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Journal Articles

Immune Tolerance Induction to Factor IX Through B Cell Gene Transfer – Delineating Between Tolerogenic and Immunogenic B Cells.

Xiaomei Wang, PhD, Babak Moghimi, MD, Irene Zolotukhin, M.S., Ou Cao, MD, PhD, Roland W Herzog, PhD
Journal: Blood
Blood (2012) 120 (21): 3156.
https://doi.org/10.1182/blood.V120.21.3156.3156
Published: 2012
Journal Articles

Tolerance Induction to B Domain-Deleted and Full-Length F.VIII by Co-Administration with Rapamycin

Babak Moghimi, MD, Brandon Sack, Ou Cao, MD, PhD, Roland W Herzog, PhD
Journal: Blood
Blood (2010) 116 (21): 21.
https://doi.org/10.1182/blood.V116.21.21.21
Published: 2010
Journal Articles

A Prophylactic Protocol for the Prevention of Inhibitor Formation in Gene Therapy for Hemophilia B by Shifting the Balance from An Effector to a Regulatory T Cell Response

Sushrusha Nayak, MS, Brad Hoffman, PhD, Mario Cooper, BS, Mark Atkinson, PhD, Ou Cao, MD/PhD, Roland W. Herzog, PhD
Journal: Blood
Blood (2008) 112 (11): 3531.
https://doi.org/10.1182/blood.V112.11.3531.3531
Published: 2008
Journal Articles

TLR3 signaling does not affect organ-specific immune responses to factor IX in AAV gene therapy

Ou Cao, Roland W. Herzog
Journal: Blood
Blood (2008) 112 (3): 910–911.
https://doi.org/10.1182/blood-2008-02-137992
Published: 2008
Journal Articles

Induction and role of regulatory CD4 + CD25 + T cells in tolerance to the transgene product following hepatic in vivo gene transfer

Ou Cao, Eric Dobrzynski, Lixin Wang, Sushrusha Nayak, Bethany Mingle, Cox Terhorst, Roland W. Herzog
Journal: Blood
Blood (2007) 110 (4): 1132–1140.
https://doi.org/10.1182/blood-2007-02-073304
Published: 2007
Journal Articles

Regulatory CD4+CD25+ T Cells Are Required for Tolerance Induction to Factor IX by In Vivo Gene Transfer.

Ou Cao, MD, PhD, Lixin Wang, PhD, Sushrusha Nayak, BS, Roland W. Herzog, PhD
Journal: Blood
Blood (2006) 108 (11): 452.
https://doi.org/10.1182/blood.V108.11.452.452
Published: 2006
Journal Articles

Immune deviation by mucosal antigen administration suppresses gene-transfer–induced inhibitor formation to factor IX

Ou Cao, Elina Armstrong, Alexander Schlachterman, Lixin Wang, David K. Okita, Bianca Conti-Fine, Katherine A. High, Roland W. Herzog
Journal: Blood
Blood (2006) 108 (2): 480–486.
https://doi.org/10.1182/blood-2005-11-4668
Published: 2006
Journal Articles

Suppression of Inhibitor Formation to F.IX in Gene Transfer through Immune Deviation Induced by Mucosal Peptide Administration.

Ou Cao, MD, PhD, Elina Armstrong, MD, PhD, B. M. Conti-Fine, MD, Katherine A. High, MD, Roland W. Herzog, PhD
Journal: Blood
Blood (2005) 106 (11): 211.
https://doi.org/10.1182/blood.V106.11.211.211
Published: 2005
Journal Articles

Systemic protein delivery by muscle-gene transfer is limited by a local immune response

Lixin Wang, Eric Dobrzynski, Alexander Schlachterman, Ou Cao, Roland W. Herzog
Journal: Blood
Blood (2005) 105 (11): 4226–4234.
https://doi.org/10.1182/blood-2004-03-0848
Published: 2005
Journal Articles

Induction of antigen-specific CD4 + T-cell anergy and deletion by in vivo viral gene transfer

Eric Dobrzynski, Federico Mingozzi, Yi-Lin Liu, Elisabeth Bendo, Ou Cao, Lixin Wang, Roland W. Herzog
Journal: Blood
Blood (2004) 104 (4): 969–977.
https://doi.org/10.1182/blood-2004-03-0847
Published: 2004