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Issue Archive

Volume 125, Issue 20
May 14 2015
Issue Cover

Table of Contents

EDITORIAL

Introduction to a series of reviews on multiple myeloma
Clinical Trials & Observations
Jesús F. San Miguel
View Articletitled, Introduction to a series of reviews on multiple myeloma

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Targets of opportunity for precision medicine
Yogen Saunthararajah
View Articletitled, Targets of opportunity for precision medicine
INSIDE BLOOD COMMENTARY
VWF fibers induce thrombosis during cancer
Lubor Borsig
View Articletitled, VWF fibers induce thrombosis during cancer
INSIDE BLOOD COMMENTARY
Fibronectin: extra domain brings extra risk?
Yiming Wang,Heyu Ni
View Articletitled, Fibronectin: extra domain brings extra risk?
INSIDE BLOOD COMMENTARY
Activating KIR: iN Kase of KIR-ligand mismatch
Nina Shah
View Articletitled, Activating KIR: iN Kase of KIR-ligand mismatch
INSIDE BLOOD COMMENTARY
HY antibodies as biomarkers for chronic GVHD
Tuna Mutis
View Articletitled, HY antibodies as biomarkers for chronic GVHD

REVIEW SERIES

Pathogenesis beyond the cancer clone(s) in multiple myeloma
Giada Bianchi,Nikhil C. Munshi
View Articletitled, Pathogenesis beyond the cancer clone(s) in multiple myeloma

REVIEW SERIES

New criteria for response assessment: role of minimal residual disease in multiple myeloma
Clinical Trials & Observations
Bruno Paiva,Jacques J. M. van Dongen,Alberto Orfao
View Articletitled, New criteria for response assessment: role of minimal residual disease in multiple myeloma

REVIEW SERIES

Smoldering multiple myeloma
Clinical Trials & Observations
S. Vincent Rajkumar,Ola Landgren,María-Victoria Mateos
View Articletitled, Smoldering multiple myeloma

REVIEW SERIES

Frontline therapy of multiple myeloma
Clinical Trials & Observations
Philippe Moreau,Michel Attal,Thierry Facon
View Articletitled, Frontline therapy of multiple myeloma

REVIEW SERIES

Treatment options for relapsed and refractory multiple myeloma
Clinical Trials & Observations
Ajay K. Nooka,Efstathios Kastritis,Meletios A. Dimopoulos,Sagar Lonial
View Articletitled, Treatment options for relapsed and refractory multiple myeloma

CLINICAL TRIALS AND OBSERVATIONS

Phase 1/2 study of carfilzomib plus melphalan and prednisone in patients aged over 65 years with newly diagnosed multiple myeloma
Clinical Trials & Observations
Philippe Moreau,Brigitte Kolb,Michel Attal,Denis Caillot,Lotfi Benboubker,Mourad Tiab,Cyrille Touzeau,Xavier Leleu,Murielle Roussel,Carine Chaleteix,Lucie Planche,Anne Chiffoleau,June Fortin,Hervé Avet-Loiseau,Jean-Yves Mary,Cyrille Hulin,Thierry Facon
View Articletitled, Phase 1/2 study of carfilzomib plus melphalan and prednisone in patients aged over 65 years with newly diagnosed multiple myeloma

HEMATOPOIESIS AND STEM CELLS

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo
Marioara F. Ciuculescu,Shin-Young Park,Kimberly Canty,Ronald Mathieu,Leslie E. Silberstein,David A. Williams
View Articletitled, Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo
Supplemental data
Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice
Brief Report
Ryan B. Day,Deepta Bhattacharya,Takashi Nagasawa,Daniel C. Link
View Articletitled, Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice
Supplemental data

LYMPHOID NEOPLASIA

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma
Rebecca L. Boddicker,N. Sertac Kip,Xiaoming Xing,Yu Zeng,Zhi-Zhang Yang,Jeong-Heon Lee,Luciana L. Almada,Sherine F. Elsawa,Ryan A. Knudson,Mark E. Law,Rhett P. Ketterling,Julie M. Cunningham,Yanhong Wu,Matthew J. Maurer,Megan M. O’Byrne,James R. Cerhan,Susan L. Slager,Brian K. Link,Julie C. Porcher,Deanna M. Grote,Diane F. Jelinek,Ahmet Dogan,Stephen M. Ansell,Martin E. Fernandez-Zapico,Andrew L. Feldman
View Articletitled, The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma
Supplemental data
Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia
Brief Report
Zachary A. Hing,Rose Mantel,Kyle A. Beckwith,Daphne Guinn,Erich Williams,Lisa L. Smith,Katie Williams,Amy J. Johnson,Amy M. Lehman,John C. Byrd,Jennifer A. Woyach,Rosa Lapalombella
View Articletitled, Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia
Supplemental data
The tumor virus landscape of AIDS-related lymphomas
e-blood
Aaron Arvey,Akinyemi I. Ojesina,Chandra Sekhar Pedamallu,Gianna Ballon,Joonil Jung,Fujiko Duke,Lorenzo Leoncini,Giulia De Falco,Eric Bressman,Wayne Tam,Amy Chadburn,Matthew Meyerson,Ethel Cesarman
View Articletitled, The tumor virus landscape of AIDS-related lymphomas
Supplemental data

MYELOID NEOPLASIA

Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach
Atsushi Nonami,Martin Sattler,Ellen Weisberg,Qingsong Liu,Jianming Zhang,Matthew P. Patricelli,Amanda L. Christie,Amy M. Saur,Nancy E. Kohl,Andrew L. Kung,Hojong Yoon,Taebo Sim,Nathanael S. Gray,James D. Griffin
View Articletitled, Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach
Supplemental data
IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells
Carolina Schinke,Orsolya Giricz,Weijuan Li,Aditi Shastri,Shanisha Gordon,Laura Barreyro,Tushar Bhagat,Sanchari Bhattacharyya,Nandini Ramachandra,Matthias Bartenstein,Andrea Pellagatti,Jacqueline Boultwood,Amittha Wickrema,Yiting Yu,Britta Will,Sheng Wei,Ulrich Steidl,Amit Verma
View Articletitled, IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells
Supplemental data

THROMBOSIS AND HEMOSTASIS

von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans
Alexander T. Bauer,Jan Suckau,Kathrin Frank,Anna Desch,Lukas Goertz,Andreas H. Wagner,Markus Hecker,Tobias Goerge,Ludmila Umansky,Philipp Beckhove,Jochen Utikal,Christian Gorzelanny,Nancy Diaz-Valdes,Viktor Umansky,Stefan W. Schneider
View Articletitled, von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans
Supplemental data
Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4
Prem Prakash,Paresh P. Kulkarni,Steven R. Lentz,Anil K. Chauhan
View Articletitled, Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4
Supplemental data

TRANSPLANTATION

Haploidentical hematopoietic transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality
Clinical Trials & Observations
Antonella Mancusi,Loredana Ruggeri,Elena Urbani,Antonio Pierini,Maria Speranza Massei,Alessandra Carotti,Adelmo Terenzi,Franca Falzetti,Antonella Tosti,Fabiana Topini,Silvia Bozza,Luigina Romani,Rita Tognellini,Martin Stern,Franco Aversa,Massimo F. Martelli,Andrea Velardi
View Articletitled, Haploidentical hematopoietic transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality
Supplemental data
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD
Dawn K. Reichenbach,Vincent Schwarze,Benjamin M. Matta,Victor Tkachev,Elisabeth Lieberknecht,Quan Liu,Brent H. Koehn,Dietmar Pfeifer,Patricia A. Taylor,Gabriele Prinz,Heide Dierbach,Natalie Stickel,Yvonne Beck,Max Warncke,Tobias Junt,Annette Schmitt-Graeff,Susumu Nakae,Marie Follo,Tobias Wertheimer,Lukas Schwab,Jason Devlin,Simon C. Watkins,Justus Duyster,James L. M. Ferrara,Heth R. Turnquist,Robert Zeiser,Bruce R. Blazar
View Articletitled, The IL-33/ST2 axis augments effector T-cell responses during acute GVHD
Supplemental data
Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans
Hideki Nakasone,Lu Tian,Bita Sahaf,Takakazu Kawase,Kelsi Schoenrock,Spenser Perloff,Christine E. Ryan,Jed Paul,Rakesh Popli,Fang Wu,Joanne M. Otani,John Coller,Edus H. Warren, III,David B. Miklos
View Articletitled, Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans
Supplemental data

VASCULAR BIOLOGY

Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs
Makon-Sébastien Njock,Henry S. Cheng,Lan T. Dang,Maliheh Nazari-Jahantigh,Andrew C. Lau,Emilie Boudreau,Mark Roufaiel,Myron I. Cybulsky,Andreas Schober,Jason E. Fish
View Articletitled, Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs
Supplemental data

BLOOD WORK

Lymphoma and gout coexisting in the same joint fluid
Valerie A. Arboleda,Stephen Lee
View Articletitled, Lymphoma and gout coexisting in the same joint fluid
All Issues

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