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Journal Articles

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL

Qi Han, Yan Gu, Huimin Xiang, Linyao Zhang, Yan Wang, Chan Yang, Jun Li, Chelsea Steiner, Rosa Lapalombella, Jennifer A. Woyach, Yiping Yang, Sinisa Dovat, Chunhua Song, Zheng Ge
Journal: Blood
Blood (2025) 145 (13): 1407–1421.
https://doi.org/10.1182/blood.2024024130
Published: 2025
Includes: Supplemental data
Journal Articles

Warthin-Finkeldey cells seen in a setting other than measles: chronic lymphocytic leukemia/small lymphocytic lymphoma

Tanner J. Bakhshi, Sergio Pina-Oviedo
Journal: Blood
Blood (2025) 145 (13): 1437.
https://doi.org/10.1182/blood.2024028017
Published: 2025
Journal Articles

NGS-based IG/TR rearrangement profiling in acute lymphoblastic leukemia: age dependence of immunogenetic maturation

Michaela Kotrova, Constantin Proske, Nikos Darzentas, Anna Laqua, Britta Kehden, Jan Christian Kässens, Sonja Bendig, Saskia Kohlscheen, Monika Szczepanowski, Wiebke Wessels, Željko Antić, Christiane Pott, Matthias Ritgen, Jacques J.M. van Dongen, Nicola Gökbuget, Guranda Chitadze, Anke Bergmann, Lorenz Bastian, Claudia D. Baldus, Gunnar Cario, Martin Schrappe, Stefan Schwartz, Julia Alten, Rolf Koehler, Monika Brüggemann
Journal: Blood
Blood blood.2024027175.
https://doi.org/10.1182/blood.2024027175
Published: 2025
Includes: Supplemental data
Journal Articles

Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragments covalently deposited on lymphoma cells

Sivasubramanian Baskar, Haiyong Peng, Erika M. Gaglione, Elizabeth J. Carstens, Margaret A. Lindorfer, Inhye E. Ahn, Sarah E. M. Herman, Martin Skarzynski, Jing Chang, Keyvan Keyvanfar, Vicent Butera, Amy Blackburn, Bérengère Vire, Irina Maric, Maryalice Stetler-Stevenson, Constance M. Yuan, Michael A. Eckhaus, Susan Soto, Mohammed Z. H. Farooqui, Ronald P. Taylor, Christoph Rader, Adrian Wiestner
Journal: Blood
Blood (2025) 145 (12): 1309–1320.
https://doi.org/10.1182/blood.2024024846
Published: 2025
Includes: Supplemental data
Journal Articles

MRD-guided zanubrutinib, venetoclax, and obinutuzumab in relapsed CLL: primary end point analysis from the CLL2-BZAG trial

CME Clinical Trials & Observations
Moritz Fürstenau, Sandra Robrecht, Christof Schneider, Eugen Tausch, Adam Giza, Matthias Ritgen, Jörg Bittenbring, Holger Hebart, Björn Schöttker, Anna Lena Illert, Ullrich Graeven, Andrea Stoltefuß, Bernhard Heinrich, Robert Eckert, Anna Fink, Janina Stumpf, Kirsten Fischer, Othman Al-Sawaf, Florian Simon, Fanni Kleinert, Jonathan Weiss, Karl-Anton Kreuzer, Anke Schilhabel, Monika Brüggemann, Petra Langerbeins, Stephan Stilgenbauer, Barbara Eichhorst, Michael Hallek, Paula Cramer
Journal: Blood
Blood (2025) 145 (12): 1282–1292.
https://doi.org/10.1182/blood.2024026685
Published: 2025
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis is clonally unrelated to multiple myeloma and is associated with specific microenvironmental changes

Marta Lionetti, Margherita Scopetti, Antonio Matera, Akihiro Maeda, Alessio Marella, Francesca Lazzaroni, Giancarlo Castellano, Sonia Fabris, Stefania Pioggia, Silvia Lonati, Alfredo Marchetti, Alessandra Cattaneo, Marta Tornese, Antonino Neri, Dr, Claudia Leoni, Loredana Pettine, Valentina Traini, Ilaria Silvestris, Marzia Barbieri, Giuseppina Fabbiano, Domenica Ronchetti, Elisa Taiana, Claudio De Magistris, Matteo Claudio Da Via', Francesco Passamonti, Niccolò Bolli
Journal: Blood
Blood blood.2024026236.
https://doi.org/10.1182/blood.2024026236
Published: 2025
Includes: Supplemental data
Journal Articles

NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma

Sojeong Kim, Jeong-Eun Kwak, June-Young Koh, Ji Eun Lee, Hye Won Kook, Minchae Kim, Haerim Chung, Yuri Kim, Soo Jeong Kim, Jin Seok Kim, June-Won Cheong, Min Goo Lee, Hoyoung Lee, Su-Hyung Park, Eui-Cheol Shin, Saeam Shin, Sun Och Yoon, Il-Kyu Choi, Jeong Seok Lee, Hyunsoo Cho
Journal: Blood
Blood blood.2024025875.
https://doi.org/10.1182/blood.2024025875
Published: 2025
Includes: Supplemental data
Journal Articles

Prognostic Biomarkers in MCL: Insights from the SHINE Trial on the impact of MCL35 score and TP53 Mutation Status

Ciara L Freeman, Srimathi Srinivasan, Brendan Hodkinson, Sanjay Deshpande, Todd Henninger, Merrill Boyle, Michael L Wang, Martin Dreyling, David W. Scott
Journal: Blood
Blood blood.2024026003.
https://doi.org/10.1182/blood.2024026003
Published: 2025
Includes: Supplemental data
Journal Articles

STAT1-mediated interferon signatures associate with preclinical JAK-inhibitor sensitivity in T-cell acute lymphoblastic leukemia

Jason Xu, Jonathan H Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney L Vincent, Shovik Bandyopadhyay, Elizabeth Y Li, Tristan Lee Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L Wald, Gregory M Chen, David Wei Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Maria Bernt, Brent L. Wood, Stuart Sheldon Winter, Kimberly P. Dunsmore, Elizabeth A. Raetz, Meenakshi Devidas, Stanley B Pounds, Mignon L. Loh, Stephen P Hunger, Mark Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J Yang, Kai Tan, David Trent Teachey
Journal: Blood
Blood blood.2025028566.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

Biology as vulnerability in follicular lymphoma: genetics, epigenetics, and immunogenetics

Ferran Araujo-Ayala, Wendy Béguelin
Journal: Blood
Blood blood.2024026020.
https://doi.org/10.1182/blood.2024026020
Published: 2025
Journal Articles

Lymphoid Malignancies in patients with Shwachman-Diamond Syndrome

Helen D. Reed, Hyunwoo Do, Edie A. Weller, Marian H. Harris, Christopher R. Reilly, Harrison K. Tsai, Jason E. Farrar, Bonnie W. Lau, Lauren Pommert, Christopher J. Gamper, Ian Atkinson, Katherine Coyne, Margret Joos, Sara Katherine Loveless, Sarah K. Steltz, Leah Cheng, Maggie Malsch, Kasiani C. Myers, Akiko Shimamura
Journal: Blood
Blood blood.2024026507.
https://doi.org/10.1182/blood.2024026507
Published: 2025
Journal Articles

Loss of BCL7A Permits IRF4 Transcriptional Activity and Cellular Growth in Multiple Myeloma

Chandraditya Chakraborty, Srikanth Talluri, Moritz Binder, Eugenio Morelli, Jessica Encinas Mayoral, Sanika Derebail, Anil Aktas Samur, Charles B. Epstein, Kenneth C. Anderson, Masood A Shammas, Mehmet K. Samur, Mariateresa Fulciniti, Nikhil C. Munshi
Journal: Blood
Blood blood.2024026588.
https://doi.org/10.1182/blood.2024026588
Published: 2025
Includes: Supplemental data
Journal Articles

Genetic and epigenetic mechanisms of GPRC5D loss after anti-GPRC5D CAR T-cell therapy in multiple myeloma

Sha Ma, Jieyun Xia, Miao Zhang, Wenyu Li, Meng Xiao, Yuqian Sha, Wenya Wang, Jianteng Zhou, Ying Wang, Kunming Qi, Chunling Fu, Zengtian Sun, Dian Zhou, Qian Sun, Tingting Qiu, Zhiling Yan, Feng Zhu, Wei Chen, Hai Cheng, Wei Sang, Jiang Cao, Depeng Li, Zhenyu Zhen Li, Mariateresa Fulciniti, Yao Yao, Kailin Xu, Mingshan Niu
Journal: Blood
Blood blood.2024026622.
https://doi.org/10.1182/blood.2024026622
Published: 2025
Includes: Supplemental data
Journal Articles

Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

Haopeng Yang, Wenchao Zhang, Vida Ravanmehr, Guiling Cui, Kevin Bowman, Ruidong Chen, Jared Henderson, Shyanne Ruby Lockman, Estela Rojas, Ashley Lauren Wilson, Sydney Parsons, Ariel Mechaly, Leslie Regad, Ahmed Haouz, Christopher R. Flowers, Sattva S. Neelapu, Loretta J. Nastoupil, Richard Eric Davis, Qing Deng, Fernando Rodrigues Lima, Michael R Green
Journal: Blood
Blood blood.2024026664.
https://doi.org/10.1182/blood.2024026664
Published: 2025
Includes: Supplemental data
Journal Articles

Development of ALL-Hematotox: predicting post-CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Monica S. Nair, Sara K. Silbert, Kai Rejeski, Karilynn A. Wilson, Adam J. Lamble, Yannis Valtis, Bonnie Yates, Alexa Morales Arana, Roni Shouval, Kevin Curran, Rebecca A. Gardner, Haneen Shalabi, Colleen Annesley, Jae H. Park, Marion Subklewe, Nirali N. Shah
Journal: Blood
Blood (2025) 145 (11): 1136–1148.
https://doi.org/10.1182/blood.2024025910
Published: 2025
Includes: Supplemental data
Journal Articles

The ADAR1-regulated cytoplasmic dsRNA-sensing pathway is a novel mechanism of lenalidomide resistance in multiple myeloma

Mun Yee Koh, Tae-Hoon Chung, Nicole Xin Ning Tang, Sabrina Hui Min Toh, Jianbiao Zhou, Tze King Tan, Leilei Chen, Wee Joo Chng, Phaik Ju Teoh
Journal: Blood
Blood (2025) 145 (11): 1164–1181.
https://doi.org/10.1182/blood.2024024429
Published: 2025
Includes: Supplemental data
Journal Articles

DNTT-mediated DNA damage response drives inotuzumab ozogamicin resistance in B-cell acute lymphoblastic leukemia

Carolin S. Escherich, Takaya Moriyama, Zhenhua Li, Yu-Chih Hsiao, Wenjian Yang, Yizhen Li, Noemi Reyes, Megan Walker, Amit Budhraja, Sheetal Bhatara, Ernesto Diaz-Flores, Wendy Stock, Elisabeth Paietta, Marina Y. Konopleva, Steven M. Kornblau, Mark R. Litzow, Hiroto Inaba, Ching-Hon Pui, Joseph T. Opferman, Mignon L. Loh, Jiyang Yu, Maureen M. O’Brien, William E. Evans, Jun J. Yang
Journal: Blood
Blood (2025) 145 (11): 1182–1194.
https://doi.org/10.1182/blood.2024026085
Published: 2025
Includes: Supplemental data
Journal Articles

Heat-insoluble cryoglobulin in peripheral blood

Keyliz Peraza Cruces, Katalin Marianna Kovacs
Journal: Blood
Blood (2025) 145 (11): 1225.
https://doi.org/10.1182/blood.2024027775
Published: 2025
Journal Articles

Targeting senescent stemlike subpopulations in Philadelphia chromosome–like acute lymphoblastic leukemia

Yang-Yang Ding, Jonathan H. Sussman, Kellyn Madden, Joseph P. Loftus, Robert K. Chen, Catherine D. Falkenstein, Diego A. Bárcenas López, David A. Hottman, Benjamin Mathier, Wenbao Yu, Jason Xu, Changya Chen, Chia-Hui Chen, Bing He, Shovik Bandyopadhyay, Zhan Zhang, DongGeun Lee, Hong Wang, Junmin Peng, Chi V. Dang, Kai Tan, Sarah K. Tasian
Journal: Blood
Blood (2025) 145 (11): 1195–1210.
https://doi.org/10.1182/blood.2024026482
Published: 2025
Includes: Supplemental data
Journal Articles

Large-scale dependency and drug screens characterize the therapeutic vulnerabilities of Multiple Myeloma with 1q+

Romanos Sklavenitis-Pistofidis, Elizabeth D Lightbody, Mairead Reidy, Junko Tsuji, Jean-Baptiste Alberge, Michelle P Aranha, Daniel Lewis Heilpern-Mallory, Harvey G. Roweth, Daisy Huyng, Stephen Jun Fei Chong, Anna Y. Chung, Jeremy Zhang, Liam Hackett, Nicholas J Haradhvala, Ting Wu, Nang Kham Su, Brianna Berrios, Saveliy Belkin, Ankit K. Dutta, Ryan A Knudson, Carolyn Brandt, Patricia T. Greipp, Matthew S. Davids, Maria Papaioannou, Gad Getz, Irene M Ghobrial, Salomon Manier
Journal: Blood
Blood blood.2024025102.
https://doi.org/10.1182/blood.2024025102
Published: 2025
Includes: Supplemental data