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Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Blood (2018) 132 (Supplement 1): 4344.

https://doi.org/10.1182/blood-2018-99-113881

Published: 2018

Journal Articles

Gene Expression Profiling Identifies Distinct Signatures for Dysplastic and Proliferative Chronic Myelomonocytic Leukemia

Mrinal M Patnaik, MBBS, Daniela Barraco, MD, Terra L. Lasho, PhD, Ezequiel Tolosa, PhD, Luciana L. Almada, PhD, Jaime I Davila, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, MD, Éric Solary, MD PhD, Nathalie M. Droin, PhD, Naseema Gangat, MBBS, Aref Al-Kali, MD, Martin E. Fernandez-Zapico, MD, Ayalew Tefferi, MD

Blood (2016) 128 (22): 110.

https://doi.org/10.1182/blood.V128.22.110.110

Published: 2016

Journal Articles

Number and Type of TET2 Mutations in Chronic Myelomonocytic Leukemia: Clinical and Prognostic Correlates

Mrinal M Patnaik, MBBS, Mohammad Faizan Zahid, Terra L. Lasho, PhD, Ezequiel Tolosa, PhD, Christy Finke, BS, Curtis A. Hanson, MD, Rhett P. Ketterling, MD, Eric Solary, MD Prof, Keith D Robertson, PhD, Naseema Gangat, MBBS, Martin E. Fernandez-Zapico, MD, Ayalew Tefferi, MD

Blood (2016) 128 (22): 4343.

https://doi.org/10.1182/blood.V128.22.4343.4343

Published: 2016

Journal Articles

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Seongseok Yun, Nicole D. Vincelette, Katherine L. B. Knorr, Luciana L. Almada, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, Haiming Dai, Keith W. Pratz, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Andrea E. Wahner Hendrickson, Martin E. Fernandez-Zapico, Scott H. Kaufmann

Blood (2016) 127 (22): 2711–2722.

https://doi.org/10.1182/blood-2015-02-629485

Published: 2016

Includes: Supplemental data

Journal Articles

mTOR Dual Inhibitor Induced Cytotoxicity Depends on 4EBP1/c-Myc/Puma and NFkB/Egr-1/Bim Pathways in Human Lymphoid Malignancies

Seongseok Yun, MD PhD, Nicole D. Vincelette, Katherine L. B. Knorr, PhD, Luciana L. Almada, PhD, Paula A. Schneider, Kevin L. Peterson, PhD, Karen S. Flatten, Allan D. Hess, PhD, B. Douglas Smith, MD, Judith E. Karp, MD, Martin E. Fernandez-Zapico, MD, Scott H. Kaufmann, MD PhD

Blood (2015) 126 (23): 3705.

https://doi.org/10.1182/blood.V126.23.3705.3705

Published: 2015

Journal Articles

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

Blood (2015) 125 (20): 3118–3127.

https://doi.org/10.1182/blood-2014-05-578575

Published: 2015

Includes: Supplemental data

Journal Articles

A Novel Mechanism of GLI2 Mediated Regulation of IgM Secretion in Waldenström Macroglobulinemia

David A. Jackson, Timothy D. Smith, MS, Nansalmaa Amarsaikhan, PhD, Ann Vrabel, Ezequiel Tolosa, PhD, Luciana L. Almada, PhD, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD

Blood (2014) 124 (21): 3006.

https://doi.org/10.1182/blood.V124.21.3006.3006

Published: 2014

Journal Articles

The Transcription Factor GLI3 Is a Novel Candidate Effector Of Toll-Like Receptor 4 (TLR4) Signaling In Monocytes

Shannon K. Boi, BS, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD

Blood (2013) 122 (21): 2269.

https://doi.org/10.1182/blood.V122.21.2269.2269

Published: 2013

Journal Articles

GLI2 Transcription Factor Modulates CD40 Ligand Expression In Bone Marrow Stromal Cells

Matthew S. Neil, BS, Joel R. Dennison, Martin E. Fernandez-Zapico, MD, Sherine F. Elsawa, PhD

Blood (2013) 122 (21): 4271.

https://doi.org/10.1182/blood.V122.21.4271.4271

Published: 2013

Journal Articles

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

Sherine F. Elsawa, Anne J. Novak, Steven C. Ziesmer, Luciana L. Almada, Lucy S. Hodge, Deanna M. Grote, Thomas E. Witzig, Martin E. Fernandez-Zapico, Stephen M. Ansell

Blood (2011) 118 (20): 5540–5549.

https://doi.org/10.1182/blood-2011-04-351742

Published: 2011

Journal Articles

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target In Mantle Cell Lymphoma

Elena Beltran, PhD, Vicente Fresquet, PhD, Javier Martinez-Useros, Jose A. Richter-Larrea, PhD, Ainara Sagardoy, PhD, Izaskun Sesma, Luciana L. Almada, PhD, Santiago Montes-Moreno, MD, Stefan Gesk, MD, Reiner Siebert, Prof., Dr., med., MaJose Calasanz, PhD, Felipe Prosper, MD, Miguel A. Piris, MD, Martin E. Fernandez-Zapico, MD, Jose A Martinez-Climent, MD, PhD

Blood (2010) 116 (21): 769.

https://doi.org/10.1182/blood.V116.21.769.769

Published: 2010

Journal Articles

GLI2, An Effector of the Hedgehog Pathway, Is a Novel Regulator of IL6 Oncogenic Function In the Tumor Microenvironment

Sherine F. Elsawa, PhD, Luciana L. Almada, PhD, Steven Ziesmer, Thomas E. Witzig, MD, Stephen M. Ansell, MD, PhD, Martin E. Fernandez-Zapico, MD

Blood (2010) 116 (21): 613.

https://doi.org/10.1182/blood.V116.21.613.613

Published: 2010

Journal Articles

Comprehensive Analysis of the Waldenström Macroglobulinemia “Cytokine Milieu” Reveals a Novel Role of Rantes Signaling in the Regulation of Immunoglobulin Production

Sherine F. Elsawa, PhD, Anne J. Novak, Ph.D., Steven C Ziesmer, Luciana L Almada, Ph.D., Martin E Fernandez-Zapico, M.D., Thomas E Witzig, M.D., Stephen M. Ansell, M.D./Ph.D.

Blood (2008) 112 (11): 618.

https://doi.org/10.1182/blood.V112.11.618.618

Published: 2008

Journal Articles

Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor κB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

Andrei V. Ougolkov, Nancy D. Bone, Martin E. Fernandez-Zapico, Neil E. Kay, Daniel D. Billadeau

Blood (2007) 110 (2): 735–742.

https://doi.org/10.1182/blood-2006-12-060947

Published: 2007

NARROW

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Gene Expression Profiling Identifies Distinct Signatures for Dysplastic and Proliferative Chronic Myelomonocytic Leukemia

Number and Type of TET2 Mutations in Chronic Myelomonocytic Leukemia: Clinical and Prognostic Correlates

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

mTOR Dual Inhibitor Induced Cytotoxicity Depends on 4EBP1/c-Myc/Puma and NFkB/Egr-1/Bim Pathways in Human Lymphoid Malignancies

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma

A Novel Mechanism of GLI2 Mediated Regulation of IgM Secretion in Waldenström Macroglobulinemia

The Transcription Factor GLI3 Is a Novel Candidate Effector Of Toll-Like Receptor 4 (TLR4) Signaling In Monocytes

GLI2 Transcription Factor Modulates CD40 Ligand Expression In Bone Marrow Stromal Cells

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target In Mantle Cell Lymphoma

GLI2, An Effector of the Hedgehog Pathway, Is a Novel Regulator of IL6 Oncogenic Function In the Tumor Microenvironment

Comprehensive Analysis of the Waldenström Macroglobulinemia “Cytokine Milieu” Reveals a Novel Role of Rantes Signaling in the Regulation of Immunoglobulin Production

Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor κB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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