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Issue Archive

Volume 8, Issue 14
July 23 2024
Issue Cover

Table of Contents

INSIDE BLOOD ADVANCES

Aspiring to equity: race vs ethnicity in clinical research
Clinical Trials & Observations
Nada Hamad
View Articletitled, Aspiring to equity: race vs ethnicity in clinical research
Vitamin D insufficiency in CLL: a modifiable prognostic factor?
Sameer A. Parikh,Tait D. Shanafelt
View Articletitled, Vitamin D insufficiency in CLL: a modifiable prognostic factor?
Soiled soil
Clinical Trials & Observations
Frederick R. Appelbaum
View Articletitled, Soiled soil

REVIEW ARTICLE

Biological and clinical determinants shaping heterogeneity in mantle cell lymphoma
Cristina López,Elisabeth Silkenstedt,Martin Dreyling,Sílvia Beà
View Articletitled, Biological and clinical determinants shaping heterogeneity in mantle cell lymphoma

SYSTEMATIC REVIEW

Clonal hematopoiesis of indeterminate potential as a prognostic factor: a systematic review and meta-analysis
Clinical Trials & Observations
Jasmine Singh,Nancy Li,Elham Ashrafi,Le Thi Phuong Thao,David J. Curtis,Erica M. Wood,Zoe K. McQuilten
View Articletitled, Clonal hematopoiesis of indeterminate potential as a prognostic factor: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Treatment strategies and outcome in relapsed peripheral T-cell lymphoma: results from the Netherlands Cancer Registry
Clinical Trials & Observations
Mirian Brink,Francien Huisman,Frederik O. Meeuwes,Marjolein W. M. van der Poel,Marie José Kersten,Mariëlle Wondergem,Lara Böhmer,F. J. Sherida H. Woei-A-Jin,Otto Visser,Rimke Oostvogels,Patty M. Jansen,Arjan Diepstra,Tjeerd J. F. Snijders,Gerwin Huls,Joost S. P. Vermaat,Wouter J. Plattel,Marcel Nijland
View Articletitled, Treatment strategies and outcome in relapsed peripheral T-cell lymphoma: results from the Netherlands Cancer Registry
Supplemental data
Daratumumab, cyclophosphamide, bortezomib, and dexamethasone for transplant-ineligible myeloma: AMaRC 03-16
Clinical Trials & Observations
Peter Mollee,John Reynolds,Wojt Janowski,Hang Quach,Philip Campbell,Simon Gibbs,Sophie Lee,Edwin Lee,Kerry Taylor,Tara Cochrane,Craig Wallington-Gates,Fiona Kwok,Nicholas Weber,Ian Kerridge,Helen Weston,P. Joy Ho,Michael Francis Leahy,Noemi Horvath,Andrew Spencer
View Articletitled, Daratumumab, cyclophosphamide, bortezomib, and dexamethasone for transplant-ineligible myeloma: AMaRC 03-16
Supplemental data
Impact of patient demographics and neighborhood socioeconomic variables on clinical trial participation patterns for NHL
Clinical Trials & Observations
Chijioke Nze,Clark R. Andersen,Amy A. Ayers,Jason Westin,Michael Wang,Swaminathan Iyer,Sairah Ahmed,Chelsea Pinnix,Francisco Vega,Lynne Nguyen,Lorna McNeill,Loretta J. Nastoupil,Kehe Zhang,Cici X. Bauer,Christopher R. Flowers
View Articletitled, Impact of patient demographics and neighborhood socioeconomic variables on clinical trial participation patterns for NHL
Supplemental data

HEALTH SERVICES AND OUTCOMES

Costs and impact of disease in adults with sickle cell disease: a pilot study
Sophie Lanzkron,Nicole Crook,Joanne Wu,Sarah Hussain,Randall G. Curtis,Derek Robertson,Judith R. Baker,Diane Nugent,Amit Soni,Jonathan C. Roberts,Megan M. Ullman,Julie Kanter,Michael B. Nichol
View Articletitled, Costs and impact of disease in adults with sickle cell disease: a pilot study
Gaps during pediatric to adult care transfer escalate acute resource utilization in sickle cell disease
Kristen E. Howell,Mariam Kayle,Matthew P. Smeltzer,Vikki G. Nolan,Joacy G. Mathias,Marquita Nelson,Sheila Anderson,Jerlym S. Porter,Nirmish Shah,Jane S. Hankins
View Articletitled, Gaps during pediatric to adult care transfer escalate acute resource utilization in sickle cell disease
Supplemental data
Optimization of older adults by a geriatric assessment–guided multidisciplinary clinic before CAR T-cell therapy
Samuel J. Yates,John F. Cursio,Andrew Artz,Keriann Kordas,Michael R. Bishop,Benjamin A. Derman,Satyajit Kosuri,Peter A. Riedell,Justin Kline,Andrzej Jakubowiak,Mylove Mortel,Shalitha Johnson,Mariam T. Nawas
View Articletitled, Optimization of older adults by a geriatric assessment–guided multidisciplinary clinic before CAR T-cell therapy

HEMATOPOIESIS AND STEM CELLS

Recipient clonal hematopoiesis in allogeneic bone marrow transplantation for lymphoid malignancies
Philip H. Imus,Sergiu Pasca,Hua-Ling Tsai,Yosra M. Aljawai,Kenneth R. Cooke,Jeremy D. Walston,Christopher D. Gocke,Ravi Varadhan,Richard J. Jones,Lukasz P. Gondek
View Articletitled, Recipient clonal hematopoiesis in allogeneic bone marrow transplantation for lymphoid malignancies
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation
J. Brett Heimlich,Pawan Bhat,Alyssa C. Parker,Matthew T. Jenkins,Caitlyn Vlasschaert,Jessica Ulloa,Joseph C. Van Amburg,Chad R. Potts,Sydney Olson,Alexander J. Silver,Ayesha Ahmad,Brian Sharber,Donovan Brown,Ningning Hu,Peter van Galen,Michael R. Savona,Alexander G. Bick,P. Brent Ferrell
View Articletitled, Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation
Supplemental data
Geographic EBV variants confound disease-specific variant interpretation and predict variable immune therapy responses
Edward L. Briercheck,Shashidhar Ravishankar,Elshafa Hassan Ahmed,César Camilo Carías Alvarado,Juan Carlos Barrios Menéndez,Oscar Silva,Elizabeth Solórzano-Ortiz,Marcos Mauricio Siliézar Tala,Philip Stevenson,Yuexin Xu,Anthony Wilder Wohns,Daniel Enriquez-Vera,Carlos Barrionuevo,Shan-Chi Yu,Aharon G. Freud,Christopher Oakes,Christoph Weigel,David M. Weinstock,Haley L. Klimaszewski,Apollinaire Ngankeu,Nora Mutalima,Gabriela Samayoa-Reyes,Robert Newton,Rosemary Rochford,Fabiola Valvert,Yasodha Natkunam,Andrei Shustov,Robert A. Baiocchi,Edus H. Warren
View Articletitled, Geographic EBV variants confound disease-specific variant interpretation and predict variable immune therapy responses
Supplemental data
Incidence and outcomes of cytomegalovirus reactivation after chimeric antigen receptor T-cell therapy
Rick Y. Lin,Anthony D. Anderson,Yoichiro Natori,Mohammed Raja,Michele I. Morris,Antonio Jimenez Jimenez,Amer Beitinjaneh,Trent Wang,Mark Goodman,Lazaros Lekakis,Jay Spiegel,Noa G. Holtzman,Denise Pereira,Cara Benjamin,Akina Natori,Krishna V. Komanduri,Jose F. Camargo
View Articletitled, Incidence and outcomes of cytomegalovirus reactivation after chimeric antigen receptor T-cell therapy
Supplemental data

LYMPHOID NEOPLASIA

Flow cytometric profiles with CD7 and CADM1 in CD4+ T cells are promising indicators for prognosis of aggressive ATL
Clinical Trials & Observations
Koji Jimbo,Toyotaka Kawamata,Yoshihiro Inamoto,Ayumu Ito,Kazuaki Yokoyama,Aki Sato,Takahiro Fukuda,Kaoru Uchimaru,Yasuhito Nannya
View Articletitled, Flow cytometric profiles with CD7 and CADM1 in CD4<sup>+</sup> T cells are promising indicators for prognosis of aggressive ATL
Supplemental data
Vitamin D supplement for patients with early-stage chronic lymphocytic leukemia is associated with a longer time to first treatment
Tamar Tadmor,Guy Melamed,Hilel Alapi,Sivan Gazit,Tal Patalon,Lior Rokach
View Articletitled, Vitamin D supplement for patients with early-stage chronic lymphocytic leukemia is associated with a longer time to first treatment
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Nuclear receptor Rev-erbα role in fine-tuning erythropoietin gene expression
Sumit Kumar,Rashmi Arora,Shalini Gupta,Nancy Ahuja,Ella Bhagyaraj,Ravikanth Nanduri,Rashi Kalra,Asheesh Kumar Khare,Saumyata Kumawat,Vipashu Kaushal,Mahathi Sharma,Pawan Gupta
View Articletitled, Nuclear receptor Rev-erbα role in fine-tuning erythropoietin gene expression
Supplemental data
Physiologically based trimester-specific serum ferritin thresholds for iron deficiency in US pregnant women
Zuguo Mei,O. Yaw Addo,Maria Elena D. Jefferds,Rafael C. Flores-Ayala,Gary M. Brittenham
View Articletitled, Physiologically based trimester-specific serum ferritin thresholds for iron deficiency in US pregnant women
Supplemental data

THROMBOSIS AND HEMOSTASIS

Packaging of supplemented urokinase into alpha granules of in vitro–grown megakaryocytes for targeted nascent clot lysis
Mortimer Poncz,Sergei V. Zaitsev,Hyunsook Ahn,M. Anna Kowalska,Khalil Bdeir,Konstantin V. Dergilev,Lacramioara Ivanciu,Rodney M. Camire,Douglas B. Cines,Victoria Stepanova
View Articletitled, Packaging of supplemented urokinase into alpha granules of in vitro–grown megakaryocytes for targeted nascent clot lysis
Supplemental data

TRANSPLANTATION

Late cytomegalovirus disease after hematopoietic cell transplantation: significance of novel transplantation techniques
Alicja Sadowska-Klasa,Sezen Özkök,Hu Xie,Wendy Leisenring,Danniel Zamora,Sachiko Seo,Jordan Sheldon,Stephanie J. Lee,Keith R. Jerome,Margaret L. Green,Michael Boeckh
View Articletitled, Late cytomegalovirus disease after hematopoietic cell transplantation: significance of novel transplantation techniques
Supplemental data
Extracellular release of damaged mitochondria induced by prehematopoietic stem cell transplant conditioning exacerbates GVHD
Vijith Vijayan,Hao Yan,Juliane K. Lohmeyer,Kaylin A. Prentiss,Rachna V. Patil,Giulia Barbarito,Ivan Lopez,Aly Elezaby,Kolten Peterson,Jeanette Baker,Nicolai P. Ostberg,Alice Bertaina,Robert S. Negrin,Daria Mochly-Rosen,Kenneth Weinberg,Bereketeab Haileselassie
View Articletitled, Extracellular release of damaged mitochondria induced by prehematopoietic stem cell transplant conditioning exacerbates GVHD
Supplemental data

RESEARCH LETTERS

D-dimer for patients on VKA vs DOAC: impact on the validity of D-dimer to make decision for extended anticoagulation
Clinical Trials & Observations
Armando Tripodi,Marco Capecchi,Erica Scalambrino,Marigrazia Clerici,Barbara Scimeca,Pasquale Agosti,Paolo Bucciarelli,Flora Peyvandi
View Articletitled, D-dimer for patients on VKA vs DOAC: impact on the validity of D-dimer to make decision for extended anticoagulation
Predictive model for the risk of cytokine release syndrome with glofitamab treatment for diffuse large B-cell lymphoma
Clinical Trials & Observations
Giuseppe Gritti,Anton Belousov,James Relf,Mark Dixon,Maneesh Tandon,Krishna Komanduri
View Articletitled, Predictive model for the risk of cytokine release syndrome with glofitamab treatment for diffuse large B-cell lymphoma
Supplemental data
Neonatal NET-inhibitory factor inhibits macrophage extracellular trap formation
Joseph S. Bircher,Frederik Denorme,Mark J. Cody,Claudia V. de Araujo,Aaron C. Petrey,Elizabeth A. Middleton,Robert A. Campbell,Christian C. Yost
View Articletitled, Neonatal NET-inhibitory factor inhibits macrophage extracellular trap formation
Supplemental data
Recombinant ADAMTS13: an effective rescue therapy for acute cTTP during pregnancy
Simon Dadoun,Karolina Adam,Lisa Hensch,Theonia K. Boyd,Sami Ibrahimi,James N. George,Marie Scully,Senthil Sukumar
View Articletitled, Recombinant ADAMTS13: an effective rescue therapy for acute cTTP during pregnancy
A novel transmembrane CXCR4 variant that expands the WHIM genotype-phenotype paradigm
Katarina Zmajkovicova,Sumit Pawar,Svetlana O. Sharapova,Christoph B. Geier,Ivana Wiest,Chi Nguyen,Halenya Monticelli,Sabine Maier-Munsa,Kelly Chen,John W. Sleasman,Svetlana Aleshkevich,Ekaterina Polyakova,Inga Sakovich,Klaus Warnatz,Bodo Grimbacher,Michele Proietti,Neal Sondheimer,Boglarka Ujhazi,Sumai Gordon,Maryssa Ellison,Melis Yilmaz,Jolan E. Walter,Adriana Badarau,Arthur G. Taveras,Jadee L. Neff,Jacob R. Bledsoe,Teresa K. Tarrant
View Articletitled, A novel transmembrane <em>CXCR4</em> variant that expands the WHIM genotype-phenotype paradigm
Supplemental data

COMMENTARIES

Bringing global hematology research to the forefront
Global Advances
Andrés Gómez-De León,Andrés Noyola-Pérez,Lourdes Gil-Flores,Hemant Malhotra,Vasile Musteata,Amal El-Beshlawy,Hilman Tadjoedin,Carolina Pavlovsky,Jorge Cortes
View Articletitled, Bringing global hematology research to the forefront
Cardiovascular toxicity of Bruton tyrosine kinase inhibitors: forget about selectivity but watch the clock
Clinical Trials & Observations
Giorgio Minotti
View Articletitled, Cardiovascular toxicity of Bruton tyrosine kinase inhibitors: forget about selectivity but watch the clock
  • Cover Image

    Cover Image

    issue cover

    Image analysis demonstrates the effect of Rev-erbα modulation on hypoxia-inducible factor 2α dynamics within the cells. See the article by Kumar et al.

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