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Journal Articles

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Seongseok Yun, Nicole D. Vincelette, Katherine L. B. Knorr, Luciana L. Almada, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, Haiming Dai, Keith W. Pratz, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Andrea E. Wahner Hendrickson, Martin E. Fernandez-Zapico, Scott H. Kaufmann

Blood (2016) 127 (22): 2711–2722.

https://doi.org/10.1182/blood-2015-02-629485

Published: 2016

Includes: Supplemental data

Journal Articles

MTH1 Inhibitor-Induced Cytotoxicity in Acute Myeloid Leukemia

Mithun Vinod Shah, MD PhD, Karen S. Flatten, B. Douglas Smith, MD, Allan D. Hess, PhD, Scott H. Kaufmann, MD PhD

Blood (2015) 126 (23): 1273.

https://doi.org/10.1182/blood.V126.23.1273.1273

Published: 2015

Journal Articles

mTOR Dual Inhibitor Induced Cytotoxicity Depends on 4EBP1/c-Myc/Puma and NFkB/Egr-1/Bim Pathways in Human Lymphoid Malignancies

Seongseok Yun, MD PhD, Nicole D. Vincelette, Katherine L. B. Knorr, PhD, Luciana L. Almada, PhD, Paula A. Schneider, Kevin L. Peterson, PhD, Karen S. Flatten, Allan D. Hess, PhD, B. Douglas Smith, MD, Judith E. Karp, MD, Martin E. Fernandez-Zapico, MD, Scott H. Kaufmann, MD PhD

Blood (2015) 126 (23): 3705.

https://doi.org/10.1182/blood.V126.23.3705.3705

Published: 2015

Journal Articles

Investigation of MLN4924 Alone and in Combination with Bcl-2 Inhibitors in Hematopoietic Stem Cells and Progenitors in Acute Myelogenous Leukemia

Katherine L. B. Knorr, B. Douglas Smith, MD, Allan D. Hess, PhD, Judith E. Karp, MD, Scott H. Kaufmann, MD PhD

Blood (2014) 124 (21): 3603.

https://doi.org/10.1182/blood.V124.21.3603.3603

Published: 2014

Journal Articles

Induction Of In Vivo Oligoclonal T Cell Expansion and Specific In Vitro T Cell Responses Following K562/GM-CSF Vaccination Of MDS Patients

Gabrielle Prince, Chris Thoburn, Erica D. Warlick, MD, Allan D. Hess, PhD, B. Douglas Smith, MD

Blood (2013) 122 (21): 2811.

https://doi.org/10.1182/blood.V122.21.2811.2811

Published: 2013

Journal Articles

Equal opportunity targeting in chronic GVHD

Allan D. Hess

Blood (2012) 119 (26): 6183–6184.

https://doi.org/10.1182/blood-2012-04-425298

Published: 2012

Journal Articles

Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies

Mamta Gupta, Andrea E. Wahner Hendrickson, Seong Seok Yun, Jing Jing Han, Paula A. Schneider, Brian D. Koh, Mary J. Stenson, Linda E. Wellik, Jennifer C. Shing, Kevin L. Peterson, Karen S. Flatten, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Sharon Barr, Thomas E. Witzig, Scott H. Kaufmann

Blood (2012) 119 (2): 476–487.

https://doi.org/10.1182/blood-2011-04-346601

Published: 2012

Includes: Supplemental data

Journal Articles

Favorable Immune Reconstitution After Nonmyeloablative, T-Cell Replete, HLA-Haploidentical BMT with Post-Transplant Cyclophosphamide

Heather J. Symons, Chimene Kesserwan, MD, Ferdynand Kos, PhD, Christopher J. Thoburn, MsC, Ashley T. Munchel, MD, Wendy Ying, BA, Leo Luznik, Hyam I. Levitsky, MD, Richard J. Jones, MD, Allan D. Hess, PhD, Ephraim J. Fuchs

Blood (2011) 118 (21): 1009.

https://doi.org/10.1182/blood.V118.21.1009.1009

Published: 2011

Journal Articles

Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells

Christopher G. Kanakry, Allan D. Hess, Christopher D. Gocke, Christopher Thoburn, Ferdynand Kos, Christian Meyer, Janet Briel, Leo Luznik, B. Douglas Smith, Hyam Levitsky, Judith E. Karp

Blood (2011) 117 (2): 608–617.

https://doi.org/10.1182/blood-2010-04-277939

Published: 2011

Journal Articles

Separation of GVHD and GVL

Allan D. Hess

Blood (2010) 115 (9): 1666–1667.

https://doi.org/10.1182/blood-2009-11-254946

Published: 2010

Journal Articles

Immune Recovery after Timed Sequential Therapy in Acute Myelogenous Leukemia: Discordant Recovery of Naïve T Lymphocytes and Antigen Driven Regulatory T Cells.

Allan D. Hess, PhD, Christian Meyer, Christopher Thoburn, Ferdynand Kos, Christopher Gocke, Hyam Levitsky, Judith Karp

Blood (2008) 112 (11): 947.

https://doi.org/10.1182/blood.V112.11.947.947

Published: 2008

Journal Articles

Regulatory T cells and the pursuit of self-tolerance

Allan D. Hess

Blood (2007) 110 (10): 3497–3498.

https://doi.org/10.1182/blood-2007-08-107920

Published: 2007

Journal Articles

Donor Foxp3-positive T cells: the missing link

Allan D. Hess

Blood (2006) 108 (4): 1121–1122.

https://doi.org/10.1182/blood-2006-06-025932

Published: 2006

Journal Articles

Chronic graft-versus-host disease: a breakdown of self-tolerance?

Allan D. Hess

Blood (2005) 105 (12): 4548–4549.

https://doi.org/10.1182/blood-2005-03-1262

Published: 2005

Journal Articles

Antigen Specificity and Immunoregulation in Syngeneic Graft-Versus-Host Disease.

Allan D. Hess, Ph.D., Christopher J. Thoburn, B.S., Emilie C. Bright, B.S., Yuji Miura, M.D., Ph.D.

Blood (2004) 104 (11): 4973.

https://doi.org/10.1182/blood.V104.11.4973.4973

Published: 2004

Journal Articles

T Cell Activation and Regulation in Graft-Versus-Host Disease: Integral Role of CD28, CTLA4 and GITR Splice Variants.

Yuji Miura, Christopher J. Thoburn, Emilie C. Bright, Elizabeth C. Matsui, William H. Matsui, Richard J. Jones, Allan D. Hess

Blood (2004) 104 (11): 3054.

https://doi.org/10.1182/blood.V104.11.3054.3054

Published: 2004

Journal Articles

Association of Foxp3 regulatory gene expression with graft-versus-host disease

Yuji Miura, Christopher J. Thoburn, Emilie C. Bright, Michele L. Phelps, Tahiro Shin, Elizabeth C. Matsui, William H. Matsui, Sally Arai, Ephraim J. Fuchs, Georgia B. Vogelsang, Richard J. Jones, Allan D. Hess

Blood (2004) 104 (7): 2187–2193.

https://doi.org/10.1182/blood-2004-03-1040

Published: 2004

Journal Articles

Cytokine and chemokine profiles in autologous graft-versus-host disease (GVHD): interleukin 10 and interferon γ may be critical mediators for the development of autologous GVHD

Yuji Miura, Christopher J. Thoburn, Emilie C. Bright, Weiran Chen, Shinji Nakao, Allan D. Hess

Blood (2002) 100 (7): 2650–2658.

https://doi.org/10.1182/blood-2002-01-0176

Published: 2002

Journal Articles

Characterization of the T-cell repertoire in autologous graft-versus-host disease (GVHD): evidence for the involvement of antigen-driven T-cell response in the development of autologous GVHD

Yuji Miura, Christopher J. Thoburn, Emilie C. Bright, Matthias Sommer, Susan Lefell, Mikio Ueda, Shinji Nakao, Allan D. Hess

Blood (2001) 98 (3): 868–876.

https://doi.org/10.1182/blood.V98.3.868

Published: 2001

Journal Articles

Specificity of Effector T Lymphocytes in Autologous Graft-Versus-Host Disease: Role of the Major Histocompatibility Complex Class II Invariant Chain Peptide

Allan D. Hess, Emilie C. Bright, Christopher Thoburn, Georgia B. Vogelsang, Richard J. Jones, M. John Kennedy

Blood (1997) 89 (6): 2203–2209.

https://doi.org/10.1182/blood.V89.6.2203

Published: 1997

NARROW

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

MTH1 Inhibitor-Induced Cytotoxicity in Acute Myeloid Leukemia

mTOR Dual Inhibitor Induced Cytotoxicity Depends on 4EBP1/c-Myc/Puma and NFkB/Egr-1/Bim Pathways in Human Lymphoid Malignancies

Investigation of MLN4924 Alone and in Combination with Bcl-2 Inhibitors in Hematopoietic Stem Cells and Progenitors in Acute Myelogenous Leukemia

Induction Of In Vivo Oligoclonal T Cell Expansion and Specific In Vitro T Cell Responses Following K562/GM-CSF Vaccination Of MDS Patients

Equal opportunity targeting in chronic GVHD

Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies

Favorable Immune Reconstitution After Nonmyeloablative, T-Cell Replete, HLA-Haploidentical BMT with Post-Transplant Cyclophosphamide

Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells

Separation of GVHD and GVL

Immune Recovery after Timed Sequential Therapy in Acute Myelogenous Leukemia: Discordant Recovery of Naïve T Lymphocytes and Antigen Driven Regulatory T Cells.

Regulatory T cells and the pursuit of self-tolerance

Donor Foxp3-positive T cells: the missing link

Chronic graft-versus-host disease: a breakdown of self-tolerance?

Antigen Specificity and Immunoregulation in Syngeneic Graft-Versus-Host Disease.

T Cell Activation and Regulation in Graft-Versus-Host Disease: Integral Role of CD28, CTLA4 and GITR Splice Variants.

Association of Foxp3 regulatory gene expression with graft-versus-host disease

Cytokine and chemokine profiles in autologous graft-versus-host disease (GVHD): interleukin 10 and interferon γ may be critical mediators for the development of autologous GVHD

Characterization of the T-cell repertoire in autologous graft-versus-host disease (GVHD): evidence for the involvement of antigen-driven T-cell response in the development of autologous GVHD

Specificity of Effector T Lymphocytes in Autologous Graft-Versus-Host Disease: Role of the Major Histocompatibility Complex Class II Invariant Chain Peptide

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American Society of Hematology

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American Society of Hematology

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