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Gunnar Cario
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Journal Articles

A brain organoid/ALL coculture model reveals the AP-1 pathway as critically associated with CNS involvement of BCP-ALL

Philip Gebing, Stefanos Loizou, Sebastian Hänsch, Julian Schliehe-Diecks, Lea Spory, Pawel Stachura, Vera H. Jepsen, Melina Vogt, Aleksandra A. Pandyra, Herui Wang, Zhengping Zhuang, Johannes Zimmermann, Martin Schrappe, Gunnar Cario, Ameera Alsadeq, Denis M. Schewe, Arndt Borkhardt, Lennart Lenk, Ute Fischer, Sanil Bhatia
Journal: Blood Advances
Blood Adv (2024) 8 (19): 4997–5011.
https://doi.org/10.1182/bloodadvances.2023011145
Published: 2024
Includes: Supplemental data
Journal Articles

Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1 + /preBCR + ALL

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W. Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C. Bassik, Michael L. Cleary, Oliver Schilling, Merja Heinäniemi, Jesús Duque-Afonso
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2846–2860.
https://doi.org/10.1182/bloodadvances.2023011582
Published: 2024
Includes: Supplemental data
Journal Articles

CD19 CAR T cells are an effective therapy for posttransplant relapse in patients with B-lineage ALL: real-world data from Germany

Clinical Trials & Observations
Peter Bader, Claudia Rossig, Martin Hutter, Francis Ayuketang Ayuk, Claudia D. Baldus, Veit L. Bücklein, Halvard Bonig, Gunnar Cario, Hermann Einsele, Udo Holtick, Christian Koenecke, Shahrzad Bakhtiar, Annette Künkele, Roland Meisel, Fabian Müller, Ingo Müller, Olaf Penack, Eva Rettinger, Martin G. Sauer, Paul-Gerhardt Schlegel, Jan Soerensen, Arend von Stackelberg, Brigitte Strahm, Julia Hauer, Tobias Feuchtinger, Andrea Jarisch
Journal: Blood Advances
Blood Adv (2023) 7 (11): 2436–2448.
https://doi.org/10.1182/bloodadvances.2022008981
Published: 2023
Includes: Supplemental data
Journal Articles

Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis

Fotini Vogiatzi, Julia Heymann, Kristina Müller, Dorothee Winterberg, Aneta Drakul, Thies Rösner, Lennart Lenk, Michelle Heib, Carina Lynn Gehlert, Gunnar Cario, Martin Schrappe, Alexander Claviez, Beat Bornhauser, Jean-Pierre Bourquin, Simon Bomken, Dieter Adam, Fabian-Simon Frielitz, Britta Maecker-Kolhoff, Martin Stanulla, Thomas Valerius, Matthias Peipp, Christian Kellner, Denis M. Schewe
Journal: Blood Advances
Blood Adv (2022) 6 (16): 4847–4858.
https://doi.org/10.1182/bloodadvances.2022007364
Published: 2022
Includes: Supplemental data
Journal Articles

TNFR2 is required for RIP1-dependent cell death in human leukemia

Júlia Aguadé-Gorgorió, Scott McComb, Cornelia Eckert, Anna Guinot, Blerim Marovca, Caterina Mezzatesta, Silvia Jenni, Liridon Abduli, Martin Schrappe, Maria Pamela Dobay, Martin Stanulla, Arend von Stackelberg, Gunnar Cario, Jean-Pierre Bourquin, Beat C. Bornhauser
Journal: Blood Advances
Blood Adv (2020) 4 (19): 4823–4833.
https://doi.org/10.1182/bloodadvances.2019000796
Published: 2020
Includes: Supplemental data
Journal Articles

The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL

Beat Bornhauser, Gunnar Cario, Anna Rinaldi, Thomas Risch, Virginia Rodriguez Martinez, Moritz Schütte, Hans-Jörg Warnatz, Nastassja Scheidegger, Paulina Mirkowska, Martina Temperli, Claudia Möller, Angela Schumich, Michael Dworzak, Andishe Attarbaschi, Monika Brüggemann, Mathias Ritgen, Ester Mejstrikova, Andreas Hofmann, Barbara Buldini, Pamela Scarparo, Giuseppe Basso, Oscar Maglia, Giuseppe Gaipa, Tessa Lara Skroblyn, Quy A. Ngo, Geertruij te Kronnie, Elena Vendramini, Renate Panzer-Grümayer, Malwine Jeanette Barz, Blerim Marovca, Mathias Hauri-Hohl, Felix Niggli, Cornelia Eckert, Martin Schrappe, Martin Stanulla, Martin Zimmermann, Bernd Wollscheid, Marie-Laure Yaspo, Jean-Pierre Bourquin
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4052–4064.
https://doi.org/10.1182/bloodadvances.2019000938
Published: 2020
Includes: Supplemental data
Journal Articles

Larotrectinib in TRK fusion–positive pediatric B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Denis M. Schewe, Lennart Lenk, Fotini Vogiatzi, Dorothee Winterberg, Annika V. Rademacher, Swantje Buchmann, Dahlia Henry, Anke K. Bergmann, Gunnar Cario, Michael C. Cox
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3499–3502.
https://doi.org/10.1182/bloodadvances.2019000700
Published: 2019
Includes: Supplemental data