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Issue Archive

Volume 6, Issue 16
August 23 2022
Blood Advances Cover Image for Volume 6, Issue 16

Table of Contents

DRUG ADVANCES

The odyssey of pacritinib in myelofibrosis
Sangeetha Venugopal,John Mascarenhas
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SYSTEMATIC REVIEW

ICH in primary or metastatic brain cancer patients with or without anticoagulant treatment: a systematic review and meta-analysis
Michela Giustozzi,Giulia Proietti,Cecilia Becattini,Fausto Roila,Giancarlo Agnelli,Mario Mandalà
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CLINICAL TRIALS AND OBSERVATIONS

Reduced-dose WBRT as consolidation treatment for patients with primary CNS lymphoma: an LOC network study
Clinical Trials & Observations
Paul Lesueur,Gandhi Damaj,Khê Hoang-Xuan,Virginie Roland,Anna Schmitt,Olivier Chinot,Michel Fabbro,Philippe Agapé,Cécile Moluçon-Chabrot,Safia Chebrek,Agusti Alentorn,Loic Feuvret,Daniel Delgadillo,Dinu Stefan,Sylvain Choquet,Lucia Nichelli,Karima Mokhtari,Bertrand Mathon,Sylvain Dureau,Carole Soussain,Caroline Houillier
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

Siltuximab is associated with improved progression-free survival in idiopathic multicentric Castleman disease
Frits van Rhee,Adam Rosenthal,Karan Kanhai,Rabecka Martin,Katherine Nishimura,Antje Hoering,David C. Fajgenbaum
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Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis
Fotini Vogiatzi,Julia Heymann,Kristina Müller,Dorothee Winterberg,Aneta Drakul,Thies Rösner,Lennart Lenk,Michelle Heib,Carina Lynn Gehlert,Gunnar Cario,Martin Schrappe,Alexander Claviez,Beat Bornhauser,Jean-Pierre Bourquin,Simon Bomken,Dieter Adam,Fabian-Simon Frielitz,Britta Maecker-Kolhoff,Martin Stanulla,Thomas Valerius,Matthias Peipp,Christian Kellner,Denis M. Schewe
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Dominant epitopes presented by prevalent HLA alleles permit wide use of banked CMVpp65 T cells in adoptive therapy
Aisha N. Hasan,Ekaterina Doubrovina,Rosa Sottile,Susan Prockop,Martin G. Klatt,Glenn Heller,Annamalai Selvakumar,Lorna Barnett,Katharine C. Hsu,Richard J. O’Reilly
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LYMPHOID NEOPLASIA

A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile
Julia Salmeron-Villalobos,Caoimhe Egan,Vanessa Borgmann,Inga Müller,Blanca Gonzalez-Farre,Joan Enric Ramis-Zaldivar,Dominik Nann,Olga Balagué,Mónica López-Guerra,Dolors Colomer,Ilske Oschlies,Wolfram Klapper,Selina Glaser,Young Hyeh Ko,Irina Bonzheim,Reiner Siebert,Falko Fend,Stefania Pittaluga,Elias Campo,Itziar Salaverria,Elaine S. Jaffe,Leticia Quintanilla-Martinez
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Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma
Anthony R. Colombo,Monirath Hav,Mohan Singh,Alexander Xu,Alicia Gamboa,Tucker Lemos,Erik Gerdtsson,Denaly Chen,Jane Houldsworth,Rita Shaknovich,Tomohiro Aoki,Lauren Chong,Katsuyoshi Takata,Elizabeth A. Chavez,Christian Steidl,James Hicks,Peter Kuhn,Imran Siddiqi,Akil Merchant
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Nurselike cells sequester B cells in disorganized lymph nodes in chronic lymphocytic leukemia via alternative production of CCL21
Rim Zaaboub,Lene Vimeux,Vincent Contremoulins,Florence Cymbalista,Vincent Lévy,Emmanuel Donnadieu,Nadine Varin-Blank,Antoine Martin,Elisabetta Dondi
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Comparative efficacy and tolerability of novel agents vs chemotherapy in relapsed and refractory T-cell lymphomas: a meta-analysis
Nazila Shafagati,Min J. Koh,Leora Boussi,Hyun J. Park,Robert Stuver,Paul Bain,Francine M. Foss,Changyu Shen,Salvia Jain
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Low incidence of invasive fungal disease following CD19 chimeric antigen receptor T-cell therapy for non-Hodgkin lymphoma
Jessica S. Little,Muneerah M. Aleissa,Katherine Beluch,Isabel H. Gonzalez-Bocco,Francisco M. Marty,Jennifer Manne-Goehler,Sophia Koo,Sarah P. Hammond,Caron A. Jacobson
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MYELOID NEOPLASIA

HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition
Céline Moison,Jean-François Spinella,Jalila Chagraoui,Vincent-Philippe Lavallée,Bernhard Lehnertz,Clarisse Thiollier,Isabel Boivin,Nadine Mayotte,Tara MacRae,Anne Marinier,Josée Hébert,Guy Sauvageau
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PLATELETS AND THROMBOPOIESIS

Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans
Dmitri V. Gnatenko,Zhaoyan Liu,Patrick Hearing,Sook-Young Sohn,Yetao Hu,Anna Falanga,Song Wu,Lisa E. Malone,Wei Zhu,Wadie F. Bahou
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THROMBOSIS AND HEMOSTASIS

Traumatic vessel injuries initiating hemostasis generate high shear conditions
Alexandra A. Yakusheva,Kirill R. Butov,Georgii A. Bykov,Gábor Závodszky,Anita Eckly,Fazly I. Ataullakhanov,Christian Gachet,Mikhail A. Panteleev,Pierre H. Mangin
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TRANSPLANTATION

Prospective external validation of biomarkers to predict acute graft-versus-host disease severity
Clinical Trials & Observations
Marie Robin,Raphael Porcher,David Michonneau,Laetitia Taurines,Flore Sicre de Fontbrune,Aliénor Xhaard,Bastien Oriano,Aurélien Sutra Del Galy,Régis Peffault de Latour,Gérard Socié,Marie-Hélène Schlageter
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ICOS immunoPET enables visualization of activated T cells and early diagnosis of murine acute gastrointestinal GvHD
Zunyu Xiao,Israt S. Alam,Federico Simonetta,Weiyu Chen,Lukas Scheller,Surya Murty,Juliane K. Lohmeyer,Teresa L. Ramos,Michelle L. James,Robert S. Negrin,Sanjiv S. Gambhir
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RESEARCH LETTERS

The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS
Isabel Juliana F. Hofman,Teresa Mortera-Blanco,Pedro Luis Moura,Johanna Vestlund,Sigita Venckute Larsson,Edda M. Elvarsdottir,Gunilla Walldin,Magnus Tobiasson,Birgitta Sander,Marios Dimitriou,Sten-Eirik W. Jacobsen,Petter S. Woll,Martin Jädersten,Eva Hellström-Lindberg
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CD34+-selected stem cell boost can safely improve cytopenias following CAR T-cell therapy
Khushnuma Mullanfiroze,Arina Lazareva,Jan Chu,Lindsey Williams,Saskia Burridge,Juliana Silva,Robert Chiesa,Kanchan Rao,Giovanna Lucchini,Sara Ghorashian,Maeve O’Reilly,Ben Carpenter,Victoria Grandage,Rachael Hough,Claire Roddie,Persis J. Amrolia
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Safety and feasibility of stem cell boost as a salvage therapy for severe hematotoxicity after CD19 CAR T-cell therapy
Kai Rejeski,Andreas Burchert,Gloria Iacoboni,Pierre Sesques,Lars Fransecky,Veit Bücklein,Corinna Trenker,Rafael Hernani,Ralph Naumann,Jonas Schäfer,Viktoria Blumenberg,Christian Schmidt,Kristina Sohlbach,Michael von Bergwelt-Baildon,Emmanuel Bachy,Pere Barba,Marion Subklewe
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Rural-urban disparities in place of death in hematologic malignancies in the United States, 2003 to 2019
S. M. Qasim Hussaini,Amanda L. Blackford,Arjun Gupta,Ramy Sedhom,Sarah H. Cross,Haider J. Warraich,Thomas W. LeBlanc
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Loncastuximab tesirine in relapsed/refractory high-grade B-cell lymphoma: a subgroup analysis from the LOTIS-2 study
Clinical Trials & Observations
Juan P. Alderuccio,Weiyun Z. Ai,John Radford,Melhem Solh,Kirit M. Ardeshna,Matthew A. Lunning,Brian T. Hess,Pier L. Zinzani,Anastasios Stathis,Carmelo Carlo-Stella,Mehdi Hamadani,Brad S. Kahl,David Ungar,Turk Kilavuz,Eric Yu,Yajuan Qin,Paolo F. Caimi
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Sexual violence as a precipitator of chronic pain in young adults with sickle cell disease
Maya Chopra,Jeannie Byrd,Kristin Wuichet,Michael R. DeBaun
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Cellular distribution of mutations and association with disease risk in Langerhans cell histiocytosis without BRAFV600E
Clinical Trials & Observations
Paul Milne,Harshal Abhyankar,Brooks Scull,Preeti Singh,Rikhia Chakraborty,Carl E. Allen,Matthew Collin
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COMMENTARIES

Emerging clinical trial designs may accelerate translation in hematology: lessons from COVID-19
Clinical Trials & Observations
Matthew D. Neal,Patrick R. Lawler,Ryan Zarychanski
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Revision of RUNX1 variant curation rules
Simone Feurstein,Xi Luo,Mancy Shah,Taylor Walker,Nikita Mehta,David Wu,Lucy A. Godley,on behalf of the Myeloid Malignancy Variant Curation Expert Panel
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Long-term safety for patients with tisagenlecleucel-treated relapsed/refractory diffuse large B-cell lymphoma
Clinical Trials & Observations
Ulrich Jaeger,Constantine S. Tam,Peter Borchmann,Joseph P. McGuirk,Marianne Johansen,Edmund K. Waller,Samantha Jaglowski,Charalambos Andreadis,Stephen R. Foley,Jason R. Westin,Isabelle Fleury,P. Joy Ho,Stephan Mielke,Takanori Teshima,Gilles Salles,Stephen J. Schuster,Fiona He,Richard T. Maziarz,Sebastian Mayer,Shinichi Makita,Marie J. Kersten,Monalisa Ghosh,Nina Wagner-Johnston,Koji Kato,Paolo Corradini,Hideki Goto,Silvia Colicino,Abhijit Agarwal,Chiara Lobetti-Bodoni,Michael R. Bishop
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ERRATUM

Vo P, Gooley, TA, Carpenter PA, et al. Prediction of outcomes after second-line treatment for acute graft-versus-host disease. Blood Adv. 2022;6(11):3220-3229.
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All Issues

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Overcoming venetoclax resistance through heme-mediated NOXA/cyclin D1/Mcl-1 axis with a novel artemisinin conjugate

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