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Edward M. Conway
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Journal Articles

Biomaterial and cellular implants: foreign surfaces where immunity and coagulation meet

Jayachandran N. Kizhakkedathu, Edward M. Conway
Journal: Blood
Blood (2022) 139 (13): 1987–1998.
https://doi.org/10.1182/blood.2020007209
Published: 2022
Journal Articles

Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency

Amy W. Strilchuk, Scott C. Meixner, Jerry Leung, Nooshin S. Safikhan, Jayesh A. Kulkarni, Hannah M. Russell, Roy van der Meel, Michael R. Sutherland, A. Phillip Owens, III, Joseph S. Palumbo, Edward M. Conway, Edward L. G. Pryzdial, Pieter R. Cullis, Christian J. Kastrup
Journal: Blood
Blood (2020) 136 (25): 2946–2954.
https://doi.org/10.1182/blood.2020004976
Published: 2020
Includes: Supplemental data
Journal Articles

Exploring traditional and nontraditional roles for thrombomodulin

Houra Loghmani, Edward M. Conway
Journal: Blood
Blood (2018) 132 (2): 148–158.
https://doi.org/10.1182/blood-2017-12-768994
Published: 2018
Journal Articles

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA

Manu Thomas Kalathottukaren, Libin Abraham, Piyushkumar R. Kapopara, Benjamin F. L. Lai, Rajesh A. Shenoi, Federico I. Rosell, Edward M. Conway, Edward L. G. Pryzdial, James H. Morrissey, Charles A. Haynes, Jayachandran N. Kizhakkedathu
Journal: Blood
Blood (2017) 129 (10): 1368–1379.
https://doi.org/10.1182/blood-2016-10-747915
Published: 2017
Includes: Supplemental data
Journal Articles

Antiphospholipid Syndrome (APS) Patient Plasmas Consistently Activate Complement: A Novel Approach to Detecting a Pathogenic Mechanism for APS

Jacob H. Rand, MD, Xiao-Xuan Wu, MD, Lucia R Wolgast, MD, Victor Lei, MSc, Edward M. Conway, MD PhD
Journal: Blood
Blood (2016) 128 (22): 719.
https://doi.org/10.1182/blood.V128.22.719.719
Published: 2016
Journal Articles

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor

Lakshmi C. Wijeyewickrema, Emilie Lameignere, Lilian Hor, Renee C. Duncan, Toshikazu Shiba, Richard J. Travers, Piyushkumar R. Kapopara, Victor Lei, Stephanie A. Smith, Hugh Kim, James H. Morrissey, Robert N. Pike, Edward M. Conway
Journal: Blood
Blood (2016) 128 (13): 1766–1776.
https://doi.org/10.1182/blood-2016-02-699561
Published: 2016
Includes: Supplemental data
Journal Articles

Sweeteners for factor H

Edward M. Conway
Journal: Blood
Blood (2016) 127 (22): 2656–2658.
https://doi.org/10.1182/blood-2016-04-708172
Published: 2016
Journal Articles

HUS and the case for complement

Edward M. Conway
Journal: Blood
Blood (2015) 126 (18): 2085–2090.
https://doi.org/10.1182/blood-2015-03-569277
Published: 2015
Journal Articles

Polyphosphate suppresses complement via the terminal pathway

Jovian M. Wat, Jonathan H. Foley, Michael J. Krisinger, Linnette Mae Ocariza, Victor Lei, Gregory A. Wasney, Emilie Lameignere, Natalie C. Strynadka, Stephanie A. Smith, James H. Morrissey, Edward M. Conway
Journal: Blood
Blood (2014) 123 (5): 768–776.
https://doi.org/10.1182/blood-2013-07-515726
Published: 2014
Includes: Supplemental data
Journal Articles

New specs for arteriovenous identity

Edward M. Conway
Journal: Blood
Blood (2013) 122 (24): 3857–3858.
https://doi.org/10.1182/blood-2013-10-533141
Published: 2013
Journal Articles

Gas6 gains entry into the coagulation cascade

Jonathan H. Foley, Edward M. Conway
Journal: Blood
Blood (2013) 121 (4): 570–571.
https://doi.org/10.1182/blood-2012-11-468678
Published: 2013
Journal Articles

Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway

Michael J. Krisinger, Verena Goebeler, Zhen Lu, Scott C. Meixner, Timothy Myles, Edward L. G. Pryzdial, Edward M. Conway
Journal: Blood
Blood (2012) 120 (8): 1717–1725.
https://doi.org/10.1182/blood-2012-02-412080
Published: 2012
Includes: Supplemental data
Journal Articles

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain

Netanel A. Horowitz, Elizabeth A. Blevins, Whitney M. Miller, Ashley R. Perry, Kathryn E. Talmage, Eric S. Mullins, Matthew J. Flick, Karla C. S. Queiroz, Kun Shi, C. Arnold Spek, Edward M. Conway, Brett P. Monia, Hartmut Weiler, Jay L. Degen, Joseph S. Palumbo
Journal: Blood
Blood (2011) 118 (10): 2889–2895.
https://doi.org/10.1182/blood-2011-03-341222
Published: 2011
Includes: Supplemental data
Journal Articles

Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia

Eugene Park, Eun Ji Gang, Yao-Te Hsieh, Paul Schaefer, Sanna Chae, Lars Klemm, Sandra Huantes, Mignon Loh, Edward M. Conway, Eun-Suk Kang, Hong Hoe Koo, Wolf-Karsten Hofmann, Nora Heisterkamp, Louis Pelus, Ganesan Keerthivasan, John Crispino, Michael Kahn, Markus Müschen, Yong-Mi Kim
Journal: Blood
Blood (2011) 118 (8): 2191–2199.
https://doi.org/10.1182/blood-2011-04-351239
Published: 2011
Includes: Supplemental data
Journal Articles

The Lectin-Like Domain of Thrombomodulin Protects Against Diabetic Nephropathy by Inhibiting Complement Activation

Hongjie Wang, Ilya Vinnikov, Qianxing Zhou, Thati Madhusudhan, Khurrum Shahzad, Muhammed Kashif, Juliane Wolter, Angelika Bierhaus, Peter Nawroth, Edward M. Conway, MD, PhD, FRCPC, MBA, Berend Isermann
Journal: Blood
Blood (2010) 116 (21): 654.
https://doi.org/10.1182/blood.V116.21.654.654
Published: 2010
Journal Articles

Survivin Modulates Gene Expression That Connects through An Extensive Functional Signaling Network and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1

Seiji Fukuda, MD, PhD, Pratibha Singh, PhD, Jonathan Hoggatt, PhD, Jennifer Speth, MS, Mariko Abe, MD, Edward M. Conway, MD, PhD, FRCPC, MBA, John Crispino, PhD, Giuseppina Nucifora, Seiji Yamaguchi, MD, Louis M. Pelus, PhD
Journal: Blood
Blood (2010) 116 (21): 87.
https://doi.org/10.1182/blood.V116.21.87.87
Published: 2010
Journal Articles

Targeting Survivin In Recalcitrant Acute Lymphoblastic Leukemia

Eugene Park, Enzi Jiang, MD, PhD, Yao-Te Hsieh, Lars Klemm, Cihangir Duy, Edward M. Conway, MD, PhD, FRCPC, MBA, Louis M. Pelus, PhD, John Crispino, PhD, Mignon L. Loh, M.D., Eun-Suk Kang, MD, PhD, Hong-Hoe Koo, MD, PhD, Allen Yang, MD, PhD, Nora Heisterkamp, PhD, Michael Kahn, PhD, Markus Muschen, MD, Yong-Mi Kim, MD, MPH
Journal: Blood
Blood (2010) 116 (21): 3263.
https://doi.org/10.1182/blood.V116.21.3263.3263
Published: 2010
Journal Articles

Regulation of Complement Activation by Thrombomodulin.

Mieke Delvaeye, PhD, Astrid DeVriese, Michael Moons, Naomi Esmon, PhD, Charles Esmon, PhD, Edward M. Conway, MD, PhD, FRCPC, FACP, MBA
Journal: Blood
Blood (2009) 114 (22): 5127.
https://doi.org/10.1182/blood.V114.22.5127.5127
Published: 2009
Journal Articles

Super factor B-gets atypical HUS

Edward M. Conway
Journal: Blood
Blood (2009) 114 (13): 2572–2574.
https://doi.org/10.1182/blood-2009-07-233643
Published: 2009
Journal Articles

Coagulation and innate immune responses: can we view them separately?

Mieke Delvaeye, Edward M. Conway
Journal: Blood
Blood (2009) 114 (12): 2367–2374.
https://doi.org/10.1182/blood-2009-05-199208
Published: 2009
Includes: Supplemental data