646.4646

Published: 2007

Journal Articles

Combination Therapy of Anti-Cancer Drug with FNIII14 Peptide of Fibronectin Effectively Overcome Cell Adhesion Mediated-Drug Resistance of Acute Myelogenous Leukemia.

Takuya Matsunaga, MD, PhD, Fumio Fukai, PhD, Maki Tanaka, MD, Masayoshi Kobune, MD, Hiroki Chiba, MD, Yoshiro Niitsu, MD

Blood (2006) 108 (11): 527.

https://doi.org/10.1182/blood.V108.11.527.527

Published: 2006

Journal Articles

Late Onset Neutropenia and Decreased Immunoglobulin Concentration after Rituximab Combined Autotransplantation for B Cell Lymphoma.

Yasuo Hirayama, Kyuhei Kohda, Yasuji Hirata, Hiroyuki Kuroda, Takuya Matsunaga, Yuichi Konuma, Makoto Yoshida, Toshiro Sakai, Yoshiro Niitsu

Blood (2005) 106 (11): 5347.

https://doi.org/10.1182/blood.V106.11.5347.5347

Published: 2005

Journal Articles

Ex Vivo Large Scale Generation of Human Platelets from Cord Blood CD34+ Cells.

Takuya Matsunaga, MD, PhD, Ikuta Tanaka, MD, PhD, Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Maki Tanaka, MD, PhD, Takehide Akiyama, MD, Kageaki Kuribayashi, MD, PhD, Takafumi Ninomiya, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2005) 106 (11): 1892.

https://doi.org/10.1182/blood.V106.11.1892.1892

Published: 2005

Journal Articles

Wnt3 Augments Adhesion Mediated Drug Resistance of Myeloma Cells Via Wnt/RhoA Pathway.

Hiroki Chiba, MD, Masayoshi Kobune, MD, PhD, Kazunori Kato, PhD, Kiminori Nakamura, PhD, Yutaka Kawano, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Junji Kato, MD, PhD, Yoshiro Niitsu, MD, PhD, Hirofumi Hamada, MD, PhD

Blood (2005) 106 (11): 5075.

https://doi.org/10.1182/blood.V106.11.5075.5075

Published: 2005

Journal Articles

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion

Yasushi Sato, Hironobu Araki, Junji Kato, Kiminori Nakamura, Yutaka Kawano, Masayoshi Kobune, Tsutomu Sato, Koji Miyanishi, Tetsuji Takayama, Minoru Takahashi, Rishu Takimoto, Satoshi Iyama, Takuya Matsunaga, Seiji Ohtani, Akihiro Matsuura, Hirofumi Hamada, Yoshiro Niitsu

Blood (2005) 106 (2): 756–763.

https://doi.org/10.1182/blood-2005-02-0572

Published: 2005

Journal Articles

Combination Therapy of Humanized Chimeric-Anti-Human VLA4 Monoclonal Antibodies and Anti-Cancer Drugs for AML.

Takuya Matsunaga, MD, Kazunori Kato, PhD, Maki Tanaka, MD, Yukari Masuta, PhD, Kageaki Kuribayashi, MD, Naofumi Takemoto, MD, Ikuta Tanaka, MD, Akihito Fujimi, MD, Takehide Akiyama, MD, Hirofumi Hamada, MD, Yoshiro Niitsu, MD

Blood (2004) 104 (11): 4518.

https://doi.org/10.1182/blood.V104.11.4518.4518

Published: 2004

Journal Articles

Indian Hedgehog Stimulates Proliferation of Short-Term NOD/SCID-ß2m null Repopulating Cells on Coculture with Human Stromal Cells.

Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Junji Kato, MD, PhD, Yoshinori Ito, MD, Hiroki Chiba, MD, Kageaki Kuribayashi, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2004) 104 (11): 1300.

https://doi.org/10.1182/blood.V104.11.1300.1300

Published: 2004

Journal Articles

Ex Vivo Production of Transfusable Red Blood Cells at Large Scale from Cord Blood CD34+ Cells Using a Coculture System with Human Telomerase Catalytic Subunit (hTERT)-Transfected Human Stromal Cells at Early Phase and with Acitivated Macrophage from Cord Blood CD34+ Cells at Late Phase.

Akihito Fujimi, MD, Takuya Matsunaga, MD, Masayoshi Kobune, MD, Yutaka Kawano, MD, Ikuta Tanaka, MD, Naofumi Takemoto, MD, Takehide Akiyama, MD, Hirofumi Hamada, MD, Yoshiro Niitsu, MD

Blood (2004) 104 (11): 2701.

https://doi.org/10.1182/blood.V104.11.2701.2701

Published: 2004

Journal Articles

Impaired Expression of the DNA Repair Factor DDB2 in Human Myeloid Leukemias.

Rishu Takimoto, MD/PhD, Junji Kato, MD/PhD, Koichi Takada, MD/PhD, Takuya Matsunaga, MD/PhD, Yoshiro Niitsu, MD/PhD

Blood (2004) 104 (11): 2046.

https://doi.org/10.1182/blood.V104.11.2046.2046

Published: 2004

Journal Articles

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID– ß 2 m –/– repopulating cells.

Masayoshi Kobune, Yoshinori Ito, Yutaka Kawano, Katsunori Sasaki, Hiroaki Uchida, Kiminori Nakamura, Hironari Dehari, Hiroki Chiba, Rishu Takimoto, Takuya Matsunaga, Takeshi Terui, Junji Kato, Yoshiro Niitsu, Hirofumi Hamada

Blood (2004) 104 (4): 1002–1009.

https://doi.org/10.1182/blood-2003-09-3347

Published: 2004

Journal Articles

Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT) –transfected human stromal cells

Yutaka Kawano, Masayoshi Kobune, Miki Yamaguchi, Kiminori Nakamura, Yoshinori Ito, Katsunori Sasaki, Sho Takahashi, Takafumi Nakamura, Hiroki Chiba, Tsutomu Sato, Takuya Matsunaga, Hiroshi Azuma, Kenji Ikebuchi, Hisami Ikeda, Junji Kato, Yoshiro Niitsu, Hirofumi Hamada

Blood (2003) 101 (2): 532–540.

https://doi.org/10.1182/blood-2002-04-1268

Published: 2003

Journal Articles

Prevention of lethal acute graft-versus-host disease in mice by oral administration of T helper 1 inhibitor, TAK-603

Yue Lu, Sumio Sakamaki, Hiroyuki Kuroda, Toshiro Kusakabe, Yuichi Konuma, Takehide Akiyama, Akihito Fujimi, Naofumi Takemoto, Kyokusen Nishiie, Takuya Matsunaga, Yasuo Hirayama, Junji Kato, Shinichiro Kon, Katsuhisa Kogawa, Yoshiro Niitsu

Blood (2001) 97 (4): 1123–1130.

https://doi.org/10.1182/blood.V97.4.1123

Published: 2001

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Chemotherapy for Acute Myeloid Leukemia Can Compensate Other Adverse Prognostic Factors in Elderly: A Retrospective Longitudinal Cohort Study in a Local Community, Japan

R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm

NS-018, a Potent Novel JAK2 Inhibitor, Effectively Treats Murine MPN Induced by the Janus Kinase 2 (JAK2) V617F Mutant

Potentiated Activation of VLA-4 and VLA-5 Accelerates Proplatelet-Like Formation In Megakaryocytes.

Efficacy of R723, a Potent and Selective JAK2 Inhibitor, in JAK2 V617F-Induced Murine MPD Model.

Absence of Somatically Acquired JAK1 Mutations in Adult T-Cell Leukemia/Lymphoma.

Wnt3 / RhoA / ROCK Signaling Pathway Is Involved in VLA6-Dependent Adhesion-Mediated Drug Resistance of Multiple Myeloma.

Treatment of Idiopathic Myelofibrosis Employing siRNA for Heat Shock Protein 47 (siRNA/HSP47) Encapsulated in Liposomes.

Combination Therapy of Anti-Cancer Drug with FNIII14 Peptide of Fibronectin Effectively Overcome Cell Adhesion Mediated-Drug Resistance of Acute Myelogenous Leukemia.

Late Onset Neutropenia and Decreased Immunoglobulin Concentration after Rituximab Combined Autotransplantation for B Cell Lymphoma.

Ex Vivo Large Scale Generation of Human Platelets from Cord Blood CD34+ Cells.

Wnt3 Augments Adhesion Mediated Drug Resistance of Myeloma Cells Via Wnt/RhoA Pathway.

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion

Combination Therapy of Humanized Chimeric-Anti-Human VLA4 Monoclonal Antibodies and Anti-Cancer Drugs for AML.

Indian Hedgehog Stimulates Proliferation of Short-Term NOD/SCID-ß2m null Repopulating Cells on Coculture with Human Stromal Cells.

Ex Vivo Production of Transfusable Red Blood Cells at Large Scale from Cord Blood CD34+ Cells Using a Coculture System with Human Telomerase Catalytic Subunit (hTERT)-Transfected Human Stromal Cells at Early Phase and with Acitivated Macrophage from Cord Blood CD34+ Cells at Late Phase.

Impaired Expression of the DNA Repair Factor DDB2 in Human Myeloid Leukemias.

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID– ß 2 m –/– repopulating cells.

Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT) –transfected human stromal cells

Prevention of lethal acute graft-versus-host disease in mice by oral administration of T helper 1 inhibitor, TAK-603

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