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Guy Sauvageau
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Journal Articles

UM171 enhances fitness and engraftment of gene-modified hematopoietic stem cells from patients with sickle cell disease

Boya Liu, Denise Klatt, Yu Zhou, John P. Manis, Guy Sauvageau, Danilo Pellin, Christian Brendel, David A. Williams
Journal: Blood Advances
Blood Adv (2024) 8 (22): 5885–5895.
https://doi.org/10.1182/bloodadvances.2024013932
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic deletion of JAM-C in preleukemic cells rewires leukemic stem cell gene expression program in AML

Julien M. P. Grenier, Céline Testut, Matthieu Bal, Florence Bardin, Maria De Grandis, Véronique Gelsi-Boyer, Julien Vernerey, Marjorie Delahaye, Samuel Granjeaud, Christophe Zemmour, Jean-François Spinella, Triantafyllos Chavakis, Stéphane J. C. Mancini, Jean-Marie Boher, Josée Hébert, Guy Sauvageau, Norbert Vey, Jürg Schwaller, Marie-Anne Hospital, Cyril Fauriat, Michel Aurrand-Lions
Journal: Blood Advances
Blood Adv (2024) 8 (17): 4662–4678.
https://doi.org/10.1182/bloodadvances.2023011747
Published: 2024
Includes: Supplemental data
Journal Articles

CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-X L inhibition by navitoclax and DT2216

Verena Gress, Mathieu Roussy, Luc Boulianne, Mélanie Bilodeau, Sophie Cardin, Nehme El-Hachem, Véronique Lisi, Banafsheh Khakipoor, Alexandre Rouette, Azer Farah, Louis Théret, Léo Aubert, Furat Fatima, Éric Audemard, Pierre Thibault, Éric Bonneil, Jalila Chagraoui, Louise Laramée, Patrick Gendron, Loubna Jouan, Safa Jammali, Bastien Paré, Shawn M. Simpson, Thai Hoa Tran, Michel Duval, Pierre Teira, Henrique Bittencourt, Raoul Santiago, Frédéric Barabé, Guy Sauvageau, Martin A. Smith, Josée Hébert, Philippe P. Roux, Tanja A. Gruber, Vincent-Philippe Lavallée, Brian T. Wilhelm, Sonia Cellot
Journal: Blood Advances
Blood Adv (2023) 8 (1): 112–129.
https://doi.org/10.1182/bloodadvances.2022008899
Published: 2023
Includes: Supplemental data
Journal Articles

GPRC5C drives branched-chain amino acid metabolism in leukemogenesis

Yu Wei Zhang, Talia Velasco-Hernandez, Julian Mess, Maria-Eleni Lalioti, Mari Carmen Romero-Mulero, Nadine Obier, Nikolaos Karantzelis, Jasmin Rettkowski, Katharina Schönberger, Noémie Karabacz, Karin Jäcklein, Tatsuya Morishima, Juan Luis Trincado, Paola Romecin, Alba Martinez, Hitoshi Takizawa, Khalid Shoumariyeh, Simon Renders, Robert Zeiser, Heike L. Pahl, François Béliveau, Josée Hébert, Bernhard Lehnertz, Guy Sauvageau, Pablo Menendez, Nina Cabezas-Wallscheid
Journal: Blood Advances
Blood Adv (2023) 7 (24): 7525–7538.
https://doi.org/10.1182/bloodadvances.2023010460
Published: 2023
Includes: Supplemental data
Journal Articles

Improved outcomes of UM171–expanded cord blood transplantation compared with other graft sources: real-world evidence

Clinical Trials & Observations
Sandra Cohen, Nadia Bambace, Imran Ahmad, Jean Roy, Xiaoying Tang, Mei-Jie Zhang, Linda Burns, Frédéric Barabé, Léa Bernard, Jean-Sébastien Delisle, Thomas Kiss, Silvy Lachance, Denis-Claude Roy, Olivier Veilleux, Guy Sauvageau
Journal: Blood Advances
Blood Adv (2023) 7 (19): 5717–5726.
https://doi.org/10.1182/bloodadvances.2023010599
Published: 2023
Includes: Supplemental data
Journal Articles

Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia

Véronique Lisi, Ève Blanchard, Michael Vladovsky, Éric Audemard, Albert Ferghaly, Sébastien Lemieux, Josée Hébert, Guy Sauvageau, Vincent-Philippe Lavallée
Journal: Blood Advances
Blood Adv (2022) 6 (17): 5160–5164.
https://doi.org/10.1182/bloodadvances.2022007300
Published: 2022
Includes: Supplemental data
Journal Articles

HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition

Céline Moison, Jean-François Spinella, Jalila Chagraoui, Vincent-Philippe Lavallée, Bernhard Lehnertz, Clarisse Thiollier, Isabel Boivin, Nadine Mayotte, Tara MacRae, Anne Marinier, Josée Hébert, Guy Sauvageau
Journal: Blood Advances
Blood Adv (2022) 6 (16): 4793–4806.
https://doi.org/10.1182/bloodadvances.2021005828
Published: 2022
Includes: Supplemental data
Journal Articles

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells

Unain Ansari, Elisa Tomellini, Jalila Chagraoui, Bernhard Lehnertz, Nadine Mayotte, Marie-Eve Bordeleau, Philippe P. Roux, Guy Sauvageau
Journal: Blood Advances
Blood Adv (2022) 6 (12): 3626–3631.
https://doi.org/10.1182/bloodadvances.2021006835
Published: 2022
Includes: Supplemental data
Journal Articles

Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia

Jana Krosl, Marie-Eve Bordeleau, Céline Moison, Tara MacRae, Isabel Boivin, Nadine Mayotte, Deanne Gracias, Irène Baccelli, Vincent-Philippe Lavallée, Richard Bisaillon, Bernhard Lehnertz, Rodrigo Mendoza-Sanchez, Réjean Ruel, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Nandita Noronha, Caroline Pabst, Mike Tyers, Patrick Gendron, Sébastien Lemieux, Frédéric Barabé, Anne Marinier, Josée Hébert, Guy Sauvageau
Journal: Blood Advances
Blood Adv (2022) 6 (2): 509–514.
https://doi.org/10.1182/bloodadvances.2021006047
Published: 2022
Includes: Supplemental data
Journal Articles

Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition

Céline Moison, Vincent-Philippe Lavallée, Clarisse Thiollier, Bernhard Lehnertz, Isabel Boivin, Nadine Mayotte, Yves Gareau, Mélanie Fréchette, Valérie Blouin-Chagnon, Sophie Corneau, Sylvie Lavallée, Sébastien Lemieux, Anne Marinier, Josée Hébert, Guy Sauvageau
Journal: Blood Advances
Blood Adv (2019) 3 (4): 552–563.
https://doi.org/10.1182/bloodadvances.2018028480
Published: 2019
Includes: Supplemental data