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Arterial thromboembolic events preceding the diagnosis of cancer in older persons
Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD
The natural history of asymptomatic central venous catheter–related thrombosis in critically ill children
Issue Archive
February 21 2019
In this Issue
Table of Contents
BLOOD COMMENTARIES
PLENARY PAPER
CLINICAL TRIALS AND OBSERVATIONS
Arterial thromboembolic events preceding the diagnosis of cancer in older persons
Clinical Trials & Observations
Babak B. Navi,Anne S. Reiner,Hooman Kamel,Costantino Iadecola,Peter M. Okin,Scott T. Tagawa,Katherine S. Panageas,Lisa M. DeAngelis
BLOOD SPOTLIGHT
HOW I TREAT
HEMATOPOIESIS AND STEM CELLS
BCAS2 is essential for hematopoietic stem and progenitor cell maintenance during zebrafish embryogenesis
Shanshan Yu,Tao Jiang,Danna Jia,Yunqiao Han,Fei Liu,Yuwen Huang,Zhen Qu,Yuntong Zhao,Jiayi Tu,Yuexia Lv,Jingzhen Li,Xuebin Hu,Zhaojing Lu,Shanshan Han,Yayun Qin,Xiliang Liu,Shanglun Xie,Qing K. Wang,Zhaohui Tang,Daji Luo,Mugen Liu
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL
Viola Close,William Close,Sabrina Julia Kugler,Michaela Reichenzeller,Deyan Yordanov Yosifov,Johannes Bloehdorn,Leiling Pan,Eugen Tausch,Mike-Andrew Westhoff,Hartmut Döhner,Stephan Stilgenbauer,Franz Oswald,Daniel Mertens
MYELOID NEOPLASIA
Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD
Clinical Trials & Observations
Richard F. Schlenk,on behalf of the German-Austrian AML Study Group,Daniela Weber,on behalf of the German-Austrian AML Study Group,Walter Fiedler,on behalf of the German-Austrian AML Study Group,Helmut R. Salih,on behalf of the German-Austrian AML Study Group,Gerald Wulf,on behalf of the German-Austrian AML Study Group,Hans Salwender,on behalf of the German-Austrian AML Study Group,Thomas Schroeder,on behalf of the German-Austrian AML Study Group,Thomas Kindler,on behalf of the German-Austrian AML Study Group,Michael Lübbert,on behalf of the German-Austrian AML Study Group,Dominik Wolf,on behalf of the German-Austrian AML Study Group,Jörg Westermann,on behalf of the German-Austrian AML Study Group,Doris Kraemer,on behalf of the German-Austrian AML Study Group,Katharina S. Götze,on behalf of the German-Austrian AML Study Group,Heinz-August Horst,on behalf of the German-Austrian AML Study Group,Jürgen Krauter,on behalf of the German-Austrian AML Study Group,Michael Girschikofsky,on behalf of the German-Austrian AML Study Group,Mark Ringhoffer,on behalf of the German-Austrian AML Study Group,Thomas Südhoff,on behalf of the German-Austrian AML Study Group,Gerhard Held,on behalf of the German-Austrian AML Study Group,Hans-Günter Derigs,on behalf of the German-Austrian AML Study Group,Roland Schroers,on behalf of the German-Austrian AML Study Group,Richard Greil,on behalf of the German-Austrian AML Study Group,Martin Grießhammer,on behalf of the German-Austrian AML Study Group,Elisabeth Lange,on behalf of the German-Austrian AML Study Group,Alexander Burchardt,on behalf of the German-Austrian AML Study Group,Uwe Martens,on behalf of the German-Austrian AML Study Group,Bernd Hertenstein,on behalf of the German-Austrian AML Study Group,Lore Marretta,on behalf of the German-Austrian AML Study Group,Michael Heuser,on behalf of the German-Austrian AML Study Group,Felicitas Thol,on behalf of the German-Austrian AML Study Group,Verena I. Gaidzik,on behalf of the German-Austrian AML Study Group,Wolfgang Herr,on behalf of the German-Austrian AML Study Group,Julia Krzykalla,on behalf of the German-Austrian AML Study Group,Axel Benner,on behalf of the German-Austrian AML Study Group,Konstanze Döhner,on behalf of the German-Austrian AML Study Group,Arnold Ganser,on behalf of the German-Austrian AML Study Group,Peter Paschka,on behalf of the German-Austrian AML Study Group,Hartmut Döhner,on behalf of the German-Austrian AML Study Group
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
The natural history of asymptomatic central venous catheter–related thrombosis in critically ill children
CME
Clinical Trials & Observations
TRANSPLANTATION
LETTER TO BLOOD
BLOOD WORK
CONTINUING MEDICAL EDUCATION (CME) QUESTIONS
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Cover Image
Cover Image
This whole-mount in situ hybridization image with a probe targeting cmyb (cellular progenitor of the avian myeloblastosis virus oncogene) reveals a reduced number of hematopoietic stem and progenitor cells in the caudal hematopoietic tissue of bcas2 (breast carcinoma amplified sequence 2) knockout zebrafish embryos 3 days after fertilization. See the article by Yu et al on page 805.
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