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Journal Articles

Phase 2 March Study: ATG-010 Plus Low Dose Dexamethasone in Chinese Relapsed/Refractory Multiple Myeloma (RRMM) Patients Previously Treated with an Immunomodulatory Agent (IMiD) and a Proteasome Inhibitor (PI)

Lugui Qiu, Weijun Fu, Zhongjun Xia, Zhengzheng Fu, Wenming Chen, Chunkang Chang, Baijun Fang, Gang An, Yongqiang Wei, Zhen Cai, Sujun Gao, Jianyu Weng, Lijuan Chen, Hongmei Jing, Li Fei, Zhuogang Liu, Xiequn Chen, Jing Liu, Yang Yu, Aihua Wang, Yijun Yang, Zhinuan Yu, Kevin Lynch
Journal: Blood
Blood (2021) 138 (Supplement 1): 4770.
https://doi.org/10.1182/blood-2021-145282
Published: 2021
Journal Articles

ATG-010 Plus Low-Dose Dexamethasone (Sd) in Chinese Relapsed/Refractory Multiple Myeloma (RRMM) Patients Previously Received Chimeric Antigen Receptor T-Cell (CAR-T)

Weijun Fu, Lugui Qiu, Zhongjun Xia, Zhengzheng Fu, Wenming Chen, Chunkang Chang, Baijun Fang, Gang An, Yongqiang Wei, Zhen Cai, Sujun Gao, Jianyu Weng, Lijuan Chen, Hongmei Jing, Li Fei, Zhuogang Liu, Xiequn Chen, Jing Liu, Yang Yu, Aihua Wang, Zhinuan Yu, Yijun Yang, Kevin Lynch
Journal: Blood
Blood (2021) 138 (Supplement 1): 4778.
https://doi.org/10.1182/blood-2021-146784
Published: 2021
Journal Articles

High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma

Brief Report
Anjan Thakurta, Maria Ortiz, Pedro Blecua, Fadi Towfic, Jill Corre, Natalya V. Serbina, Erin Flynt, Zhinuan Yu, Zhihong Yang, Antonio Palumbo, Meletios A. Dimopoulos, Norma C. Gutierrez, Hartmut Goldschmidt, Pieter Sonneveld, Herve Avet-Loiseau
Journal: Blood
Blood (2019) 133 (11): 1217–1221.
https://doi.org/10.1182/blood-2018-10-880831
Published: 2019
Includes: Supplemental data
Journal Articles

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

Brian A. Walker, Konstantinos Mavrommatis, Christopher P. Wardell, T. Cody Ashby, Michael Bauer, Faith E. Davies, Adam Rosenthal, Hongwei Wang, Pingping Qu, Antje Hoering, Mehmet Samur, Fadi Towfic, Maria Ortiz, Erin Flynt, Zhinuan Yu, Zhihong Yang, Dan Rozelle, John Obenauer, Matthew Trotter, Daniel Auclair, Jonathan Keats, Niccolo Bolli, Mariateresa Fulciniti, Raphael Szalat, Philippe Moreau, Brian Durie, A. Keith Stewart, Hartmut Goldschmidt, Marc S. Raab, Hermann Einsele, Pieter Sonneveld, Jesus San Miguel, Sagar Lonial, Graham H. Jackson, Kenneth C. Anderson, Herve Avet-Loiseau, Nikhil Munshi, Anjan Thakurta, Gareth J. Morgan
Journal: Blood
Blood (2018) 132 (6): 587–597.
https://doi.org/10.1182/blood-2018-03-840132
Published: 2018
Includes: Supplemental data
Journal Articles

Peripheral Neuropathy (PN) with Immunomodulatory Drugs in Patients with Multiple Myeloma (MM)

Melinda Mezo, Carmen Castaneda, Lilia Weiss, Neil Minton, Damien Hirsch, Christine Renz, Uma Arunagiri, MD, Benton Brown, Dominique Gambini, MD, Michael Peng, Zhinuan Yu, PhD, Xin Yu, John Freeman
Journal: Blood
Blood (2016) 128 (22): 5677.
https://doi.org/10.1182/blood.V128.22.5677.5677
Published: 2016
Journal Articles

The Multiple Myeloma Genome Project: Development of a Molecular Segmentation Strategy for the Clinical Classification of Multiple Myeloma

Brian A Walker, PhD, Mehmet K. Samur, PhD, Konstantinos Mavrommatis, Cody Ashby, PhD, Christopher P Wardell, PhD, Maria Ortiz, PhD, Fadi Towfic, Caleb K. Stein, MS, Michael A Bauer, PhD, Michael Amatangelo, PhD, Giovanni Parmigiani, PhD, Zhinuan Yu, PhD, Matthew Trotter, Herve Avet-Loiseau, MD PhD, Graham H Jackson, MD PhD, Kenneth C. Anderson, Anjan Thakurta, PhD, Nikhil C. Munshi, MD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 196.
https://doi.org/10.1182/blood.V128.22.196.196
Published: 2016
Journal Articles

Incidence of Varicella Zoster Virus (VZV) and Herpes Simplex Virus (HSV) Infections and Use of Prophylaxis in Lenalidomide-Treated Multiple Myeloma (MM) Patients (pts): An Analysis of MM Trials

Dianna Gary, BSN, Lilia Weiss, MD, Zhinuan Yu, PhD, Qiang Xu, PhD, Neil Minton, MD, David Gillen, MD, Axel Glasmacher, MD, John Freeman, MSc, BSc, JD
Journal: Blood
Blood (2014) 124 (21): 3451.
https://doi.org/10.1182/blood.V124.21.3451.3451
Published: 2014
Journal Articles

Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study

Clinical Trials & Observations
Paul G. Richardson, David S. Siegel, Ravi Vij, Craig C. Hofmeister, Rachid Baz, Sundar Jagannath, Christine Chen, Sagar Lonial, Andrzej Jakubowiak, Nizar Bahlis, Kevin Song, Andrew Belch, Noopur Raje, Chaim Shustik, Suzanne Lentzsch, Martha Lacy, Joseph Mikhael, Jeffrey Matous, David Vesole, Min Chen, Mohamed H. Zaki, Christian Jacques, Zhinuan Yu, Kenneth C. Anderson
Journal: Blood
Blood (2014) 123 (12): 1826–1832.
https://doi.org/10.1182/blood-2013-11-538835
Published: 2014
Journal Articles

PFS2 In Elderly Patients With Newly Diagnosed Multiple Myeloma (NDMM): Results From The MM-015 Study

Meletios A. Dimopoulos, MD, Maria Teresa Petrucci, MD, Robin Foà, MD, John V. Catalano, MD, Martin Kropff, MD, Zhinuan Yu, PhD, Lara Grote, Christian J. Jacques, MD, Antonio Palumbo, MD
Journal: Blood
Blood (2013) 122 (21): 405.
https://doi.org/10.1182/blood.V122.21.405.405
Published: 2013
Journal Articles

Analysis of Second-Line Lenalidomide Following Initial Relapse in the MM-015 Trial

Meletios A Dimopoulos, MD, Maria Teresa Petrucci, MD, Robin Foa, MD, John V. Catalano, MD, Martin Kropff, MD, Zhinuan Yu, PhD, Lindsay Herbein, BS, Christian J. Jacques, MD, Antonio Palumbo, MD
Journal: Blood
Blood (2012) 120 (21): 944.
https://doi.org/10.1182/blood.V120.21.944.944
Published: 2012
Journal Articles

A review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomide

Brief Report
Meletios A. Dimopoulos, Paul G. Richardson, Nancy Brandenburg, Zhinuan Yu, Donna M. Weber, Ruben Niesvizky, Gareth J. Morgan
Journal: Blood
Blood (2012) 119 (12): 2764–2767.
https://doi.org/10.1182/blood-2011-08-373514
Published: 2012
Journal Articles

A Phase 3 Study Evaluating the Efficacy and Safety of Lenalidomide (Len) Combined with Melphalan and Prednisone Followed by Continuous Lenalidomide Maintenance (MPR-R) in Patients (Pts) ≥ 65 Years (Yrs) with Newly Diagnosed Multiple Myeloma (NDMM): Updated Results for Pts Aged 65–75 Yrs Enrolled in MM-015

Antonio Palumbo, MD, Zdenek Adam, Martin Kropff, MD, Robin Foà, John Catalano, MBBS FRACP FRCPA, Heinz Gisslinger, MD, Wieslaw Wiktor-Jedrzejczak, MD, PhD, Michel Delforge, MD, PhD, Katja Weisel, MD, Nicola Cascavilla, MD, Jan Van Droogenbroeck, Genadi Iosava, MD, Michele Cavo, MD, Joan Blade, Meral Beksac, MD, Ivan Spicka, MD, PhD, Torben Plesner, MD, Zhinuan Yu, Lindsey Herbein, Jay Mei, MD, PhD, Christian J. Jacques, Meletios Athanasios Dimopoulos, MD
Journal: Blood
Blood (2011) 118 (21): 475.
https://doi.org/10.1182/blood.V118.21.475.475
Published: 2011
Journal Articles

Peripheral Neuropathy In Multiple Myeloma Patients Treated with Lenalidomide

Carmen Castaneda, Lilia Weiss, Neil A. Minton, MD, MRCP, Alex Kim, John Freeman, Zhinuan Yu, Robert Knight, MD
Journal: Blood
Blood (2010) 116 (21): 5024.
https://doi.org/10.1182/blood.V116.21.5024.5024
Published: 2010
Journal Articles

A Phase 3 Study Evaluating the Efficacy and Safety of Lenalidomide Combined with Melphalan and Prednisone In Patients ≥ 65 Years with Newly Diagnosed Multiple Myeloma (NDMM): Continuous Use of Lenalidomide Vs Fixed-Duration Regimens

Antonio Palumbo, MD, Michel Delforge, MD, PhD, John Catalano, MBBS, FRACP, FRCPA, Roman Hajek, MD, PhD, Martin Kropff, MD, Maria Teresa Petrucci, Zhinuan Yu, Lindsey Herbein, Jay M. Mei, MD, PhD, Christian J. Jacques, MD, Meletios A. Dimopoulos
Journal: Blood
Blood (2010) 116 (21): 622.
https://doi.org/10.1182/blood.V116.21.622.622
Published: 2010
Journal Articles

A Phase III Study to Determine the Efficacy and Safety of Lenalidomide in Combination with Melphalan and Prednisone (MPR) in Elderly Patients with Newly Diagnosed Multiple Myeloma.

Antonio Palumbo, Meletios A. Dimopoulos, Michel Delforge, Martin Kropff, Robin Foa, Zhinuan Yu, Lindsay Herbein, Jay Mei, Christian Jacques, John Catalano
Journal: Blood
Blood (2009) 114 (22): 613.
https://doi.org/10.1182/blood.V114.22.613.613
Published: 2009
Journal Articles

Safety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myeloma

Clinical Trials & Observations
Paul Richardson, Sundar Jagannath, Mohamad Hussein, James Berenson, Seema Singhal, David Irwin, Stephanie F. Williams, William Bensinger, Ashraf Z. Badros, Robert Vescio, Laurie Kenvin, Zhinuan Yu, Marta Olesnyckyj, Jerome Zeldis, Robert Knight, Kenneth C. Anderson
Journal: Blood
Blood (2009) 114 (4): 772–778.
https://doi.org/10.1182/blood-2008-12-196238
Published: 2009
Journal Articles

Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure

Clinical Trials & Observations
Michael Wang, Meletios A. Dimopoulos, Christine Chen, M. Teresa Cibeira, Michel Attal, Andrew Spencer, S. Vincent Rajkumar, Zhinuan Yu, Marta Olesnyckyj, Jerome B. Zeldis, Robert D. Knight, Donna M. Weber
Journal: Blood
Blood (2008) 112 (12): 4445–4451.
https://doi.org/10.1182/blood-2008-02-141614
Published: 2008
Journal Articles

Relapsed/Refractory Multiple Myeloma Patients Treated with Lenalidomide/Dexamethasone Who Achieve a Complete or near Complete Response Have Longer Overall Survival and Time to Progression Compared with Patients Achieving a Partial Response.

Jean-Luc Harousseau, Donna Weber, Meletios Dimopoulos, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, David Siegel
Journal: Blood
Blood (2007) 110 (11): 3598.
https://doi.org/10.1182/blood.V110.11.3598.3598
Published: 2007
Journal Articles

Lenalidomide/Dexamethasone Improves Response and Prolongs Time to Progression, Even in Patients with IgA Multiple Myeloma: A Sub-Analysis of the MM-009/010 Studies.

Robert Foa, Donna Weber, Meletios Dimopoulos, Marta Olesnyckyj, Zhinuan Yu, Jerome Zeldis, Robert Knight, Asher Alban Chanan-Khan
Journal: Blood
Blood (2007) 110 (11): 4839.
https://doi.org/10.1182/blood.V110.11.4839.4839
Published: 2007
Journal Articles

Prolonged Overall Survival with Lenalidomide Plus Dexamethasone Compared with Dexamethasone Alone in Patients with Relapsed or Refractory Multiple Myeloma.

Donna Weber, Robert Knight, Christine Chen, Andrew Spencer, Zhinuan Yu, Jerome Zeldis, Marta Olesnyckyj, Meletios Dimopoulos
Journal: Blood
Blood (2007) 110 (11): 412.
https://doi.org/10.1182/blood.V110.11.412.412
Published: 2007