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Journal Articles

Assessing the potential for AAV vector genotoxicity in a murine model

Hojun Li, Nirav Malani, Shari R. Hamilton, Alexander Schlachterman, Giulio Bussadori, Shyrie E. Edmonson, Rachel Shah, Valder R. Arruda, Federico Mingozzi, J. Fraser Wright, Frederic D. Bushman, Katherine A. High

Blood (2011) 117 (12): 3311–3319.

https://doi.org/10.1182/blood-2010-08-302729

Published: 2011

Includes: Supplemental data

Journal Articles

Assessment of Insertional Mutagenesis Risk Following AAV Vector-Mediated Factor IX Gene Transfer in Mice.

Hojun Li, Nirav Malani, Shari R Hamilton, DVM, Alexander Schlachterman, MD, Jim Z Zhang, PhD, Giulio Bussadori, Shyrie A Edmonson, Federico Mingozzi, PhD, J. Fraser Wright, PhD, Valder R. Arruda, MD, PhD, Frederic D Bushman, PhD, Katherine A. High, MD

Blood (2009) 114 (22): 2465.

https://doi.org/10.1182/blood.V114.22.2465.2465

Published: 2009

Journal Articles

Factor Xa Variants as Novel Bypass Agents for the Treatment of Hemophilia in Murine Models

Lacramioara Ivanciu, Ph.D., Raffaella Toso, Ph.D., Alexander Schlachterman, M.D., Harre Downey, B.S., Jian-Hua Liu, B.S., Valder R. Arruda, M.D., Ph.D., Rodney M. Camire, Ph.D.

Blood (2008) 112 (11): 239.

https://doi.org/10.1182/blood.V112.11.239.239

Published: 2008

Journal Articles

Differences in the Anticoagulant Activity of Murine and Human Activated Protein C (APC) in Mouse Thrombosis Models.

Christian Furlan Freguia, Joerg Schuettrumpf, Stefano Baila, Alexander Schlachterman, Jianxang Zou, Shangzhen Zhou, Valder R. Arruda

Blood (2006) 108 (11): 1471.

https://doi.org/10.1182/blood.V108.11.1471.1471

Published: 2006

Journal Articles

Immune deviation by mucosal antigen administration suppresses gene-transfer–induced inhibitor formation to factor IX

Ou Cao, Elina Armstrong, Alexander Schlachterman, Lixin Wang, David K. Okita, Bianca Conti-Fine, Katherine A. High, Roland W. Herzog

Blood (2006) 108 (2): 480–486.

https://doi.org/10.1182/blood-2005-11-4668

Published: 2006

Journal Articles

Assessing the Role of Continuous Activated Protein C (APC) Expression in Murine Thrombosis Models.

Joerg Schuettrumpf, MD, Alexander Schlachterman, Jianxiang Zou, PhD, Christian Furlan Freguia, Stefano Baila, Valder R. Arruda, MD

Blood (2005) 106 (11): 1030.

https://doi.org/10.1182/blood.V106.11.1030.1030

Published: 2005

Journal Articles

Systemic protein delivery by muscle-gene transfer is limited by a local immune response

Lixin Wang, Eric Dobrzynski, Alexander Schlachterman, Ou Cao, Roland W. Herzog

Blood (2005) 105 (11): 4226–4234.

https://doi.org/10.1182/blood-2004-03-0848

Published: 2005

Journal Articles

Factor IX variants improve gene therapy efficacy for hemophilia B

Joerg Schuettrumpf, Roland W. Herzog, Alexander Schlachterman, Antje Kaufhold, Darrel W. Stafford, Valder R. Arruda

Blood (2005) 105 (6): 2316–2323.

https://doi.org/10.1182/blood-2004-08-2990

Published: 2005

Journal Articles

Generation of Transgenic Mice Expressing High Levels of Activated Murine Coagulation Factor VII.

Majed N. Aljamali, PhD, Paris Margaritis, PhD, Alexander Schlachterman, B.S., Katherine A. High, MD

Blood (2004) 104 (11): 5253.

https://doi.org/10.1182/blood.V104.11.5253.5253

Published: 2004

Journal Articles

A Novel Role of Coagulation Proteases on Viral-Based Gene Transfer Efficacy.

Joerg Schuettrumpf, MD, Jianxiang Zou, PhD, Shin Jen Tai, Alexander Schlachterman, Kian Tian, Shyrie Edmonson, Jianhua Liu, Patricia Andrade-Gordon, MD, Katherine High, MD, Valder Arruda, MD

Blood (2004) 104 (11): 691.

https://doi.org/10.1182/blood.V104.11.691.691

Published: 2004

Journal Articles

In Vivo Evidence of Modulation of the Hemophilia Phenotype by the Factor V Leiden.

Alexander Schlachterman, Jianhua Liu, Yi-Lin Liu, Katherine High, MD, Valder Arruda, MD, PhD

Blood (2004) 104 (11): 693.

https://doi.org/10.1182/blood.V104.11.693.693

Published: 2004

Journal Articles

A Novel Deletion in the Fviii B-Domain That Reduces Transgene Size While Preserving FVIII Activity.

Yi-Lin Liu, MS, Hua Zhu, BS, Alexander Schlachterman, BA, Heesoon Chang, PhD, Rodney M. Camire, PhD, Katherine A. High, MD

Blood (2004) 104 (11): 3182.

https://doi.org/10.1182/blood.V104.11.3182.3182

Published: 2004

Journal Articles

Assessing Hemostatic Efficacy of Continuous Expression of Factor VIIa Following Administration of AAV Vectors into Hemophilia B Mice.

Alexander Schlachterman, B.A., Jianhua Liu, Majed Aljamali, Ph.D., Valder R. Arruda, M.D., Ph.D., Katherine A. High, M.D.

Blood (2004) 104 (11): 3184.

https://doi.org/10.1182/blood.V104.11.3184.3184

Published: 2004

NARROW

Assessing the potential for AAV vector genotoxicity in a murine model

Assessment of Insertional Mutagenesis Risk Following AAV Vector-Mediated Factor IX Gene Transfer in Mice.

Factor Xa Variants as Novel Bypass Agents for the Treatment of Hemophilia in Murine Models

Differences in the Anticoagulant Activity of Murine and Human Activated Protein C (APC) in Mouse Thrombosis Models.

Immune deviation by mucosal antigen administration suppresses gene-transfer–induced inhibitor formation to factor IX

Assessing the Role of Continuous Activated Protein C (APC) Expression in Murine Thrombosis Models.

Systemic protein delivery by muscle-gene transfer is limited by a local immune response

Factor IX variants improve gene therapy efficacy for hemophilia B

Generation of Transgenic Mice Expressing High Levels of Activated Murine Coagulation Factor VII.

A Novel Role of Coagulation Proteases on Viral-Based Gene Transfer Efficacy.

In Vivo Evidence of Modulation of the Hemophilia Phenotype by the Factor V Leiden.

A Novel Deletion in the Fviii B-Domain That Reduces Transgene Size While Preserving FVIII Activity.

Assessing Hemostatic Efficacy of Continuous Expression of Factor VIIa Following Administration of AAV Vectors into Hemophilia B Mice.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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