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Journal Articles

Unrelated donor selection with PTCy

Johannes Schetelig, Martin Bornhäuser
Journal: Blood
Blood (2024) 143 (24): 2450–2451.
https://doi.org/10.1182/blood.2024024551
Published: 2024
Journal Articles

Graft-Versus-Host Disease after Anti-CD19 Chimeric Antigen Receptor T-Cell Infusion Post Allogeneic Hematopoietic Cell Transplantation: A Transplant Complications and Paediatric Disease Working Parties EBMT Joint Study

Guillermo Orti, Christophe Peczynski, Christian Koenecke, William Boreland, Maeve O'Reilly, Martin Bornhäuser, Adriana Balduzzi, Caroline Besley, Krzysztof Kalwak, Samppa Ryhanen, Sr., Tayfun Güngör, Robert F. Wynn, Peter Bader, Stephan Mielke, Didier Blaise, Persis Amrolia, Ibrahim Yakoub-Agha, Friso G. J. Calkoen, Maria-Luisa Schubert, Victoria Potter, Wolfgang Holter, Nicolaus Kröger, Mi Kwon, Henrik Sengeloev, Helene Schoemans, Ivan Sergeevich Moiseev, Olaf Penack, Zinaida Peric
Journal: Blood
Blood (2023) 142 (Supplement 1): 2189.
https://doi.org/10.1182/blood-2023-177715
Published: 2023
Journal Articles

Impact of KMT2A -PTD Mutational Subgroups on Outcome of AML Patients after Induction Therapy and Allogeneic Hematopoietic Cell Transplantation

Desiree Kunadt, Sven Zukunft, Klaus H Metzeler, Christoph Röllig, Christoph Schliemann, Jan Braess, Carsten Müller-Tidow, Alwin Kraemer, Sebastian Scholl, Inken Hilgendorf, Edgar Jost, Björn Steffen, Gesine Bug, Hermann Einsele, Kerstin Schäfer-Eckart, Stefan W. Krause, Mathias Hänel, Thomas Schroeder, Martin Kaufmann, Jan Moritz Middeke, Katja Sockel, Leo Ruhnke, Uwe Platzbecker, Hubert Serve, Matthias Stelljes, Claudia D Baldus, Andreas Neubauer, Johannes Schetelig, David Poitz, Christian Thiede, Martin Bornhäuser, Friedrich Stölzel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2236.
https://doi.org/10.1182/blood-2023-187273
Published: 2023
Journal Articles

Treosulfan-Based Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation (alloHSCT) for Patients with Myelodysplastic Syndrome (MDS): Comparative Analysis of a Randomized Controlled Trial and Real-World Data

Matthias Stelljes, Katja Sockel, Matthias Floeth, Johannes Schetelig, Martin Bornhäuser, Christian Reicherts, Georg Lenz, Thomas Schröder, Rudolf Trenschel, Miroslaw Markiewicz, Hélène Labussière-Wallet, Péter Reményi, Fabio Ciceri, Friedrich Stölzel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3526.
https://doi.org/10.1182/blood-2023-180816
Published: 2023
Journal Articles

Unrelated Donors below 35 Years of Age Should be Preferred over HLA-Matched Sibling Donors Older Than 50 Years for Patients with Myeloid Malignancies

Johannes Schetelig, Henning Baldauf, Carina Rave, Gesine Bug, Lutz Peter Hermann Mueller, Eva Wagner Drouet, Francis A. Ayuk, Wolfgang Andreas Bethge, Matthias Stelljes, Thomas Schröder, Desiree Kunadt, Katja Sockel, Jan Moritz Middeke, Daniel Fürst, Alexander H. Schmidt, Katharina Fleischhauer, Martin Bornhäuser
Journal: Blood
Blood (2023) 142 (Supplement 1): 1046.
https://doi.org/10.1182/blood-2023-180531
Published: 2023
Journal Articles

Secondary-Type Mutations Do Not Impact the Favorable Outcome of NPM1 -Mutated Acute Myeloid Leukemia Patients - Results from a Large Cohort of Intensively Treated Patients

Marius Bill, Jan-Niklas Eckardt, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Utz Krug, Bernhard Wörmann, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Hermann Einsele, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hanel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Leo Ruhnke, Johannes Schetelig, Jan Moritz Middeke, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Müller-Tidow, Martin Bornhäuser, Tobias Herold, Christian Thiede, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 721.
https://doi.org/10.1182/blood-2023-186160
Published: 2023
Journal Articles

Explainable End-to-End Supervised Learning Identifies Myelodysplastic Neoplasms in Bone Marrow Smears

Jan-Niklas Eckardt, Tim Schmittmann, Freya Schulze, Sebastian Riechert, Martin M. K. Schneider, Lukas Reichel, Miriam Eva Helena Gediga, Katja Sockel, Anas Shekh Sulaiman, Ekaterina Balaian, Christoph Röllig, Frank P. Kroschinsky, Anne Marie Asemissen, Uwe Platzbecker, Christian Pohlkamp, Torsten Haferlach, Karsten Wendt, Martin Bornhäuser, Jan Moritz Middeke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2269.
https://doi.org/10.1182/blood-2023-185628
Published: 2023
Journal Articles

Mimicking Clinical Trials with Synthetic Acute Myeloid Leukemia Patients Using Generative Artificial Intelligence

Jan-Niklas Eckardt, Waldemar Hahn, Christoph Röllig, Sebastian Stasik, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Christian Thiede, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Jan Moritz Middeke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2268.
https://doi.org/10.1182/blood-2023-179817
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Common in Unrelated Stem Cell Donors but Has No Impact on Patient Outcome after Hematopoietic Stem Cell Transplantation

Johannes Schetelig, Frederik Damm, Ulf - Peter Günther, Henning Baldauf, Carina Rave, Linda Koster, Gerhard Schöfl, Anja Klussmeier, Kamal Menghrajani, Kelly L. Bolton, Elke Rücker-Braun, Falk Heidenreich, Marie Münn, Markus Fuhrmann, Ilaria Visco, Mareike Frick, Raphael Hablesreiter, Christopher Maximilian Arends, Liesbeth C. de Wreede, Olena Nesterenko, Matthias Stelljes, Gesine Bug, Thomas Schröder, Ivan Sergeevich Moiseev, Helene Schoemans, Christian Koenecke, Raphael Teipel, Malte von Bonin, Lars Bullinger, Martin Bornhäuser, Marcel R.M. van den Brink, Alexander H. Schmidt, Vinzenz Lange, Zinaida Peric, Olaf Penack
Journal: Blood
Blood (2023) 142 (Supplement 1): 942.
https://doi.org/10.1182/blood-2023-179112
Published: 2023
Journal Articles

Cryopreservation Changes the Immune Effector Cell Composition of Peripheral Blood Stem Cell Grafts: An Analysis from the DKMS and NMDP Graft Composition Study

Elke Rücker-Braun, Bose Falk, Kate A. Markey, Hans Minderman, Henning Baldauf, Nicole Heymann, Heike Uhlemann, Lisa Heiduschke, Hugh R. MacMillan, Evan W. Newell, Kieran L. O'Loughlin, Ashley Spahn, Orla Maguire, Deborah Buk, Martin Bornhäuser, Alexander H. Schmidt, Steven M. Devine, Johannes Schetelig, Jeffery J. Auletta, Marcel R.M. van den Brink, Stephen R. Spellman, Falk Heidenreich
Journal: Blood
Blood (2023) 142 (Supplement 1): 1036.
https://doi.org/10.1182/blood-2023-179140
Published: 2023
Journal Articles

Risk Stratification of Patients with RUNX1- mutated Acute Myeloid Leukemia

Christian Rausch, Roman Hornung, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Vindi Jurinovic, Bianka Ksienzyk, Stephanie Schneider, Annika Maria Dufour, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Jan Braess, Wolfgang Hiddemann, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Johannes Schetelig, Moritz Middeke, Sebastian Stasik, Katharina Egger-Heidrich, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia D Baldus, Carsten Müller-Tidow, Uwe Platzbecker, Hubert Serve, Wendy Stock, Geoffrey L Uy, John C. Byrd, Deedra Nicolet, Ann-Kathrin Eisfeld, Ulrich Mansmann, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2023-174059
Published: 2023
Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone (HAM-Ven) As Salvage Treatment for Relapsed/Refractory AML: Updated Results of the Phase-I/II SAL Relax Trial

Leo Ruhnke, Christoph Schliemann, Jan-Henrik Mikesch, Matthias Stelljes, Lars Fransecky, Björn Steffen, Martin Kaufmann, Andreas Burchert, Andreas Rank, Maher Hanoun, Alexander Höllein, Sabrina Kraus, Mathias Hänel, Kerstin Schäfer-Eckart, Annett Haake, Frank Fiebig, Sven Zukunft, Jan Moritz Middeke, Désirée Kunadt, Johannes Schetelig, Malte von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Friedrich Stölzel, Claudia D Baldus, Hubert Serve, Martin Wermke, Martin Bornhäuser, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 160.
https://doi.org/10.1182/blood-2023-184445
Published: 2023
Journal Articles

Spatially Resolved Transcriptomics Unveils Unique T-Cell Dysfunctional States and Prognostic Gene Expression Signatures in TP53 -Mutated Acute Myeloid Leukemia

Jayakumar Vadakekolathu, Heidi Altmann, Manja Wobus, Malte von Bonin, Marc Schmitz, Gustavo B. Baretton, Robert Zeiser, Martin Bornhäuser, Sergio Rutella
Journal: Blood
Blood (2023) 142 (Supplement 1): 291.
https://doi.org/10.1182/blood-2023-174871
Published: 2023
Journal Articles

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Manja Meggendorfer, Enrico Tiacci, Christian Thiede, Richard Schlenk, Richard Dillon, Sebastian Stasik, Alessandra Venanzi, Sarah Bertoli, Eric Delabesse, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Amanda F. Gilkes, Ian Thomas, Maria Teresa Voso, Alessandro Rambaldi, Lorenzo Brunetti, Vincenzo M. Perriello, Vibeke Andresen, Bjorn T. Gjertsen, Maria Paola Martelli, Christian Récher, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Carsten Müller-Tidow, Claudia D. Baldus, Tortsten Haferlach, Nigel Russell, Brunangelo Falini
Journal: Blood
Blood (2023) 141 (15): 1846–1857.
https://doi.org/10.1182/blood.2022018108
Published: 2023
Includes: Supplemental data
Journal Articles

T cells reloaded after allogeneic HCT

Martin Bornhäuser
Journal: Blood
Blood (2023) 141 (14): 1652–1653.
https://doi.org/10.1182/blood.2022019106
Published: 2023
Journal Articles

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Maike Janssen, Christina Schmidt, Peter-Martin Bruch, Maximilian F. Blank, Christian Rohde, Alexander Waclawiczek, Daniel Heid, Simon Renders, Stefanie Göllner, Lisa Vierbaum, Birgit Besenbeck, Sophie A. Herbst, Mareike Knoll, Carolin Kolb, Adriana Przybylla, Katharina Weidenauer, Anne Kathrin Ludwig, Margarete Fabre, Muxin Gu, Richard F. Schlenk, Friedrich Stölzel, Martin Bornhäuser, Christoph Röllig, Uwe Platzbecker, Claudia Baldus, Hubert Serve, Tim Sauer, Simon Raffel, Caroline Pabst, George Vassiliou, Binje Vick, Irmela Jeremias, Andreas Trumpp, Jeroen Krijgsveld, Carsten Müller-Tidow, Sascha Dietrich
Journal: Blood
Blood (2022) 140 (24): 2594–2610.
https://doi.org/10.1182/blood.2021014241
Published: 2022
Includes: Supplemental data
Journal Articles

In Patients with Relapsed/Refractory AML Sequential Conditioning and Immediate Allogeneic Stem Cell Transplantation (allo-HCT) Results in Similar Overall and Leukemia-Free Survival Compared to Intensive Remission Induction Chemotherapy Followed By Allo-HCT: Results from the Randomized Phase III ASAP Trial

Matthias Stelljes, Jan Moritz Middeke, Gesine Bug, Eva-Maria Wagner, Lutz Peter Mueller, Schmid Christoph, Stefan W. Krause, Wolfgang Bethge, Edgar Jost, Uwe Platzbecker, Stefan Klein, Jörg Schubert, Judith Niederland, Martin Kaufmann, Kerstin Schäfer-Eckart, Markus Schaich, Henning Baldauf, Friedrich Stölzel, Cathleen Petzold, Christoph Röllig, Nael Alakel, Björn Steffen, Beate Hauptrock, Christian Reicherts, Christoph Schliemann, Hubert Serve, Alexander H. Schmidt, Martin Bornhäuser, Jan-Henrik Mikesch, Johannes Schetelig
Journal: Blood
Blood (2022) 140 (Supplement 1): 9–11.
https://doi.org/10.1182/blood-2022-159962
Published: 2022
Journal Articles

Artificial Intelligence Methods to Estimate Overall Mortality and Non-Relapse Mortality Following Allogeneic Hematopoietic Cell Transplantation in the Modern Era: An EBMT Transplant Complications Working Party Study

Blanca Rius Sansalvador, Alberto Mussetti, Victor Moreno, Christophe Peczynski, Emmanuelle Polge, Nicolaus Kröger, Didier Blaise, Régis Peffault de Latour, Alexander D. Kulagin, Ashrafsadat Mousavi, Matthias Stelljes, Rose-Marie Hamladji, Martin Bornhäuser, Urpu Salmenniemi, Henrik Sengeloev, Edouard Forcade, Uwe Platzbecker, Péter Reményi, Emanuele Angelucci, Patrice Chevallier, Ibrahim Yakoub-Agha, Charles Craddock, Fabio Ciceri, Thomas Schroeder, Mahmoud Aljurf, Ivan Moiseev, Olaf Penack, Helene Schoemans, Mohamad Mohty, Bertram Glass, Anna Sureda, Grzegorz W Basak, Zinaida Peric
Journal: Blood
Blood (2022) 140 (Supplement 1): 7734–7737.
https://doi.org/10.1182/blood-2022-168601
Published: 2022
Journal Articles

Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia

Leo Ruhnke, Julia Frimmel, Christoph Röllig, Brigitte Mohr, Heidi Altmann, David Poitz, Sven Zukunft, Katrin Schranz, Sebastian Vosberg, Karsten Spiekermann, Michael von Bergwelt, Edgar Jost, Sabine Dressler, Kerstin Schäfer-Eckart, Triantafyllos Chavakis, Daniela Aust, Korinna Jöhrens, Gustavo Baretton, Martin Bornhäuser, Philipp A. Greif, Friedrich Stölzel, Sylvia Herold, Lisa Wagenführ
Journal: Blood
Blood (2022) 140 (Supplement 1): 3454–3455.
https://doi.org/10.1182/blood-2022-166271
Published: 2022
Journal Articles

Proteomic Characterization of Acute Myeloid Leukemia

Sebastian Wolf, Ashok Kumar Jayavelu, Florian Buettner, Gabriela Alexe, Björn Häupl, Constanze Schneider, Anne C Wilke, Alena Zindel, Dominique Jahn, Bianca Splettstoesser, Julius Christoph Enssle, Anjali Cremer, Christoph Röllig, Christian Thiede, Björn Steffen, Martin Bornhäuser, Henning Urlaub, Kimberly Stegmaier, Hubert Serve, Matthias Mann, Thomas Oellerich
Journal: Blood
Blood (2022) 140 (Supplement 1): 3456–3457.
https://doi.org/10.1182/blood-2022-169242
Published: 2022