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Franco Locatelli
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Journal Articles

Antiviral potential of Vδ2 T-cells in children given TCR αβ/CD19 cell depleted HLA-haploidentical HSCT

Veronica Bordoni, Federica Guarracino, Federica Galaverna, Valentina Bertaina, Giuseppina Li Pira, Marco Rosichini, Angela Pitisci, Giulia Matusali, Fabrizio Maggi, Enrico Velardi, Pietro Merli, Franco Locatelli, Chiara Agrati
Journal: Blood Advances
Blood Adv bloodadvances.2024013902.
https://doi.org/10.1182/bloodadvances.2024013902
Published: 2024
Includes: Supplemental data
Journal Articles

COMPARABLE OUTCOMES AFTER BUSULFAN- OR TREOSULFAN-BASED CONDITIONING FOR ALLO-HSCT IN CHILDREN WITH ALL-RESULTS OF FORUM

Krzysztof Kałwak, Laura M. Moser, Ulrike Pötschger, Peter Bader, Katharina Kleinschmidt, Roland Meisel, Jean-Hugues Dalle, M. Akif Yeşilipek, Adriana Cristina Balduzzi, Gergely Kriván, Evgenios Goussetis, Raquel Staciuk, Petr Sedlacek, Herbert Pichler, Peter Svec, Melissa Gabriel, Tayfun Güngör, Ernest Bilic, Jochen Buechner, Marleen Renard, Kim Vettenranta, Marianne Ifversen, Cristina Diaz-de-Heredia, Jerry Stein, Jacek Toporski, Marc B Bierings, Christina Peters, Marc Ansari, Franco Locatelli
Journal: Blood Advances
Blood Adv bloodadvances.2024014548.
https://doi.org/10.1182/bloodadvances.2024014548
Published: 2024
Includes: Supplemental data
Journal Articles

Venetoclax: a new player in the treatment of children with high-risk myeloid malignancies?

Riccardo Masetti, Francesco Baccelli, Davide Leardini, Franco Locatelli
Journal: Blood Advances
Blood Adv (2024) 8 (13): 3583–3595.
https://doi.org/10.1182/bloodadvances.2023012041
Published: 2024
Journal Articles

Optimized cytogenetic risk-group stratification of KMT2A -rearranged pediatric acute myeloid leukemia

Romy E. van Weelderen, Christine J. Harrison, Kim Klein, Yilin Jiang, Jonas Abrahamsson, Todd Alonzo, Richard Aplenc, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Barbara Buldini, Barbara De Moerloose, Michael N. Dworzak, Sarah Elitzur, José M. Fernández Navarro, Alan Gamis, Robert B. Gerbing, Bianca F. Goemans, Hester A. de Groot-Kruseman, Erin Guest, Shau-Yin Ha, Henrik Hasle, Charikleia Kelaidi, Hélène Lapillonne, Guy Leverger, Franco Locatelli, Takako Miyamura, Ulrika Norén-Nyström, Sophia Polychronopoulou, Mareike Rasche, Jeffrey E. Rubnitz, Jan Stary, Anne Tierens, Daisuke Tomizawa, C. Michel Zwaan, Gertjan J. L. Kaspers
Journal: Blood Advances
Blood Adv (2024) 8 (12): 3200–3213.
https://doi.org/10.1182/bloodadvances.2023011771
Published: 2024
Includes: Supplemental data
Journal Articles

Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A :: AFF1 fusion

Caterina Tretti Parenzan, Anna Dal Molin, Giorgia Longo, Enrico Gaffo, Alessia Buratin, Alice Cani, Elena Boldrin, Valentina Serafin, Paola Guglielmelli, Alessandro M. Vannucchi, Giovanni Cazzaniga, Andrea Biondi, Franco Locatelli, Lueder H. Meyer, Barbara Buldini, Geertruij te Kronnie, Silvia Bresolin, Stefania Bortoluzzi
Journal: Blood Advances
Blood Adv (2024) 8 (5): 1305–1319.
https://doi.org/10.1182/bloodadvances.2023011291
Published: 2024
Includes: Supplemental data
Journal Articles

Low rate of nonrelapse mortality in under-4-year-olds with ALL given chemotherapeutic conditioning for HSCT: a phase 3 FORUM study

Clinical Trials & Observations
Peter Bader, Ulrike Pötschger, Jean-Hugues Dalle, Laura M. Moser, Adriana Balduzzi, Marc Ansari, Jochen Buechner, Tayfun Güngör, Marianne Ifversen, Gergely Krivan, Herbert Pichler, Marleen Renard, Raquel Staciuk, Petr Sedlacek, Jerry Stein, Jan Robert Heusel, Tony Truong, Jacek Wachowiak, Akif Yesilipek, Franco Locatelli, Christina Peters
Journal: Blood Advances
Blood Adv (2024) 8 (2): 416–428.
https://doi.org/10.1182/bloodadvances.2023010591
Published: 2024
Includes: Supplemental data
Journal Articles

Survival outcomes of children with relapsed or refractory myeloid leukemia associated with Down syndrome

Clinical Trials & Observations
Nikhil Raghuram, Daisuke Hasegawa, Kentaro Nakashima, Syaza Rahman, Evangelia Antoniou, Torjus Skajaa, Pietro Merli, Anupam Verma, Karen R. Rabin, Catherine Aftandilian, Rishi S. Kotecha, Daniel Cheuk, Kirsi Jahnukainen, Alexandra Kolenova, Walentyna Balwierz, Alice Norton, Maureen O’Brien, Sonia Cellot, Ashley Chopek, Nira Arad-Cohen, Bianca Goemans, Marta Rojas-Vasquez, Hany Ariffin, Jack Bartram, E. Anders Kolb, Franco Locatelli, Jan-Henning Klusmann, Henrik Hasle, Bryan McGuire, Afia Hasnain, Lillian Sung, Johann Hitzler
Journal: Blood Advances
Blood Adv (2023) 7 (21): 6532–6539.
https://doi.org/10.1182/bloodadvances.2022009381
Published: 2023
Includes: Supplemental data
Journal Articles

Venetoclax-based therapies in pediatric advanced MDS and relapsed/refractory AML: a multicenter retrospective analysis

Riccardo Masetti, Francesco Baccelli, Davide Leardini, Francesca Gottardi, Francesca Vendemini, Alessandro Di Gangi, Marco Becilli, Mariachiara Lodi, Manuela Tumino, Luca Vinci, Miriam Erlacher, Brigitte Strahm, Charlotte M. Niemeyer, Franco Locatelli
Journal: Blood Advances
Blood Adv (2023) 7 (16): 4366–4370.
https://doi.org/10.1182/bloodadvances.2023010113
Published: 2023
Includes: Supplemental data
Journal Articles

Long-term proliferation of immature hypoxia-dependent JMML cells supported by a 3D in vitro system

Alice Cani, Caterina Tretti Parenzan, Chiara Frasson, Elena Rampazzo, Pamela Scarparo, Samuela Francescato, Federico Caicci, Vito Barbieri, Antonio Rosato, Simone Cesaro, Marco Zecca, Concetta Micalizzi, Laura Sainati, Martina Pigazzi, Alessandra Biffi, Barbara Buldini, Franco Locatelli, Luca Persano, Riccardo Masetti, Geertruij te Kronnie, Silvia Bresolin
Journal: Blood Advances
Blood Adv (2023) 7 (8): 1513–1524.
https://doi.org/10.1182/bloodadvances.2021006746
Published: 2023
Includes: Supplemental data
Journal Articles

Hypodiploidy has unfavorable impact on survival in pediatric acute myeloid leukemia: an I-BFM Study Group collaboration

Anne Sofie Borg Hammer, Kristian Løvvik Juul-Dam, Julie Damgaard Sandahl, Jonas Abrahamsson, Malgorzata Czogala, Emmanuelle Delabesse, Iren Haltrich, Kirsi Jahnukainen, E. Anders Kolb, Gábor Kovács, Guy Leverger, Franco Locatelli, Riccardo Masetti, Ulrika Noren-Nyström, Susana C. Raimondi, Mareike Rasche, Dirk Reinhardt, Tomohiko Taki, Daisuke Tomizawa, Bernward Zeller, Henrik Hasle, Eigil Kjeldsen
Journal: Blood Advances
Blood Adv (2023) 7 (6): 1045–1055.
https://doi.org/10.1182/bloodadvances.2022008251
Published: 2023
Includes: Supplemental data
Journal Articles

Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1 -mutated AML

Clinical Trials & Observations
Giulia Pianigiani, Andrea Gagliardi, Federica Mezzasoma, Francesca Rocchio, Valentina Tini, Barbara Bigerna, Paolo Sportoletti, Simona Caruso, Andrea Marra, Sara Peruzzi, Eleonora Petito, Giulio Spinozzi, Sharon Shacham, Yosef Landesman, Concetta Quintarelli, Paolo Gresele, Franco Locatelli, Maria Paola Martelli, Brunangelo Falini, Lorenzo Brunetti
Journal: Blood Advances
Blood Adv (2022) 6 (22): 5938–5949.
https://doi.org/10.1182/bloodadvances.2022007563
Published: 2022
Includes: Supplemental data
Journal Articles

Blinatumomab in pediatric relapsed/refractory B-cell acute lymphoblastic leukemia: RIALTO expanded access study final analysis

Clinical Trials & Observations
Franco Locatelli, Gerhard Zugmaier, Noemi Mergen, Peter Bader, Sima Jeha, Paul-Gerhardt Schlegel, Jean-Pierre Bourquin, Rupert Handgretinger, Benoit Brethon, Claudia Rössig, William N. Kormany, Puneeth Viswagnachar, Christiane Chen-Santel
Journal: Blood Advances
Blood Adv (2022) 6 (3): 1004–1014.
https://doi.org/10.1182/bloodadvances.2021005579
Published: 2022
Includes: Supplemental data
Journal Articles

TCRαβ/CD19 depleted HSCT from an HLA-haploidentical relative to treat children with different nonmalignant disorders

Clinical Trials & Observations
Pietro Merli, Daria Pagliara, Federica Galaverna, Giuseppina Li Pira, Marco Andreani, Giovanna Leone, Donato Amodio, Rita Maria Pinto, Alice Bertaina, Valentina Bertaina, Angela Mastronuzzi, Luisa Strocchio, Emilia Boccieri, Daniela Pende, Michela Falco, Matteo Di Nardo, Francesca Del Bufalo, Mattia Algeri, Franco Locatelli
Journal: Blood Advances
Blood Adv (2022) 6 (1): 281–292.
https://doi.org/10.1182/bloodadvances.2021005628
Published: 2022
Includes: Supplemental data
Journal Articles

Response to upfront azacitidine in juvenile myelomonocytic leukemia in the AZA-JMML-001 trial

Clinical Trials & Observations
Charlotte M. Niemeyer, Christian Flotho, Daniel B. Lipka, Jan Starý, Claudia Rössig, André Baruchel, Thomas Klingebiel, Concetta Micalizzi, Gérard Michel, Karsten Nysom, Susana Rives, Markus Schmugge Liner, Marco Zecca, Maximilian Schönung, Irith Baumann, Peter Nöllke, Bouchra Benettaib, Noha Biserna, Jennifer Poon, Mathew Simcock, Meera Patturajan, Daniel Menezes, Allison Gaudy, Marry M. van den Heuvel-Eibrink, Franco Locatelli
Journal: Blood Advances
Blood Adv (2021) 5 (14): 2901–2908.
https://doi.org/10.1182/bloodadvances.2020004144
Published: 2021
Includes: Supplemental data
Journal Articles

HLA-haploidentical TCRαβ + /CD19 + -depleted stem cell transplantation in children and young adults with Fanconi anemia

Clinical Trials & Observations
Luisa Strocchio, Daria Pagliara, Mattia Algeri, Giuseppina Li Pira, Francesca Rossi, Valentina Bertaina, Giovanna Leone, Rita Maria Pinto, Marco Andreani, Emanuele Agolini, Katia Girardi, Stefania Gaspari, Lavinia Grapulin, Francesca del Bufalo, Antonio Novelli, Pietro Merli, Franco Locatelli
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1333–1339.
https://doi.org/10.1182/bloodadvances.2020003707
Published: 2021
Journal Articles

Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency type I and III

Clinical Trials & Observations
Shahrzad Bakhtiar, Emilia Salzmann-Manrique, Henric-Jan Blok, Dirk-Jan Eikema, Sheree Hazelaar, Mouhab Ayas, Amos Toren, Gal Goldstein, Despina Moshous, Franco Locatelli, Pietro Merli, Gerard Michel, Gülyüz Öztürk, Ansgar Schulz, Carsten Heilmann, Marianne Ifversen, Rob F. Wynn, Olga Aleinikova, Yves Bertrand, Abdelghani Tbakhi, Paul Veys, Musa Karakukcu, Alphan Kupesiz, Ardeshir Ghavamzadeh, Rupert Handgretinger, Emel Unal, Antonio Perez-Martinez, Muge Gokce, Fulvio Porta, Tekin Aksu, Gülsün Karasu, Isabel Badell, Per Ljungman, Elena Skorobogatova, Akif Yesilipek, Tsila Zuckerman, Robbert R. G. Bredius, Polina Stepensky, Bella Shadur, Mary Slatter, Andrew R. Gennery, Michael H. Albert, Peter Bader, Arjan Lankester
Journal: Blood Advances
Blood Adv (2021) 5 (1): 262–273.
https://doi.org/10.1182/bloodadvances.2020002185
Published: 2021
Includes: Supplemental data
Journal Articles

Possible roads to improve hemophagocytic lymphohistiocytosis outcome

Clinical Trials & Observations
Pietro Merli, Michael B. Jordan, Franco Locatelli
Journal: Blood Advances
Blood Adv (2020) 4 (24): 6127–6129.
https://doi.org/10.1182/bloodadvances.2020003263
Published: 2020
Journal Articles

Thioridazine requires calcium influx to induce MLL-AF6 –rearranged AML cell death

Claudia Tregnago, Ambra Da Ros, Elena Porcù, Maddalena Benetton, Manuela Simonato, Luca Simula, Giulia Borella, Katia Polato, Sonia Minuzzo, Giulia Borile, Paola Cogo, Silvia Campello, Alessandro Massi, Romeo Romagnoli, Barbara Buldini, Franco Locatelli, Martina Pigazzi
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4417–4429.
https://doi.org/10.1182/bloodadvances.2020002001
Published: 2020
Includes: Multimedia, Supplemental data