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Journal Articles

Preclinical Studies for Sickle Cell Disease Gene Therapy Using Bone Marrow CD34+ Cells Modified with a βAS3-Globin Lentiviral Vector

Fabrizia Urbinati, Ph.D, Zulema Romero Garcia, Ph.D, Sabine Geiger, Rafael Ruiz de Assin, Ph.D, Gabriela Kuftinec, Roger P. Hollis, PhD, Satiro N. De Oliveira, MD, Jennifer Wherley, Aaron Cooper, Tim M. Townes, PhD, Gay M. Crooks, MBBS, Elizabeth J Read, MD, Mark C. Walters, MD, Herbert J. Meiselman, ScD, Thomas D. Coates, MD, Victor J. Marder, M.D., Donald B. Kohn, MD

Blood (2011) 118 (21): 3119.

https://doi.org/10.1182/blood.V118.21.3119.3119

Published: 2011

Journal Articles

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Stephan Mielke, Raquel Nunes, Katayoun Rezvani, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, Yong Fan, Emma Gostick, David A. Price, Christian Scotto, Elizabeth J. Read, A. John Barrett

Blood (2008) 111 (8): 4392–4402.

https://doi.org/10.1182/blood-2007-08-104471

Published: 2008

Includes: Supplemental data

Journal Articles

Successful Translation of a GMP-Based, Clinical Scale Selective Allodepletion Approach for Matched Donor-Recipient Pairs from Bench-to-Bedside.

Stephan Mielke, MD, Raquel Nunes, MD, Katayoun Rezvani, MD, PhD, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, MD, Yong Fan, MD, Christian Scotto, PhD, Elizabeth J. Read, MD, A. John Barrett, MD

Blood (2007) 110 (11): 3279.

https://doi.org/10.1182/blood.V110.11.3279.3279

Published: 2007

Journal Articles

Reconstitution of FOXP3 + regulatory T cells (T regs ) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease

Stephan Mielke, Katayoun Rezvani, Bipin N. Savani, Raquel Nunes, Agnes S. M. Yong, John Schindler, Roger Kurlander, Victor Ghetie, Elizabeth J. Read, Scott R. Solomon, Ellen S. Vitetta, A. John Barrett

Blood (2007) 110 (5): 1689–1697.

https://doi.org/10.1182/blood-2007-03-079160

Published: 2007

Journal Articles

Prolonging the Incubation of Monocytes with GM-CSF and IL-4 for More Than 3 Days during the Generation of Dendritic Cells (DCS) In Vitro Markedly Diminishes IL-12 and Increases IL-10 Production When DCS Are Subsequently Matured.

Abdul Tawab, PhD, Yong Fan, M.D., Thao Mai, M.T., Elizabeth J. Read, M.D., Roger J. Kurlander, MD

Blood (2006) 108 (11): 3653.

https://doi.org/10.1182/blood.V108.11.3653.3653

Published: 2006

Journal Articles

Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts Preserves a CD25− CD4+foxp3+ Fraction of T Cells and Thereby Provides a Source for Efficient Reconstitution of Regulatory T Cells and Additional GVHD Control.

Stephan Mielke, MD, Katayoun Rezvani, MD, PhD, Scott R. Solomon, MD, Bipin N. Savani, MD, Raquel Nunes, MD, Agnes Yong, MD, PhD, John Schindler, PhD, Elizabeth J. Read, MD, Ellen S. Vitetta, PhD, A. John Barrett, MD

Blood (2006) 108 (11): 308.

https://doi.org/10.1182/blood.V108.11.308.308

Published: 2006

Journal Articles

Total Lymphocyte and Natural Killer (NK) Cell Count Day 30 Post-Transplant Strongly Predict Transplant Outcome after T Cell Depleted Allogeneic Stem Cell Transplantation.

Bipin N. Savani, MD, Stephan Mielke, MD, Katayoun Rezvani, MD, PhD, Agnes Yong, MD, PhD, Nancy Hensel, Elizabeth J. Read, MD, Richard Childs, A. John Barrett, MD

Blood (2006) 108 (11): 2993.

https://doi.org/10.1182/blood.V108.11.2993.2993

Published: 2006

Journal Articles

High Efficiency Clinical Scale Selective Depletion of Alloreacting T Cells Using Expanded T Lymphocytes as Antigen-Presenting Cells and a TH9402-Based Photodepletion Technique in HLA-Mismatched and Matched Donor-Recipient Pairs.

Stephan Mielke, MD, Raquel Nunes, MD, Katayoun Rezvani, MD, PhD, Vicki S. Fellowes, Yong Fan, MD, Scott R. Solomon, MD, Christian Scotto, PhD, Elizabeth J. Read, MD, A. John Barrett, MD

Blood (2006) 108 (11): 721.

https://doi.org/10.1182/blood.V108.11.721.721

Published: 2006

Journal Articles

Factors associated with early molecular remission after T cell-depleted allogeneic stem cell transplantation for chronic myelogenous leukemia

Bipin N. Savani, Katayoun Rezvani, Stephan Mielke, Aldemar Montero, Roger Kurlander, Charles S. Carter, Susan Leitman, Elizabeth J. Read, Richard Childs, A. John Barrett

Blood (2006) 107 (4): 1688–1695.

https://doi.org/10.1182/blood-2005-05-1897

Published: 2006

Journal Articles

Reconstitution of Regulatory T Cells after Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts and Association with Acute Graft-Versus-Host-Disease.

Stephan Mielke, MD, Katayoun Rezvani, MD, PhD, Scott R. Solomon, MD, Yasemin Kilical, Bipin N. Savani, MD, Laura Wish, Charles S. Carter, John Schindler, PhD, Nancy Hensel, Roger Kurlander, MD, Elizabeth J. Read, MD, Ellen S. Vitetta, PhD, A. John Barrett, MD

Blood (2005) 106 (11): 595.

https://doi.org/10.1182/blood.V106.11.595.595

Published: 2005

Journal Articles

Pilot Clinical Trial of Adoptive Immunotherapy with Chimeric, Co-Stimulated Tumor-Infiltrating Lymphocytes after Allogeneic Hematopoietic Stem Cell Transplantation.

Nancy M. Hardy, MD, Vicki Fellowes, Jacopo Mariotti, MD, Charles Carter, Carl June4, MD, Bruce L. Levine4, PhD, Frances Hakim, PhD, Robert Vonderheide4, MD, DPhil, Ronald Gress, MD, Elizabeth J. Read, MD, Daniel Fowler, MD, Michael R. Bishop, MD

Blood (2005) 106 (11): 5407.

https://doi.org/10.1182/blood.V106.11.5407.5407

Published: 2005

Journal Articles

Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

Scott R. Solomon, Stephan Mielke, Bipin N. Savani, Aldemar Montero, Laura Wisch, Richard Childs, Nancy Hensel, John Schindler, Victor Ghetie, Susan F. Leitman, Thao Mai, Charles S. Carter, Roger Kurlander, Elizabeth J. Read, Ellen S. Vitetta, A. John Barrett

Blood (2005) 106 (3): 1123–1129.

https://doi.org/10.1182/blood-2005-01-0393

Published: 2005

Journal Articles

Evaluation of Three Different Cyclosporine-Based Graft Versus Host Disease (GVHD) Prophylaxis Regimens Following Nonmyeloablative Hematopoietic Stem Cell Transplantation (NST).

Ramaprasad Srinivasan, MD, PhD, Nancy Geller, PhD, Sakti Chakrabarti, MD, Igor Espinoza-Delgado, MD, Teresa Donohue, Susan Leitman, MD, Charles D. Bolan, MD, Elizabeth J. Read, MD, John A. Barrett, MD, Richard W. Childs, MD

Blood (2004) 104 (11): 1236.

https://doi.org/10.1182/blood.V104.11.1236.1236

Published: 2004

Journal Articles

Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI

Ali S. Arbab, Gene T. Yocum, Heather Kalish, Elaine K. Jordan, Stasia A. Anderson, Aarif Y. Khakoo, Elizabeth J. Read, Joseph A. Frank

Blood (2004) 104 (4): 1217–1223.

https://doi.org/10.1182/blood-2004-02-0655

Published: 2004

Journal Articles

High-dose cyclophosphamide with autologous lymphocyte–depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia

Richard D. Huhn, Patrick F. Fogarty, Ryotaro Nakamura, Elizabeth J. Read, Susan F. Leitman, Margaret E. Rick, Janice Kimball, Adeira Greene, Kristin Hansmann, Alois Gratwohl, Neal Young, A. John Barrett, Cynthia E. Dunbar

Blood (2003) 101 (1): 71–77.

https://doi.org/10.1182/blood-2001-12-0171

Published: 2003

Journal Articles

Mobilization, collection, and processing of peripheral blood stem cells in individuals with sickle cell trait

Elizabeth M. Kang, Ellen M. Areman, Virginia David-Ocampo, Courtney Fitzhugh, Mary E. Link, Elizabeth J. Read, Susan F. Leitman, Griffin P. Rodgers, John F. Tisdale

Blood (2002) 99 (3): 850–855.

https://doi.org/10.1182/blood.V99.3.850

Published: 2002

Journal Articles

Prolonged CD4 depletion after sequential autologous peripheral blood progenitor cell infusions in children and young adults

Crystal L. Mackall, Dagmar Stein, Thomas A. Fleisher, Margaret R. Brown, Frances T. Hakim, Catherine V. Bare, Susan F. Leitman, Elizabeth J. Read, Charles S. Carter, Leonard H. Wexler, Ronald E. Gress

Blood (2000) 96 (2): 754–762.

https://doi.org/10.1182/blood.V96.2.754

Published: 2000

Journal Articles

Engraftment of MDR1 and NeoR Gene-Transduced Hematopoietic Cells After Breast Cancer Chemotherapy

Jeffrey A. Moscow, Hui Huang, Charles Carter, Kenneth Hines, JoAnne Zujewski, Georgie Cusack, Cathy Chow, David Venzon, Brian Sorrentino, Yawen Chiang, Barry Goldspiel, Susan Leitman, Elizabeth J. Read, Andrea Abati, Michael M. Gottesman, Ira Pastan, Stephanie Sellers, Cynthia Dunbar, Kenneth H. Cowan

Blood (1999) 94 (1): 52–61.

https://doi.org/10.1182/blood.V94.1.52.413k35_52_61

Published: 1999

NARROW

Preclinical Studies for Sickle Cell Disease Gene Therapy Using Bone Marrow CD34+ Cells Modified with a βAS3-Globin Lentiviral Vector

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Successful Translation of a GMP-Based, Clinical Scale Selective Allodepletion Approach for Matched Donor-Recipient Pairs from Bench-to-Bedside.

Reconstitution of FOXP3 + regulatory T cells (T regs ) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease

Prolonging the Incubation of Monocytes with GM-CSF and IL-4 for More Than 3 Days during the Generation of Dendritic Cells (DCS) In Vitro Markedly Diminishes IL-12 and Increases IL-10 Production When DCS Are Subsequently Matured.

Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts Preserves a CD25− CD4+foxp3+ Fraction of T Cells and Thereby Provides a Source for Efficient Reconstitution of Regulatory T Cells and Additional GVHD Control.

Total Lymphocyte and Natural Killer (NK) Cell Count Day 30 Post-Transplant Strongly Predict Transplant Outcome after T Cell Depleted Allogeneic Stem Cell Transplantation.

High Efficiency Clinical Scale Selective Depletion of Alloreacting T Cells Using Expanded T Lymphocytes as Antigen-Presenting Cells and a TH9402-Based Photodepletion Technique in HLA-Mismatched and Matched Donor-Recipient Pairs.

Factors associated with early molecular remission after T cell-depleted allogeneic stem cell transplantation for chronic myelogenous leukemia

Reconstitution of Regulatory T Cells after Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts and Association with Acute Graft-Versus-Host-Disease.

Pilot Clinical Trial of Adoptive Immunotherapy with Chimeric, Co-Stimulated Tumor-Infiltrating Lymphocytes after Allogeneic Hematopoietic Stem Cell Transplantation.

Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

Evaluation of Three Different Cyclosporine-Based Graft Versus Host Disease (GVHD) Prophylaxis Regimens Following Nonmyeloablative Hematopoietic Stem Cell Transplantation (NST).

Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI

High-dose cyclophosphamide with autologous lymphocyte–depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia

Mobilization, collection, and processing of peripheral blood stem cells in individuals with sickle cell trait

Prolonged CD4 depletion after sequential autologous peripheral blood progenitor cell infusions in children and young adults

Engraftment of MDR1 and NeoR Gene-Transduced Hematopoietic Cells After Breast Cancer Chemotherapy

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American Society of Hematology

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ASH Publications

American Society of Hematology

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