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Journal Articles

Photodepletion differentially affects CD4 + Tregs versus CD4 + effector T cells from patients with chronic graft-versus-host disease

Clinical Trials & Observations
Jean-Philippe Bastien, Gorazd Krosl, Cynthia Therien, Marissa Rashkovan, Christian Scotto, Sandra Cohen, David S. Allan, Donna Hogge, R. Maarten Egeler, Claude Perreault, Denis Claude Roy
Journal: Blood
Blood (2010) 116 (23): 4859–4869.
https://doi.org/10.1182/blood-2010-03-273193
Published: 2010
Includes: Supplemental data
Journal Articles

Novel Photodepletion Strategy to Preserve and Expand Tregs While Eliminating CD4+ Effector T Cells From Patients with Chronic Graft-Versus-Host Disease

Jean-Philippe Bastien, MSc, Gorazd Krosl, Ph.D, Cynthia Therien, BSc, MSc, Marissa Rashkovan, B.Sc, Christian Scotto, Ph.D, Sandra Cohen, MD, David S. Allan, MD, MSc, Donna E. Hogge, MD, PhD, R. Maarten Egeler, MD, Claude Perreault, MD, Denis-Claude Roy, MD
Journal: Blood
Blood (2010) 116 (21): 353.
https://doi.org/10.1182/blood.V116.21.353.353
Published: 2010
Journal Articles

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Stephan Mielke, Raquel Nunes, Katayoun Rezvani, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, Yong Fan, Emma Gostick, David A. Price, Christian Scotto, Elizabeth J. Read, A. John Barrett
Journal: Blood
Blood (2008) 111 (8): 4392–4402.
https://doi.org/10.1182/blood-2007-08-104471
Published: 2008
Includes: Supplemental data
Journal Articles

Successful Translation of a GMP-Based, Clinical Scale Selective Allodepletion Approach for Matched Donor-Recipient Pairs from Bench-to-Bedside.

Stephan Mielke, MD, Raquel Nunes, MD, Katayoun Rezvani, MD, PhD, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, MD, Yong Fan, MD, Christian Scotto, PhD, Elizabeth J. Read, MD, A. John Barrett, MD
Journal: Blood
Blood (2007) 110 (11): 3279.
https://doi.org/10.1182/blood.V110.11.3279.3279
Published: 2007
Journal Articles

Anti-Chronic Graft Versus Host Disease Activity Though a Regulatory T Cell Dependent Mechanism after Photodynamic Therapy.

Jean-Philippe Bastien, Gorazd Krosl, Pascale Dube, Cynthia Therien, Christian Scotto, Denis-Claude Roy
Journal: Blood
Blood (2007) 110 (11): 3280.
https://doi.org/10.1182/blood.V110.11.3280.3280
Published: 2007
Journal Articles

High Efficiency Clinical Scale Selective Depletion of Alloreacting T Cells Using Expanded T Lymphocytes as Antigen-Presenting Cells and a TH9402-Based Photodepletion Technique in HLA-Mismatched and Matched Donor-Recipient Pairs.

Stephan Mielke, MD, Raquel Nunes, MD, Katayoun Rezvani, MD, PhD, Vicki S. Fellowes, Yong Fan, MD, Scott R. Solomon, MD, Christian Scotto, PhD, Elizabeth J. Read, MD, A. John Barrett, MD
Journal: Blood
Blood (2006) 108 (11): 721.
https://doi.org/10.1182/blood.V108.11.721.721
Published: 2006
Journal Articles

Control of Cell Death Levels Using Th9402-Based PDT Treatment on Fresh PBMC, and Potential Application to Patients with cGvHD.

Annie Levesque, MSc, Ann-Louise Savard, Denis-Claude Roy, PhD, Francine Foss, PhD, Christian Scotto, PhD
Journal: Blood
Blood (2005) 106 (11): 5258.
https://doi.org/10.1182/blood.V106.11.5258.5258
Published: 2005
Journal Articles

Potential TH9402-Based ECP Treatment for cGvHD Patients.

Annie Levesque, M.Sc, Ann-Louise Savard, Denis-Claude Roy, MD, Francine Foss, MD, Christian Scotto, Ph.D
Journal: Blood
Blood (2004) 104 (11): 5119.
https://doi.org/10.1182/blood.V104.11.5119.5119
Published: 2004