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Gillian Cowan
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Journal Articles

Developmental Stage Specific B-Progenitor Expansion in Normal Fetal Bone Marrow Is Absent in Down Syndrome: Implications for Infant ALL

Anindita Roy, MDPhD, Georg Bohn, Katerina Goudevenou, Gillian Cowan, Neha Bhatnagar, David O'Connor, Oliver Tunstall, Jerry Chan, Phillip Bennett, Sailesh Kumar, Deena Iskander, Sarah Inglott, Binbin Liu, Philip Ancliff, Anastasios Karadimitris, Irene Roberts, MDFRCP FRCPCH FRCPath
Journal: Blood
Blood (2014) 124 (21): 4331.
https://doi.org/10.1182/blood.V124.21.4331.4331
Published: 2014
Journal Articles

Trisomy 21-Associated Abnormalities in IGF Signalling and the Fetal Microenvironment Both Contribute to Disruption of Fetal Hematopoiesis in Down Syndrome

David O'Connor, Binbin Liu, Gillian Cowan, Anindita Roy, MDPhD, Katerina Goudevenou, Neha Bhatnagar, MBChB MRCPCH FRCPath, Oliver Tunstall, Josu de la Fuente, PhD FRCP, MRCPCH, FRCPath, Anastasios Karadimitris, Irene Roberts, MDFRCP FRCPCH FRCPath
Journal: Blood
Blood (2014) 124 (21): 1885.
https://doi.org/10.1182/blood.V124.21.1885.1885
Published: 2014
Journal Articles

GATA1 -mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

Clinical Trials & Observations
Irene Roberts, Kate Alford, Georgina Hall, Gaetan Juban, Helen Richmond, Alice Norton, Grant Vallance, Kelly Perkins, Emanuele Marchi, Simon McGowan, Anindita Roy, Gillian Cowan, Mark Anthony, Amit Gupta, John Ho, Sabita Uthaya, Anna Curley, Shree Vishna Rasiah, Timothy Watts, Richard Nicholl, Alison Bedford-Russell, Raoul Blumberg, Angela Thomas, Brenda Gibson, Chris Halsey, Pek-Wan Lee, Sunit Godambe, Connor Sweeney, Neha Bhatnagar, Anne Goriely, Peter Campbell, Paresh Vyas
Journal: Blood
Blood (2013) 122 (24): 3908–3917.
https://doi.org/10.1182/blood-2013-07-515148
Published: 2013
Includes: Supplemental data
Journal Articles

Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma

Aristeidis Chaidos, Chris P. Barnes, Gillian Cowan, Philippa C. May, Valeria Melo, Evdoxia Hatjiharissi, Maria Papaioannou, Heather Harrington, Helen Doolittle, Evangelos Terpos, Meletios Dimopoulos, Saad Abdalla, Helen Yarranton, Kikkeri Naresh, Letizia Foroni, Alistair Reid, Amin Rahemtulla, Michael Stumpf, Irene Roberts, Anastasios Karadimitris
Journal: Blood
Blood (2013) 121 (2): 318–328.
https://doi.org/10.1182/blood-2012-06-436220
Published: 2013
Includes: Supplemental data
Journal Articles

Clinical Drug Resistance Linked to Inter-Convertible Phenotypic and Functional States of Tumor-Propagating Cells in Multiple Myeloma.

Aristeidis Chaidos, MD, PhD, Chris P Barnes, Gillian Cowan, Philippa May, Valeria Melo, Evdoxia Hatjiharissi, Maria Papaioannou, Heather Harrington, Helen Doolittle, Evangelos Terpos, Meletios A Dimopoulos, MD, Saad Abdalla, Helen Yarranton, Kikkeri Naresh, Letizia Foroni, Alistair Reid, PhD, Amin Rahemtulla, Michael Stumpf, Irene Roberts, Anastasios Karadimitris, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2909.
https://doi.org/10.1182/blood.V120.21.2909.2909
Published: 2012
Journal Articles

Gene-Selective Histone Hyperacetylation and Enhanced Sp1 Occupancy Underpin Transcriptional Modulation of Genes of the Glycolytic-Pentose Phosphate Pathway in Response to Histone Deacetylase Inhibitors - Therapeutic Implications

Kalliopi Makarona, Valentina Caputo, David Roper, Joana Costa, Gillian Cowan, Aristeidis Chaidos, David O'Connor, Elisabeth Georgiou, Maria Papaioannou, Mark Layton, Irene Roberts, Anastasios Karadimitris
Journal: Blood
Blood (2012) 120 (21): 977.
https://doi.org/10.1182/blood.V120.21.977.977
Published: 2012
Journal Articles

Trilineage Perturbation of Hematopoiesis In Neonates with Down Syndrome

Alice Norton, MB, Georgina Hall, BSc, PhD, MBBS, FRCP, FRCPath, Helen Richmond, RN, Anindita Roy, MB, Gillian Cowan, PhD, Kate Alford, PhD, Keelin O'Donoghue, MB, PhD, Oliver Tunstall, MB, PhD, Aristeidis Chaidos, MD, PhD, Anastasios Karadimitris, MD, PhD, Paresh Vyas, MB, PhD, Irene Roberts, MD
Journal: Blood
Blood (2010) 116 (21): 876.
https://doi.org/10.1182/blood.V116.21.876.876
Published: 2010