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Journal Articles

Remission conversion drives outcomes after CAR T-cell therapy for multiple myeloma: a registry analysis from the DRST

Available to Purchase
Clinical Trials & Observations
Maximilian Merz, Nico Gagelmann, Samih Smaili, Sarah Flossdorf, Sandra Sauer, Christof Scheid, Bastian von Tresckow, Gerald Wulf, Katja Weisel, Igor Wolfgang Blau, Monika Engelhardt, Ralph Wäsch, Natalie Schub, Raphael Teipel, Judith Hecker, Johannes Waldschmidt, Britta Besemer, Ben-Niklas Baermann, Simon Call, Leo Hansmann, Francis Ayuketang Ayuk, Marc S. Raab, Hermann Einsele, Uwe Platzbecker, Nicolaus Kröger
Journal: Blood
Blood (2025) 146 (14): 1677–1686.
https://doi.org/10.1182/blood.2025028330
Published: 2025
Includes: Supplemental data
Journal Articles

Matched donor allogeneic CAR-T for adult B-ALL: toxicity, efficacy, repeat dosing, and the importance of lymphodepletion

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Clinical Trials & Observations
Claire Roddie, Juliana Dias, Maeve A. O’Reilly, Mahnaz Abbasian, Amaia Cadinanos-Garai, Ketki Vispute, Leticia Bosshard-Carter, Marina Mitsikakou, Eftychia Charalambous, Vedika Mehra, Harriet Roddy, Gordon Weng-Kit Cheung, John A. Hartley, Nasir Mahmoud, Leah Ensell, Yashma Patel, Maria A. V. Marzolini, Farzin Farzaneh, Lauren Nickolay, Nourredine Himoudi, Farhatullah Syed, Bilyana Popova, Sevasti Galani, Alexander Day, Mark W. Lowdell, Karl S. Peggs
Journal: Blood
Blood (2025) 146 (14): 1664–1676.
https://doi.org/10.1182/blood.2025028790
Published: 2025
Includes: Supplemental data
Journal Articles

A new prognostic index (CLIPI) for advanced cutaneous lymphoma enables precise patient risk stratification

Available to Purchase
Clinical Trials & Observations Brief Report
Julia J. Scarisbrick, Pietro Quaglino, Sean Whittaker, Martine Bagot, Emmanuella Guenova, Evangelia Papadavid, Henry Miles Prince, Jose A. Sanches, Denis R. Miyashiro, Octavio Servitje, Christiane Querfeld, Oleg Akilov, Arvind Arumainathan, Luke Bennett, Maxime Battistella, Kim Benstead, Emilio Berti, Marie Beylot-Barry, Anne-Marie Busschots, Richard Cowan, Reinhard Dummer, Giles Dunnill, Teresa Estrach, Felicity Evison, Abraham Bashir, Larisa Geskin, Ale Gru, Joan Guitart, Melba C. Herrera, Emillia Hodak, Steve Horwitz, Constanze Jonak, Claus-Detlev Klemke, Robert Knobler, Pam Mckay, Marta Marschalkó, Cesare Massone, Rubeta Matin, Christina Mitteldorf, Robert Novoa, Pablo Ortiz-Romero, Nicola Pimpinelli, Ramon M. Pujol, Annmari Ranki, Liisa Vakeva, Kerri E. Rieger, Rudolf Stadler, Franz Trautinger, Johanna Latzka, Maarten Vermeer, Rachel Wachsmuth, Sophie Weatherhead, Ulrike Wehkamp, Marion Wobser, Youn H. Kim
Journal: Blood
Blood (2025) 146 (14): 1687–1692.
https://doi.org/10.1182/blood.2025029628
Published: 2025
Includes: Supplemental data
Journal Articles

The Biology of MZL subtypes: Challenge and Relevance of Classification

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Camille Laurent, Francesco Bertoni
Journal: Blood
Blood blood.2024028268.
https://doi.org/10.1182/blood.2024028268
Published: 2025
Includes: Supplemental data
Journal Articles

PROs vs clinician-reported adverse events in a large clinical trial: findings from the phase 3 POLARIX study

Open Access
Carrie Thompson, Marek Trněný, Franck Morschhauser, Gilles A. Salles, Patrick M. M. Reagan, Mark Hertzberg, Huilai Zhang, Catherine Thieblemont, Bei Hu, Gustavo Fonseca, Won Seog Seog Kim, Maurizio Martelli, Amitkumar Mehta, Avrita Singh, Mark Yan, Jamie Hirata, Matthew Sugidono, Calvin Lee, MD, Jeff P. Sharman, Neha Mehta-Shah, Christopher R. Flowers, Hervé Tilly, Neil Chua, Olivier Casasnovas, Fiona Miall, Tae Min Min Kim, Xavier Cheng-Hong Tsai, Sunita D. Nasta, Seung Tae Lee, Jonathan W. Friedberg
Journal: Blood
Blood blood.2025028848.
https://doi.org/10.1182/blood.2025028848
Published: 2025
Journal Articles

Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma

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Benjamin Diamond, Linda Baughn, Mansour Poorebrahim, Alexandra M. Poos, Holly Lee, Marcella Kaddoura, J. Erin Wiedmeier-Nutor, Michael Durante, Gregory Otteson, Dragan Jevremovic, Hongwei Tang, Stefan Fröhling, Marc A. Baertsch, Marios Papadimitriou, Bachisio Ziccheddu, Tomas Jelinek, Cendrine Lemoine, Alexey Rak, Damian J. Green, Ola Landgren, Paola Neri, Leif Bergsagel, Esteban Braggio, Shaji Kumar, Marc S. Raab, Rafael Fonseca, Nizar Bahlis, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2025) 146 (13): 1575–1585.
https://doi.org/10.1182/blood.2024028107
Published: 2025
Includes: Supplemental data
Journal Articles

Genomic landscape of IgM-MGUS and patients with stable or progressive asymptomatic Waldenström macroglobulinemia

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Tina Bagratuni, Dr, Ourania Theologi, Christos Vlachos, Dr, Ioannis Kollias, Kylee H. Maclachlan, Foteini Aktypi, Nefeli Mavrianou-Koutsoukou, Christine I Liacos, Konstantina Taouxi, Alexandra Papadimou, Katerina Chrisostomidou, Maria Sakkou, Irene Solia, Foteini Theodorakou, Gianmarco Favrin, Maria Gavriatopoulou, Evangelos Terpos, Marzia Varettoni, Zachary R Hunter, Steven P. Treon, Francesco Maura, Meletios-Athanasios Athanasios Dimopoulos, Efstathios Kastritis
Journal: Blood
Blood blood.2025030177.
https://doi.org/10.1182/blood.2025030177
Published: 2025
Includes: Supplemental data
Journal Articles

Somatic IRF4 mutations and thymic tropism in primary mediastinal large B-cell lymphoma

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Shinya Rai, Gerben Duns, Fabian Frontzek, Jasper C. H. Wong, Yifan Yin, Michael Yu Li, Makoto Kishida, Manabu Fujisawa, Shannon Healy, Elena Viganò, Aixiang Jiang, Bruce Woolcock, Adèle Telenius, Susana Ben-Neriah, Barbara Meissner, Merrill Boyle, Hisae Nakamura, Luke O’Brien, Claudia Cassidy, Andrew Lytle, Pedro Farinha, Graham Slack, Laura K. Hilton, Ryan D. Morin, Leandro Venturutti, Tomohiro Aoki, Nicole Wretham, Jonathan W. Bush, Laura Evgin, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2025) 146 (13): 1586–1600.
https://doi.org/10.1182/blood.2025028412
Published: 2025
Includes: Supplemental data
Journal Articles

Association of Epstein-Barr virus genomic alterations with human pathologies

Open Access
Htet Thiri Khine, Yoshitaka Sato, Motoharu Hamada, Miki Umeda, Akira Iizuka, Shika Son, Haruto Arai, Yuki Kojima, Takahiro Watanabe, Azumi Naruse, Kimitoshi Goto, Koichi Ohshima, Yuta Akutsu, Masato Nakaguro, Akira Satou, Hiromi Kataoka, Yoshinori Ito, Akihisa Sawada, Seiichi Kato, Jun-ichi Kawada, Takayuki Murata, Yusuke Okuno, Hiroshi Kimura
Journal: Blood
Blood (2025) 146 (13): 1533–1545.
https://doi.org/10.1182/blood.2024028055
Published: 2025
Includes: Supplemental data
Journal Articles

Deciphering the dynamics of histone acetylation and chromatin remodeling in multiple myeloma: a tale beyond the tails

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Sinan Xiong, Jianbiao Zhou, Wee-Joo Chng
Journal: Blood
Blood (2025) 146 (13): 1550–1560.
https://doi.org/10.1182/blood.2025028403
Published: 2025
Includes: Supplemental data
Journal Articles

High-risk genomic consensus validation for patients with newly diagnosed multiple myeloma using next-generation sequencing

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Anaïs Schavgoulidze, Aurore Perrot, Xavier Leleu, Titouan Cazaubiel, Marie-Lorraine Chretien, Pierre Feugier, Karim Belhadj, Salomon Manier, Murielle Roussel, Sabine Brechignac, Frederique Orsini Piocelle, Mohamad Mohty, Jean Marc Schiano de Colella, Margaret Macro, Dr, Didier Adiko, Mamoun Dib, Jean Fontan, Carine Motard, Didier Bouscary, Laurent Pascal, Virginie Roland, Francois Lifermann, Jana Armelle Bakala, Lydia Montes, Celine Kennel, Philippe Rey, Valentine Richez, Faiza Keddar, Laurent Frenzel, Claire Calmettes, Carine Chaleteix, Isabelle Plantier, Emilie Chalayer, Anna Schmitt, Christophe Roul, Hélène Demarquette, Chloe Cerutti, Luka Pavageau, Laure Derrier, Hervé Avet-Loiseau, Jill Corre
Journal: Blood
Blood blood.2025029999.
https://doi.org/10.1182/blood.2025029999
Published: 2025
Includes: Supplemental data
Journal Articles

INCREASED LEF1 PROTEIN LEVELS AND ISOFORM SWITCHING DRIVE CELL PROLIFERATION IN CHRONIC LYMPHOCYTIC LEUKEMIA

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Judith Mateos-Jaimez, Anna Vidal Crespo, Stella Charalampopoulou, Raul Fernandez Perez, Vicente Chapaprieta, Víctor Jiménez-Martínez, Liska Caviedes-Cárdenas, Martí Duran-Ferrer, Guadalupe Espadas, Eduard Sabido, Anne Largeot, Sophie A. Herbst, Sascha Dietrich, Miguel Bastos Boente, Miguel Alcoceba, Ferran Nadeu, Ingo Ringshausen, Jerome Paggetti, Etienne Moussay, Dolors Colomer, Elías Campo, Alba Maiques-Diaz, Jose Ignacio Martin-Subero
Journal: Blood
Blood blood.2025030129.
https://doi.org/10.1182/blood.2025030129
Published: 2025
Includes: Supplemental data
Journal Articles

A phase 2 trial of CHOP with anti-CCR4 antibody mogamulizumab for older patients with adult T-cell leukemia/lymphoma

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Clinical Trials & Observations
Makoto Yoshimitsu, Ilseung Choi, Shigeru Kusumoto, Mototsugu Shimokawa, Atae Utsunomiya, Youko Suehiro, Tomonori Hidaka, Kisato Nosaka, Hidenori Sasaki, Shinya Rai, Shinobu Tamura, Satsuki Owatari, Ki-Ryang Koh, Daisuke Nakamura, Masahito Tokunaga, Masaaki Sekine, Yuma Sakamoto, Hiroshi Inagaki, Takashi Ishida, Kenji Ishitsuka
Journal: Blood
Blood (2025) 146 (12): 1440–1449.
https://doi.org/10.1182/blood.2024027902
Published: 2025
Includes: Supplemental data
Journal Articles

Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment

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Nicolas A. Gort-Freitas, Maria Moscvin, Matteo C. Da Vià, Francesca Lazzaroni, Alice Nevone, Sam Sadigh, Samuel Boullt, Benjamin Evans, Tianzeng Chen, Tanya Karagiannis, Albert Tai, Sean Rowell, Srinidhi Raghav, Antonia F. Chen, Jacob P. Laubach, Caitlin Edwards, Jon C. Aster, Zizhang Sheng, Joao A. Paulo, Chi N. Chan, Mario Nuvolone, Niccolò Bolli, Raymond L. Comenzo, Allon M. Klein, Giada Bianchi
Journal: Blood
Blood (2025) 146 (12): 1476–1492.
https://doi.org/10.1182/blood.2024024719
Published: 2025
Includes: Supplemental data
Journal Articles

Drug development in MZL: caring for the forgotten child

Open Access
Catherine Thieblemont, Sylvain Carras, Côme Bommier
Journal: Blood
Blood blood.2024028270.
https://doi.org/10.1182/blood.2024028270
Published: 2025
Journal Articles

The mitochondrial protease ClpP is a metabolic vulnerability and an immunogenic trigger against multiple myeloma

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Tommaso Perini, Paola Zordan, Rossella Del Pizzo, Massimo Resnati, Lisa Viviani, Davide Stefanoni, Laura Cassina, Ugo Orfanelli, Matteo Trudu, Laura Oliva, Daniel Lacidogna, Mehmet K. Samur, Maria Materozzi, Denise Drago, Annapaola Andolfo, Marco Patrone, Massimo Degano, Alessandra Boletta, Enrico Milan, Fabio Ciceri, Nikhil C. Munshi, Matteo Bellone, Simone Cenci
Journal: Blood
Blood (2025) 146 (11): 1286–1299.
https://doi.org/10.1182/blood.2024026340
Published: 2025
Includes: Supplemental data
Journal Articles

Large B-cell lymphoma imprints a dysfunctional immune phenotype that persists years after treatment

Open Access
Richard J. Pelzl, Giulia Benintende, Franziska Gsottberger, Julia K. Scholz, Matthias Ruebner, Hao Yao, Kerstin Wendland, Kai Rejeski, Heidi Altmann, Srdjan Petkovic, Lisa Mellenthin, Sabrina Kübel, Moritz Schmiedeberg, Paulina Klein, Agnese Petrera, Rebecca Baur, Sophie Eckstein, Sandra Hoepffner-Grundy, Christoph Röllig, Marion Subklewe, Hanna Huebner, Georg Schett, Andreas Mackensen, Luca Laurenti, Frederik Graw, Simon Völkl, Krystelle Nganou-Makamdop, Fabian Müller
Journal: Blood
Blood (2025) 146 (11): 1300–1313.
https://doi.org/10.1182/blood.2024027877
Published: 2025
Includes: Supplemental data
Journal Articles

Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer

Open Access
Bernd B. Zeisig, Chiou-Tsun Tsai, Clemence Virely, Tsz Kan Fung, Ali Tuğrul Akin, Estelle Troadec, Bo Jiao, I. Richard Thompson, Priscilla Nga Ieng Lau, Nanjun Li, Andriani Charalambous, Larissa Bomfim, Jennifer Lynch, Athina Georgiou, Robbert Hoogeboom, Claire Lynn, Si-Yi Zhang, Piers E. M. Patten, Cynthia L. Fisher, Anna Schuh, Seishi Ogawa, Ghulam Mufti, Mohammad M. Karimi, Chi Wai Eric So
Journal: Blood
Blood (2025) 146 (11): 1314–1330.
https://doi.org/10.1182/blood.2025028560
Published: 2025
Includes: Supplemental data
Journal Articles

Acalabrutinib-obinutuzumab improves survival vs chemoimmunotherapy in treatment-naive CLL in the 6-year follow-up of ELEVATE-TN

Open Access
Clinical Trials & Observations
Jeff P. Sharman, Miklos Egyed, Wojciech Jurczak, Alan Skarbnik, Krish Patel, Ian W. Flinn, Manali Kamdar, Talha Munir, Renata Walewska, Marie Hughes, Laura Maria Fogliatto, Yair Herishanu, Versha Banerji, George Follows, Patricia Walker, Paolo Ghia, Ann Janssens, John C. Byrd, Emmanuelle Ferrant, Alessandra Ferrajoli, William G. Wierda, Catherine Wangui Wachira, Batul T. Suterwala, Paulo Miranda, Veerendra Munugalavadla, Chuan-Chuan Wun, Jennifer A. Woyach
Journal: Blood
Blood (2025) 146 (11): 1276–1285.
https://doi.org/10.1182/blood.2024024476
Published: 2025
Includes: Supplemental data
Journal Articles

Nuclear respiratory factor 1 promotes cell survival in multiple myeloma under proteasome inhibition therapy

Open Access
Tiziana Bruno, Maria Chiara Cappelletto, Clelia Cortile, Stefano Di Giovenale, Bruno Amadio, Francesca De Nicola, Italia Falcone, Stefano Giuliani, Belinda Palermo, Valeria Catena, Ludovica Ciuffreda, Fulvia Cerruti, Paolo Cascio, Roberta Merola, Serena Masi, Valentina De Pascale, Ombretta Annibali, Silvia Ferraro, +39, Svitlana Gumenyuk, Francesco Pisani, Francesco Marchesi, Andrea Mengarelli, Maurizio Fanciulli, Giacomo Corleone
Journal: Blood
Blood blood.2025028441.
https://doi.org/10.1182/blood.2025028441
Published: 2025
Includes: Supplemental data