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Mike-Andrew Westhoff
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Journal Articles

FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL

Viola Close, William Close, Sabrina Julia Kugler, Michaela Reichenzeller, Deyan Yordanov Yosifov, Johannes Bloehdorn, Leiling Pan, Eugen Tausch, Mike-Andrew Westhoff, Hartmut Döhner, Stephan Stilgenbauer, Franz Oswald, Daniel Mertens
Journal: Blood
Blood (2019) 133 (8): 830–839.
https://doi.org/10.1182/blood-2018-09-874529
Published: 2019
Includes: Supplemental data
Journal Articles

NOTCH1 Signaling Is Activated in CLL By Mutations of FBXW7 and Low Expression of USP28 at 11q23

Viola Close, MSc, William Close, MSc, Sabrina Julia Kugler, PhD, Michaela Reichenzeller, PhD, Deyan Yordanov Yosifov, PhD, Johannes Bloehdorn, MD, Leiling Pan, MSc, Eugen Tausch, MD, Mike-Andrew Westhoff, PhD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD PhD, Franz Oswald, PhD, Daniel Mertens
Journal: Blood
Blood (2018) 132 (Supplement 1): 946.
https://doi.org/10.1182/blood-2018-99-114491
Published: 2018
Journal Articles

Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debatin
Journal: Blood
Blood (2006) 108 (10): 3504–3513.
https://doi.org/10.1182/blood-2006-05-021691
Published: 2006