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Lorenzo Brunetti
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Journal Articles

Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1 -mutated AML

Clinical Trials & Observations
Giulia Pianigiani, Andrea Gagliardi, Federica Mezzasoma, Francesca Rocchio, Valentina Tini, Barbara Bigerna, Paolo Sportoletti, Simona Caruso, Andrea Marra, Sara Peruzzi, Eleonora Petito, Giulio Spinozzi, Sharon Shacham, Yosef Landesman, Concetta Quintarelli, Paolo Gresele, Franco Locatelli, Maria Paola Martelli, Brunangelo Falini, Lorenzo Brunetti
Journal: Blood Advances
Blood Adv (2022) 6 (22): 5938–5949.
https://doi.org/10.1182/bloodadvances.2022007563
Published: 2022
Includes: Supplemental data
Journal Articles

Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities

Jason H. Rogers, Rohit Gupta, Jaime M. Reyes, Michael C. Gundry, Geraldo Medrano, Anna Guzman, Rogelio Aguilar, Shannon E. Conneely, Tidie Song, Cade Johnson, Sean Barnes, Carlo D.D. Cristobal, Kristen Kurtz, Lorenzo Brunetti, Margaret A. Goodell, Rachel E. Rau
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3876–3890.
https://doi.org/10.1182/bloodadvances.2020002408
Published: 2021
Includes: Supplemental data
Journal Articles

Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells

Rafet Basar, May Daher, Nadima Uprety, Elif Gokdemir, Abdullah Alsuliman, Emily Ensley, Gonca Ozcan, Mayela Mendt, Mayra Hernandez Sanabria, Lucila Nassif Kerbauy, Ana Karen Nunez Cortes, Li Li, Pinaki P. Banerjee, Luis Muniz-Feliciano, Sunil Acharya, Natalie W. Fowlkes, Junjun Lu, Sufang Li, Stephan Mielke, Mecit Kaplan, Vandana Nandivada, Mustafa Bdaiwi, Alexander D. Kontoyiannis, Ye Li, Enli Liu, Sonny Ang, David Marin, Lorenzo Brunetti, Michael C. Gundry, Rolf Turk, Mollie S. Schubert, Garrett R. Rettig, Matthew S. McNeill, Gavin Kurgan, Mark A. Behlke, Richard Champlin, Elizabeth J. Shpall, Katayoun Rezvani
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3357–3367.
https://doi.org/10.1182/bloodadvances.2020001977
Published: 2020
Includes: Supplemental data