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Lennart Lenk
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Journal Articles

A brain organoid/ALL coculture model reveals the AP-1 pathway as critically associated with CNS involvement of BCP-ALL

Philip Gebing, Stefanos Loizou, Sebastian Hänsch, Julian Schliehe-Diecks, Lea Spory, Pawel Stachura, Vera H. Jepsen, Melina Vogt, Aleksandra A. Pandyra, Herui Wang, Zhengping Zhuang, Johannes Zimmermann, Martin Schrappe, Gunnar Cario, Ameera Alsadeq, Denis M. Schewe, Arndt Borkhardt, Lennart Lenk, Ute Fischer, Sanil Bhatia
Journal: Blood Advances
Blood Adv (2024) 8 (19): 4997–5011.
https://doi.org/10.1182/bloodadvances.2023011145
Published: 2024
Includes: Supplemental data
Journal Articles

Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1 + /preBCR + ALL

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W. Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C. Bassik, Michael L. Cleary, Oliver Schilling, Merja Heinäniemi, Jesús Duque-Afonso
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2846–2860.
https://doi.org/10.1182/bloodadvances.2023011582
Published: 2024
Includes: Supplemental data
Journal Articles

Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis

Fotini Vogiatzi, Julia Heymann, Kristina Müller, Dorothee Winterberg, Aneta Drakul, Thies Rösner, Lennart Lenk, Michelle Heib, Carina Lynn Gehlert, Gunnar Cario, Martin Schrappe, Alexander Claviez, Beat Bornhauser, Jean-Pierre Bourquin, Simon Bomken, Dieter Adam, Fabian-Simon Frielitz, Britta Maecker-Kolhoff, Martin Stanulla, Thomas Valerius, Matthias Peipp, Christian Kellner, Denis M. Schewe
Journal: Blood Advances
Blood Adv (2022) 6 (16): 4847–4858.
https://doi.org/10.1182/bloodadvances.2022007364
Published: 2022
Includes: Supplemental data
Journal Articles

Larotrectinib in TRK fusion–positive pediatric B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Denis M. Schewe, Lennart Lenk, Fotini Vogiatzi, Dorothee Winterberg, Annika V. Rademacher, Swantje Buchmann, Dahlia Henry, Anke K. Bergmann, Gunnar Cario, Michael C. Cox
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3499–3502.
https://doi.org/10.1182/bloodadvances.2019000700
Published: 2019
Includes: Supplemental data