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Volume 95, Issue 10

May 15 2000

In this Issue

PLENARY PAPERS
ERRATA
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
CORRESPONDENCE

PLENARY PAPERS

Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-β1 is a cell cycle–independent effect and influences their hematopoietic potential

Luca Pierelli,Maria Marone,Giuseppina Bonanno,Simona Mozzetti,Sergio Rutella,Roberta Morosetti,Carlo Rumi,Salvatore Mancuso,Giuseppe Leone,Giovanni Scambia

View Articletitled, Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-β1 is a cell cycle–independent effect and influences their hematopoietic potential

Sustaining the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)–producing tumor vaccines

Ivan Borrello,Eduardo M. Sotomayor,Frédérique-Marie Rattis,Sara K. Cooke,Lingping Gu,Hyam I. Levitsky

View Articletitled, Sustaining the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)–producing tumor vaccines

Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease

Volkhard Seitz,Michael Hummel,Theresa Marafioti,Ioannis Anagnostopoulos,Chalid Assaf,Harald Stein

View Articletitled, Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease

Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF

Fulu Liu,Jennifer Poursine-Laurent,Daniel C. Link

View Articletitled, Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF

ERRATA

Erratum in Panzer-Grümayer et al. Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia. Blood. 2000;95:790-794.

View Articletitled, Erratum in Panzer-Grümayer et al. Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia. Blood. 2000;95:790-794.

REVIEW ARTICLES

Chemokine receptors and their role in inflammation and infectious diseases

Craig Murdoch,Adam Finn

View Articletitled, Chemokine receptors and their role in inflammation and infectious diseases

CHEMOKINES

Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells

Stefan Hippenstiel,Saskia Soeth,Birgit Kellas,Oliver Fuhrmann,Joachim Seybold,Matthias Krüll,Christoph v. Eichel-Streiber,Matthias Goebeler,Stephan Ludwig,Norbert Suttorp

View Articletitled, Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin lymphoma
Clinical Trials & Observations

John D. Hainsworth,Howard A. Burris, III,Lisa H. Morrissey,Sharlene Litchy,Daniel C. Scullin, Jr,James D. Bearden, III,Paul Richards,F. Anthony Greco

View Articletitled, Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin lymphoma

Bone marrow transplantation versus periodic prophylactic blood transfusion in sickle cell patients at high risk of ischemic stroke: a decision analysis
Clinical Trials & Observations

Paul J. Nietert,Miguel R. Abboud,Marc D. Silverstein,Sherron M. Jackson

View Articletitled, Bone marrow transplantation versus periodic prophylactic blood transfusion in sickle cell patients at high risk of ischemic stroke: a decision analysis

Hepatitis C infection among survivors of childhood cancer
Clinical Trials & Observations

Donald K. Strickland,Caroline A. Riely,Christian C. Patrick,Dana Jones-Wallace,James M. Boyett,Bradford Waters,Jaquelyn Fitch Fleckenstein,Patrick J. Dean,Rene Davila,Tony E. Caver,Melissa M. Hudson

View Articletitled, Hepatitis C infection among survivors of childhood cancer

GENE THERAPY

Stable and functional lymphoid reconstitution of common cytokine receptor γ chain deficient mice by retroviral-mediated gene transfer

Claire Soudais,Tsujino Shiho,Lama I. Sharara,Delphine Guy-Grand,Tadatsugu Taniguchi,Alain Fischer,James P. Di Santo

View Articletitled, Stable and functional lymphoid reconstitution of common cytokine receptor γ chain deficient mice by retroviral-mediated gene transfer

Limiting numbers of G156A O⁶-methylguanine–DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection

Brian M. Davis,Omer N. Koç,Stanton L. Gerson

View Articletitled, Limiting numbers of G156A O6-methylguanine–DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection

Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice

Jordi Barquinero,José Carlos Segovia,Manuel Ramı́rez,Ana Limón,Guillermo Güenechea,Teresa Puig,Javier Briones,Juan Garcı́a,Juan Antonio Bueren

View Articletitled, Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice

HEMATOPOIESIS

The role of platelet α-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cells

Ranita Sungaran,Orin T. Chisholm,Boban Markovic,Levon M. Khachigian,Yoshihiro Tanaka,Beng H. Chong

View Articletitled, The role of platelet α-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cells

β2 Microglobulin-deficient (B2m^null) NOD/SCID mice are excellent recipients for studying human stem cell function

Orit Kollet,Amnon Peled,Tamara Byk,Herzl Ben-Hur,Dale Greiner,Leonard Shultz,Tsvee Lapidot

View Articletitled, β2 Microglobulin-deficient (B2mnull) NOD/SCID mice are excellent recipients for studying human stem cell function

In vitro differentiation of endothelial cells from AC133-positive progenitor cells

Ursula M. Gehling,Süleyman Ergün,Udo Schumacher,Christoph Wagener,Klaus Pantel,Marcus Otte,Gunter Schuch,Philippe Schafhausen,Thorsten Mende,Nerbil Kilic,Katrin Kluge,Birgit Schäfer,Dieter K. Hossfeld,Walter Fiedler

View Articletitled, In vitro differentiation of endothelial cells from AC133-positive progenitor cells

Functionally defined CD164 epitopes are expressed on CD34⁺ cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

Suzanne M. Watt,Lisa H. Butler,Manuela Tavian,Hans-Jörg Bühring,Irene Rappold,Paul J. Simmons,Andrew C. W. Zannettino,David Buck,Anja Fuchs,Regis Doyonnas,James Yi-Hsin Chan,Jean-Pierre Levesque,Bruno Peault,Ioannis Roxanis

View Articletitled, Functionally defined CD164 epitopes are expressed on CD34+ cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins

J. Megan M. Patterson,Michael H. Johnson,Drazen B. Zimonjic,Timothy A. Graubert

View Articletitled, Characterization of Ly-6M, a novel member of the Ly-6 family of hematopoietic proteins

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells: Presented at the 40th annual meeting of the American Society of Hematology, Miami, FL, December 1998.

Jasmine Zain,Yao-Qi Huang,XueSheng Feng,Mary Lynn Nierodzik,Jian-Jun Li,Simon Karpatkin

View Articletitled, Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells: Presented at the 40th annual meeting of the American Society of Hematology, Miami, FL, December 1998.

Conformational changes in the D′ domain of von Willebrand factor induced by CYS 25 and CYS 95 mutations lead to factor VIII binding defect and multimeric impairment

Sylvie Jorieux,Edith Fressinaud,Jenny Goudemand,Christine Gaucher,Dominique Meyer,Claudine Mazurier,the INSERM Network on Molecular Abnormalities in von Willebrand Disease

View Articletitled, Conformational changes in the D′ domain of von Willebrand factor induced by CYS 25 and CYS 95 mutations lead to factor VIII binding defect and multimeric impairment

Interleukin-13 induces PSGL-1/P–selectin–dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow

Gerrit Woltmann,Claire A. McNulty,Grant Dewson,Fiona A. Symon,Andrew J. Wardlaw

View Articletitled, Interleukin-13 induces PSGL-1/P–selectin–dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow

IMMUNOBIOLOGY

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness

Hans J. P. M. Koenen,Irma Joosten

View Articletitled, Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness

Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10

Delphine Rea,Cees van Kooten,Krista E. van Meijgaarden,Tom H. M. Ottenhoff,Cornelis J. M. Melief,Rienk Offringa

View Articletitled, Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10

Thrombocyte HLA molecules retain nonrenewable endogenous peptides of megakaryocyte lineage and do not stimulate direct allocytotoxicity in vitro

Cécile Gouttefangeas,Marianne Diehl,Wieland Keilholz,Rainer Frank Hörnlein,Stefan Stevanović,Hans-Georg Rammensee

View Articletitled, Thrombocyte HLA molecules retain nonrenewable endogenous peptides of megakaryocyte lineage and do not stimulate direct allocytotoxicity in vitro

Deficiency of the Fas apoptosis pathway without Fas gene mutations is a familial trait predisposing to development of autoimmune diseases and cancer

Ugo Ramenghi,Sara Bonissoni,Giuseppe Migliaretti,Simona DeFranco,Flavia Bottarel,Caterina Gambaruto,Daniela DiFranco,Roberta Priori,Fabrizio Conti,Irma Dianzani,Guido Valesini,Franco Merletti,Umberto Dianzani

View Articletitled, Deficiency of the Fas apoptosis pathway without Fas gene mutations is a familial trait predisposing to development of autoimmune diseases and cancer

Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4

Kathy S. Wang,David A. Frank,Jerome Ritz

View Articletitled, Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4

Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus–associated lipodystrophy syndrome

Eric Ledru,Névéna Christeff,Olivier Patey,Pierre de Truchis,Jean-Claude Melchior,Marie-Lise Gougeon

View Articletitled, Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus–associated lipodystrophy syndrome

RasGRP links T-cell receptor signaling to Ras

Julius O. Ebinu,Stacey L. Stang,Christine Teixeira,Drell A. Bottorff,Jonathan Hooton,Peter M. Blumberg,Michele Barry,R. Chris Bleakley,Hanne L. Ostergaard,James C. Stone

View Articletitled, RasGRP links T-cell receptor signaling to Ras

NEOPLASIA

Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like)

Christian Touriol,Catherine Greenland,Laurence Lamant,Karen Pulford,Frédéric Bernard,Thérèse Rousset,David Y. Mason,Georges Delsol

View Articletitled, Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like)

Hypermethylation of E-cadherin in leukemia

John R. Melki,Paul C. Vincent,Ross D. Brown,Susan J. Clark

View Articletitled, Hypermethylation of E-cadherin in leukemia

Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

Hiroshi Sakamoto,Tetsuo Mashima,Atsuo Kizaki,Shingo Dan,Yuichi Hashimoto,Mikihiko Naito,Takashi Tsuruo

View Articletitled, Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

Chronic neutropenia mediated by Fas ligand

Jin Hong Liu,Sheng Wei,Thierry Lamy,P. K. Epling-Burnette,Gordon Starkebaum,Julie Y. Djeu,Thomas P. Loughran, Jr

View Articletitled, Chronic neutropenia mediated by Fas ligand

PHAGOCYTES

The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators

Michael Centola,Geryl Wood,David M. Frucht,Jerome Galon,Martin Aringer,Christopher Farrell,Douglas W. Kingma,Mitchell E. Horwitz,Elizabeth Mansfield,Steven M. Holland,John J. O'Shea,Helene F. Rosenberg,Harry L. Malech,Daniel L. Kastner

View Articletitled, The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators

RED CELLS

Perfusion with sickle erythrocytes up-regulates ICAM-1 andVCAM-1 gene expression in cultured human endothelial cells

Yan-Ting Shiu,Mark M. Udden,Larry V. McIntire

View Articletitled, Perfusion with sickle erythrocytes up-regulates ICAM-1 andVCAM-1 gene expression in cultured human endothelial cells

Locus control region activity by 5′HS3 requires a functional interaction with β-globin gene regulatory elements: expression of novel β/γ-globin hybrid transgenes

Joel E. Rubin,Peter Pasceri,Xiumei Wu,Philippe Leboulch,James Ellis

View Articletitled, Locus control region activity by 5′HS3 requires a functional interaction with β-globin gene regulatory elements: expression of novel β/γ-globin hybrid transgenes

A novel mutation in the NADH-cytochrome b5 reductase gene of a Chinese patient with recessive congenital methemoglobinemia

Yao Wang,Yu-Shui Wu,Pei-Zhen Zheng,Wen-Xi Yang,Guo-An Fang,Yu-Chai Tang,Fei Xie,Feng-Hua Lan,Zhong-Yong Zhu

View Articletitled, A novel mutation in the NADH-cytochrome b5 reductase gene of a Chinese patient with recessive congenital methemoglobinemia

TRANSPLANTATION

Herpesvirus saimiri–transformed macaque T cells are tolerated and do not cause lymphoma after autologous reinfusion

Andrea Knappe,Gisela Feldmann,Ulf Dittmer,Edgar Meinl,Thomas Nisslein,Sabine Wittmann,Kerstin Mätz-Rensing,Thomas Kirchner,Walter Bodemer,Helmut Fickenscher

View Articletitled, Herpesvirus saimiri–transformed macaque T cells are tolerated and do not cause lymphoma after autologous reinfusion

Adoptive immunotherapy in canine mixed chimeras after nonmyeloablative hematopoietic cell transplantation

George E. Georges,Rainer Storb,Jennifer D. Thompson,Cong Yu,Ted Gooley,Benedetto Bruno,Richard A. Nash

View Articletitled, Adoptive immunotherapy in canine mixed chimeras after nonmyeloablative hematopoietic cell transplantation

CORRESPONDENCE

Gentle microinjection for myeloid cells using SLAM

Iraj Laffafian,Maurice B. Hallett

View Articletitled, Gentle microinjection for myeloid cells using SLAM

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Cardiac complete response in AL amyloidosis has similar survival to matched general population

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Heme induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice

Interleukin-1 mediated hyperinflammation in XIAP-deficiency is associated with defective autophagy.

NOVEL THERAPEUTIC APPROACHES IN THALASSEMIAS, SICKLE CELL DISEASE AND OTHER RED CELL DISORDERS

Issue Archive

Table of Contents

PLENARY PAPERS

ERRATA

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin lymphoma Clinical Trials & Observations

Bone marrow transplantation versus periodic prophylactic blood transfusion in sickle cell patients at high risk of ischemic stroke: a decision analysis Clinical Trials & Observations

Hepatitis C infection among survivors of childhood cancer Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

NEOPLASIA

PHAGOCYTES

RED CELLS

TRANSPLANTATION

CORRESPONDENCE

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ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin lymphoma
Clinical Trials & Observations

Bone marrow transplantation versus periodic prophylactic blood transfusion in sickle cell patients at high risk of ischemic stroke: a decision analysis
Clinical Trials & Observations

Hepatitis C infection among survivors of childhood cancer
Clinical Trials & Observations