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Zachary A. Hing
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Journal Articles

Dysregulation of PRMT5 in Chronic Lymphocytic Leukemia Supports Transformation to Diffuse Large B-Cell Lymphoma

Ethan Whipp, Zachary A Hing, Janek S. Walker, Steven Sher, Casey B. Cempre, Fiona Brown, Claudio Agostinelli, Stefano A Pileri, Katie Williams, Larry Beaver, Alexander Pan, Charles T. Gregory, Pearlly S. Yan, Peggy Scherle, Min Wang, Kris Vaddi, Selina Chen-Kiang, Jennifer A. Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, Robert A. Baiocchi, Bradley W Blaser, Rosa Lapalombella
Journal: Blood
Blood (2022) 140 (Supplement 1): 8746–8747.
https://doi.org/10.1182/blood-2022-169949
Published: 2022
Journal Articles

PRMT5 Initiates an Epigenetic Program That Promotes Progression of Chronic Lymphocytic Leukemia

Zachary A Hing, BS, Jordan N. Skinner, B.S., Larry P. Beaver, Tzung-Huei Lai, PhD, Casey B. Cempre, B.S., Bonnie K. Harrington, DVM, Deepa Sampath, PhD, Amy M. Lehman, PhD, Lianbo Yu, PhD, Lapo Alinari, MD PhD, John C. Byrd, MD, Robert A Baiocchi, MD PhD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2487.
https://doi.org/10.1182/blood.V130.Suppl_1.2487.2487
Published: 2017
Journal Articles

Exploring the Role of the Recurrent Exportin 1 (XPO1/CRM1) Mutations E571G and E571K in Chronic Lymphocytic Leukemia

Zachary A. Hing, BS, James S. Blachly, MD, Virginia M. Goettl, DVM, PhD, Guramrit Singh, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2016) 128 (22): 972.
https://doi.org/10.1182/blood.V128.22.972.972
Published: 2016
Journal Articles

Next Generation XPO1 Inhibitor Shows Improved Efficacy and In Vivo Tolerability in Hematologic Malignancies

Zachary A. Hing, BS, Ho Yee Joyce Fung, BA, Parvathi Ranganathan, PhD, Shaneice Mitchell, BS, Dalia El-Gamal, PhD, Jennifer A. Woyach, MD, Katie Williams, MS, Virginia M. Goettl, DVM, PhD, Jordan L. Smith, BS, Xueyan Yu, Xiaomei Meng, Qingxiang Sun, PhD, Tolga Cagatay, PhD, John B. MacMillan, PhD, Amy M. Lehman, MAS, David M. Lucas, PhD, Erkan Baloglu, PhD, Sharon Shacham, Michael Kauffman, MD PhD, John C. Byrd, MD, Yuh Min Chook, PhD, Ramiro Garzon, MD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2015) 126 (23): 317.
https://doi.org/10.1182/blood.V126.23.317.317
Published: 2015
Journal Articles

A Novel Inhibitor of BET Family Bromodomains Demonstrates In Vivo and I n Vi tro Potency in B-Cell Malignancies

Dalia El-Gamal, PhD, Zachary A. Hing, BS, Shaneice Mitchell, BS, Taylor D. LaFollette, Paul J. Brennan, Joseph M. Flynn, DO, MPH, Jeffrey A. Jones, MD MPH, Farrukh Awan, MD MS, Leslie A. Andritsos, MD, James S. Blachly, MD, Katie Williams, MS, Bonnie K. Harrington, DVM, Virginia M. Goettl, DVM, PhD, Jennifer A. Woyach, MD, Amy M. Lehman, MAS, Lianbo Yu, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2015) 126 (23): 318.
https://doi.org/10.1182/blood.V126.23.318.318
Published: 2015
Journal Articles

Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia

Brief Report
Zachary A. Hing, Rose Mantel, Kyle A. Beckwith, Daphne Guinn, Erich Williams, Lisa L. Smith, Katie Williams, Amy J. Johnson, Amy M. Lehman, John C. Byrd, Jennifer A. Woyach, Rosa Lapalombella
Journal: Blood
Blood (2015) 125 (20): 3128–3132.
https://doi.org/10.1182/blood-2015-01-621391
Published: 2015
Includes: Supplemental data
Journal Articles

Single-Nucleotide Variations Defining Previously Unreported ADAMTS13 Haplotypes Are Associated With Differential Expression and Activity Of The VWF-Cleaving Protease In a Salvadoran Congenital Thrombotic Thrombocytopenic Purpura Family

Benjamin Kim, M.D., M.Phil., Zachary A. Hing, Andrew Wu, Tal Schiller, Evi B. Struble, Ph.D., David Liuwantara, Ph.D., Pamela H. Kempert, M.D., Eric J. Broxham, M.D., Nathan C. Edwards, Victor J. Marder, M.D., Vijaya L. Simhadri, Ph.D., Zuben E. Sauna, Ph.D., Tom E. Howard, M.D., Ph.D., Chava Kimchi-Sarfaty, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2319.
https://doi.org/10.1182/blood.V122.21.2319.2319
Published: 2013