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Issue Archive

Volume 132, Issue 6
August 9 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

Hematopoiesis and Stem Cells
CASIN the joint: immune aging at the stem cell level
Graham P. Pawelec
View Articletitled, CASIN the joint: immune aging at the stem cell level
Lymphoid Neoplasia
Detailing the genomic landscape of myeloma
P. Leif Bergsagel,W. Michael Kuehl
View Articletitled, Detailing the genomic landscape of myeloma
PLATELETS AND THROMBOPOIESIS
TPO-logy accepted
Karin M. Hoffmeister
View Articletitled, TPO-logy accepted
CLINICAL TRIALS AND OBSERVATIONS
Endosome trafficking: blood and more
Clinical Trials & Observations
Gary M. Kupfer
View Articletitled, Endosome trafficking: blood and more

BLOOD SPOTLIGHT

Hematopoiesis and the bacterial microbiome
Hannah Yan,Megan T. Baldridge,Katherine Y. King
View Articletitled, Hematopoiesis and the bacterial microbiome

HEMATOPOIESIS AND STEM CELLS

Aged murine hematopoietic stem cells drive aging-associated immune remodeling
Hanna Leins,Medhanie Mulaw,Karina Eiwen,Vadim Sakk,Ying Liang,Michael Denkinger,Hartmut Geiger,Reinhold Schirmbeck
View Articletitled, Aged murine hematopoietic stem cells drive aging-associated immune remodeling
Supplemental data

LYMPHOID NEOPLASIA

CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma
Ajinkya Patil,Mark Manzano,Eva Gottwein
View Articletitled, CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma
Supplemental data
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Brian A. Walker,Konstantinos Mavrommatis,Christopher P. Wardell,T. Cody Ashby,Michael Bauer,Faith E. Davies,Adam Rosenthal,Hongwei Wang,Pingping Qu,Antje Hoering,Mehmet Samur,Fadi Towfic,Maria Ortiz,Erin Flynt,Zhinuan Yu,Zhihong Yang,Dan Rozelle,John Obenauer,Matthew Trotter,Daniel Auclair,Jonathan Keats,Niccolo Bolli,Mariateresa Fulciniti,Raphael Szalat,Philippe Moreau,Brian Durie,A. Keith Stewart,Hartmut Goldschmidt,Marc S. Raab,Hermann Einsele,Pieter Sonneveld,Jesus San Miguel,Sagar Lonial,Graham H. Jackson,Kenneth C. Anderson,Herve Avet-Loiseau,Nikhil Munshi,Anjan Thakurta,Gareth J. Morgan
View Articletitled, Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Supplemental data

MYELOID NEOPLASIA

Phase 2b study of 2 dosing regimens of quizartinib monotherapy in FLT3-ITD–mutated, relapsed or refractory AML
Clinical Trials & Observations
Jorge E. Cortes,Martin S. Tallman,Gary J. Schiller,Denise Trone,Guy Gammon,Stuart L. Goldberg,Alexander E. Perl,Jean-Pierre Marie,Giovanni Martinelli,Hagop M. Kantarjian,Mark J. Levis
View Articletitled, Phase 2b study of 2 dosing regimens of quizartinib monotherapy in <em>FLT3</em>-ITD–mutated, relapsed or refractory AML
Supplemental data
Srsf2P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells
Monique F. Smeets,Shuh Ying Tan,Jane Jialu Xu,Govardhan Anande,Ashwin Unnikrishnan,Alistair M. Chalk,Scott R. Taylor,John E. Pimanda,Meaghan Wall,Louise E. Purton,Carl R. Walkley
View Articletitled, <em>Srsf2</em><em><sup>P95H</sup></em> initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells
Supplemental data

PLATELETS AND THROMBOPOIESIS

GPIbα is required for platelet-mediated hepatic thrombopoietin generation
Miao Xu,June Li,Miguel Antonio Dias Neves,Guangheng Zhu,Naadiya Carrim,Ruoying Yu,Sahil Gupta,John Marshall,Ori Rotstein,Jun Peng,Ming Hou,Shinji Kunishima,Jerry Ware,Donald R. Branch,Alan H. Lazarus,Zaverio M. Ruggeri,John Freedman,Heyu Ni
View Articletitled, GPIbα is required for platelet-mediated hepatic thrombopoietin generation
Supplemental data
ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia
Markus Spindler,Judith M. M. van Eeuwijk,Yvonne Schurr,Paquita Nurden,Bernhard Nieswandt,David Stegner,Annegret Reinhold,Markus Bender
View Articletitled, ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia
Supplemental data

THROMBOSIS AND HEMOSTASIS

Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition
Sangwook Wu,Xuejie Chen,Da-Yun Jin,Darrel W. Stafford,Lee G. Pedersen,Jian-Ke Tie
View Articletitled, Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition
Supplemental data

LETTERS TO BLOOD

Syndromic congenital myelofibrosis associated with a loss-of-function variant in RBSN
Clinical Trials & Observations
Pilar L. Magoulas,Oleg A. Shchelochkov,Matthew N. Bainbridge,Shay Ben-Shachar,Svetlana Yatsenko,Lorraine Potocki,Richard A. Lewis,Charles Searby,Andrea N. Marcogliese,M. Tarek Elghetany,Gladys Zapata,Paula P. Hernández,Manasi Gadkari,Derek Einhaus,Donna M. Muzny,Richard A. Gibbs,Alison A. Bertuch,Daryl A. Scott,Silvia Corvera,Luis M. Franco
View Articletitled, Syndromic congenital myelofibrosis associated with a loss-of-function variant in <em>RBSN</em>
Supplemental data
Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques
Anandani Nellan,Cynthia M. Lester McCully,Rafael Cruz Garcia,Nalini Jayaprakash,Brigitte C. Widemann,Daniel W. Lee,Katherine E. Warren
View Articletitled, Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques
Rituximab monotherapy in splenic marginal zone lymphoma: prolonged responses and potential benefit from maintenance
Christina Kalpadakis,Gerassimos A. Pangalis,Sotirios Sachanas,Pantelis Tsirkinidis,Flora N. Kontopidou,Maria Moschogiannis,Xanthi Yiakoumis,Efstathios Koulieris,Maria N. Dimopoulou,Stella I. Kokkoris,Marie-Christine Kyrtsonis,Marina P. Siakantaris,Gerassimos Tsourouflis,Penelope Korkolopoulou,Dimitra Rontogianni,Panagiotis Tsaftaridis,Eleni Plata,Helen A. Papadaki,Panagiotis Panagiotidis,Maria K. Angelopoulou,Theodoros P. Vassilakopoulos
View Articletitled, Rituximab monotherapy in splenic marginal zone lymphoma: prolonged responses and potential benefit from maintenance
A universal solution for eliminating false positives in myeloma due to therapeutic monoclonal antibody interference
John R. Mills,Mindy C. Kohlhagen,Maria A. V. Willrich,Taxiarchis Kourelis,Angela Dispenzieri,David L. Murray
View Articletitled, A universal solution for eliminating false positives in myeloma due to therapeutic monoclonal antibody interference

BLOOD WORK

Rasburicase-induced hemolytic anemia in previously undiagnosed G6PD deficiency
Donna Ferguson,Alexandra E. Kovach
View Articletitled, Rasburicase-induced hemolytic anemia in previously undiagnosed G6PD deficiency
All Issues

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