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Neonatal GATA1 mutant clones under the radar
Prospective cohort study comparing intravenous busulfan to total body irradiation in hematopoietic cell transplantation
The ASH Choosing Wisely® campaign: five hematologic tests and treatments to question
GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia
Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model
Issue Archive
December 5 2013
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS & OBSERVATIONS
Neonatal GATA1 mutant clones under the radar
Clinical Trials & Observations
BLOOD WORK
PLENARY PAPER
Better leukemia-free and overall survival in AML in first remission following cyclophosphamide in combination with busulfan compared with TBI
Edward A. Copelan,Betty K. Hamilton,Belinda Avalos,Kwang Woo Ahn,Brian J. Bolwell,Xiaochun Zhu,Mahmoud Aljurf,Koen van Besien,Christopher Bredeson,Jean-Yves Cahn,Luciano J. Costa,Marcos de Lima,Robert Peter Gale,Gregory A. Hale,Joerg Halter,Mehdi Hamadani,Yoshihiro Inamoto,Rammurti T. Kamble,Mark R. Litzow,Alison W. Loren,David I. Marks,Eduardo Olavarria,Vivek Roy,Mitchell Sabloff,Bipin N. Savani,Matthew Seftel,Harry C. Schouten,Celalettin Ustun,Edmund K. Waller,Daniel J. Weisdorf,Baldeep Wirk,Mary M. Horowitz,Mukta Arora,Jeff Szer,Jorge Cortes,Matt E. Kalaycio,Richard T. Maziarz,Wael Saber
PLENARY PAPER
Prospective cohort study comparing intravenous busulfan to total body irradiation in hematopoietic cell transplantation
Clinical Trials & Observations
Christopher Bredeson,Jennifer LeRademacher,Kazunobu Kato,John F. DiPersio,Edward Agura,Steven M. Devine,Frederick R. Appelbaum,Marcie R. Tomblyn,Ginna G. Laport,Xiaochun Zhu,Philip L. McCarthy,Vincent T. Ho,Kenneth R. Cooke,Elizabeth Armstrong,Angela Smith,J. Douglas Rizzo,Jeanne M. Burkart,Marcelo C. Pasquini
PERSPECTIVES
The ASH Choosing Wisely® campaign: five hematologic tests and treatments to question
Clinical Trials & Observations
Lisa K. Hicks,Harriet Bering,Kenneth R. Carson,Judith Kleinerman,Vishal Kukreti,Alice Ma,Brigitta U. Mueller,Sarah H. O'Brien,Marcelo Pasquini,Ravindra Sarode,Lawrence Solberg, Jr,Adam E. Haynes,Mark A. Crowther
REVIEW ARTICLE
REVIEW SERIES
CLINICAL TRIALS AND OBSERVATIONS
GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia
Clinical Trials & Observations
Irene Roberts,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Kate Alford,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Georgina Hall,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Gaetan Juban,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Helen Richmond,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Alice Norton,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Grant Vallance,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Kelly Perkins,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Emanuele Marchi,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Simon McGowan,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Anindita Roy,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Gillian Cowan,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Mark Anthony,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Amit Gupta,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,John Ho,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Sabita Uthaya,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Anna Curley,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Shree Vishna Rasiah,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Timothy Watts,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Richard Nicholl,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Alison Bedford-Russell,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Raoul Blumberg,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Angela Thomas,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Brenda Gibson,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Chris Halsey,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Pek-Wan Lee,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Sunit Godambe,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Connor Sweeney,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Neha Bhatnagar,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Anne Goriely,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Peter Campbell,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group,Paresh Vyas,on behalf of the Oxford-Imperial Down Syndrome Cohort Study Group
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts
Lucinda J. Berglund,Danielle T. Avery,Cindy S. Ma,Leen Moens,Elissa K. Deenick,Jacinta Bustamante,Stephanie Boisson-Dupuis,Melanie Wong,Stephen Adelstein,Peter D. Arkwright,Rosa Bacchetta,Liliana Bezrodnik,Harjit Dadi,Chaim M. Roifman,David A. Fulcher,John B. Ziegler,Joanne M. Smart,Masao Kobayashi,Capucine Picard,Anne Durandy,Matthew C. Cook,Jean-Laurent Casanova,Gulbu Uzel,Stuart G. Tangye
LYMPHOID NEOPLASIA
Rituximab maintenance after first-line therapy with rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) for chronic lymphocytic leukemia
Pau Abrisqueta,Neus Villamor,María José Terol,Eva González-Barca,Marcos González,Christelle Ferrà,Eugenia Abella,Julio Delgado,Jose A. García-Marco,Yolanda González,Felix Carbonell,Secundino Ferrer,Encarna Monzó,Isidro Jarque,Ana Muntañola,Mireia Constants,Lourdes Escoda,Xavier Calvo,Sabela Bobillo,José Bruno Montoro,Emili Montserrat,Francesc Bosch
Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model
Brief Report
Valeria Lascano,Marco Guadagnoli,Jan G. Schot,Dieuwertje M. Luijks,Jeroen E. J. Guikema,Katherine Cameron,Michael Hahne,Steven Pals,Erik Slinger,Thomas J. Kipps,Marinus H. J. van Oers,Eric Eldering,Jan Paul Medema,Arnon P. Kater
RED CELLS, IRON, AND ERYTHROPOIESIS
TRANSPLANTATION
Longitudinal trajectory of sexual functioning after hematopoietic cell transplantation: impact of chronic graft-versus-host disease and total body irradiation
F. Lennie Wong,Liton Francisco,Kayo Togawa,Heeyoung Kim,Alysia Bosworth,Liezl Atencio,Cara Hanby,Marcia Grant,Fouad Kandeel,Stephen J. Forman,Smita Bhatia
VASCULAR BIOLOGY
Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature
Xabier L. Aranguren,Xabier Agirre,Manu Beerens,Giulia Coppiello,Maialen Uriz,Ine Vandersmissen,Mohammed Benkheil,Joaquin Panadero,Natalia Aguado,Alberto Pascual-Montano,Victor Segura,Felipe Prósper,Aernout Luttun
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Cover Image
Cover Image
Photomicrograph of erythrocyte morphologic abnormalities on a blood smear from a neonate with Down syndrome showing dyserythropoietic normoblasts and basophilic stippling. Trilineage dysplasia of peripheral blood cells is seen in almost all neonates with Down syndrome. See the article by Roberts et al on page 3908.
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